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African-American adult patients are more likely than white patients to receive substandard gastrointestinal cancer surgery, according a large study led by researchers at Yale Cancer Center. The findings are reported today in the journal JAMA Network Open.

Colon cancer has been undergoing a similar subdivision. Researchers have known for years that colorectal cancer is the third most common cancer diagnosis in the United States and the second leading cause of cancer-related deaths. The National Cancer Institute estimates 149,500 new cases in 2021 and 53,000 deaths.

Researchers studying COVID-19 patients have found a metabolic pathway that is highly correlated with immune responses only in male patients, a group known to be more likely to suffer severe cases and die of the disease, representing a potential target for therapeutic intervention.

Colon and rectal cancers are rising in younger adults, though researchers aren’t sure why. A new study of women and diet suggests that sugar-sweetened drinks may play a role.

If the challenges of the past year have taught us anything, it is that we must continue working to understand all that we can about health and disease. And when it comes to sex and gender, we should not wait for the next crisis before addressing these critical components of our health.

Yale researchers across a range of disciplines are coming together to explore the important role of microbial metabolites in our microbiota—the trillions of bacterial cells that colonize our intestines.

WHRY pilot project recipients have received major competitive funding support to advance their work toward clinical applications.

Caroline Johnson, Ph.D., Assistant Professor of Epidemiology in the Department of Environmental Health Sciences at Yale School of Public Health and a member of Yale Cancer Center’s Cancer Microbiology Research Program, has received a four-year, $792,000 Research Scholar Grant from the American Cancer Society (ACS).

Researchers have found that colon cancer tumor cells produce energy for growth differently in women and men, and that this difference is associated with a more aggressive form of tumor growth with a higher incidence in women.