Featured Publications
Catalysis-Independent ENPP1 Protein Signaling Regulates Mammalian Bone Mass
Zimmerman K*, Liu X*, von Kroge S*, Stabach P, Lester ER, Chu EY, Srivastava S, Somerman MJ, Tommasini SM, Busse B, Schinke T, Carpenter TO, Oheim R, Braddock DT. Catalysis‐Independent ENPP1 Protein Signaling Regulates Mammalian Bone Mass. Journal Of Bone And Mineral Research 2020, 37: 1733-1749. PMID: 35773783, PMCID: PMC9709593, DOI: 10.1002/jbmr.4640.Peer-Reviewed Original ResearchA dual-acting DNASE1/DNASE1L3 biologic prevents autoimmunity and death in genetic and induced lupus models
Stabach P, Sims D, Gomez-Bañuelos E, Zehentmeier S, Dammen-Brower K, Bernhisel A, Kujawski S, Lopez S, Petri M, Goldman D, Lester E, Le Q, Ishaq T, Kim H, Srivastava S, Kumar D, Pereira J, Yarema K, Koumpouras F, Andrade F, Braddock D. A dual-acting DNASE1/DNASE1L3 biologic prevents autoimmunity and death in genetic and induced lupus models. JCI Insight 2024, 9: e177003. PMID: 38888971, PMCID: PMC11383374, DOI: 10.1172/jci.insight.177003.Peer-Reviewed Original ResearchSystemic lupus erythematosusDNASE1L3 deficiencySporadic systemic lupus erythematosusAssociated with systemic lupus erythematosusChromatin degradationDNA accumulationDevelopment of lupusPristane-induced lupusSelf-DNACell free DNAHuman isoformsSystemic lupus erythematosus plasmasDouble knockout miceDNASE1L3Pathogenic effectsFree DNALupus modelEnzymeInducible lupus modelAdult patientsLupus erythematosusKnockout micePediatric populationAutoimmune diseasesDNAExpression kinetics reveal the self-adaptive role of β cells during the progression of diabetes.
Srivastava S, Pandey H, Tripathi YB. Expression kinetics reveal the self-adaptive role of β cells during the progression of diabetes. Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie 2018, 106: 472-482. PMID: 29990835, DOI: 10.1016/j.biopha.2018.06.168.Peer-Reviewed Original ResearchIncretin hormones receptor signaling plays the key role in antidiabetic potential of PTY-2 against STZ-induced pancreatitis.
Srivastava S, Shree P, Pandey H, Tripathi YB. Incretin hormones receptor signaling plays the key role in antidiabetic potential of PTY-2 against STZ-induced pancreatitis. Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie 2018, 97: 330-338. PMID: 29091882, DOI: 10.1016/j.biopha.2017.10.071.Peer-Reviewed Original ResearchGLP 1 Regulated Intestinal Cell's Insulin Expression and Selfadaptation before the Onset of Type 2 Diabetes.
Srivastava S, Pandey H, Singh SK, Tripathi YB. GLP 1 Regulated Intestinal Cell's Insulin Expression and Selfadaptation before the Onset of Type 2 Diabetes. Advanced Pharmaceutical Bulletin 2019, 9: 325-330. PMID: 31380261, PMCID: PMC6664108, DOI: 10.15171/apb.2019.039.Peer-Reviewed Original ResearchActive phytochemicals of Pueraria tuberosa for DPP-IV inhibition: in silico and experimental approach.
Srivastava S, Shree P, Tripathi YB. Active phytochemicals of Pueraria tuberosa for DPP-IV inhibition: in silico and experimental approach. Journal Of Diabetes And Metabolic Disorders 2017, 16: 46. PMID: 29201861, PMCID: PMC5697100, DOI: 10.1186/s40200-017-0328-0.Peer-Reviewed Original ResearchAnti-oxidant, anti-apoptotic, anti-hypoxic and anti-inflammatory conditions induced by PTY-2 against STZ-induced stress in islets.
Srivastava S, Pandey H, Singh SK, Tripathi YB. Anti-oxidant, anti-apoptotic, anti-hypoxic and anti-inflammatory conditions induced by PTY-2 against STZ-induced stress in islets. Bioscience Trends 2019, 13: 382-393. PMID: 31597821, DOI: 10.5582/bst.2019.01181.Peer-Reviewed Original ResearchPueraria tuberosa as Dipeptidyl-Peptidase-IV Inhibitor Prevents Streptozotocin-Induced Intestinal Stress.
Srivastava S, Pandey H, Singh SK, Tripathi YB. Pueraria tuberosa as dipeptidyl-peptidase-IV inhibitor prevents streptozotocin-induced intestinal stress. Open Access Macedonian Journal of Medical Sciences. 2021;9(A):28-34.Peer-Reviewed Original ResearchRevolutionizing Immunotherapy: Unveiling New Horizons, Confronting Challenges, and Navigating Therapeutic Frontiers in CAR-T Cell-Based Gene Therapies
Srivastava S*, Tyagi A*, Pawar VA*, Khan NH*, Arora K, Verma C, Kumar V. Revolutionizing Immunotherapy: Unveiling New Horizons, Confronting Challenges, and Navigating Therapeutic Frontiers in CAR-T Cell-Based Gene Therapies. Immunotargets Ther 2024, 13: 413-433. PMID: 39219644, DOI: 10.2147/ITT.S474659.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsImmune Modulatory Effects of Ketogenic Diet in Different Disease Conditions
Srivastava, S*, Pawar, V.A*, Tyagi, A*, Sharma, K.P*, Kumar, V.; Shukla, S.K. Immune Modulatory Effects of Ketogenic Diet in Different Disease Conditions. Immuno 2023, 3, 1-15. https://doi.org/10.3390/immuno3010001Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2024
Hepatoprotective role of Pueraria tuberosa water extract (PTWE) in CCl4-induced liver injury through different signaling pathways
Prerana Aditi, Vahab Ali, Mayank Choubey, Munichandra Babu Tirumalasetty, Harsh Pandey, Shivani Srivastava, Yamini Bhusan Tripathi. Hepatoprotective role of Pueraria tuberosa water extract (PTWE) in CCl4-induced liver injury through different signaling pathways. Advances in Traditional Medicine. 2024.Peer-Reviewed Original ResearchExploring the Molecular Link Between Diabetes and Erectile Dysfunction Through Single-Cell Transcriptome Analysis.
Begum M, Choubey M, Tirumalasetty MB, Arbee S, Sadik S, Mohib MM, Srivastava S, Minhaz N, Alam R, Mohiuddin MS. Exploring the Molecular Link Between Diabetes and Erectile Dysfunction Through Single-Cell Transcriptome Analysis. Genes (Basel) 2024, 15 PMID: 39766863, DOI: 10.3390/genes15121596.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsHost Immune Response to Dengue Virus Infection: Friend or Foe?
Priya Dhole*^, Amir Zaidi*, H.K. Nariya, Shruti Sinha, Sandhya Jinesh, Shivani Srivastava^. Host Immune Response to Dengue Virus Infection: Friend or Foe? Immuno. 2024; 4(4):549-577.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsClinico-Pathological Factors and AR-LBD Mutations in Early and Late Castration-Resistant Prostate Cancer.
Deswal M, Yadav D, Kumar V, Meenu M, Tanwar P, Srivastava S, Singh P, Sandeep K. Clinico-Pathological Factors and AR-LBD Mutations in Early and Late Castration-Resistant Prostate Cancer. Cancer Manag Res 2024, 16: 1509-1516. PMID: 39464307, DOI: 10.2147/CMAR.S477439.Peer-Reviewed Original Research
2023
Cancer Vaccines in the Immunotherapy Era: Promise and Potential
Verma C* , Pawar VA*, Srivastava S, Tyagi A, Kaushik G, Shukla SK, Kumar V. Cancer Vaccines in the Immunotherapy Era: Promise and Potential. Vaccines (Basel) 2023, 11 PMID: 38140187, DOI: 10.3390/vaccines11121783.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsGut Microbiome and the Metabolic Syndrome
Srivastava S, Aditi P, Yadav D. Gut Microbiome and Metabolic Syndrome. The Metabolic Syndrome: Dietary Supplements and Food Ingredients. 2023.ChaptersEfficacy of Bioactive Compounds in the Regulation of Metabolism and Pathophysiology in Cardiovascular Diseases
Pawar VA*, Srivastava S*, Tyagi A*, Tayal R*, Shukla SK, Kumar V. Efficacy of Bioactive Compounds in the Regulation of Metabolism and Pathophysiology in Cardiovascular Diseases. Curr Cardiol Rep 2023 PMID: 37458865, DOI: 10.1007/s11886-023-01917-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2021
Epigenetic Regulation of Gut Microbial Dysbiosis.
Srivastava S, Singh A, Sandeep K, Yadav D. Epigenetic Regulation of Gut Microbial Dysbiosis. Indian Journal Of Microbiology 2021, 1-5. PMID: 33612870, PMCID: PMC7877904, DOI: 10.1007/s12088-021-00920-y.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2020
Toxicity profile of honey and ghee, when taken together in equal ratio.
Aditi P, Srivastava S, Pandey H, Tripathi YB. Toxicity profile of honey and ghee, when taken together in equal ratio. Toxicology Reports 2020, 7: 624-636. PMID: 32455119, PMCID: PMC7235625, DOI: 10.1016/j.toxrep.2020.04.002.Peer-Reviewed Original ResearchBeta Cells and Diabetes
Srivastava S, Yadav D, Sandeep K, Pandey H, Singh SK, Tripathi YB. Beta Cells and Diabetes. Nutraceuticals and Dietary Supplements: Applications in Health Improvement and Disease Management. 2020 Nov 5:295.Chapters