2012
MyD88 Expression on Villin Inhibits Obesity in High Fat Diet Mice (120.5)
Chao C, Xiang Y, Wang Y, Peng J, Hu Y, Tai N, Hoshi N, Zhou Z, Medzhitov R, Wen L. MyD88 Expression on Villin Inhibits Obesity in High Fat Diet Mice (120.5). The Journal Of Immunology 2012, 188: 120.5-120.5. DOI: 10.4049/jimmunol.188.supp.120.5.Peer-Reviewed Original ResearchHigh-fat dietWhite adipose tissue weightEpithelial brush borderTotal body fat massHigh-fat diet miceAdipose tissue weightMesenteric lymph nodesInsulin tolerance testWild-type B6Body fat massFat diet miceLower body weightWhite adipose tissueBrush borderTransgenic mouse lineInhibits obesityMore EnterococcusLymph nodesMetabolic syndromeDiet miceB6 miceIL-6MyD88 expressionFat dietTolerance test
2011
IL-10-conditioned dendritic cells prevent autoimmune diabetes in NOD and humanized HLA-DQ8/RIP-B7.1 mice
Tai N, Yasuda H, Xiang Y, Zhang L, Rodriguez-Pinto D, Yokono K, Sherwin R, Wong FS, Nagata M, Wen L. IL-10-conditioned dendritic cells prevent autoimmune diabetes in NOD and humanized HLA-DQ8/RIP-B7.1 mice. Clinical Immunology 2011, 139: 336-349. PMID: 21458378, DOI: 10.1016/j.clim.2011.03.003.Peer-Reviewed Original ResearchMeSH KeywordsAdoptive TransferAnimalsB7-1 AntigenDendritic CellsDiabetes Mellitus, Type 1Disease Models, AnimalFemaleHLA-DQ AntigensHumansImmune ToleranceImmunophenotypingInsulin-Secreting CellsInterleukin-10Lymphocyte ActivationMaleMiceMice, Inbred BALB CMice, Inbred NODMice, SCIDMice, TransgenicSpecific Pathogen-Free OrganismsT-LymphocytesConceptsRIP-B7.1 miceAutoimmune diabetesIL-10IL-10-treated DCIL-12/23 p40T cell toleranceT cell proliferationDifferent animal modelsNew therapeutic interventionsSpontaneous diabetesRegulatory cellsDendritic cellsImmune toleranceCostimulatory moleculesIL-6IL-4T cellsAnimal modelsCell toleranceTherapeutic interventionsDiabetesCell proliferationT1D.MiceCells