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A groundbreaking new database could lead to vast improvements in precision oncology by documenting sex-based differences in cancer treatment efficacy, biomarkers, risk factors, and microbial influences across 71 cancer types. The database — created by researchers at the Yale School of Public Health, Yale School of Medicine, and international collaborators — addresses a significant gap in current research and demonstrates how biological sex can comprehensively impact cancer onset, progression, and therapeutic outcomes.

A new study from the Yale School of Public Health (YSPH) offers fresh insights into our understanding of colorectal cancer (CRC) that challenge the conventional right-sided and left-sided classifications of the disease.

Yale Cancer Center researchers will present their new cancer research findings at the 2024 AACR annual meeting. A few of the presenting YCC researchers offer their key study takeaways and the significance for patients and oncologists.

In a new study by researchers at the Yale School of Public Health, two “forever chemicals” spurred cancer cells in the lab to migrate to new positions, an indication that the chemicals could contribute to cancer metastasis in living organisms.

Colon cancers that spread to the liver may be substantially different depending on the location where cancerous cells originate, according to new research.

Yale researchers identify diet-related metabolites associated with paraben concentrations in the urine of pregnant women. Parabens can disrupt endocrine activity in the body and they have been associated with changes in fertility in women.

Around 40% of colorectal cancer patients have a particular gene mutation. A new study shows it’s linked to reduced cell death and worse survival rates in men.

African-American adult patients are more likely than white patients to receive substandard gastrointestinal cancer surgery, according a large study led by researchers at Yale Cancer Center. The findings are reported today in the journal JAMA Network Open.

Colon cancer has been undergoing a similar subdivision. Researchers have known for years that colorectal cancer is the third most common cancer diagnosis in the United States and the second leading cause of cancer-related deaths. The National Cancer Institute estimates 149,500 new cases in 2021 and 53,000 deaths.