2020
Home PAP devices in patients infected with COVID-19.
Kryger M, Thomas R. Home PAP devices in patients infected with COVID-19. Journal Of Clinical Sleep Medicine 2020, 16: 1217-1219. PMID: 32268933, PMCID: PMC7954070, DOI: 10.5664/jcsm.8490.Peer-Reviewed Original Research
1992
Polysomnography in Acutely III Intensive Care Unit Patients
Buckle P, Pouliot Z, Millar T, Kerr P, Kryger M. Polysomnography in Acutely III Intensive Care Unit Patients. CHEST Journal 1992, 102: 288-291. PMID: 1623769, DOI: 10.1378/chest.102.1.288.Peer-Reviewed Original ResearchConceptsCase reportDescriptive studyDouble-blind clinical trialIntensive care unit patientsStudy designCare unit patientsSeries of patientsCase report studySeries of casesUnit patientsCause of diseaseInvestigational protocolsClinical trialsClinical relevanceClinical researchReport studyChestGold standardPatientsReportPolysomnographyTherapyStudyNasal CPAP Reduces Gastroesophageal Reflux in Obstructive Sleep Apnea Syndrome
Kerr P, Shoenut J, Millar T, Buckle P, Kryger M. Nasal CPAP Reduces Gastroesophageal Reflux in Obstructive Sleep Apnea Syndrome. CHEST Journal 1992, 101: 1539-1544. PMID: 1600771, DOI: 10.1378/chest.101.6.1539.Peer-Reviewed Original ResearchConceptsNocturnal gastroesophageal refluxGastroesophageal refluxNasal CPAPIntrathoracic pressureNasal continuous positive airway pressureObstructive sleep apnea syndrome (OSAS) patientsContinuous positive airway pressureSleep apnea syndrome patientsObstructive sleep apnea syndromePositive airway pressureSleep apnea syndromeEsophageal pressure recordingAntireflux therapyGER frequencyAirway pressureOSAS patientsApnea syndromeClinical impressionSyndrome patientsPressure recordingsCPAPPatientsConsecutive daysNight twoMean percentage
1991
Effect of Theophylline on Lung Function Tests, Sleep Quality, and Nighttime SaO2 in Children with Cystic Fibrosis
Avital A, Sanchez I, Holbrow J, Kryger M, Chernick V. Effect of Theophylline on Lung Function Tests, Sleep Quality, and Nighttime SaO2 in Children with Cystic Fibrosis. American Journal Of Respiratory And Critical Care Medicine 1991, 144: 1245-1249. PMID: 1741534, DOI: 10.1164/ajrccm/144.6.1245.Peer-Reviewed Original ResearchMeSH KeywordsChildCystic FibrosisDouble-Blind MethodFemaleHeart RateHumansMaleMonitoring, PhysiologicOxygenRespiratory Function TestsSleepTheophyllineConceptsEffect of theophyllineCystic fibrosisMicrograms/Heart rateGroup 2Better baseline lung functionT blood levelsBaseline lung functionIncidence of apneaLung function testsSerum T levelsLower heart rateTotal wake timePulmonary functionLung functionSerum levelsFunction testsMean SaO2Blood levelsSleep qualitySleep efficiencyGroup 1Sleep laboratoryT levelsWake time
1990
The Entrainment of Low Frequency Breathing Periodicity
Millar T, Hardy P, Hunt B, Frais M, Kryger M. The Entrainment of Low Frequency Breathing Periodicity. CHEST Journal 1990, 98: 1143-1148. PMID: 2225959, DOI: 10.1378/chest.98.5.1143.Peer-Reviewed Original Research
1989
Respiration and Abnormal Sleep in Patients with Congestive Heart Failure
Hanly B, Millar T, Steljes D, Boert R, Frais M, Kryger M. Respiration and Abnormal Sleep in Patients with Congestive Heart Failure. CHEST Journal 1989, 96: 480-488. PMID: 2766808, DOI: 10.1378/chest.96.3.480.Peer-Reviewed Original ResearchConceptsCheyne-Stokes respirationCongestive heart failureStage 2 NREM sleepSlow-wave sleepSleep stage changesNREM sleepHyperpneic phaseHeart failureREM sleepAwake arterial oxygen saturationStable congestive heart failureSevere congestive heart failureStage 1Mean minimum SaO2Outcomes of patientsNumber of arousalsArterial oxygen saturationStage 1 sleepMinimum SaO2Severe hypoxemiaArterial oxygenationSignificant hypoxemiaClinical statusMean durationAbnormal sleep
1988
Mortality and Apnea Index in Obstructive Sleep Apnea Experience in 385 Male Patients
He J, Kryger M, Zorick F, Conway W, Roth T. Mortality and Apnea Index in Obstructive Sleep Apnea Experience in 385 Male Patients. CHEST Journal 1988, 94: 9-14. PMID: 3289839, DOI: 10.1378/chest.94.1.9.Peer-Reviewed Original ResearchConceptsApnea indexObstructive sleep apneaNasal CPAPOSA patientsCumulative survivalObstructive sleep apnea experienceEight-year survivalMale OSAS patientsUntreated OSA patientsGreater mortalityYears of ageUPPP patientsLatter patientsMale patientsSleep apneaPatientsSurvival curvesMortalityTracheostomyCPAPSurvivalIndexApneaUPPPTherapyIdentification and Quantification of Apneas by Computer-based Analysis of Oxygen Saturation
George C, Millar T, Kryger M. Identification and Quantification of Apneas by Computer-based Analysis of Oxygen Saturation. American Journal Of Respiratory And Critical Care Medicine 1988, 137: 1238-1240. PMID: 3195821, DOI: 10.1164/ajrccm/137.5.1238.Peer-Reviewed Original ResearchMeSH KeywordsAdultHumansMaleMonitoring, PhysiologicOxygenSignal Processing, Computer-AssistedSleep Apnea SyndromesConceptsApnea-hypopnea indexApnea-hypopnea eventsNight polysomnogramsObstructive sleep apneaSleep apneaOvernight studyOxygen saturationSaO2 changesPredictive valueFalse negative rateApneaApnea eventsPolysomnogramSaO2 dataMethod of detectionOverall numberDurationNegative rateTotal numberManual scoringSaO2PatientsSleep Apnea and Body Position during Sleep
George C, Millar T, Kryger M. Sleep Apnea and Body Position during Sleep. Sleep 1988, 11: 90-99. PMID: 3363274, DOI: 10.1093/sleep/11.1.90.Peer-Reviewed Original ResearchMeSH KeywordsAdultHumansMaleMiddle AgedMonitoring, PhysiologicObesityPostureSleep Apnea SyndromesSleep StagesSleep, REMConceptsApnea-hypopnea indexRapid eye movementLateral decubitus positionApnea durationObese patientsSleep apneaDecubitus positionBody positionSleep stagesSevere sleep apneaObstructive sleep apneaNon-REM sleepMajor treatment interventionApnea frequencyOvernight studyPatientsTreatment interventionsApneaNREMEye movementsSleepPrevious studiesPolysomnogramSupinePosition changes
1987
Trial of a Dopaminergic Antidepressant in Obstructive Sleep Apnea
George C, West P, Millar T, Kryger M. Trial of a Dopaminergic Antidepressant in Obstructive Sleep Apnea. Sleep 1987, 10: 180-183. PMID: 3589330, DOI: 10.1093/sleep/10.2.180.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaAnticholinergic side effectsSleep apneaSide effectsImmune hemolytic anemiaCentral nervous system stimulant propertiesPharmacologic therapyUseful therapyEffective therapyUnacceptable incidenceDopaminergic antidepressantsHemolytic anemiaNomifensineRigorous scientific testingStimulant propertiesTherapyApneaAntidepressantsPatientsAnemiaDopaminergicIncidenceTrialsScientific testingProtriptyline
1983
Continuous Monitoring of Respiratory Variables During Sleep by Microcomputer
West P, Kryger M. Continuous Monitoring of Respiratory Variables During Sleep by Microcomputer. Methods Of Information In Medicine 1983, 22: 198-203. PMID: 6656660, DOI: 10.1055/s-0038-1635436.Peer-Reviewed Original Research