2020
Identifying and managing infectious disease syndemics in patients with HIV.
Bromberg DJ, Mayer KH, Altice FL. Identifying and managing infectious disease syndemics in patients with HIV. Current Opinion In HIV And AIDS 2020, 15: 232-242. PMID: 32487816, PMCID: PMC7376494, DOI: 10.1097/coh.0000000000000631.Peer-Reviewed Original ResearchConceptsInfectious diseasesDisease progressionHIV disease progressionInfluence of HIVEvidence-based interventionsAntiretroviral therapyHIV acquisitionPsychiatric comorbidityRisky sex behaviorsHIVRisk behaviorsDiseaseSubstance useInfectionSex behaviorDisease synergismSyndemicSynergistic interactionIntervention strategiesBehavioral determinantsPatientsMultipronged approachProgressionStructural determinantsPast year
2019
Evaluation of HIV risk and outcomes in a nationally representative sample of incarcerated women in Azerbaijan, Kyrgyzstan, and Ukraine
Ranjit YS, Azbel L, Krishnan A, Altice FL, Meyer JP. Evaluation of HIV risk and outcomes in a nationally representative sample of incarcerated women in Azerbaijan, Kyrgyzstan, and Ukraine. AIDS Care 2019, 31: 793-797. PMID: 30701981, PMCID: PMC6510603, DOI: 10.1080/09540121.2019.1573969.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntiretroviral Therapy, Highly ActiveAzerbaijanCommunicable DiseasesComorbidityContinuity of Patient CareFemaleHealth Services AccessibilityHepatitis CHIV InfectionsHumansKyrgyzstanMaleMental DisordersMiddle AgedPrevalencePrisonersPrisonsSubstance-Related DisordersSurveys and QuestionnairesSyphilisUkraineConceptsAlcohol use disorderAntiretroviral therapyHIV preventionHIV riskHIV care continuumCells/μLHigh-risk groupComorbid substance useEffective HIV preventionGlobal HIV preventionHigh rateHepatitis CIncarcerated womenHIV testingHIV incidenceHIV prevalencePsychiatric comorbidityDrug injectionRepresentative sampleCare continuumRisk groupsPsychiatric disordersMost womenUse disordersTreatment interventions
2017
Predictors of linkage to HIV care and viral suppression after release from jails and prisons: a retrospective cohort study
Loeliger KB, Altice FL, Desai MM, Ciarleglio MM, Gallagher C, Meyer JP. Predictors of linkage to HIV care and viral suppression after release from jails and prisons: a retrospective cohort study. The Lancet HIV 2017, 5: e96-e106. PMID: 29191440, PMCID: PMC5807129, DOI: 10.1016/s2352-3018(17)30209-6.Peer-Reviewed Original ResearchConceptsHIV treatment outcomesHIV careViral suppressionTreatment outcomesPoor HIV treatment outcomesMore medical comorbiditiesPost-release linkagePredictors of linkageRetrospective cohort studyDetectable viral loadCase management servicesCase management dataTransitional case managementHealth care goalsAntiretroviral therapyMedical comorbiditiesCohort studyRetrospective cohortDays of releaseViral loadPharmacy databasePsychiatric comorbidityUS National InstitutesCase management needsHispanic ethnicityPredictors of Linkage to and Retention in HIV Care Following Release from Connecticut Jails and Prisons
Loeliger K, Altice F, Desai M, Ciarleglio M, Gallagher C, Meyer J. Predictors of Linkage to and Retention in HIV Care Following Release from Connecticut Jails and Prisons. Open Forum Infectious Diseases 2017, 4: s38-s38. PMCID: PMC5632019, DOI: 10.1093/ofid/ofx162.092.Peer-Reviewed Original ResearchTime of linkageHIV-1 RNA testsCase managementHigher medical comorbidityPredictors of linkageViral suppression statusHIV treatment outcomesCase management dataPrior observational studiesTransitional case managementHIV careMedical comorbiditiesViral suppressionDetectable viremiaRetrospective cohortHIV outcomesRNA testIndependent correlatesPsychiatric comorbidityIncarceration periodsTreatment outcomesObservational studySuppression statusTargeted interventionsComorbidities
2015
Challenges in managing HIV in people who use drugs
Kamarulzaman A, Altice FL. Challenges in managing HIV in people who use drugs. Current Opinion In Infectious Diseases 2015, 28: 10-16. PMID: 25490106, PMCID: PMC4409950, DOI: 10.1097/qco.0000000000000125.Peer-Reviewed Original ResearchMeSH KeywordsAnti-HIV AgentsCoinfectionComorbidityContinuity of Patient CareHealth Services AccessibilityHepatitis CHIV InfectionsHumansMedication AdherenceMental DisordersNeedle-Exchange ProgramsOpiate Substitution TreatmentSocial ClassSubstance Abuse, IntravenousSubstance-Related DisordersTuberculosisConceptsOpioid substitution therapyHepatitis C virusHIV continuumTreatment outcomesImproved ART adherenceInterferon-based regimesTB treatment outcomesHIV treatment outcomesBetter treatment retentionEvidence-based preventionHIV treatment accessHIV-HCVNoninfectious comorbiditiesOST servicesCare retentionART adherenceHIV managementAntiretroviral adherencePsychiatric comorbiditySubstitution therapyHIV treatmentNew diagnostic technologiesC virusClinical managementEarly diagnosis
2014
HIV in people reincarcerated in Connecticut prisons and jails: an observational cohort study
Meyer JP, Cepeda J, Springer SA, Wu J, Trestman RL, Altice FL. HIV in people reincarcerated in Connecticut prisons and jails: an observational cohort study. The Lancet HIV 2014, 1: e77-e84. PMID: 25473651, PMCID: PMC4249702, DOI: 10.1016/s2352-3018(14)70022-0.Peer-Reviewed Original ResearchViral suppressionHIV treatment outcomesInhibitor-based regimensObservational cohort studyHIV viral suppressionART regimenCohort studyRetrospective cohortPrimary outcomeViral loadPsychiatric comorbidityTreatment outcomesIdentification of individualsHIVJail detaineesLaboratory databaseTreatment potencyDrug abuseRNA copiesNational InstitutePrison releasePublic healthBlack menIncarceration periodsOutcomes
2013
Contribution of Substance Use Disorders on HIV Treatment Outcomes and Antiretroviral Medication Adherence Among HIV-Infected Persons Entering Jail
Chitsaz E, Meyer JP, Krishnan A, Springer SA, Marcus R, Zaller N, Jordan AO, Lincoln T, Flanigan TP, Porterfield J, Altice FL. Contribution of Substance Use Disorders on HIV Treatment Outcomes and Antiretroviral Medication Adherence Among HIV-Infected Persons Entering Jail. AIDS And Behavior 2013, 17: 118-127. PMID: 23673792, PMCID: PMC3818019, DOI: 10.1007/s10461-013-0506-0.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAlcohol DrinkingAnti-Retroviral AgentsComorbidityCross-Sectional StudiesFemaleHIV InfectionsHumansLogistic ModelsMaleMedication AdherenceMiddle AgedPrisonersPrisonsSocioeconomic FactorsSubstance Abuse, IntravenousSubstance-Related DisordersTreatment OutcomeUnited StatesYoung AdultConceptsAntiretroviral medication adherenceSubstance use disordersMedication adherenceUse disordersEvidence-based drug treatmentHIV care providersHIV treatment engagementHIV treatment outcomesMedication-assisted therapyMulti-faceted interventionPaucity of evidenceDrug use severityAntiretroviral therapyPoor outcomePsychiatric comorbidityHIV treatmentTreatment outcomesDrug treatmentCare providersJail detaineesTreatment engagementUS sitesSubstance useVulnerable populationsUse severityIntegrating buprenorphine maintenance therapy into federally qualified health centers: Real-world substance abuse treatment outcomes
Haddad MS, Zelenev A, Altice FL. Integrating buprenorphine maintenance therapy into federally qualified health centers: Real-world substance abuse treatment outcomes. Drug And Alcohol Dependence 2013, 131: 127-135. PMID: 23332439, PMCID: PMC3674170, DOI: 10.1016/j.drugalcdep.2012.12.008.Peer-Reviewed Original ResearchConceptsQualified health centersSubstance abuse counselingHealth centersBuprenorphine maintenance treatment programCocaine useBuprenorphine maintenance therapyConcomitant cocaine useOpioid-dependent patientsMaintenance treatment programReal-world effectivenessSubstance abuse treatment outcomesElectronic health recordsHCV infectionMaintenance therapyPsychiatric comorbidityMean ageDependent patientsPsychiatric medicationsClinical trialsTreatment outcomesMood disordersFamily practitionersMore weeksTreatment programBMT
2011
Pharmacokinetic drug interactions and adverse consequences between psychotropic medications and pharmacotherapy for the treatment of opioid dependence
Saber-Tehrani AS, Bruce RD, Altice FL. Pharmacokinetic drug interactions and adverse consequences between psychotropic medications and pharmacotherapy for the treatment of opioid dependence. The American Journal Of Drug And Alcohol Abuse 2011, 37: 1-11. PMID: 21247284, DOI: 10.3109/00952990.2010.540279.Peer-Reviewed Original ResearchConceptsPharmacokinetic drug interactionsDrug interactionsOpioid dependencePsychotropic medicationsPsychoactive medicationsImportant pharmacokinetic drug interactionsClasses of medicationsOpioid-dependent patientsRelevant English-language articlesClinical case seriesMedication-assisted treatmentCytochrome P450 isoenzymesImportant clinical consequencesEnglish-language articlesPharmacokinetic interaction studyCase seriesPsychiatric comorbidityEmbase databasesClinical consequencesMedicationsP450 isoenzymesBuprenorphineMethadoneLanguage articlesPsychoactive drugs
2010
Treatment of medical, psychiatric, and substance-use comorbidities in people infected with HIV who use drugs
Altice FL, Kamarulzaman A, Soriano VV, Schechter M, Friedland GH. Treatment of medical, psychiatric, and substance-use comorbidities in people infected with HIV who use drugs. The Lancet 2010, 376: 367-387. PMID: 20650518, PMCID: PMC4855280, DOI: 10.1016/s0140-6736(10)60829-x.Peer-Reviewed Original ResearchMeSH KeywordsAIDS-Related Opportunistic InfectionsAnti-HIV AgentsAntipsychotic AgentsAntitubercular AgentsAntiviral AgentsBacterial InfectionsComorbidityCriminal LawDrug InteractionsDrug Resistance, BacterialEvidence-Based MedicineHepatitis, Viral, HumanHIV InfectionsHumansMedication AdherenceMental DisordersNarcoticsPrisonersSubstance-Related DisordersTuberculosisConceptsSubstance use disordersDrug usersAntiretroviral therapyViral hepatitisHIV treatmentHealth of HIVPharmacokinetic drug interactionsSubstance use comorbiditiesMedication-assisted therapyEvidence-based treatmentsDrug-resistant strainsHealth-related outcomesHealth service deliveryInfectious complicationsMultiple comorbiditiesHIV infectionPsychiatric comorbidityPoor adherenceClinical managementCardiovascular diseaseInadequate prescriptionCongregate settingsDrug interactionsComorbiditiesHIV