Surgical and molecular characterization of primary and metastatic disease in a neuroendocrine tumor arising in a tailgut cyst
Erdrich J, Schaberg KB, Khodadoust MS, Zhou L, Shelton AA, Visser BC, Ford JM, Alizadeh AA, Quake SR, Kunz PL, Beausang JF. Surgical and molecular characterization of primary and metastatic disease in a neuroendocrine tumor arising in a tailgut cyst. Molecular Case Studies 2018, 4: a003004. PMID: 30087100, PMCID: PMC6169824, DOI: 10.1101/mcs.a003004.Peer-Reviewed Original ResearchMeSH KeywordsAgedBRCA1 ProteinCarcinoid TumorCystsHamartomaHumansLiverLiver NeoplasmsMaleNeoplasm MetastasisNeuroendocrine TumorsSacrococcygeal RegionConceptsGene expression profilesTranscriptomic analysisExpression profilesGenomic characteristicsMolecular characterizationPutative cellSomatic mutationsL cellsGenomic profilingGastrointestinal cellsCellsUnknown significanceNeuroendocrine tumorsFrameshiftMutationsTailgut cystEnteroendocrine L cellsProfilingOriginGenomic testingPotential therapeutic optionRare neuroendocrine tumors