2023
Modalities to Deliver Cell Therapy for Treatment of Chronic Limb Threatening Ischemia
Setia O, Lee S, Dardik A. Modalities to Deliver Cell Therapy for Treatment of Chronic Limb Threatening Ischemia. Advances In Wound Care 2023, 13: 253-279. PMID: 37002893, PMCID: PMC11305013, DOI: 10.1089/wound.2022.0114.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsChronic limb threatening ischemiaPeripheral arterial diseaseSevere peripheral arterial diseaseLimb threatening ischemiaClinical trialsCell therapyStem cell therapyIschemic limbsFeasible therapeutic alternativePromising treatment optionPre-clinical studiesCell deliveryPAD patientsArterial diseaseClinical benefitTreatment optionsSurgical methodsTherapeutic alternativeBest modalityHigh riskLimb lossSevere formTherapeutic benefitPatientsTherapy
2021
Stem cell therapy in vascular diseases
Navarro T, Lopes L, Dardik A. Stem cell therapy in vascular diseases. Revista Ciências Em Saúde 2021, 11: 1-2. DOI: 10.21876/rcshci.v11i4.1247.Commentaries, Editorials and LettersChapter 12 Induced pluripotent stem cells in wound healing
Gao X, Gorecka J, Cheema U, Gu Y, Wu Y, Dardik A. Chapter 12 Induced pluripotent stem cells in wound healing. 2021, 269-290. DOI: 10.1016/b978-0-12-822229-4.00003-6.ChaptersPluripotent stem cellsCell-free extracellular vesiclesIdeal delivery platformSomatic donor cellsStem cellsDestruction of embryosPluripotent stem cell populationDelivery platformDelivery scaffoldsRegenerative medicineIPSC technologyWidespread clinical adoptionTissue regenerationStem cell sourceTremendous advantagesCell sourceCell therapyPromising approachExciting new strategyIPSCsStem cell populationNew strategyExtracellular vesiclesUndifferentiated cellsTranslational potential
2020
Stem Cell Therapy to Improve Acute Myocardial Infarction Remodeling
Gorecka J, Dardik A. Stem Cell Therapy to Improve Acute Myocardial Infarction Remodeling. 2020, 299-329. DOI: 10.1007/978-3-030-56954-9_14.ChaptersHeart failureMyocardial infarctionClinical trialsEjection fractionCellular sourceCell therapyEnd-stage pathologyCause of deathStem cell efficacyStem cell treatmentStem cell therapyMI injuryVentricular dilationModest efficacyMyocardial recoveryHeart diseaseRemodeling changesSurgical careIschemic environmentAdult myocardiumDelivery methodsCell efficacyCell treatmentLack of standardizationTrialsStem Cell Delivery Techniques for Stroke and Peripheral Artery Disease
Lee S, Fereydooni A, Dardik A. Stem Cell Delivery Techniques for Stroke and Peripheral Artery Disease. 2020, 69-103. DOI: 10.1007/978-3-030-56954-9_3.ChaptersPeripheral artery diseaseArtery diseaseImpact of patientStem cellsVascular diseaseTherapeutic effectHuman trialsOptimal doseTarget organsPharmaceutic agentsCell therapyDiseaseCell delivery techniquesStrokeCell factorPatientsTherapyDelivery techniquesDiverse populationsDelivery methodsCellsDelivery optionsDoseTrialsIntroduction to Stem Cell Therapy and Its Application in Vascular Diseases
Lopes L, Navarro T, Dardik A. Introduction to Stem Cell Therapy and Its Application in Vascular Diseases. 2020, 1-32. DOI: 10.1007/978-3-030-56954-9_1.ChaptersVascular diseaseCell therapyInnovative therapeutic strategiesStem cell therapyCell-based regenerative strategiesPatient characteristicsTherapeutic strategiesTherapeutic risksAdministration routeCell-intrinsic propertiesTherapy protocolsTherapyDiseaseRegenerative strategiesCell typesCell culturesMechanisms of regenerationStem Cell Therapy for Thromboangiitis Obliterans (Buerger’s Disease)
Dash B, Peyvandi H, Duan K, Richardson E, Ndon S, Gabrick K, Faz A, Persing J, Dardik A, Hsia H. Stem Cell Therapy for Thromboangiitis Obliterans (Buerger’s Disease). Processes 2020, 8: 1408. DOI: 10.3390/pr8111408.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsThromboangiitis obliteransYoung male smokersBuerger's diseaseImmunomodulatory approachesMale smokersSurgical bypassPathological findingsTreatment modalitiesVascular diseaseDefinitive cureLower extremitiesMedium arteriesLesion treatmentTherapeutic modalitiesTAO treatmentTherapeutic angiogenesisCell therapyDiseaseObliteransStem cellsCurrent knowledgeModalitiesTreatmentPotential optionVasculitis