1995
Hepatic ultrasonic changes in workers exposed to perchloroethylene.
Brodkin C, Daniell W, Checkoway H, Echeverria D, Johnson J, Wang K, Sohaey R, Green D, Redlich C, Gretch D. Hepatic ultrasonic changes in workers exposed to perchloroethylene. Occupational And Environmental Medicine 1995, 52: 679. PMID: 7489059, PMCID: PMC1128334, DOI: 10.1136/oem.52.10.679.Peer-Reviewed Original ResearchConceptsHepatic transaminase activityTransaminase activityParenchymal changesLaundry workersPerchloroethylene exposureDiffuse parenchymal changesAlanine aminotransferase activityHepatic parenchymal changesDry cleanersSubclinical hepatotoxicityHepatic ultrasonographyParenchymal echogenicityNormal limitsPermissible exposure limitUltrasonic changesControl groupAminotransferase activityUltrasonographyExposure limitsEchogenicityExposureWork historyHepatotoxicityActivityWorkers
1990
Clinical and pathological characteristics of hepatotoxicity associated with occupational exposure to dimethylformamide
Redlich C, West A, Fleming L, True L, Cullen M, Riely C. Clinical and pathological characteristics of hepatotoxicity associated with occupational exposure to dimethylformamide. Gastroenterology 1990, 99: 748-757. PMID: 2379779, DOI: 10.1016/0016-5085(90)90964-3.Peer-Reviewed Original ResearchConceptsToxic liver injuryLiver injuryDisulfiram-type reactionsFocal hepatocellular necrosisSmooth endoplasmic reticulumProminent smooth endoplasmic reticulumAbnormal aminotransferasesAbdominal painBiopsy findingsClinical characteristicsEnzyme elevationLiver biopsyPleomorphic mitochondriaAcute injuryHepatocellular necrosisMicrovesicular steatosisBiopsy histologyMacrovesicular steatosisPathological characteristicsOccupational exposureAlanine aminotransferaseOccupational historyLonger exposureInjuryAminotransferaseLiver injury in workers exposed to dimethylformamide.
Fleming L, Shalat S, Redlich C. Liver injury in workers exposed to dimethylformamide. Scandinavian Journal Of Work, Environment & Health 1990, 16: 289-92. PMID: 2389137, DOI: 10.5271/sjweh.1782.Peer-Reviewed Original ResearchConceptsToxic liver diseaseGlutamic pyruvic transaminaseLiver diseasePyruvic transaminaseOxaloacetic transaminaseSerum glutamic oxaloacetic transaminaseSerum glutamic pyruvic transaminaseGlutamic oxaloacetic transaminaseLiver transaminasesLiver injuryUnexposed groupOriginal epidemicUnexposed subjectsMedical surveillanceEpidemic clustersOccupational diseasesFurther casesTransaminaseDiseaseCausative agentSignificant differencesPopulationInjuryOccupational clustersMonths