2022
Tu1429: FREQUENCY AND CHARACTERISTICS OF NUTRITION ASSESSMENT IN HOSPITALIZED ULCERATIVE COLITIS PATIENTS
Levine L, Sharma S, McMillan C, Li D, Gaidos J, Proctor D, Al Bawardy B. Tu1429: FREQUENCY AND CHARACTERISTICS OF NUTRITION ASSESSMENT IN HOSPITALIZED ULCERATIVE COLITIS PATIENTS. Gastroenterology 2022, 162: s-957. DOI: 10.1016/s0016-5085(22)62267-4.Peer-Reviewed Original ResearchHospitalized ulcerative colitis patientsUlcerative colitis patientsColitis patientsNutrition assessmentPatientsOUTCOMES OF TOTAL PROCTOCOLECTOMY (TPC) WITH ILEAL POUCH ANAL ANASTOMOSIS (IPAA)
Petrov J, Al-Bawardy B, Gaidos J, Proctor D. OUTCOMES OF TOTAL PROCTOCOLECTOMY (TPC) WITH ILEAL POUCH ANAL ANASTOMOSIS (IPAA). Inflammatory Bowel Diseases 2022, 28: s75-s76. DOI: 10.1093/ibd/izac015.123.Peer-Reviewed Original ResearchIleal pouch-anal anastomosisPouch-anal anastomosisTotal proctocolectomyMedical therapyCrohn's diseaseChronic pouchitisRepeat surgeryAnal anastomosisAnatomic complicationsChronic antibiotic-refractory pouchitisAntibiotic-refractory pouchitisBiopsy-proven inflammationChronic steroid therapyEpisodes of pouchitisPre-pouch ileitisSymptoms of pouchitisAdverse postoperative outcomesRate of complicationsSurgery of choiceUlcerative colitis patientsTreatment of complicationsMulti-center studyThird of subjectsAcute pouchitisAnatomical complications
2016
JAK2 Disease-Risk Variants Are Gain of Function and JAK Signaling Threshold Determines Innate Receptor-Induced Proinflammatory Cytokine Secretion in Macrophages
Hedl M, Proctor DD, Abraham C. JAK2 Disease-Risk Variants Are Gain of Function and JAK Signaling Threshold Determines Innate Receptor-Induced Proinflammatory Cytokine Secretion in Macrophages. The Journal Of Immunology 2016, 197: 3695-3704. PMID: 27664279, PMCID: PMC5127452, DOI: 10.4049/jimmunol.1600845.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseAnti-inflammatory cytokinesImmune-mediated diseasesOligomerization domain 2Proinflammatory cytokinesMyeloid cellsJAK2 expressionJAK inhibitorsIntestinal myeloid cellsThymic stromal lymphopoietinUlcerative colitis patientsProinflammatory cytokine secretionPattern recognition receptorsHuman myeloid cellsLower JAK2Cell typesColitis patientsBowel diseaseIL-10IL-22Peripheral macrophagesIL-4Cytokine secretionAA carriersDecreased response