Jae-Sung Yi, PhD
Staff Scientist I, Research CORESCards
About
Research
Publications
2026
NAPRT expression and epigenetic regulation in pediatric rhabdomyosarcoma as a potential biomarker for NAMPT inhibition
Kim A, Bhardwaj P, Rehman S, Zhao S, Lucas K, Noronha K, Bhatt D, Friedman S, Morotti R, Sundaram R, Dela Cruz F, Feinberg T, Ramakrishnan S, Xue W, Barkauskas D, Hall D, Shern J, Sun W, Barr F, Yi J, Spurrier J, Yu A, Brenner C, Heer C, Heske C, Vasquez J. NAPRT expression and epigenetic regulation in pediatric rhabdomyosarcoma as a potential biomarker for NAMPT inhibition. Molecular Cancer Therapeutics 2026, 10.1158/1535-7163.mct-25-0619. PMID: 42017774, PMCID: PMC13184901, DOI: 10.1158/1535-7163.mct-25-0619.Peer-Reviewed Original Research
2025
SHP2 genetic variants in NSML-associated RASopathies disrupt the PZR–IRX transcription factor signaling axis
Perla S, Stiegler A, Yi J, Enyenihi L, Zhang L, Riaz M, An E, Qyang Y, Boggon T, Bennett A. SHP2 genetic variants in NSML-associated RASopathies disrupt the PZR–IRX transcription factor signaling axis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2503631122. PMID: 40854126, PMCID: PMC12415285, DOI: 10.1073/pnas.2503631122.Peer-Reviewed Original Research
2023
Identification of Protein Tyrosine Phosphatase (PTP) Substrates
Perla S, Qiu B, Dorry S, Yi J, Bennett A. Identification of Protein Tyrosine Phosphatase (PTP) Substrates. Methods In Molecular Biology 2023, 2743: 123-133. PMID: 38147212, PMCID: PMC11610242, DOI: 10.1007/978-1-0716-3569-8_8.Chapters
2022
An Assessment of the Therapeutic Landscape for the Treatment of Heart Disease in the RASopathies
Yi JS, Perla S, Bennett AM. An Assessment of the Therapeutic Landscape for the Treatment of Heart Disease in the RASopathies. Cardiovascular Drugs And Therapy 2022, 37: 1193-1204. PMID: 35156148, PMCID: PMC11726350, DOI: 10.1007/s10557-022-07324-0.Peer-Reviewed Original Research
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