Hajime Kato, MD, PhD
Associate Research Scientist in PathologyCards
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Research
Publications
2025
The prevalence of ENPP1 deficiency in humans with Ossification of the Posterior Longitudinal Ligament and the preclinical efficacy of ENPP1 enzyme therapy in murine Ossification of the Posterior Longitudinal Ligament
Srivastava S, Kato H, von Kroge S, Weise K, Stabach P, Lopez S, O’Brien K, Lester E, Kim H, Ishaq T, Dammen-Brower K, Schinke T, Kimura S, Miyahara J, Doi T, Oshima Y, Yarema K, Carpenter T, Sabbagh Y, Tommasini S, Ito N, Oheim R, Braddock D. The prevalence of ENPP1 deficiency in humans with Ossification of the Posterior Longitudinal Ligament and the preclinical efficacy of ENPP1 enzyme therapy in murine Ossification of the Posterior Longitudinal Ligament. Journal Of Bone And Mineral Research 2025, 41: 651-665. PMID: 41251406, PMCID: PMC13084927, DOI: 10.1093/jbmr/zjaf168.Peer-Reviewed Original ResearchPHEX Protein in the Parathyroid Gland Contributes to Phosphate Sensing
Irie K, Kato H, Adachi N, Kimura S, Hoshino Y, Hidaka N, Tanaka S, Nangaku M, Saito T, Makita N, Ito N. PHEX Protein in the Parathyroid Gland Contributes to Phosphate Sensing. The Journal Of Clinical Endocrinology & Metabolism 2025, 111: e1-e8. PMID: 40512822, DOI: 10.1210/clinem/dgaf357.Peer-Reviewed Original ResearchAcquired Osteomalacia Associated with Autoantibodies against PHEX
Hoshino Y, Okamoto K, Ogawa T, Kato H, Irie K, Watanabe S, Kimura S, Hidaka N, Kinoshita Y, Kobayashi H, Hagiwara D, Kogawa M, Takayanagi H, Tanaka S, Nangaku M, Makita N, Burbelo P, Saito T, Ito N. Acquired Osteomalacia Associated with Autoantibodies against PHEX. The New England Journal Of Medicine 2025, 392: 513-515. PMID: 39879599, PMCID: PMC11781776, DOI: 10.1056/nejmc2405746.Commentaries, Editorials and LettersExcess fibroblast growth factor 23 in alcoholic osteomalacia is derived from the bone
Hidaka N, Oyama Y, Koga M, Kondo N, Yasunaga Y, Shimakura T, Yamamoto N, Takahashi H, Iwafuchi Y, Watanabe S, Kimura S, Hoshino Y, Kato H, Kinoshita Y, Kobayashi H, Tanaka T, Ushiku T, Nangaku M, Tanaka S, Makita N, Saito T, Ito N. Excess fibroblast growth factor 23 in alcoholic osteomalacia is derived from the bone. JBMR Plus 2025, 9: ziaf010. PMID: 39963340, PMCID: PMC11831984, DOI: 10.1093/jbmrpl/ziaf010.Peer-Reviewed Original Research
2024
Effect of Mutation Type on Ectopic Ossification Among Adult Patients With X-Linked Hypophosphatemia
Kato H, Ishihara Y, Ohata Y, Irie K, Watanabe S, Kimura S, Hoshino Y, Hidaka N, Kinoshita Y, Taniguchi Y, Kobayashi H, Braddock D, Kubota T, Ozono K, Nangaku M, Makita N, Ito N. Effect of Mutation Type on Ectopic Ossification Among Adult Patients With X-Linked Hypophosphatemia. Journal Of The Endocrine Society 2024, 8: bvae184. PMID: 39498416, PMCID: PMC11532897, DOI: 10.1210/jendso/bvae184.Peer-Reviewed Original ResearchLatent metabolic bone disease, skeletal dysplasia and other conditions related to low bone formation among 38 patients with subtrochanteric femoral fractures: a retrospective observational study
Kimura S, Sunouchi T, Watanabe S, Hoshino Y, Hidaka N, Kato H, Takeda S, Nangaku M, Makita N, Azuma K, Kojima T, Matsubara T, Saito T, Ito N. Latent metabolic bone disease, skeletal dysplasia and other conditions related to low bone formation among 38 patients with subtrochanteric femoral fractures: a retrospective observational study. Osteoporosis International 2024, 35: 1633-1643. PMID: 38951164, PMCID: PMC11364693, DOI: 10.1007/s00198-024-07168-4.Peer-Reviewed Original ResearchCardiovascular Outcomes of KCNJ5 Mutated Aldosterone-Producing Adenoma: A Systematic Review
Kato H, Kitamoto T, Kimura S, Sunouchi T, Hoshino Y, Hidaka N, Tsurutani Y, Ito N, Makita N, Nishikawa T, Nangaku M, Inoue K. Cardiovascular Outcomes of KCNJ5 Mutated Aldosterone-Producing Adenoma: A Systematic Review. Endocrine Practice 2024, 30: 670-678. PMID: 38657793, DOI: 10.1016/j.eprac.2024.04.007.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAcquired Forms of Fibroblast Growth Factor 23-Related Hypophosphatemic Osteomalacia
Ito N, Hidaka N, Kato H. Acquired Forms of Fibroblast Growth Factor 23-Related Hypophosphatemic Osteomalacia. Endocrinology And Metabolism 2024, 39: 255-261. PMID: 38467164, PMCID: PMC11066443, DOI: 10.3803/enm.2023.1908.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsExtended curettage for tumour-induced osteomalacia in the bone
Okajima K, Kobayashi H, Ito N, Kato H, Ishibashi Y, Zhang L, Tsuda Y, Tanaka S. Extended curettage for tumour-induced osteomalacia in the bone. Japanese Journal Of Clinical Oncology 2024, 54: 463-470. PMID: 38266040, DOI: 10.1093/jjco/hyad180.Peer-Reviewed Original ResearchFGF-23, Left Ventricular Hypertrophy, and Mortality in Patients With CKD: A Revisit With Mediation Analysis
Hidaka, N, Inoue, K, Kato, H. et al. FGF-23, Left Ventricular Hypertrophy, and Mortality in Patients With CKD: A Revisit With Mediation Analysis. JACC Adv. 2024 Jan, 3 (1) . https://doi.org/10.1016/j.jacadv.2023.100747Peer-Reviewed Original Research
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