ILD Publications

2023

TLR9 ligand sequestration by chemokine CXCL4 negatively affects central B cell tolerance.Çakan E, Ah Kioon MD, Garcia-Carmona Y, Glauzy S, Oliver D, Yamakawa N, Vega Loza A, Du Y, Schickel JN, Boeckers JM, Yang C, Baldo A, Ivashkiv LB, Young RM, Staudt LM, Moody KL, Nündel K, Marshak-Rothstein A, van der Made CI, Hoischen A, Hayward A, Rossato M, Radstake TRDJ, Cunningham-Rundles C, Ryu C, Herzog EL, Barrat FJ, Meffre E. J Exp Med. 2023 Dec 4; 2023 Sep 29. PMID: 37773045.
Cardiothoracic complications of immune checkpoint inhibitors.Gosangi B, Wang Y, Rubinowitz AN, Kwan J, Traube L, Gange C, Bader AS. Clin Imaging. 2023 Oct; 2023 Aug 9. PMID: 37659356.
Alveolar Vascular Remodeling in Nonspecific Interstitial Pneumonia: Replacement of Normal Lung Capillaries with COL15A1-Positive Endothelial Cells.Schupp JC, Manning EP, Chioccioli M, Kamp JC, Christian L, Ryu C, Herzog E, Kühnel MP, Prasse A, Kaminski N, Jonigk DD, Homer RJ. Am J Respir Crit Care Med. 2023 Oct 1. PMID: 37552025.
Genetic analyses of chr11p15.5 region identify MUC5AC-MUC5B associated with asthma-related phenotypes.Li X, Li H, Christenson SA, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston BM, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Zein J, Kaminski N, Wenzel SE, Woodruff PG, Bleecker ER, Meyers DA. J Asthma. 2023 Oct; 2023 Apr 21. PMID: 36946148.
Distinguishing features of Long COVID identified through immune profiling.Klein J, Wood J, Jaycox J, Dhodapkar RM, Lu P, Gehlhausen JR, Tabachnikova A, Greene K, Tabacof L, Malik AA, Silva Monteiro V, Silva J, Kamath K, Zhang M, Dhal A, Ott IM, Valle G, Peña-Hernandez M, Mao T, Bhattacharjee B, Takahashi T, Lucas C, Song E, Mccarthy D, Breyman E, Tosto-Mancuso J, Dai Y, Perotti E, Akduman K, Tzeng TJ, Xu L, Geraghty AC, Monje M, Yildirim I, Shon J, Medzhitov R, Lutchmansingh D, Possick JD, Kaminski N, Omer SB, Krumholz HM, Guan L, Dela Cruz CS, van Dijk D, Ring AM, Putrino D, Iwasaki A. Nature. 2023 Sep 25; 2023 Sep 25. PMID: 37748514.
SRC and TKS5 mediated podosome formation in fibroblasts promotes extracellular matrix invasion and pulmonary fibrosis.Barbayianni I, Kanellopoulou P, Fanidis D, Nastos D, Ntouskou ED, Galaris A, Harokopos V, Hatzis P, Tsitoura E, Homer R, Kaminski N, Antoniou KM, Crestani B, Tzouvelekis A, Aidinis V. Nat Commun. 2023 Sep 21; 2023 Sep 21. PMID: 37735172.
When Development of the Alveolar Gas Exchange Unit Fails: Universal Single-Cell Lessons from Rare Monogenic Disorders.Schupp JC, Kaminski N. Am J Respir Crit Care Med. 2023 Sep 15. PMID: 37555730.
Immunology for the Rheumatologist: A&R introduces a new problem-based immunology review series with great educational potential.Bucala R, Solomon DH. Arthritis Rheumatol. 2023 Sep 1; 2023 Sep 1. PMID: 37655656.
An AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model.Charkoftaki G, Aalizadeh R, Santos-Neto A, Tan WY, Davidson EA, Nikolopoulou V, Wang Y, Thompson B, Furnary T, Chen Y, Wunder EA, Coppi A, Schulz W, Iwasaki A, Pierce RW, Cruz CSD, Desir GV, Kaminski N, Farhadian S, Veselkov K, Datta R, Campbell M, Thomaidis NS, Ko AI, Thompson DC, Vasiliou V. Hum Genomics. 2023 Aug 29; 2023 Aug 29. PMID: 37641126.
Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation.Pekayvaz K, Gold C, Hoseinpour P, Engel A, Martinez-Navarro A, Eivers L, Coletti R, Joppich M, Dionísio F, Kaiser R, Tomas L, Janjic A, Knott M, Mehari F, Polewka V, Kirschner M, Boda A, Nicolai L, Schulz H, Titova A, Kilani B, Lorenz M, Fingerle-Rowson G, Bucala R, Enard W, Zimmer R, Weber C, Libby P, Schulz C, Massberg S, Stark K. Immunity. 2023 Aug 24; 2023 Aug 24. PMID: 37652021.
iDESC: identifying differential expression in single-cell RNA sequencing data with multiple subjects.Liu Y, Zhao J, Adams TS, Wang N, Schupp JC, Wu W, McDonough JE, Chupp GL, Kaminski N, Wang Z, Yan X. BMC Bioinformatics. 2023 Aug 22; 2023 Aug 22. PMID: 37608264.
Polymer nanoparticles deliver mRNA to the lung for mucosal vaccination.Suberi A, Grun MK, Mao T, Israelow B, Reschke M, Grundler J, Akhtar L, Lee T, Shin K, Piotrowski-Daspit AS, Homer RJ, Iwasaki A, Suh HW, Saltzman WM. Sci Transl Med. 2023 Aug 16; 2023 Aug 16. PMID: 37585505.
Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer.de Miguel FJ, Gentile C, Feng WW, Silva SJ, Sankar A, Exposito F, Cai WL, Melnick MA, Robles-Oteiza C, Hinkley MM, Tsai JA, Hartley AV, Wei J, Wurtz A, Li F, Toki MI, Rimm DL, Homer R, Wilen CB, Xiao AZ, Qi J, Yan Q, Nguyen DX, Jänne PA, Kadoch C, Politi KA. Cancer Cell. 2023 Aug 14; 2023 Aug 3. PMID: 37541244.
Integrative genetic and genomic networks identify microRNA associated with COPD and ILD.Pavel AB, Garrison C, Luo L, Liu G, Taub D, Xiao J, Juan-Guardela B, Tedrow J, Alekseyev YO, Yang IV, Geraci MW, Sciurba F, Schwartz DA, Kaminski N, Beane J, Spira A, Lenburg ME, Campbell JD. Sci Rep. 2023 Aug 11; 2023 Aug 11. PMID: 37567908.
Integrative analyses for the identification of idiopathic pulmonary fibrosis-associated genes and shared loci with other diseases.Chen M, Zhang Y, Adams T, Ji D, Jiang W, Wain LV, Cho M, Kaminski N, Zhao H. Thorax. 2023 Aug; 2022 Oct 10. PMID: 36216496.
A statistical framework to identify cell types whose genetically regulated proportions are associated with complex diseases.Liu W, Deng W, Chen M, Dong Z, Zhu B, Yu Z, Tang D, Sauler M, Lin C, Wain LV, Cho MH, Kaminski N, Zhao H. PLoS Genet. 2023 Jul; 2023 Jul 31. PMID: 37523391.
COVID-19 annual update: a narrative review.Biancolella M, Colona VL, Luzzatto L, Watt JL, Mattiuz G, Conticello SG, Kaminski N, Mehrian-Shai R, Ko AI, Gonsalves GS, Vasiliou V, Novelli G, Reichardt JKV. Hum Genomics. 2023 Jul 24; 2023 Jul 24. PMID: 37488607.
Macrophage migration inhibitory factor (MIF) and its homolog D-dopachrome tautomerase (D-DT) are significant promotors of UVB- but not chemically induced non-melanoma skin cancer.Huth S, Huth L, Heise R, Marquardt Y, Lopopolo L, Piecychna M, Boor P, Fingerle-Rowson G, Kapurniotu A, Yazdi AS, Bucala R, Bernhagen J, Baron JM. Sci Rep. 2023 Jul 18; 2023 Jul 18. PMID: 37464010.
The MIF promoter SNP rs755622 is associated with immune activation in glioblastoma.Alban TJ, Grabowski MM, Otvos B, Bayik D, Wang W, Zalavadia A, Makarov V, Troike K, McGraw M, Rabljenovic A, Lauko A, Neumann C, Roversi G, Waite KA, Cioffi G, Patil N, Tran TT, McCortney K, Steffens A, Diaz CM, Brown JM, Egan KM, Horbinski CM, Barnholtz-Sloan JS, Rajappa P, Vogelbaum MA, Bucala R, Chan TA, Ahluwalia MS, Lathia JD. JCI Insight. 2023 Jul 10; 2023 Jul 10. PMID: 37252795.
VISTA (PD-1H) Is a Crucial Immune Regulator to Limit Pulmonary Fibrosis.Kim SH, Adams TS, Hu Q, Shin HJ, Chae G, Lee SE, Sharma L, Kwon HK, Lee FY, Park HJ, Huh WJ, Manning E, Kaminski N, Sauler M, Chen L, Song JW, Kim TK, Kang MJ. Am J Respir Cell Mol Biol. 2023 Jul. PMID: 36450109.
A pref-1-controlled non-inflammatory mechanism of insulin resistance.Huang Y, Cui D, Chen L, Tong H, Wu H, Muller GK, Qi Y, Wang S, Xu J, Gao X, Fifield KE, Wang L, Xia Z, Vanderluit JL, Liu S, Leng L, Sun G, McGuire J, Young LH, Bucala R, Qi D. iScience. 2023 Jun 16; 2023 May 19. PMID: 37283810.
A Picture Worth a Thousand Words, Created with One Sentence: Using Artificial Intelligence-created Art to Enhance Medical Education.Huston JC, Kaminski N. ATS Sch. 2023 Jun; 2023 May 10. PMID: 37533539.
An integrated cell atlas of the lung in health and disease.Sikkema L, Ramírez-Suástegui C, Strobl DC, Gillett TE, Zappia L, Madissoon E, Markov NS, Zaragosi LE, Ji Y, Ansari M, Arguel MJ, Apperloo L, Banchero M, Bécavin C, Berg M, Chichelnitskiy E, Chung MI, Collin A, Gay ACA, Gote-Schniering J, Hooshiar Kashani B, Inecik K, Jain M, Kapellos TS, Kole TM, Leroy S, Mayr CH, Oliver AJ, von Papen M, Peter L, Taylor CJ, Walzthoeni T, Xu C, Bui LT, De Donno C, Dony L, Faiz A, Guo M, Gutierrez AJ, Heumos L, Huang N, Ibarra IL, Jackson ND, Kadur Lakshminarasimha Murthy P, Lotfollahi M, Tabib T, Talavera-López C, Travaglini KJ, Wilbrey-Clark A, Worlock KB, Yoshida M, van den Berge M, Bossé Y, Desai TJ, Eickelberg O, Kaminski N, Krasnow MA, Lafyatis R, Nikolic MZ, Powell JE, Rajagopal J, Rojas M, Rozenblatt-Rosen O, Seibold MA, Sheppard D, Shepherd DP, Sin DD, Timens W, Tsankov AM, Whitsett J, Xu Y, Banovich NE, Barbry P, Duong TE, Falk CS, Meyer KB, Kropski JA, Pe'er D, Schiller HB, Tata PR, Schultze JL, Teichmann SA, Misharin AV, Nawijn MC, Luecken MD, Theis FJ. Nat Med. 2023 Jun; 2023 Jun 8. PMID: 37291214.
Vascular-Parenchymal Cross-Talk Promotes Lung Fibrosis through BMPR2 Signaling.Yanagihara T, Tsubouchi K, Zhou Q, Chong M, Otsubo K, Isshiki T, Schupp JC, Sato S, Scallan C, Upagupta C, Revill S, Ayoub A, Chong SG, Dvorkin-Gheva A, Kaminski N, Tikkanen J, Keshavjee S, Paré G, Guignabert C, Ask K, Kolb MRJ. Am J Respir Crit Care Med. 2023 Jun 1. PMID: 36917778.
Medical Societies Must Choose Professional Meeting Locations Responsibly in a Post-Roe World.Lee AG, Maley J, Hibbert K, Akgün KM, Hauschildt KE, Law A, Kaminski N, Hayes M, Gesthalter Y, Bosslet GT, Santhosh L, Witkin A, Hills-Dunlap K, Çoruh B, Gershengorn HB, Hardin CC. Ann Am Thorac Soc. 2023 Jun. PMID: 36812378.
PCSK6 and Survival in Idiopathic Pulmonary Fibrosis.Oldham JM, Allen RJ, Lorenzo-Salazar JM, Molyneaux PL, Ma SF, Joseph C, Kim JS, Guillen-Guio B, Hernández-Beeftink T, Kropski JA, Huang Y, Lee CT, Adegunsoye A, Pugashetti JV, Linderholm AL, Vo V, Strek ME, Jou J, Muñoz-Barrera A, Rubio-Rodriguez LA, Hubbard R, Hirani N, Whyte MKB, Hart S, Nicholson AG, Lancaster L, Parfrey H, Rassl D, Wallace W, Valenzi E, Zhang Y, Mychaleckyj J, Stockwell A, Kaminski N, Wolters PJ, Molina-Molina M, Banovich NE, Fahy WA, Martinez FJ, Hall IP, Tobin MD, Maher TM, Blackwell TS, Yaspan BL, Jenkins RG, Flores C, Wain LV, Noth I. Am J Respir Crit Care Med. 2023 Jun 1. PMID: 36780644.
Emergence of division of labor in tissues through cell interactions and spatial cues.Adler M, Moriel N, Goeva A, Avraham-Davidi I, Mages S, Adams TS, Kaminski N, Macosko EZ, Regev A, Medzhitov R, Nitzan M. Cell Rep. 2023 May 30; 2023 Apr 21. PMID: 37086403.
Urothelial Oxidative Stress and ERK Activation Mediate HMGB1-Induced Bladder Pain.Ye S, Mahmood DFD, Ma F, Leng L, Bucala R, Vera PL. Cells. 2023 May 22; 2023 May 22. PMID: 37408274.
Correction: Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3.Lee CM, He CH, Park JW, Lee JH, Kamle S, Ma B, Akosman B, Cotez R, Chen E, Zhou Y, Herzog EL, Ryu C, Peng X, Rosas IO, Poli S, Bostwick CF, Choi AM, Elias JA, Lee CG. Life Sci Alliance. 2023 May; 2023 Apr 10. PMID: 37037591.
α1 Adrenoreceptor antagonism mitigates extracellular mitochondrial DNA accumulation in lung fibrosis models and in patients with idiopathic pulmonary fibrosis.Ishikawa G, Peng X, McGovern J, Woo S, Perry C, Liu A, Yu S, Ghincea A, Kishchanka A, Fiorini V, Hu B, Sun Y, Sun H, Ryu C, Herzog EL. Am J Physiol Lung Cell Mol Physiol. 2023 May 1; 2023 Jan 17. PMID: 36648147.
Rational engineering of lung alveolar epithelium.Leiby KL, Yuan Y, Ng R, Raredon MSB, Adams TS, Baevova P, Greaney AM, Hirschi KK, Campbell SG, Kaminski N, Herzog EL, Niklason LE. NPJ Regen Med. 2023 Apr 28; 2023 Apr 28. PMID: 37117221.
Thyroid hormone modulates hyperoxic neonatal lung injury and mitochondrial function.Vamesu BM, Nicola T, Li R, Hazra S, Matalon S, Kaminski N, Ambalavanan N, Kandasamy J. JCI Insight. 2023 Apr 24; 2023 Apr 24. PMID: 36917181.
Proteomic profiling demonstrates inflammatory and endotheliopathy signatures associated with impaired cardiopulmonary exercise hemodynamic profile in Post Acute Sequelae of SARS-CoV-2 infection (PASC) syndrome.Singh I, Leitner BP, Wang Y, Zhang H, Joseph P, Lutchmansingh DD, Gulati M, Possick JD, Damsky W, Hwa J, Heerdt PM, Chun HJ. Pulm Circ. 2023 Apr; 2023 Apr 1. PMID: 37091121.
Transbronchial Lung Cryobiopsy for the Diagnosis of Interstitial Lung Disease: A Right Answer to a Wrong Question Is Still a Wrong Answer.Low SW, Kaminski N, Maldonado F. J Bronchology Interv Pulmonol. 2023 Apr 1; 2023 Apr 1. PMID: 37005378.
SH2 Domain-Containing Phosphatase-SHP2 Attenuates Fibrotic Responses through Negative Regulation of Mitochondrial Metabolism in Lung Fibroblasts.Karampitsakos T, Galaris A, Barbayianni I, DeIuliis G, Ahangari F, Sampsonas F, Sotiropoulou V, Aidinis V, Bennett AM, Herazo-Maya JD, Xylourgidis N, Bakakos P, Bouros D, Kaminski N, Tzouvelekis A. Diagnostics (Basel). 2023 Mar 18; 2023 Mar 18. PMID: 36980473.
Lung cancer with air lucency: a systematic review and clinical management guide.Detterbeck FC, Kumbasar U, Li AX, Rubinowitz AN, Traube L, Gosangi B, Udelsman BV, Bade BC, Ely S, Barreto G, Tanoue LT, Marom EM, Rivera MP. J Thorac Dis. 2023 Feb 28; 2023 Feb 23. PMID: 36910113.
microRNA-33 deficiency in macrophages enhances autophagy, improves mitochondrial homeostasis, and protects against lung fibrosis.Ahangari F, Price NL, Malik S, Chioccioli M, Bärnthaler T, Adams TS, Kim J, Pradeep SP, Ding S, Cosmos C Jr, Rose KS, McDonough JE, Aurelien NR, Ibarra G, Omote N, Schupp JC, DeIuliis G, Villalba Nunez JA, Sharma L, Ryu C, Dela Cruz CS, Liu X, Prasse A, Rosas I, Bahal R, Fernández-Hernando C, Kaminski N. JCI Insight. 2023 Feb 22; 2023 Feb 22. PMID: 36626225.
Low CC16 mRNA Expression Levels in Bronchial Epithelial Cells Are Associated with Asthma Severity.Li X, Guerra S, Ledford JG, Kraft M, Li H, Hastie AT, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Zein J, Kaminski N, Wenzel SE, Woodruff PG, Meyers DA, Bleecker ER. Am J Respir Crit Care Med. 2023 Feb 15. PMID: 36066606.
Lung Cell Atlases in Health and Disease.Adams TS, Marlier A, Kaminski N. Annu Rev Physiol. 2023 Feb 10; 2022 Nov 9. PMID: 36351366.
Single-cell RNA-seq uncovers cellular heterogeneity and provides a signature for paediatric sleep apnoea.Cortese R, Adams TS, Cataldo KH, Hummel J, Kaminski N, Kheirandish-Gozal L, Gozal D. Eur Respir J. 2023 Feb; 2023 Feb 9. PMID: 36356973.
"Long Haulers".Lutchmansingh DD, Higuero Sevilla JP, Possick JD, Gulati M. Semin Respir Crit Care Med. 2023 Feb; 2023 Jan 16. PMID: 36646091.
Correction to: Clinical features and high-risk indicators of central nervous system involvement in primary Sjögren's syndrome.Fan W, Par-Young J, Li K, Zhang Y, Xiao P, Hua L, Leng L, Chen X, Bucala R. Clin Rheumatol. 2023 Feb. PMID: 36565380.
Clinical features and high-risk indicators of central nervous system involvement in primary Sjögren's syndrome.Fan W, Par-Young J, Li K, Zhang Y, Xiao P, Hua L, Leng L, Chen X, Bucala R. Clin Rheumatol. 2023 Feb; 2022 Nov 19. PMID: 36401063.
PD-1(high)CXCR5(-)CD4(+) peripheral helper T cells promote CXCR3(+) plasmablasts in human acute viral infection.Asashima H, Mohanty S, Comi M, Ruff WE, Hoehn KB, Wong P, Klein J, Lucas C, Cohen I, Coffey S, Lele N, Greta L, Raddassi K, Chaudhary O, Unterman A, Emu B, Kleinstein SH, Montgomery RR, Iwasaki A, Dela Cruz CS, Kaminski N, Shaw AC, Hafler DA, Sumida TS. Cell Rep. 2023 Jan 31; 2023 Jan 2. PMID: 36596303.
A novel Bayesian framework for harmonizing information across tissues and studies to increase cell type deconvolution accuracy.Deng W, Li B, Wang J, Jiang W, Yan X, Li N, Vukmirovic M, Kaminski N, Wang J, Zhao H. Brief Bioinform. 2023 Jan 19. PMID: 36631398.
Changes in microRNAs during Storage and Processing of Breast Milk.Kim JH, Kim KU, Min H, Lee ES, Lim IS, Song J, Kang I, Yi DY. Metabolites. 2023 Jan 17; 2023 Jan 17. PMID: 36837760.
Reflections for the 50th Anniversary of The Journal of Rheumatology: The Past, Present, and Future of Rheumatology.Masi AT, Bucala RJ. J Rheumatol. 2023 Jan. PMID: 36587952.
Comprehensive visualization of cell-cell interactions in single-cell and spatial transcriptomics with NICHES.Raredon MSB, Yang J, Kothapalli N, Lewis W, Kaminski N, Niklason LE, Kluger Y. Bioinformatics. 2023 Jan 1. PMID: 36458905.
Effect of Androgen-Androgen Receptor Directed Therapy on COVID-19 Outcome in Prostate Cancer Patients.Ünlü S, Shin JJ, Par-Young J, Simonov M, Vinetz J, Petrylak DP, Kang I, Kim JW. Cancer Invest. 2023 Jan; 2022 Nov 17. PMID: 36373994.
IFN-γ Is Protective in Cytokine Release Syndrome-associated Extrapulmonary Acute Lung Injury.Sun Y, Hu B, Stanley G, Harris ZM, Gautam S, Homer R, Koff JL, Rajagopalan G. Am J Respir Cell Mol Biol. 2023 Jan. PMID: 36125351.
Longitudinal lung function and gas transfer in individuals with idiopathic pulmonary fibrosis: a genome-wide association study.Allen RJ, Oldham JM, Jenkins DA, Leavy OC, Guillen-Guio B, Melbourne CA, Ma SF, Jou J, Kim JS, Fahy WA, Oballa E, Hubbard RB, Navaratnam V, Braybrooke R, Saini G, Roach KM, Tobin MD, Hirani N, Whyte MKB, Kaminski N, Zhang Y, Martinez FJ, Linderholm AL, Adegunsoye A, Strek ME, Maher TM, Molyneaux PL, Flores C, Noth I, Gisli Jenkins R, Wain LV. Lancet Respir Med. 2023 Jan; 2022 Aug 16. PMID: 35985358.

2022

Implication of IL-7 receptor alpha chain expression by CD8(+) T cells and its signature in defining biomarkers in aging.Shin MS, Park HJ, Young J, Kang I. Immun Ageing. 2022 Dec 21; 2022 Dec 21. PMID: 36544153.
Metagenomic sequencing of the bronchoalveolar lavage extracellular virome and cellular transcriptome of sarcoidosis patients does not detect rubella virus.Keeler EL, Vukmirovic M, Yan X, Gulino K, Ghedin E, Kaminski N, Sullivan KE, Bushman FD, Collman RG, Rosenbach M. Sarcoidosis Vasc Diffuse Lung Dis. 2022 Dec 19; 2022 Dec 19. PMID: 36533601.
Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis.Ahangari F, Becker C, Foster DG, Chioccioli M, Nelson M, Beke K, Wang X, Justet A, Adams T, Readhead B, Meador C, Correll K, Lili LN, Roybal HM, Rose KA, Ding S, Barnthaler T, Briones N, DeIuliis G, Schupp JC, Li Q, Omote N, Aschner Y, Sharma L, Kopf KW, Magnusson B, Hicks R, Backmark A, Dela Cruz CS, Rosas I, Cousens LP, Dudley JT, Kaminski N, Downey GP. Am J Respir Crit Care Med. 2022 Dec 15. PMID: 35998281.
Imaging in the Intensive Care Unit.Toy D, Siegel MD, Rubinowitz AN. Semin Respir Crit Care Med. 2022 Dec; 2022 Nov 28. PMID: 36442475.
Macrophage migration inhibitory factor regulates specific innate immune sensor responses in gingival epithelial cells.Kantrong N, Chang AM, Bamashmous S, Hajjar AM, Bucala RJ, Darveau RP. J Periodontol. 2022 Dec; 2022 Feb 24. PMID: 35100435.
Unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses.Mao T, Israelow B, Peña-Hernández MA, Suberi A, Zhou L, Luyten S, Reschke M, Dong H, Homer RJ, Saltzman WM, Iwasaki A. Science. 2022 Nov 25; 2022 Nov 25. PMID: 36302057.
Ameliorating Fibrosis in Murine and Human Tissues with END55, an Endostatin-Derived Fusion Protein Made in Plants.Mlakar L, Garrett SM, Watanabe T, Sanderson M, Nishimoto T, Heywood J, Helke KL, Pilewski JM, Herzog EL, Feghali-Bostwick C. Biomedicines. 2022 Nov 9; 2022 Nov 9. PMID: 36359382.
CD74 as a regulator of transcription in normal B cells.David K, Friedlander G, Pellegrino B, Radomir L, Lewinsky H, Leng L, Bucala R, Becker-Herman S, Shachar I. Cell Rep. 2022 Nov 1. PMID: 36323260.
A lung targeted miR-29 mimic as a therapy for pulmonary fibrosis.Chioccioli M, Roy S, Newell R, Pestano L, Dickinson B, Rigby K, Herazo-Maya J, Jenkins G, Ian S, Saini G, Johnson SR, Braybrooke R, Yu G, Sauler M, Ahangari F, Ding S, DeIuliis J, Aurelien N, Montgomery RL, Kaminski N. EBioMedicine. 2022 Nov; 2022 Oct 17. PMID: 36265417.
Diseases of the pulmonary arteries: imaging appearances and pearls.Cortopassi IO, Gosangi B, Asch D, Bader AS, Gange CP, Rubinowitz AN. Clin Imaging. 2022 Nov; 2022 Aug 30. PMID: 36067656.
PTX3 in Granuloma Formation and Sarcoidosis: Helping Macrophages Accept a "Complement".Ishikawa G, Herzog EL. Am J Respir Crit Care Med. 2022 Nov 1. PMID: 35820078.
Macrophage Migration Inhibitory Factor (MIF) Promotes Increased Proportions of the Highly Permissive Th17-like Cell Profile during HIV Infection.Trifone C, Baquero L, Czernikier A, Benencio P, Leng L, Laufer N, Quiroga MF, Bucala R, Ghiglione Y, Turk G. Viruses. 2022 Oct 9; 2022 Oct 9. PMID: 36298774.
Alterations in high-dimensional T-cell profile and gene signature of immune aging in HIV-infected older adults without viremia.Shin MS, Park HJ, Salahuddin S, Montgomery RR, Emu B, Shaw AC, Kang I. Aging Cell. 2022 Oct; 2022 Aug 29. PMID: 36036630.
Impact of Sex and Gender on Autoimmune Lung Disease: Opportunities for Future Research: NHLBI Working Group Report.Volkmann ER, Siegfried J, Lahm T, Ventetuolo CE, Mathai SC, Steen V, Herzog EL, Shansky R, Anguera MC, Danoff SK, Giles JT, Lee YC, Drake W, Maier LA, Lachowicz-Scroggins M, Park H, Banerjee K, Fessel J, Reineck L, Vuga L, Crouser E, Feghali-Bostwick C. Am J Respir Crit Care Med. 2022 Oct 1. PMID: 35549658.
Airway basal cells show a dedifferentiated KRT17(high)Phenotype and promote fibrosis in idiopathic pulmonary fibrosis.Jaeger B, Schupp JC, Plappert L, Terwolbeck O, Artysh N, Kayser G, Engelhard P, Adams TS, Zweigerdt R, Kempf H, Lienenklaus S, Garrels W, Nazarenko I, Jonigk D, Wygrecka M, Klatt D, Schambach A, Kaminski N, Prasse A. Nat Commun. 2022 Sep 26; 2022 Sep 26. PMID: 36163190.
CINS: Cell Interaction Network inference from Single cell expression data.Yuan Y, Cosme C Jr, Adams TS, Schupp J, Sakamoto K, Xylourgidis N, Ruffalo M, Li J, Kaminski N, Bar-Joseph Z. PLoS Comput Biol. 2022 Sep; 2022 Sep 12. PMID: 36095011.
Stem cells, cell therapies, and bioengineering in lung biology and disease 2021.Ikonomou L, Magnusson M, Dries R, Herzog EL, Hynds RE, Borok Z, Park JA, Skolasinski S, Burgess JK, Turner L, Mojarad SM, Mahoney JE, Lynch T, Lehmann M, Thannickal VJ, Hook JL, Vaughan AE, Hoffman ET, Weiss DJ, Ryan AL. Am J Physiol Lung Cell Mol Physiol. 2022 Sep 1; 2022 Jun 28. PMID: 35762622.
POU2F3 in SCLC: Clinicopathologic and Genomic Analysis With a Focus on Its Diagnostic Utility in Neuroendocrine-Low SCLC.Baine MK, Febres-Aldana CA, Chang JC, Jungbluth AA, Sethi S, Antonescu CR, Travis WD, Hsieh MS, Roh MS, Homer RJ, Ladanyi M, Egger JV, Lai WV, Rudin CM, Rekhtman N. J Thorac Oncol. 2022 Sep; 2022 Jun 24. PMID: 35760287.
Kasugamycin Is a Novel Chitinase 1 Inhibitor with Strong Antifibrotic Effects on Pulmonary Fibrosis.Lee JH, Lee CM, Lee JH, Kim MO, Park JW, Kamle S, Akosman B, Herzog EL, Peng XY, Elias JA, Lee CG. Am J Respir Cell Mol Biol. 2022 Sep. PMID: 35679109.
CD38 Mediates Lung Fibrosis by Promoting Alveolar Epithelial Cell Aging.Cui H, Xie N, Banerjee S, Dey T, Liu RM, Antony VB, Sanders YY, Adams TS, Gomez JL, Thannickal VJ, Kaminski N, Liu G. Am J Respir Crit Care Med. 2022 Aug 15. PMID: 35687485.
Microenvironmental sensing by fibroblasts controls macrophage population size.Zhou X, Franklin RA, Adler M, Carter TS, Condiff E, Adams TS, Pope SD, Philip NH, Meizlish ML, Kaminski N, Medzhitov R. Proc Natl Acad Sci U S A. 2022 Aug 9; 2022 Aug 5. PMID: 35930670.
Occupational and environmental exposures in the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis (GRADS) study.Ryan SM, Mroz MM, Herzog EL, Ryu C, Fingerlin TE, Maier LA, Gulati M. Respir Med. 2022 Aug-Sep; 2022 Jun 30. PMID: 35932543.
"Near Cure" treatment of severe acute EAE in MIF-1-deficient female and male mice with a bifunctional MHCII-derived molecular construct.Vandenbark AA, Meza-Romero R, Wiedrick J, Gerstner G, Seifert H, Kent G, Piechycna M, Benedek G, Bucala R, Offner H. Cell Immunol. 2022 Aug; 2022 Jun 11. PMID: 35738135.
Defining Clinical and Immunological Predictors of Poor Immune Responses to COVID-19 mRNA Vaccines in Patients with Primary Antibody Deficiency.Shin JJ, Par-Young J, Unlu S, McNamara A, Park HJ, Shin MS, Gee RJ, Doyle H, Afinogenova Y, Zidan E, Kwah J, Russo A, Mamula M, Hsu FI, Catanzaro J, Racke M, Bucala R, Wilen C, Kang I. J Clin Immunol. 2022 Aug; 2022 Jun 17. PMID: 35713752.
Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation.Fernández-Castañeda A, Lu P, Geraghty AC, Song E, Lee MH, Wood J, O'Dea MR, Dutton S, Shamardani K, Nwangwu K, Mancusi R, Yalçın B, Taylor KR, Acosta-Alvarez L, Malacon K, Keough MB, Ni L, Woo PJ, Contreras-Esquivel D, Toland AMS, Gehlhausen JR, Klein J, Takahashi T, Silva J, Israelow B, Lucas C, Mao T, Peña-Hernández MA, Tabachnikova A, Homer RJ, Tabacof L, Tosto-Mancuso J, Breyman E, Kontorovich A, McCarthy D, Quezado M, Vogel H, Hefti MM, Perl DP, Liddelow S, Folkerth R, Putrino D, Nath A, Iwasaki A, Monje M. Cell. 2022 Jul 7; 2022 Jun 13. PMID: 35768006.
Rationale and design of the SARCoidosis Outcomes in all respiratory Viral Infectious Diseases (SARCOVID) Study.Strykowski R, Patel DC, Neto MR, Hena KM, Gulati M, Maier LA, Patterson K. BMJ Open Respir Res. 2022 Jul. PMID: 35882424.
Development of an immunohistochemical assay for Siglec-15.Shafi S, Aung TN, Robbins C, Zugazagoitia J, Vathiotis I, Gavrielatou N, Yaghoobi V, Fernandez A, Niu S, Liu LN, Cusumano ZT, Leelatian N, Cole K, Wang H, Homer R, Herbst RS, Langermann S, Rimm DL. Lab Invest. 2022 Jul; 2022 Apr 22. PMID: 35459795.
Arthritis & Rheumatology: "Mid-Term" Report.Solomon DH, Bucala R, Kaplan MJ, Nigrovic PA. Arthritis Rheumatol. 2022 Jul; 2022 May 6. PMID: 35358367.
From COVID to fibrosis: lessons from single-cell analyses of the human lung.Justet A, Zhao AY, Kaminski N. Hum Genomics. 2022 Jun 13; 2022 Jun 13. PMID: 35698166.
Inhibition of type 1 immunity with tofacitinib is associated with marked improvement in longstanding sarcoidosis.Damsky W, Wang A, Kim DJ, Young BD, Singh K, Murphy MJ, Daccache J, Clark A, Ayasun R, Ryu C, McGeary MK, Odell ID, Fazzone-Chettiar R, Pucar D, Homer R, Gulati M, Miller EJ, Bosenberg M, Flavell RA, King B. Nat Commun. 2022 Jun 6; 2022 Jun 6. PMID: 35668129.
T Cell Response to Influenza Vaccination Remains Intact in Adults with Congenital Heart Disease Who Underwent Early Thymectomy.Leone DM, Park HJ, Unlu S, Gurvitz M, Kang I, Elder RW. Int J Cardiol Congenit Heart Dis. 2022 Jun; 2022 Mar 25. PMID: 35600131.
Bronchial epithelium epithelial-mesenchymal plasticity forms aberrant basaloid-like cells in vitro.Uthaya Kumar DB, Motakis E, Yurieva M, Kohar V, Martinek J, Wu TC, Khoury J, Grassmann J, Lu M, Palucka K, Kaminski N, Koff JL, Williams A. Am J Physiol Lung Cell Mol Physiol. 2022 Jun 1; 2022 Apr 19. PMID: 35438006.
BAL Transcriptomes Characterize Idiopathic Pulmonary Fibrosis Endotypes With Prognostic Impact.De Sadeleer LJ, Verleden SE, Schupp JC, McDonough JE, Goos T, Yserbyt J, Bargagli E, Rottoli P, Kaminski N, Prasse A, Wuyts WA. Chest. 2022 Jun; 2022 Jan 19. PMID: 35063449.
Standardizing the Reporting of Incidental, Non-Lung Cancer (Category S) Findings Identified on Lung Cancer Screening Low-Dose CT Imaging.Tanoue LT, Sather P, Cortopassi I, Dicks D, Curtis A, Michaud G, Bader A, Gange C Jr, Detterbeck F, Killam J. Chest. 2022 Jun; 2022 Jan 12. PMID: 35032477.
No evidence of fetal defects or anti-syncytin-1 antibody induction following COVID-19 mRNA vaccination.Lu-Culligan A, Tabachnikova A, Pérez-Then E, Tokuyama M, Lee HJ, Lucas C, Silva Monteiro V, Miric M, Brache V, Cochon L, Muenker MC, Mohanty S, Huang J, Kang I, Dela Cruz C, Farhadian S, Campbell M, Yildirim I, Shaw AC, Ma S, Vermund SH, Ko AI, Omer SB, Iwasaki A. PLoS Biol. 2022 May; 2022 May 24. PMID: 35609110.
Long-term evaluation of the safety and efficacy of recombinant human pentraxin-2 (rhPTX-2) in patients with idiopathic pulmonary fibrosis (IPF): an open-label extension study.Raghu G, Hamblin MJ, Brown AW, Golden JA, Ho LA, Wijsenbeek MS, Vasakova M, Pesci A, Antin-Ozerkis DE, Meyer KC, Kreuter M, Burgess T, Kamath N, Donaldson F, Richeldi L. Respir Res. 2022 May 21; 2022 May 21. PMID: 35597980.
Bladder Oxidative Stress and HMGB1 Release Contribute to PAR4-Mediated Bladder Pain in Mice.Ye S, Ma F, Mahmood DFD, Meyer-Siegler KL, Leng L, Bucala R, Vera PL. Front Syst Neurosci. 2022; 2022 May 13. PMID: 35645739.
Mindfulness-based stress reduction may decrease stress, disease activity, and inflammatory cytokine levels in patients with autoimmune hepatitis.Alrabadi LS, Dutton A, Rabiee A, Roberts SJ, Deng Y, Cusack L, Silveira MG, Ciarleglio M, Bucala R, Sinha R, Boyer JL, Assis DN. JHEP Rep. 2022 May; 2022 Feb 18. PMID: 35434588.
Interleukin-17 Contributes to Chikungunya Virus-Induced Disease.Liu X, Poo YS, Alves JC, Almeida RP, Mostafavi H, Tang PCH, Bucala R, Teixeira MM, Taylor A, Zaid A, Mahalingam S. mBio. 2022 Apr 26; 2022 Mar 7. PMID: 35254128.
AHCC(®), a Standardized Extract of Cultured Lentinula Edodes Mycelia, Promotes the Anti-Tumor Effect of Dual Immune Checkpoint Blockade Effect in Murine Colon Cancer.Park HJ, Boo S, Park I, Shin MS, Takahashi T, Takanari J, Homma K, Kang I. Front Immunol. 2022; 2022 Apr 20. PMID: 35514996.
FK506-Binding Protein 11 Is a Novel Plasma Cell-Specific Antibody Folding Catalyst with Increased Expression in Idiopathic Pulmonary Fibrosis.Preisendörfer S, Ishikawa Y, Hennen E, Winklmeier S, Schupp JC, Knüppel L, Fernandez IE, Binzenhöfer L, Flatley A, Juan-Guardela BM, Ruppert C, Guenther A, Frankenberger M, Hatz RA, Kneidinger N, Behr J, Feederle R, Schepers A, Hilgendorff A, Kaminski N, Meinl E, Bächinger HP, Eickelberg O, Staab-Weijnitz CA. Cells. 2022 Apr 14; 2022 Apr 14. PMID: 35456020.
Type I interferon transcriptional network regulates expression of coinhibitory receptors in human T cells.Sumida TS, Dulberg S, Schupp JC, Lincoln MR, Stillwell HA, Axisa PP, Comi M, Unterman A, Kaminski N, Madi A, Kuchroo VK, Hafler DA. Nat Immunol. 2022 Apr; 2022 Mar 17. PMID: 35301508.
Emerging insights in sarcoidosis: moving forward through reverse translational research.Liu A, Sharma L, Yan X, Dela Cruz CS, Herzog EL, Ryu C. Am J Physiol Lung Cell Mol Physiol. 2022 Apr 1; 2022 Feb 23. PMID: 35196896.
Computation and visualization of cell-cell signaling topologies in single-cell systems data using Connectome.Raredon MSB, Yang J, Garritano J, Wang M, Kushnir D, Schupp JC, Adams TS, Greaney AM, Leiby KL, Kaminski N, Kluger Y, Levchenko A, Niklason LE. Sci Rep. 2022 Mar 9; 2022 Mar 9. PMID: 35264704.
Pseudohypoxic HIF pathway activation dysregulates collagen structure-function in human lung fibrosis.Brereton CJ, Yao L, Davies ER, Zhou Y, Vukmirovic M, Bell JA, Wang S, Ridley RA, Dean LSN, Andriotis OG, Conforti F, Brewitz L, Mohammed S, Wallis T, Tavassoli A, Ewing RM, Alzetani A, Marshall BG, Fletcher SV, Thurner PJ, Fabre A, Kaminski N, Richeldi L, Bhaskar A, Schofield CJ, Loxham M, Davies DE, Wang Y, Jones MG. Elife. 2022 Feb 21; 2022 Feb 21. PMID: 35188460.
Correction to: Association of Circulating Proteins with Death or Lung Transplant in Patients with Idiopathic Pulmonary Fibrosis in the IPF-PRO Registry Cohort.Todd JL, Neely ML, Overton R, Mulder H, Roman J, Lasky JA, de Andrade JA, Gulati M, Huang H, Leonard TB, Hesslinger C, Noth I, Belperio JA, Flaherty KR, Palmer SM. Lung. 2022 Feb. PMID: 35166906.
An Acute Exacerbation of Idiopathic Pulmonary Fibrosis After BNT162b2 mRNA COVID-19 Vaccination: A Case Report.Ghincea A, Ryu C, Herzog EL. Chest. 2022 Feb. PMID: 35131075.
Targeting fibrocytes in autoimmunity.Bucala RJ. Proc Natl Acad Sci U S A. 2022 Feb 1. PMID: 35086933.
Association of Circulating Proteins with Death or Lung Transplant in Patients with Idiopathic Pulmonary Fibrosis in the IPF-PRO Registry Cohort.Todd JL, Neely ML, Overton R, Mulder H, Roman J, Lasky JA, de Andrade JA, Gulati M, Huang H, Leonard TB, Hesslinger C, Noth I, Belperio JA, Flaherty KR, Palmer SM. Lung. 2022 Feb; 2022 Jan 23. PMID: 35066606.