ILD Publications

2022

Lung Microenvironments and Disease Progression in Fibrotic Hypersensitivity Pneumonitis.De Sadeleer LJ, McDonough JE, Schupp JC, Yan X, Vanstapel A, Van Herck A, Everaerts S, Geudens V, Sacreas A, Goos T, Aelbrecht C, Nawrot TS, Martens DS, Schols D, Claes S, Verschakelen JA, Verbeken EK, Ackermann M, Decottignies A, Mahieu M, Hackett TL, Hogg JC, Vanaudenaerde BM, Verleden SE, Kaminski N, Wuyts WA. Am J Respir Crit Care Med. 2022 Jan 1. PMID: 34724391.
Global Rheumatology Research: Frontiers, Challenges, and Opportunities.Bilsborrow JB, Peláez-Ballestas I, Pons-Estel B, Scott C, Tian X, Alarcon GS, Bucala R, Lewandowski LB, Hsieh E. Arthritis Rheumatol. 2022 Jan; 2021 Dec 8. PMID: 34535973.
Persistent Exertional Intolerance After COVID-19: Insights From Invasive Cardiopulmonary Exercise Testing.Singh I, Joseph P, Heerdt PM, Cullinan M, Lutchmansingh DD, Gulati M, Possick JD, Systrom DM, Waxman AB. Chest. 2022 Jan; 2021 Aug 11. PMID: 34389297.

2021

Canonical (CD74/CD44) and Non-Canonical (CXCR2, 4 and 7) MIF Receptors Are Differentially Expressed in Rheumatoid Arthritis Patients Evaluated by DAS28-ESR.Sánchez-Zuno GA, Bucala R, Hernández-Bello J, Román-Fernández IV, García-Chagollán M, Nicoletti F, Matuz-Flores MG, García-Arellano S, Esparza-Michel JA, Cerpa-Cruz S, Pérez-Guerrero EE, Muñoz-Valle JF. J Clin Med. 2021 Dec 27; 2021 Dec 27. PMID: 35011861.
Fibroblasts positive for meflin have anti-fibrotic properties in pulmonary fibrosis.Nakahara Y, Hashimoto N, Sakamoto K, Enomoto A, Adams TS, Yokoi T, Omote N, Poli S, Ando A, Wakahara K, Suzuki A, Inoue M, Hara A, Mizutani Y, Imaizumi K, Kawabe T, Rosas IO, Takahashi M, Kaminski N, Hasegawa Y. Eur Respir J. 2021 Dec; 2021 Dec 23. PMID: 34049947.
Low IgG trough and lymphocyte subset counts are associated with hospitalization for COVID-19 in patients with primary antibody deficiency.Kuster JK, Unlu S, Makin TA, Par-Young J, Simonov M, Shafi S, Balanda M, Randolph C, Steele R, Hsu FI, Price C, Kohli-Pamnani A, Borish L, Lawrence MG, Kang I, Shin JJ. J Allergy Clin Immunol Pract. 2021 Dec 18; 2021 Dec 18. PMID: 34929372.
Distinct roles of KLF4 in mesenchymal cell subtypes during lung fibrogenesis.Chandran RR, Xie Y, Gallardo-Vara E, Adams T, Garcia-Milian R, Kabir I, Sheikh AQ, Kaminski N, Martin KA, Herzog EL, Greif DM. Nat Commun. 2021 Dec 10; 2021 Dec 10. PMID: 34893592.
Transcriptomics of bronchoalveolar lavage cells identifies new molecular endotypes of sarcoidosis.Vukmirovic M, Yan X, Gibson KF, Gulati M, Schupp JC, DeIuliis G, Adams TS, Hu B, Mihaljinec A, Woolard TN, Lynn H, Emeagwali N, Herzog EL, Chen ES, Morris A, Leader JK, Zhang Y, Garcia JGN, Maier LA, Collman RG, Drake WP, Becich MJ, Hochheiser H, Wisniewski SR, Benos PV, Moller DR, Prasse A, Koth LL, Kaminski N. Eur Respir J. 2021 Dec; 2021 Dec 2. PMID: 34083402.
Brief report: Enhanced DRα1-mMOG-35-55 treatment of severe EAE in MIF-1-deficient male mice.Vandenbark AA, Meza-Romero R, Wiedrick J, Gerstner G, Headrick A, Kent G, Seifert H, Benedek G, Bucala R, Offner H. Cell Immunol. 2021 Dec; 2021 Sep 11. PMID: 34607646.
Suppression of Plasmodium MIF-CD74 signaling protects against severe malaria.Baeza Garcia A, Siu E, Du X, Leng L, Franke-Fayard B, Janse CJ, Howland SW, Rénia L, Lolis E, Bucala R. FASEB J. 2021 Dec. PMID: 34719814.
MIF but not MIF-2 recruits inflammatory macrophages in an experimental polymicrobial sepsis model.Tilstam PV, Schulte W, Holowka T, Kim BS, Nouws J, Sauler M, Piecychna M, Pantouris G, Lolis E, Leng L, Bernhagen J, Fingerle-Rowson G, Bucala R. J Clin Invest. 2021 Dec 1. PMID: 34850744.
A Pulmonary Vascular Model From Endothelialized Whole Organ Scaffolds.Yuan Y, Leiby KL, Greaney AM, Raredon MSB, Qian H, Schupp JC, Engler AJ, Baevova P, Adams TS, Kural MH, Wang J, Obata T, Yoder MC, Kaminski N, Niklason LE. Front Bioeng Biotechnol. 2021; 2021 Nov 19. PMID: 34869270.
Case Report: Bullous Lung Disease Following COVID-19.Pednekar P, Amoah K, Homer R, Ryu C, Lutchmansingh DD. Front Med (Lausanne). 2021; 2021 Nov 17. PMID: 34869488.
Machine learning implicates the IL-18 signaling axis in severe asthma.Camiolo MJ, Zhou X, Wei Q, Trejo Bittar HE, Kaminski N, Ray A, Wenzel SE. JCI Insight. 2021 Nov 8; 2021 Nov 8. PMID: 34591794.
Correction to: COVID‑19 ARDS: a review of imaging features and overview of mechanical ventilation and its complications.Gosangi B, Rubinowitz AN, Irugu D, Gange C, Bader A, Cortopassi I. Emerg Radiol. 2021 Nov 6; 2021 Nov 6. PMID: 34741693.
Macrophage migration inhibitory factor exerts pro-proliferative and anti-apoptotic effects via CD74 in murine hepatocellular carcinoma.Wirtz TH, Saal A, Bergmann I, Fischer P, Heinrichs D, Brandt EF, Koenen MT, Djudjaj S, Schneider KM, Boor P, Bucala R, Weiskirchen R, Bernhagen J, Trautwein C, Berres ML. Br J Pharmacol. 2021 Nov; 2021 Aug 24. PMID: 34250589.
A distinct association of inflammatory molecules with outcomes of COVID-19 in younger versus older adults.Shin JJ, Jeon S, Unlu S, Par-Young J, Shin MS, Kuster JK, Afinogenova Y, Kang Y, Simonov M, Buller G, Bucala R, Kang I. Clin Immunol. 2021 Nov; 2021 Sep 22. PMID: 34560283.
Elevated murine HB-EGF confers sensitivity to diphtheria toxin in EGFR-mutant lung adenocarcinoma.Robles-Oteiza C, Ayeni D, Levy S, Homer RJ, Kaech SM, Politi K. Dis Model Mech. 2021 Nov 1; 2021 Nov 15. PMID: 34494649.
A Markov random field model for network-based differential expression analysis of single-cell RNA-seq data.Li H, Zhu B, Xu Z, Adams T, Kaminski N, Zhao H. BMC Bioinformatics. 2021 Oct 26; 2021 Oct 26. PMID: 34702190.
COVID-19 ARDS: a review of imaging features and overview of mechanical ventilation and its complications.Gosangi B, Rubinowitz AN, Irugu D, Gange C, Bader A, Cortopassi I. Emerg Radiol. 2021 Oct 26; 2021 Oct 26. PMID: 34698956.
Macrophage migration inhibitory factor drives pathology in a mouse model of spondyloarthritis and is associated with human disease.Nakamura A, Zeng F, Nakamura S, Reid KT, Gracey E, Lim M, Leng L, Jo S, Park YS, Kusuda M, Machhar R, Boroojeni SF, Wu B, Rossomacha E, Kim TH, Ciccia F, Rockel JS, Kapoor M, Inman RD, Jurisica I, Crome SQ, Bucala R, Haroon N. Sci Transl Med. 2021 Oct 20; 2021 Oct 20. PMID: 34669443.
ICBP90 Regulates MIF Expression, Glucocorticoid Sensitivity, and Apoptosis at the MIF Immune Susceptibility Locus.Yao J, Leng L, Fu W, Li J, Bronner C, Bucala R. Arthritis Rheumatol. 2021 Oct; 2021 Sep 3. PMID: 33844457.
Correction to: Abnormalities of Aspiration and Swallowing Function in Survivors of Acute Respiratory Failure.Langmore SE, Krisciunas GP, Warner H, White SD, Dvorkin D, Fink D, McNally E, Scheel R, Higgins C, Levitt JE, McKeehan J, Deane S, Siner JM, Vojnik R, Moss M. Dysphagia. 2021 Oct. PMID: 33635374.
Abnormalities of Aspiration and Swallowing Function in Survivors of Acute Respiratory Failure.Langmore SE, Krisciunas GP, Warner H, White SD, Dvorkin D, Fink D, McNally E, Scheel R, Higgins C, Levitt JE, McKeehan J, Deane S, Siner JM, Vojnik R, Moss M. Dysphagia. 2021 Oct; 2020 Nov 6. PMID: 33156398.
Mechanisms of Hypoxia-Induced Pulmonary Arterial Stiffening in Mice Revealed by a Functional Genetics Assay of Structural, Functional, and Transcriptomic Data.Manning EP, Ramachandra AB, Schupp JC, Cavinato C, Raredon MSB, Bärnthaler T, Cosme C Jr, Singh I, Tellides G, Kaminski N, Humphrey JD. Front Physiol. 2021; 2021 Sep 14. PMID: 34594238.
Intravesical CD74 and CXCR4, macrophage migration inhibitory factor (MIF) receptors, mediate bladder pain.Ye S, Ma F, Mahmood DFD, Meyer-Siegler KL, Menard RE, Hunt DE, Leng L, Bucala R, Vera PL. PLoS One. 2021; 2021 Aug 23. PMID: 34424927.
Integrated computational and experimental pipeline for quantifying local cell-matrix interactions.Xiao H, Nguyen RY, LaRanger R, Herzog EL, Mak M. Sci Rep. 2021 Aug 12; 2021 Aug 12. PMID: 34385554.
Evolving Perspectives on Innate Immune Mechanisms of IPF.Ishikawa G, Liu A, Herzog EL. Front Mol Biosci. 2021; 2021 Aug 9. PMID: 34434962.
Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets.Reichmann MT, Tezera LB, Vallejo AF, Vukmirovic M, Xiao R, Reynolds J, Jogai S, Wilson S, Marshall B, Jones MG, Leslie A, D'Armiento JM, Kaminski N, Polak ME, Elkington P. J Clin Invest. 2021 Aug 2. PMID: 34128839.
Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung.Schupp JC, Adams TS, Cosme C Jr, Raredon MSB, Yuan Y, Omote N, Poli S, Chioccioli M, Rose KA, Manning EP, Sauler M, DeIuliis G, Ahangari F, Neumark N, Habermann AC, Gutierrez AJ, Bui LT, Lafyatis R, Pierce RW, Meyer KB, Nawijn MC, Teichmann SA, Banovich NE, Kropski JA, Niklason LE, Pe'er D, Yan X, Homer RJ, Rosas IO, Kaminski N. Circulation. 2021 Jul 27; 2021 May 25. PMID: 34030460.
Fibroblasts: Origins, definitions, and functions in health and disease.Plikus MV, Wang X, Sinha S, Forte E, Thompson SM, Herzog EL, Driskell RR, Rosenthal N, Biernaskie J, Horsley V. Cell. 2021 Jul 22. PMID: 34297930.
Defective Early B Cell Tolerance Checkpoints in Patients With Systemic Sclerosis Allow the Production of Self Antigen-Specific Clones.Glauzy S, Olson B, May CK, Parisi D, Massad C, Hansen JE, Ryu C, Herzog EL, Meffre E. Arthritis Rheumatol. 2021 Jul 19; 2021 Jul 19. PMID: 34279059.
Blood Transcriptomics Predicts Progression of Pulmonary Fibrosis and Associated Natural Killer Cells.Huang Y, Oldham JM, Ma SF, Unterman A, Liao SY, Barros AJ, Bonham CA, Kim JS, Vij R, Adegunsoye A, Strek ME, Molyneaux PL, Maher TM, Herazo-Maya JD, Kaminski N, Moore BB, Martinez FJ, Noth I. Am J Respir Crit Care Med. 2021 Jul 15. PMID: 33689671.
Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity.Bui LT, Winters NI, Chung MI, Joseph C, Gutierrez AJ, Habermann AC, Adams TS, Schupp JC, Poli S, Peter LM, Taylor CJ, Blackburn JB, Richmond BW, Nicholson AG, Rassl D, Wallace WA, Rosas IO, Jenkins RG, Kaminski N, Kropski JA, Banovich NE. Nat Commun. 2021 Jul 14; 2021 Jul 14. PMID: 34262047.
Antibodies against human endogenous retrovirus K102 envelope activate neutrophils in systemic lupus erythematosus.Tokuyama M, Gunn BM, Venkataraman A, Kong Y, Kang I, Rakib T, Townsend MJ, Costenbader KH, Alter G, Iwasaki A. J Exp Med. 2021 Jul 5; 2021 May 21. PMID: 34019642.
Nucleotide-binding domain and leucine-rich-repeat-containing protein X1 deficiency induces nicotinamide adenine dinucleotide decline, mechanistic target of rapamycin activation, and cellular senescence and accelerates aging lung-like changes.Shin HJ, Kim SH, Park HJ, Shin MS, Kang I, Kang MJ. Aging Cell. 2021 Jul; 2021 Jun 4. PMID: 34087956.
Genetic Determinants of EGFR-Driven Lung Cancer Growth and Therapeutic Response In Vivo.Foggetti G, Li C, Cai H, Hellyer JA, Lin WY, Ayeni D, Hastings K, Choi J, Wurtz A, Andrejka L, Maghini DG, Rashleigh N, Levy S, Homer R, Gettinger SN, Diehn M, Wakelee HA, Petrov DA, Winslow MM, Politi K. Cancer Discov. 2021 Jul; 2021 Mar 11. PMID: 33707235.
Effectiveness of Thermal Ablation and Stereotactic Radiotherapy Based on Stage I Lung Cancer Histology.Uhlig J, Mehta S, Case MD, Dhanasopon A, Blasberg J, Homer RJ, Solomon SB, Kim HS. J Vasc Interv Radiol. 2021 Jul; 2021 Mar 31. PMID: 33811997.
Effector Memory CD8⁺ and CD4⁺ T Cell Immunity Associated with Metabolic Syndrome in Obese Children.Yang DH, Lee H, Lee N, Shin MS, Kang I, Kang KS. Pediatr Gastroenterol Hepatol Nutr. 2021 Jul; 2021 Jul 5. PMID: 34316472.
Cutting Edge: Distinct B Cell Repertoires Characterize Patients with Mild and Severe COVID-19.Hoehn KB, Ramanathan P, Unterman A, Sumida TS, Asashima H, Hafler DA, Kaminski N, Dela Cruz CS, Sealfon SC, Bukreyev A, Kleinstein SH. J Immunol. 2021 Jun 15; 2021 May 28. PMID: 34049971.
Role of MIF in coordinated expression of hepatic chemokines in patients with alcohol-associated hepatitis.Poulsen KL, Fan X, Kibler CD, Huang E, Wu X, McMullen MR, Leng L, Bucala R, Ventura-Cots M, Argemi J, Bataller R, Nagy LE. JCI Insight. 2021 Jun 8; 2021 Jun 8. PMID: 33945507.
Elevated IL-15 concentrations in the sarcoidosis lung are independent of granuloma burden and disease phenotypes.Minasyan M, Sharma L, Pivarnik T, Liu W, Adams T, Bermejo S, Peng X, Liu A, Ishikawa G, Perry C, Kaminski N, Gulati M, Herzog EL, Dela Cruz CS, Ryu C. Am J Physiol Lung Cell Mol Physiol. 2021 Jun 1; 2021 Apr 14. PMID: 33851886.
PINK1 mediates the protective effects of thyroid hormone T3 in hyperoxia-induced lung injury.Zhang Y, Yu G, Kaminski N, Lee PJ. Am J Physiol Lung Cell Mol Physiol. 2021 Jun 1; 2021 Apr 14. PMID: 33851544.
Reliability of histopathologic diagnosis of fibrotic interstitial lung disease: an international collaborative standardization project.Camp R, Smith ML, Larsen BT, Roden AC, Farver C, Moreira AL, Attanoos R, Pillappa R, Sansano I, Fabro AT, Homer RJ. BMC Pulm Med. 2021 Jun 1; 2021 Jun 1. PMID: 34074264.
Molecular Markers and the Promise of Precision Medicine for Interstitial Lung Disease.Newton CA, Herzog EL. Clin Chest Med. 2021 Jun. PMID: 34024410.
Cathepsin B promotes collagen biosynthesis, which drives bronchiolitis obliterans syndrome.Morrone C, Smirnova NF, Jeridi A, Kneidinger N, Hollauer C, Schupp JC, Kaminski N, Jenne D, Eickelberg O, Yildirim AÖ. Eur Respir J. 2021 May; 2021 May 13. PMID: 33303550.
Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children.Ramaswamy A, Brodsky NN, Sumida TS, Comi M, Asashima H, Hoehn KB, Li N, Liu Y, Shah A, Ravindra NG, Bishai J, Khan A, Lau W, Sellers B, Bansal N, Guerrerio P, Unterman A, Habet V, Rice AJ, Catanzaro J, Chandnani H, Lopez M, Kaminski N, Dela Cruz CS, Tsang JS, Wang Z, Yan X, Kleinstein SH, van Dijk D, Pierce RW, Hafler DA, Lucas CL. Immunity. 2021 May 11; 2021 Apr 13. PMID: 33891889.
17-a-estradiol late in life extends lifespan in aging UM-HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex.Harrison DE, Strong R, Reifsnyder P, Kumar N, Fernandez E, Flurkey K, Javors MA, Lopez-Cruzan M, Macchiarini F, Nelson JF, Bitto A, Sindler AL, Cortopassi G, Kavanagh K, Leng L, Bucala R, Rosenthal N, Salmon A, Stearns TM, Bogue M, Miller RA. Aging Cell. 2021 May; 2021 Mar 31. PMID: 33788371.
The Reply.Bader AS, Rubinowitz AN, Gange CP Jr, Bader EM, Cortopassi IO. Am J Med. 2021 May. PMID: 33962714.
Initial Evaluation of Rapid, Direct-to-Digital Prostate Biopsy Pathology.Torres R, Olson E, Homer R, Martin DT, Levene MJ, Perincheri S, Sprenkle PC, Humphrey PA. Arch Pathol Lab Med. 2021 May 1. PMID: 32991670.
An 84-Year-Old Physician With Progressive Dyspnea and Bilateral Upper Lobe Opacities.Harris ZM, Antin-Ozerkis D. Chest. 2021 May. PMID: 33965157.
Response.Price CC, Altice FL, Azar MM, McManus D, Gleeson SE, Britto CJ, Azmy V, Kaman K, Davis M, Chupp G, Bucala R, Kaminski N, Topal JE, Dela Cruz C, Malinis M. Chest. 2021 May. PMID: 33965143.
Infectious Complications Predict Premature CD8⁺ T-cell Senescence in CD40 Ligand-Deficient Patients.Shin JJ, Catanzaro J, Yonkof JR, Delmonte O, Sacco K, Shin MS, Reddy S, Whittington PJ, Soffer G, Mustillo PJ, Sullivan KE, Notarangelo LD, Abraham RS, Romberg N, Kang I. J Clin Immunol. 2021 May; 2021 Jan 26. PMID: 33495902.
Non-steroidal treatment of cardiac sarcoidosis: A systematic review.Gallegos C, Oikonomou EK, Grimshaw A, Gulati M, Young BD, Miller EJ. Int J Cardiol Heart Vasc. 2021 Jun; 2021 Apr 29. PMID: 33997256.
Mitochondrial antiviral signaling protein is crucial for the development of pulmonary fibrosis.Kim SH, Lee JY, Yoon CM, Shin HJ, Lee SW, Rosas I, Herzog E, Dela Cruz CS, Kaminski N, Kang MJ. Eur Respir J. 2021 Apr; 2021 Apr 15. PMID: 33093124.
Intermediate-dose anticoagulation, aspirin, and in-hospital mortality in COVID-19: A propensity score-matched analysis.Meizlish ML, Goshua G, Liu Y, Fine R, Amin K, Chang E, DeFilippo N, Keating C, Liu Y, Mankbadi M, McManus D, Wang SY, Price C, Bona RD, Ochoa Chaar CI, Chun HJ, Pine AB, Rinder HM, Siner JM, Neuberg DS, Owusu KA, Lee AI. Am J Hematol. 2021 Apr 1; 2021 Feb 22. PMID: 33476420.
COVID-19 as an occupational disease.Carlsten C, Gulati M, Hines S, Rose C, Scott K, Tarlo SM, Torén K, Sood A, de la Hoz RE. Am J Ind Med. 2021 Apr; 2021 Jan 24. PMID: 33491195.
Elevated plasma level of Pentraxin 3 is associated with emphysema and mortality in smokers.Zhang Y, Tedrow J, Nouraie M, Li X, Chandra D, Bon J, Kass DJ, Fuhrman CR, Leader JK, Duncan SR, Kaminski N, Sciurba FC. Thorax. 2021 Apr; 2021 Jan 21. PMID: 33479043.
Clinical characteristics and outcomes for 7,995 patients with SARS-CoV-2 infection.McPadden J, Warner F, Young HP, Hurley NC, Pulk RA, Singh A, Durant TJS, Gong G, Desai N, Haimovich A, Taylor RA, Gunel M, Dela Cruz CS, Farhadian SF, Siner J, Villanueva M, Churchwell K, Hsiao A, Torre CJ Jr, Velazquez EJ, Herbst RS, Iwasaki A, Ko AI, Mortazavi BJ, Krumholz HM, Schulz WL. PLoS One. 2021; 2021 Mar 31. PMID: 33788846.
Delphi Consensus Recommendations on Management of Dosing, Adverse Events, and Comorbidities in the Treatment of Idiopathic Pulmonary Fibrosis with Nintedanib.Rahaghi F, Belperio JA, Fitzgerald J, Gulati M, Hallowell R, Highland KB, Huie TJ, Kim HJ, Kolb M, Lasky JA, Southern BD, Swigris JJ, de Andrade JA. Clin Med Insights Circ Respir Pulm Med. 2021; 2021 Mar 30. PMID: 33854398.
Co-inhibitor expression on tumor infiltrating and splenic lymphocytes after dual checkpoint inhibition in a microsatellite stable model of colorectal cancer.Slovak RJ, Park HJ, Kamp WM, Ludwig JM, Kang I, Kim HS. Sci Rep. 2021 Mar 26; 2021 Mar 26. PMID: 33772035.
Macrophage-derived PDGF-B induces muscularization in murine and human pulmonary hypertension.Ntokou A, Dave JM, Kauffman AC, Sauler M, Ryu C, Hwa J, Herzog EL, Singh I, Saltzman WM, Greif DM. JCI Insight. 2021 Mar 22; 2021 Mar 22. PMID: 33591958.
CD74 is a regulator of hematopoietic stem cell maintenance.Becker-Herman S, Rozenberg M, Hillel-Karniel C, Gil-Yarom N, Kramer MP, Barak A, Sever L, David K, Radomir L, Lewinsky H, Levi M, Friedlander G, Bucala R, Peled A, Shachar I. PLoS Biol. 2021 Mar; 2021 Mar 4. PMID: 33661886.
A Clinic Blueprint for Post-Coronavirus Disease 2019 RECOVERY: Learning From the Past, Looking to the Future.Lutchmansingh DD, Knauert MP, Antin-Ozerkis DE, Chupp G, Cohn L, Dela Cruz CS, Ferrante LE, Herzog EL, Koff J, Rochester CL, Ryu C, Singh I, Tickoo M, Winks V, Gulati M, Possick JD. Chest. 2021 Mar; 2020 Nov 4. PMID: 33159907.
Genetic analyses identify GSDMB associated with asthma severity, exacerbations, and antiviral pathways.Li X, Christenson SA, Modena B, Li H, Busse WW, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Hastie AT, Israel E, Jarjour NN, Levy BD, Moore WC, Woodruff PG, Kaminski N, Wenzel SE, Bleecker ER, Meyers DA. J Allergy Clin Immunol. 2021 Mar; 2020 Aug 11. PMID: 32795586.
Extracellular MIF, but not its homologue D-DT, promotes fibroblast motility independently of its receptor complex CD74/CD44.Szczęśniak P, Henke T, Fröhlich S, Plessmann U, Urlaub H, Leng L, Bucala R, Grosse R, Meinhardt A, Klug J. J Cell Sci. 2021 Feb 10; 2021 Feb 10. PMID: 33328325.
Hsp90-stabilized MIF supports tumor progression via macrophage recruitment and angiogenesis in colorectal cancer.Klemke L, De Oliveira T, Witt D, Winkler N, Bohnenberger H, Bucala R, Conradi LC, Schulz-Heddergott R. Cell Death Dis. 2021 Feb 4; 2021 Feb 4. PMID: 33542244.
Long noncoding RNA TINCR is a novel regulator of human bronchial epithelial cell differentiation state.Omote N, Sakamoto K, Li Q, Schupp JC, Adams T, Ahangari F, Chioccioli M, DeIuliis G, Hashimoto N, Hasegawa Y, Kaminski N. Physiol Rep. 2021 Feb. PMID: 33527707.
Gene coexpression networks reveal novel molecular endotypes in alpha-1 antitrypsin deficiency.Chu JH, Zang W, Vukmirovic M, Yan X, Adams T, DeIuliis G, Hu B, Mihaljinec A, Schupp JC, Becich MJ, Hochheiser H, Gibson KF, Chen ES, Morris A, Leader JK, Wisniewski SR, Zhang Y, Sciurba FC, Collman RG, Sandhaus R, Herzog EL, Patterson KC, Sauler M, Strange C, Kaminski N. Thorax. 2021 Feb; 2020 Dec 10. PMID: 33303696.
Unexpected Pro-Fibrotic Effect of MIF in Non-Alcoholic Steatohepatitis Is Linked to a Shift in NKT Cell Populations.Heinrichs D, Brandt EF, Fischer P, Köhncke J, Wirtz TH, Guldiken N, Djudjaj S, Boor P, Kroy D, Weiskirchen R, Bucala R, Wasmuth HE, Strnad P, Trautwein C, Bernhagen J, Berres ML. Cells. 2021 Jan 28; 2021 Jan 28. PMID: 33525493.
MicroRNA miR-24-3p reduces DNA damage responses, apoptosis, and susceptibility to chronic obstructive pulmonary disease.Nouws J, Wan F, Finnemore E, Roque W, Kim SJ, Bazan I, Li CX, Skold CM, Dai Q, Yan X, Chioccioli M, Neumeister V, Britto CJ, Sweasy J, Bindra R, Wheelock ÅM, Gomez JL, Kaminski N, Lee PJ, Sauler M. JCI Insight. 2021 Jan 25; 2021 Jan 25. PMID: 33290275.
Intermediate-dose anticoagulation, aspirin, and in-hospital mortality in COVID-19: a propensity score-matched analysis.Meizlish ML, Goshua G, Liu Y, Fine R, Amin K, Chang E, DeFilippo N, Keating C, Liu Y, Mankbadi M, McManus D, Wang S, Price C, Bona RD, Chaar CIO, Chun HJ, Pine AB, Rinder HM, Siner J, Neuberg DS, Owusu KA, Lee AI. medRxiv. 2021 Jan 15; 2021 Jan 15. PMID: 33469595.
Lung-Protective Ventilation Over 6 Years at a Large Academic Medical Center: An Evaluation of Trends, Adherence, and Perceptions of Benefit.Gao CA, Howard FM, Siner JM, Candido TD, Ferrante LE. Crit Care Explor. 2021 Jan; 2021 Jan 8. PMID: 33458691.
Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity.Bui LT, Winters NI, Chung MI, Joseph C, Gutierrez AJ, Habermann AC, Adams TS, Schupp JC, Poli S, Peter LM, Taylor CJ, Blackburn JB, Richmond BW, Nicholson AG, Rassl D, Wallace WA, Rosas IO, Jenkins RG, Kaminski N, Kropski JA, Banovich NE. bioRxiv. 2021 Jan 4; 2021 Jan 4. PMID: 33106805.
Macrophage-derived netrin-1 drives adrenergic nerve-associated lung fibrosis.Gao R, Peng X, Perry C, Sun H, Ntokou A, Ryu C, Gomez JL, Reeves BC, Walia A, Kaminski N, Neumark N, Ishikawa G, Black KE, Hariri LP, Moore MW, Gulati M, Homer RJ, Greif DM, Eltzschig HK, Herzog EL. J Clin Invest. 2021 Jan 4. PMID: 33393489.
Genetic determinants of ammonia-induced acute lung injury in mice.Bein K, Ganguly K, Martin TM, Concel VJ, Brant KA, Di YPP, Upadhyay S, Fabisiak JP, Vuga LJ, Kaminski N, Kostem E, Eskin E, Prows DR, Jang AS, Leikauf GD. Am J Physiol Lung Cell Mol Physiol. 2021 Jan 1; 2020 Oct 14. PMID: 33050709.
Expression of macrophage migration inhibitory factor and its receptor CD74 in systemic sclerosis.Baños-Hernández CJ, Bucala R, Hernández-Bello J, Navarro-Zarza JE, Villanueva-Pérez MA, Godínez-Rubí M, Parra-Rojas I, Vázquez-Villamar M, Pereira-Suárez AL, Muñoz Valle JF. Cent Eur J Immunol. 2021; 2021 Oct 8. PMID: 34764810.
Corrigendum to "Haploinsufficiency of multiple del(5q) genes induce B cell abnormalities in mice" [Leuk. Res. 96C (2020) 106428].Liu T, Ahmed T, Krysiak K, Shirai CL, Shao J, Nunley R, Bucala R, McKenzie A, Ndonwi M, Walter MJ. Leuk Res. 2021 Jan; 2020 Dec 4. PMID: 33288274.
Balance between macrophage migration inhibitory factor and sCD74 predicts outcome in patients with acute decompensation of cirrhosis.Wirtz TH, Reuken PA, Jansen C, Fischer P, Bergmann I, Backhaus C, Emontzpohl C, Reißing J, Brandt EF, Koenen MT, Schneider KM, Schierwagen R, Brol MJ, Chang J, Zimmermann HW, Köse-Vogel N, Eggermann T, Kurth I, Stoppe C, Bucala R, Bernhagen J, Praktiknjo M, Stallmach A, Trautwein C, Trebicka J, Bruns T, Berres ML. JHEP Rep. 2021 Apr; 2020 Dec 17. PMID: 33659891.

2020

Toward a Cell Atlas of the Human Airway.Schupp JC, Yan X, Kaminski N. Am J Respir Crit Care Med. 2020 Dec 15. PMID: 32841575.
Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling.Israelow B, Song E, Mao T, Lu P, Meir A, Liu F, Alfajaro MM, Wei J, Dong H, Homer RJ, Ring A, Wilen CB, Iwasaki A. J Exp Med. 2020 Dec 7. PMID: 32750141.
The Idiopathic Pulmonary Fibrosis Cell Atlas.Neumark N, Cosme C Jr, Rose KA, Kaminski N. Am J Physiol Lung Cell Mol Physiol. 2020 Dec 1; 2020 Sep 30. PMID: 32996785.
The Pulmonary Fibrosis Foundation Patient Registry. Rationale, Design, and Methods.Wang BR, Edwards R, Freiheit EA, Ma Y, Burg C, de Andrade J, Lancaster L, Lindell K, Nathan SD, Raghu G, Gibson K, Gulati M, Mason W, Noth I, Schmidt B, Spino C, Staszak S, Stauffer J, Wolters PJ, Cosgrove GP, Flaherty KR. Ann Am Thorac Soc. 2020 Dec. PMID: 32776789.
IL-7Rα^low CD8⁺ T Cells from Healthy Individuals Are Anergic with Defective Glycolysis.Sim JH, Kim JH, Park AK, Lee J, Kim KM, Shin HM, Kim M, Choi K, Choi EY, Kang I, Lee DS, Kim HR. J Immunol. 2020 Dec 1; 2020 Oct 26. PMID: 33106337.
Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis.Jiang R, Hoehn KB, Lee CS, Pham MC, Homer RJ, Detterbeck FC, Aban I, Jacobson L, Vincent A, Nowak RJ, Kaminski HJ, Kleinstein SH, O'Connor KC. Proc Natl Acad Sci U S A. 2020 Dec 1; 2020 Nov 16. PMID: 33199596.
Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting.Kontos C, El Bounkari O, Krammer C, Sinitski D, Hille K, Zan C, Yan G, Wang S, Gao Y, Brandhofer M, Megens RTA, Hoffmann A, Pauli J, Asare Y, Gerra S, Bourilhon P, Leng L, Eckstein HH, Kempf WE, Pelisek J, Gokce O, Maegdefessel L, Bucala R, Dichgans M, Weber C, Kapurniotu A, Bernhagen J. Nat Commun. 2020 Nov 25; 2020 Nov 25. PMID: 33239628.
Single-Cell Transcriptional Archetypes of Airway Inflammation in Cystic Fibrosis.Schupp JC, Khanal S, Gomez JL, Sauler M, Adams TS, Chupp GL, Yan X, Poli S, Zhao Y, Montgomery RR, Rosas IO, Dela Cruz CS, Bruscia EM, Egan ME, Kaminski N, Britto CJ. Am J Respir Crit Care Med. 2020 Nov 15. PMID: 32603604.
Social Distancing with Portable Chest Radiographs During the COVID-19 Pandemic: Assessment of Radiograph Technique and Image Quality Obtained at 6 Feet and Through Glass.Gange CP, Pahade JK, Cortopassi I, Bader AS, Bokhari J, Hoerner M, Thomas KM, Rubinowitz AN. Radiol Cardiothorac Imaging. 2020 Dec; 2020 Nov 12. PMID: 33778645.
Clinical Characteristics and Outcomes for 7,995 Patients with SARS-CoV-2 Infection.McPadden J, Warner F, Young HP, Hurley NC, Pulk RA, Singh A, Durant TJ, Gong G, Desai N, Haimovich A, Taylor RA, Gunel M, Cruz CSD, Farhadian SF, Siner J, Villanueva M, Churchwell K, Hsiao A, Torre CJ Jr, Velazquez EJ, Herbst RS, Iwasaki A, Ko AI, Mortazavi BJ, Krumholz HM, Schulz WL. medRxiv. 2020 Nov 8; 2020 Nov 8. PMID: 32743602.
Ventilator Sharing Using Volume-controlled Ventilation during the COVID-19 Pandemic.Milner A, Siner JM, Balcezak T, Fajardo E. Am J Respir Crit Care Med. 2020 Nov 1. PMID: 32744456.
The "Infodemic" of COVID-19.Solomon DH, Bucala R, Kaplan MJ, Nigrovic PA. Arthritis Rheumatol. 2020 Nov; 2020 Sep 22. PMID: 32741134.
Bioactive Plasma Mitochondrial DNA Is Associated With Disease Progression in Scleroderma-Associated Interstitial Lung Disease.Ryu C, Walia A, Ortiz V, Perry C, Woo S, Reeves BC, Sun H, Winkler J, Kanyo JE, Wang W, Vukmirovic M, Ristic N, Stratton EA, Meena SR, Minasyan M, Kurbanov D, Liu X, Lam TT, Farina G, Gomez JL, Gulati M, Herzog EL. Arthritis Rheumatol. 2020 Nov; 2020 Oct 8. PMID: 32602227.
Development of an Accurate Bedside Swallowing Evaluation Decision Tree Algorithm for Detecting Aspiration in Acute Respiratory Failure Survivors.Moss M, White SD, Warner H, Dvorkin D, Fink D, Gomez-Taborda S, Higgins C, Krisciunas GP, Levitt JE, McKeehan J, McNally E, Rubio A, Scheel R, Siner JM, Vojnik R, Langmore SE. Chest. 2020 Nov; 2020 Jul 25. PMID: 32721404.
Attenuated Novel SARS Coronavirus 2 Infection in an Allogeneic Hematopoietic Stem Cell Transplant Patient on Ruxolitinib.Foss FM, Rubinowitz A, Landry ML, Isufi I, Gowda L, Seropian S, Perreault S, Shenoi SV. Clin Lymphoma Myeloma Leuk. 2020 Nov; 2020 Jun 25. PMID: 32727701.
The Association Between Endotracheal Tube Size and Aspiration (During Flexible Endoscopic Evaluation of Swallowing) in Acute Respiratory Failure Survivors.Krisciunas GP, Langmore SE, Gomez-Taborda S, Fink D, Levitt JE, McKeehan J, McNally E, Scheel R, Rubio AC, Siner JM, Vojnik R, Warner H, White SD, Moss M. Crit Care Med. 2020 Nov. PMID: 32804785.
Diagnosis of SARS-CoV-2 infection in the setting of the cytokine release syndrome.Azar MM, Shin JJ, Kang I, Landry M. Expert Rev Mol Diagn. 2020 Nov; 2020 Oct 12. PMID: 32990479.
Reduced development of COVID-19 in children reveals molecular checkpoints gating pathogenesis illuminating potential therapeutics.Steinman JB, Lum FM, Ho PP, Kaminski N, Steinman L. Proc Natl Acad Sci U S A. 2020 Oct 6; 2020 Sep 3. PMID: 32883878.
Imaging in the Evaluation of Chest Pain in the Primary Care Setting, Part 2: Sources of Noncardiac Chest Pain.Bader AS, Rubinowitz AN, Gange CP Jr, Bader EM, Cortopassi IO. Am J Med. 2020 Oct; 2020 May 20. PMID: 32442508.
Tocilizumab Treatment for Cytokine Release Syndrome in Hospitalized Patients With Coronavirus Disease 2019: Survival and Clinical Outcomes.Price CC, Altice FL, Shyr Y, Koff A, Pischel L, Goshua G, Azar MM, Mcmanus D, Chen SC, Gleeson SE, Britto CJ, Azmy V, Kaman K, Gaston DC, Davis M, Burrello T, Harris Z, Villanueva MS, Aoun-Barakat L, Kang I, Seropian S, Chupp G, Bucala R, Kaminski N, Lee AI, LoRusso PM, Topal JE, Dela Cruz C, Malinis M. Chest. 2020 Oct; 2020 Jun 15. PMID: 32553536.
The Macrophage Migration Inhibitory Factor (MIF) Promoter Polymorphisms (rs3063368, rs755622) Predict Acute Kidney Injury and Death after Cardiac Surgery.Averdunk L, Bernhagen J, Fehnle K, Surowy H, Lüdecke HJ, Mucha S, Meybohm P, Wieczorek D, Leng L, Marx G, Leaf DE, Zarbock A, Zacharowski K, On Behalf Of The RIPHeart Study Collaborators, Bucala R, Stoppe C. J Clin Med. 2020 Sep 11; 2020 Sep 11. PMID: 32932965.