Wei Wei, PhD

Assistant Professor of Medicine (Medical Oncology)

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Appointments

Medical Oncology and Hematology

Primary

Additional Titles

Interim Director of Biostatistics Shared Resource, Yale Cancer Center

Contact Info

wei.wei@yale.edu

About

Titles

Assistant Professor of Medicine (Medical Oncology)

Interim Director of Biostatistics Shared Resource, Yale Cancer Center

Biography

Wei Wei is an Assistant Professor in the Department of Biostatistics at the Yale School of Public Health. Dr. Wei's research area focuses on development of early phase clinical trial designs, with particular interest in cancer targeted and immunotherapeutic agents.

Last Updated on October 04, 2025.

Appointments

Medical Oncology and Hematology
Assistant Professor
Primary

Internal Medicine
Medical Oncology and Hematology
Yale Cancer Center

Education & Training

PhD: Medical University of South Carolina, Biostatistics (2016)

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Research

Overview

Public Health Interests

Clinical Trials; Biomarkers; Cancer

ORCID
0000-0003-1263-5620

Research at a Glance

Yale Co-Authors

Frequent collaborators of Wei Wei's published research.

Harriet Kluger, MD
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View 17 Common Publications
David Rimm, MD, PhD
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View 12 Common Publications
Amit Mahajan, MD
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View 6 Common Publications
Jan Philipp Bewersdorf, MD, FACP
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View 6 Common Publications
Nikolai Podoltsev, MD, PhD
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View 6 Common Publications
Daniel Zelterman, PhD
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View 5 Common Publications

Publications

2025

Fruquintinib in less pretreated patients: Multivariate profile-matching analysis of FRESCO-2 to FRESCO.
Dasari A, Eng C, Lonardi S, Garcia-Carbonero R, Masuishi T, Cremolini C, Ghiringhelli F, Hubbard J, Bekaii-Saab T, Jones J, Xu RH, Shen L, Xu J, Bai Y, Deng Y, Yuan Y, Wei W, Lin J, Chen L, Yang Z, Schelman WR, Qin S, Li J. Fruquintinib in less pretreated patients: Multivariate profile-matching analysis of FRESCO-2 to FRESCO. Eur J Cancer 2025, 227: 115641. PMID: 40795524, DOI: 10.1016/j.ejca.2025.115641.
Peer-Reviewed Original Research
Clinical, sociodemographic, and facility-related determinants of immunotherapy use in metastatic triple-negative breast cancer
Ajjawi I, Rios A, Wei W, Park TS, Lustberg MB. Clinical, sociodemographic, and facility-related determinants of immunotherapy use in metastatic triple-negative breast cancer. Breast Cancer Res Treat. 2025 Jul;212(2):299-308. doi: 10.1007/s10549-025-07725-3. Epub 2025 May 15. PMID: 40369346.
Peer-Reviewed Original Research
Clinical, Sociodemographic, and Facility-Related Factors Influencing HER2-Targeted Therapy in Metastatic Hormone Receptor-Negative, HER2-Positive Breast Cancer
Ajjawi I, Rios A, Wei W, Park TS, Lustberg MB. Clinical, Sociodemographic, and Facility-Related Factors Influencing HER2-Targeted Therapy in Metastatic Hormone Receptor-Negative, HER2-Positive Breast Cancer. Cancers (Basel). 2025 May 6;17(9):1579. doi: 10.3390/cancers17091579. PMID: 40361505; PMCID: PMC12072055.
Peer-Reviewed Original Research
Phase II Trial of Chemotherapy, Cetuximab, and Erlotinib in Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck
Bhatia A, Mehra R, Bauman J, Khan S, Wei W, Neumeister V, Sandoval‐Schaefer T, Alpaugh R, Lango M, Rimm D, Ridge J, Burtness B. Phase II Trial of Chemotherapy, Cetuximab, and Erlotinib in Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck. Head & Neck 2025, 47: 2373-2382. PMID: 40166973, DOI: 10.1002/hed.28152.
Peer-Reviewed Original Research
This study investigates the efficacy of adding erlotinib to chemotherapy and cetuximab for head and neck cancer, showing improved response rates, highlighting potential for dual EGFR targeting in treatment.
Full Summary
Phase II Trial of Pembrolizumab in Combination With Bevacizumab for Untreated Melanoma Brain Metastases
Weiss S, Djureinovic D, Wei W, Tran T, Austin M, Markowitz J, Eroglu Z, Khushalani N, Hegde U, Cohen J, Sznol M, Anderson G, Johnson B, Piteo C, Mahajan A, Adeniran A, Jilaveanu L, Goldberg S, Chiang V, Forsyth P, Kluger H. Phase II Trial of Pembrolizumab in Combination With Bevacizumab for Untreated Melanoma Brain Metastases. Journal Of Clinical Oncology 2025, 43: 1685-1694. PMID: 40048689, PMCID: PMC12058415, DOI: 10.1200/jco-24-02219.
Peer-Reviewed Original Research
Concepts
Statistical considerations for evaluating treatment effect under various non-proportional hazard scenarios
Zhang X, Greene E, Blaha O, Wei W. Statistical considerations for evaluating treatment effect under various non-proportional hazard scenarios. Statistical Methods In Medical Research 2025, 34: 986-1000. PMID: 39930911, DOI: 10.1177/09622802241313297.
Peer-Reviewed Original Research
Concepts
Bayesian model averaging for randomized dose optimization trials in multiple indications.
Wei W, Lin J. Bayesian model averaging for randomized dose optimization trials in multiple indications. J Biopharm Stat 2025, 1-13. PMID: 39930766, DOI: 10.1080/10543406.2025.2450325.
Peer-Reviewed Original Research

2024

See All Publications

Academic Achievements & Community Involvement

Activities

activity
Leukemia & Lymphoma Society
2025 - PresentPeer Review Groups and Grant Study SectionsGrant Reviewer
activity
Design and Implementation of Clinical Trials
11/17/2025 - 11/21/2025LectureWinn-AACR Design and Implementation of Clinical Trials Workshop
Details
Albuquerque, NM, United StatesSponsored by American Association for Cancer Research
Collaborators
Yu ShyrVanderbilt University Medical Center

Teaching & Mentoring

Mentoring

Jinping Liang
Graduate student
2025 - Present
Michelle Song
Graduate student
2025 - Present
Yunhe Liu
Graduate student at YSPH
2022 - 2024
Yunxuan Zhang
Graduate student at YSPH
2022 - 2023

Willing and Available to Mentor
- Students

News

Get In Touch

Contacts

wei.wei@yale.edu

Appointments

Additional Titles

Contact Info

Titles

Biography

Appointments

Medical Oncology and Hematology

Other Departments & Organizations

Education & Training

Overview

Public Health Interests

ORCID

Research at a Glance

Yale Co-Authors

Harriet Kluger, MD

David Rimm, MD, PhD

Amit Mahajan, MD

Jan Philipp Bewersdorf, MD, FACP

Nikolai Podoltsev, MD, PhD

Daniel Zelterman, PhD

Publications

2025

2024

Bayesian model averaging for dose optimization in multiple indications.

Activities

Leukemia & Lymphoma Society

Design and Implementation of Clinical Trials

Mentoring

Jinping Liang

Michelle Song

Yunhe Liu

Yunxuan Zhang

Willing and Available to Mentor

News

Unexpected Findings in Study of T Cells, Considered Front-line Fighters Against Advanced Melanoma

Discoveries & Impact (August 2022)

Contacts