2000
GDP Dissociation Inhibitor Domain II Required for Rab GTPase Recycling*
Gilbert P, Burd C. GDP Dissociation Inhibitor Domain II Required for Rab GTPase Recycling*. Journal Of Biological Chemistry 2000, 276: 8014-8020. PMID: 11116150, DOI: 10.1074/jbc.m008845200.Peer-Reviewed Original ResearchConceptsGDP dissociation inhibitorDomain IIRab GDP dissociation inhibitorRab bindingRab localizationGenetic screenRab GTPasesTransport intermediatesDissociation inhibitorDeletion strainAcceptor membranesCytosolic poolVps21pVesicle fusionRabDomain IMutantsGdi1pYpt1pGeneral defectOrganellesCytosolMembraneDistinct subsetsSec4p
1999
Molecular Dissection of Guanine Nucleotide Dissociation Inhibitor Function in Vivo Rab-INDEPENDENT BINDING TO MEMBRANES AND ROLE OF RAB RECYCLING FACTORS*
Luan P, Balch W, Emr S, Burd C. Molecular Dissection of Guanine Nucleotide Dissociation Inhibitor Function in Vivo Rab-INDEPENDENT BINDING TO MEMBRANES AND ROLE OF RAB RECYCLING FACTORS*. Journal Of Biological Chemistry 1999, 274: 14806-14817. PMID: 10329679, DOI: 10.1074/jbc.274.21.14806.Peer-Reviewed Original ResearchConceptsRecycling factorNucleotide Dissociation InhibitorFusion of vesiclesSite-directed mutagenesisAmino acid residuesRab deliveryDistinct RabsRab GTPasesRab proteinsRab-GDPDissociation inhibitorMembrane associationEssential proteinsMolecular dissectionEndocytic pathwayGDI functionAcid residuesRabCellular membranesDominant inhibitionMultiple effectorsRate of recyclingInhibitor functionProteinEndogenous pool