2023
Substance use and other correlates of HIV infection among transwomen and men who have sex with men in Perú: Implications for targeted HIV prevention strategies for transwomen
Cyrus E, Lama J, Sanchez J, Sullivan D, Leon S, Villaran M, Vagenas P, Vu D, Coudray M, Altice F. Substance use and other correlates of HIV infection among transwomen and men who have sex with men in Perú: Implications for targeted HIV prevention strategies for transwomen. PLOS Global Public Health 2023, 3: e0001464. PMID: 36962933, PMCID: PMC10022005, DOI: 10.1371/journal.pgph.0001464.Peer-Reviewed Original ResearchHIV risk factorsRisk factorsHIV riskSubstance usePrevention strategiesCross-sectional biobehavioral surveyHIV prevention strategiesTargeted prevention strategiesDifferent risk factorsSubstance use patternsBinary logistic regressionHIV infectionHIV prevalenceBiobehavioral surveysHigh prevalenceChi-square analysisSecondary data analysisHigh riskDrug useAlcohol dependenceCocaine useLogistic regressionMSMClinical researchRelated correlatesIntensified pulmonary tuberculosis case finding among HIV-infected new entrants of a prison in Malaysia: implications for a holistic approach to control tuberculosis in prisons
Al-Darraji H, Hill P, Sharples K, Altice F, Kamarulzaman A. Intensified pulmonary tuberculosis case finding among HIV-infected new entrants of a prison in Malaysia: implications for a holistic approach to control tuberculosis in prisons. International Journal Of Prisoner Health 2023, 19: 501-511. PMID: 36622107, DOI: 10.1108/ijph-01-2022-0001.Peer-Reviewed Original ResearchTB diseaseComprehensive TB control programMedian CD4 lymphocyte countGeneXpert MTB/RIFPrison entryCD4 lymphocyte countClinical scoring systemTB control programsPulmonary tuberculosis casesMTB/RIFMandatory HIV testingActive TBLymphocyte countTB casesConsented participantsHIV infectionHIV testingClinical presentationTuberculosis casesMean ageTuberculosis diseaseHigh prevalenceSputum samplesScoring systemHIV
2021
The Cooperative Re-Engagement Controlled trial (CoRECT): A randomised trial to assess a collaborative data to care model to improve HIV care continuum outcomes
Fanfair R, Khalil G, Williams T, Brady K, DeMaria A, Villanueva M, Randall L, Jenkins H, Altice F, Camp N, Lucas C, Buchelli M, Samandari T, Weidle P. The Cooperative Re-Engagement Controlled trial (CoRECT): A randomised trial to assess a collaborative data to care model to improve HIV care continuum outcomes. The Lancet Regional Health - Americas 2021, 3: 100057. PMID: 36777404, PMCID: PMC9903939, DOI: 10.1016/j.lana.2021.100057.Peer-Reviewed Original ResearchActive public health interventionMonths of randomizationViral load suppressionHIV viral loadPublic health interventionsViral loadCD4 countViral suppressionCare participantsCare strategiesHealth departmentsHealth interventionsDays of randomizationProportion of PWHStandard of careNon-Hispanic blacksHIV careContinuum outcomesHIV infectionMedian timeHIV transmissionCopies/Group overallClinic dataMedical careCorrelates of newly diagnosed HIV infection among cisgender women sex workers and transgender women sex workers in Greater Kuala Lumpur, Malaysia
Wang M, Lim SH, Gibson BA, Azwa I, Guadamuz TE, Altice FL, Kamarulzaman A, Wickersham JA. Correlates of newly diagnosed HIV infection among cisgender women sex workers and transgender women sex workers in Greater Kuala Lumpur, Malaysia. International Journal Of STD & AIDS 2021, 32: 609-619. PMID: 33752518, DOI: 10.1177/0956462420970417.Peer-Reviewed Original ResearchConceptsHIV infectionCisgender women sex workersWomen sex workersSex workersTransgender women sex workersMultivariable logistic regressionCondomless vaginal sexDetection of HIVUnique vulnerabilitiesHIV/Infection screeningHIVVaginal sexInfectionLogistic regressionEcstasy/MDMALower likelihoodLifetime useMost participantsKuala LumpurUnderstudied populationCorrelatesSex workers' experiencesPopulationChlamydiaWillingness to initiate pre-exposure prophylaxis (PrEP) and its use among opioid-dependent individuals in drug treatment
Ni Z, Altice FL, Wickersham JA, Copenhaver MM, DiDomizio EE, Nelson LE, Shrestha R. Willingness to initiate pre-exposure prophylaxis (PrEP) and its use among opioid-dependent individuals in drug treatment. Drug And Alcohol Dependence 2021, 219: 108477. PMID: 33422864, PMCID: PMC7946167, DOI: 10.1016/j.drugalcdep.2020.108477.Peer-Reviewed Original ResearchConceptsOpioid-dependent individualsPre-exposure prophylaxisPrEP useHIV riskHealthcare providersSex-related risk behaviorsMultivariable logistic regression analysisAwareness of PrEPUrban methadone clinicMultiple logistic regressionDisproportionate HIV burdenLogistic regression analysisCross-sectional surveyHIV burdenHIV infectionHIV testingIndependent correlatesMethadone clinicsDrug treatmentRisk behaviorsLogistic regressionPrEPPrevious useHigher likelihoodProphylaxis
2020
Willingness to Use HIV Self-Testing and Associated Factors Among Transgender Women in Malaysia
Shrestha R, Galka JM, Azwa I, Lim SH, Guadamuz TE, Altice FL, Wickersham JA. Willingness to Use HIV Self-Testing and Associated Factors Among Transgender Women in Malaysia. Transgender Health 2020, 5: 182-190. PMID: 32923668, PMCID: PMC7480722, DOI: 10.1089/trgh.2019.0085.Peer-Reviewed Original ResearchTransgender womenSex work clientsKey populationsMultivariable logistic regressionImplementation of HIVHIV Self-TestingCurrent depressive symptomsCross-sectional surveyCorrelates of willingnessHIV screeningHIV infectionMultivariable analysisAssociated FactorsDirect referralCondomless sexHigh riskDepressive symptomsHIVSTLogistic regressionCommunity-based organizationsWomenAdditional researchStaff membersParticipantsSelf-TestingIntegrating HIV pre‐exposure prophylaxis and harm reduction among men who have sex with men and transgender women to address intersecting harms associated with stimulant use: a modelling study
Bórquez A, Rich K, Farrell M, Degenhardt L, McKetin R, Tran LT, Cepeda J, Silva‐Santisteban A, Konda K, Cáceres CF, Kelly S, Altice FL, Martin NK. Integrating HIV pre‐exposure prophylaxis and harm reduction among men who have sex with men and transgender women to address intersecting harms associated with stimulant use: a modelling study. Journal Of The International AIDS Society 2020, 23: e25495. PMID: 32562365, PMCID: PMC7305413, DOI: 10.1002/jia2.25495.Peer-Reviewed Original ResearchConceptsMSM/transgender womenHIV pre-exposure prophylaxisPre-exposure prophylaxisNew HIV infectionsHIV infectionTransgender womenStimulant useCVD mortalityCVD deathHealth harmsIntegrated substance useMore HIV infectionsHigh HIV incidenceCardiovascular disease mortalityRandom allocationUnprotected anal sexRisk of suicideHIV incidenceHIV transmissionDisease mortalityHIV riskGlobal systematic reviewAnal sexReduction interventionsSystematic review
2019
Effect of expanding opioid agonist therapies on the HIV epidemic and mortality in Ukraine: a modelling study
Tan J, Altice FL, Madden LM, Zelenev A. Effect of expanding opioid agonist therapies on the HIV epidemic and mortality in Ukraine: a modelling study. The Lancet HIV 2019, 7: e121-e128. PMID: 31879250, PMCID: PMC7289179, DOI: 10.1016/s2352-3018(19)30373-x.Peer-Reviewed Original ResearchConceptsOpioid agonist therapyNew HIV infectionsHigh HIV burdenHIV infectionMinistry of HealthOAT coverageAgonist therapyHIV burdenHIV incidenceBuprenorphine maintenance therapyPublic Health CenterMaintenance therapyHIV outcomesHIV prevalenceHIV transmissionMedication procurementHIV epidemicHealth centersHIV preventionTreatment goalsPWIDOAT expansionDisease controlSexual riskInfectionEstimated Impact of Targeted Pre-Exposure Prophylaxis: Strategies for Men Who Have Sex with Men in the United States
Elion RA, Kabiri M, Mayer KH, Wohl DA, Cohen J, Beaubrun AC, Altice FL. Estimated Impact of Targeted Pre-Exposure Prophylaxis: Strategies for Men Who Have Sex with Men in the United States. International Journal Of Environmental Research And Public Health 2019, 16: 1592. PMID: 31067679, PMCID: PMC6539923, DOI: 10.3390/ijerph16091592.Peer-Reviewed Original ResearchConceptsYoung Latino MSMYoung Black MSMPre-exposure prophylaxisBlack MSMLatino MSMPrEP useHIV Incidence Risk IndexHuman immunodeficiency virus (HIV) transmissionUse of PrEPNon-PrEP usersLowest NNTHIV infectionNNT valuesHIV prevalenceHIV epidemicHIV preventionMSM populationSubsequent infectionInfection reductionMSMPrevalenceIncidenceVirus transmissionPrEPProphylaxis
2018
The Impact of Housing and HIV Treatment on Health-Related Quality of Life Among People With HIV Experiencing Homelessness or Unstable Housing
Giordano TP, Gallagher K, Davich JAW, Rathore M, Borne D, Davies E, Altice FL, Cabral H. The Impact of Housing and HIV Treatment on Health-Related Quality of Life Among People With HIV Experiencing Homelessness or Unstable Housing. American Journal Of Public Health 2018, 108: s531-s538. PMID: 32941776, PMCID: PMC6290581, DOI: 10.2105/ajph.2018.304731.Peer-Reviewed Original ResearchPhysical component summary scoreComponent summary scoresHIV suppressionCD4 countHIV treatmentSummary scoresPatient-centred comprehensive careCD4 cell countProspective cohort studyMental component scoreHealth-related qualityQuality of lifeHousing statusMental health needsCohort studyHIV infectionClinical parametersComprehensive careHigh prevalenceCell countHealth needsUS sitesUnstable housingHigher PCSCubic millimeter
2017
Cohort profile: seek, test, treat and retain United States criminal justice cohort
Chandler R, Gordon MS, Kruszka B, Strand LN, Altice FL, Beckwith CG, Biggs ML, Cunningham W, Chris Delaney JA, Flynn PM, Golin CE, Knight K, Kral AH, Kuo I, Lorvick J, Nance RM, Ouellet LJ, Rich JD, Sacks S, Seal D, Spaulding A, Springer SA, Taxman F, Wohl D, Young JD, Young R, Crane HM. Cohort profile: seek, test, treat and retain United States criminal justice cohort. Substance Abuse Treatment, Prevention, And Policy 2017, 12: 24. PMID: 28511680, PMCID: PMC5433052, DOI: 10.1186/s13011-017-0107-4.Peer-Reviewed Original ResearchConceptsHIV risk behaviorsTreatment cascadeViral loadHIV RNA viral loadCD4 T-cell countRisk behaviorsSubstance useT-cell countsHepatitis C infectionRNA viral loadInjection drug useHealth Related QualityHIV treatment cascadeUnprotected sexual intercourseHealth care accessRecent polysubstance useC infectionViral suppressionHIV diagnosisHIV infectionMedian ageRelated qualityCriminal justice involvementART treatmentCohort membersPredictors of mortality within prison and after release among persons living with HIV in Indonesia
Culbert GJ, Crawford FW, Murni A, Waluyo A, Bazazi AR, Sahar J, Altice FL. Predictors of mortality within prison and after release among persons living with HIV in Indonesia. Research And Reports In Tropical Medicine 2017, Volume 8: 25-35. PMID: 29238241, PMCID: PMC5724785, DOI: 10.2147/rrtm.s126131.Peer-Reviewed Original ResearchAntiretroviral therapyCrude mortality rateOpportunistic infectionsMortality rateCox proportional hazards regression modelProportional hazards regression modelsAdvanced HIV infectionPredictors of mortalityHazards regression modelsCommon probable causesIndonesian prisonersCause mortalityHIV infectionImmediate family membersOverall mortalityMortality predictorsHIV treatmentKaplan-MeierSurvival overallLonger survivalMedical recordsImmune functionHIVMortalityAddiction treatmentA Qualitative Assessment of Alcohol Consumption and Sexual Risk Behaviors Among Men Who Have Sex With Men and Transgender Women in Peru
Vagenas P, Brown SE, Clark JL, Konda KA, Lama JR, Sánchez J, Duerr AC, Altice FL. A Qualitative Assessment of Alcohol Consumption and Sexual Risk Behaviors Among Men Who Have Sex With Men and Transgender Women in Peru. Substance Use & Misuse 2017, 52: 831-839. PMID: 28426357, PMCID: PMC5595368, DOI: 10.1080/10826084.2016.1264968.Peer-Reviewed Original ResearchConceptsAlcohol use disorderMSM/transgender womenTransgender womenAlcohol consumptionRisk behaviorsRisky sexual behaviorConcentrated HIV epidemicMultiple sexual partnersSexual behaviorSexual risk behaviorsAntiretroviral therapyHIV infectionHIV incidenceHIV transmissionMedication adherenceProblematic drinkingSemi-structured focus groupsHIV epidemicHigh prevalencePharmacological interventionsUse disordersFocus groupsUnprotected sexAlcohol dependencePeruvian men
2016
Willingness to Use Pre-Exposure Prophylaxis (PrEP): An Empirical Test of the Information-Motivation-Behavioral Skills (IMB) Model among High-Risk Drug Users in Treatment
Shrestha R, Altice FL, Huedo-Medina TB, Karki P, Copenhaver M. Willingness to Use Pre-Exposure Prophylaxis (PrEP): An Empirical Test of the Information-Motivation-Behavioral Skills (IMB) Model among High-Risk Drug Users in Treatment. AIDS And Behavior 2016, 21: 1299-1308. PMID: 27990587, PMCID: PMC5380590, DOI: 10.1007/s10461-016-1650-0.Peer-Reviewed Original ResearchConceptsHigh-risk PWUDBehavioral skills modelCommunity-based methadone maintenance treatmentPre-exposure prophylaxis trialsSex-related HIV risk behaviorsHigh-risk drug usersPre-exposure prophylaxisIMB modelMethadone maintenance treatmentEfficacy of PrEPUse of PrEPHIV risk behaviorsKey risk populationsHealth behavior changeHIV acquisitionProphylaxis trialsHIV infectionMaintenance treatmentHIV preventionRisk populationsDrug usersRisk behaviorsPrEPPWUDIntervention developmentThe perfect storm: incarceration and the high-risk environment perpetuating transmission of HIV, hepatitis C virus, and tuberculosis in Eastern Europe and Central Asia
Altice FL, Azbel L, Stone J, Brooks-Pollock E, Smyrnov P, Dvoriak S, Taxman FS, El-Bassel N, Martin NK, Booth R, Stöver H, Dolan K, Vickerman P. The perfect storm: incarceration and the high-risk environment perpetuating transmission of HIV, hepatitis C virus, and tuberculosis in Eastern Europe and Central Asia. The Lancet 2016, 388: 1228-1248. PMID: 27427455, PMCID: PMC5087988, DOI: 10.1016/s0140-6736(16)30856-x.Peer-Reviewed Original ResearchConceptsOpioid agonist therapyHepatitis C virusIncident tuberculosis casesAgonist therapyC virusTuberculosis casesHIV transmissionEECA countriesAntiretroviral therapy coverageHIV transmission riskNew HIV infectionsInjection of opioidsTransmission of HIVSecondary preventionHIV infectionHIV incidenceSyringe programsHIVDrug useLarge burdenTransmission riskTherapyTuberculosisDrugsHigh levelsIntersecting epidemics of HIV, HCV, and syphilis among soon-to-be released prisoners in Kyrgyzstan: Implications for prevention and treatment
Azbel L, Polonsky M, Wegman M, Shumskaya N, Kurmanalieva A, Asanov A, Wickersham JA, Dvoriak S, Altice FL. Intersecting epidemics of HIV, HCV, and syphilis among soon-to-be released prisoners in Kyrgyzstan: Implications for prevention and treatment. International Journal Of Drug Policy 2016, 37: 9-20. PMID: 27455177, PMCID: PMC5124506, DOI: 10.1016/j.drugpo.2016.06.007.Peer-Reviewed Original ResearchConceptsDrug injectionHIV infectionLifetime drug injectionPrison drug injectionHIV care continuumAntiretroviral therapy coverageConfidence intervalsMean numberEpidemic of HIVHealth assessment surveyUndiagnosed syphilisSyphilis infectionConsented participantsHIV incidenceHIV transmissionIndependent correlatesWeighted prevalenceEvidence-based responsesHIV epidemicCare continuumDuration of imprisonmentHIV preventionHealth SurveyAIDS mortalityHIVUndiagnosed pulmonary tuberculosis among prisoners in Malaysia: an overlooked risk for tuberculosis in the community
Al-Darraji HA, Altice FL, Kamarulzaman A. Undiagnosed pulmonary tuberculosis among prisoners in Malaysia: an overlooked risk for tuberculosis in the community. Tropical Medicine And International Health 2016, 21: 1049-1058. PMID: 27197601, DOI: 10.1111/tmi.12726.Peer-Reviewed Original ResearchGeneXpert MTB/RIFCase-finding strategyActive TBMTB/RIFTB treatmentMalaysia's largest prisonUndiagnosed pulmonary tuberculosisActive tuberculosis casesOlder age groupsLargest prisonPulmonary tuberculosisHIV infectionTuberculosis casesHigh prevalenceSputum samplesSmear microscopyClinical informationAverage ageCulture resultsAge groupsScreening studyComplete dataHIVRegression analysisTuberculosis
2015
Correlates of retention on extended-release naltrexone among persons living with HIV infection transitioning to the community from the criminal justice system
Springer SA, Brown SE, Di Paola A, Altice FL. Correlates of retention on extended-release naltrexone among persons living with HIV infection transitioning to the community from the criminal justice system. Drug And Alcohol Dependence 2015, 157: 158-165. PMID: 26560326, PMCID: PMC4675147, DOI: 10.1016/j.drugalcdep.2015.10.023.Peer-Reviewed Original ResearchConceptsAlcohol use disorderExtended-release naltrexoneOpioid use disorderXR-NTXUse disordersHIV diseaseFirst injectionDouble-blind placebo-controlled randomized trialSecond injectionPlacebo-controlled randomized trialSubstance use disordersMultivariate regression analysisTreatment of alcoholCorrelates of retentionAntiretroviral therapyStudy drugHIV infectionRandomized trialsUrine testsUrine screensEligible personsDays of releaseHazardous drinkingCocaine useDemographic featuresDrug Treatment as HIV Prevention Among Women and Girls Who Inject Drugs From a Global Perspective
Springer SA, Larney S, Alam-mehrjerdi Z, Altice FL, Metzger D, Shoptaw S. Drug Treatment as HIV Prevention Among Women and Girls Who Inject Drugs From a Global Perspective. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2015, 69: s155-s161. PMID: 25978482, PMCID: PMC4443704, DOI: 10.1097/qai.0000000000000637.Peer-Reviewed Original ResearchConceptsMedication-assisted therapyDrug treatmentAntiretroviral therapyHIV transmission riskNew HIV infectionsHarm reduction servicesSubstance use disordersPoor treatment accessImplementation of interventionsOpioid useHIV infectionEvidence-based practiceHIV preventionOpioid addictionTreatment accessUse disordersReduction servicesSexual riskTransmission riskTherapyWomenTreatmentDrugsImpressive lackSignificant reductionCost-Effectiveness Analysis of Brief and Expanded Evidence-Based Risk Reduction Interventions for HIV-Infected People Who Inject Drugs in the United States
Song DL, Altice FL, Copenhaver MM, Long EF. Cost-Effectiveness Analysis of Brief and Expanded Evidence-Based Risk Reduction Interventions for HIV-Infected People Who Inject Drugs in the United States. PLOS ONE 2015, 10: e0116694. PMID: 25658949, PMCID: PMC4320073, DOI: 10.1371/journal.pone.0116694.Peer-Reviewed Original ResearchConceptsQuality-adjusted life yearsOpioid substitution therapyHIV infectionHIV incidenceHIV prevalenceEvidence-based risk reduction interventionDynamic HIV transmission modelHolistic Health Recovery ProgramBehavioral HIV prevention interventionsFuture HIV incidenceTotal medical costsHIV transmission modelHIV prevention interventionsGeneral adult populationRisk reduction interventionsCost-effectiveness analysisSubstitution therapySexual transmissionHIV programsPrevention interventionsMedical costsTreatment settingsLife yearsReduction interventionsUS population