Mary Savoye, RD
Associate Director, Pediatric Obesity and Director, Bright Bodies ProgramCards
About
Research
Publications
2024
Improving access to first‐line treatment for pediatric obesity: Lessons from the dissemination of SmartMoves
Finn E, Keller C, Gowey M, Savoye M, Samuels S, Fleisch A, Rogers V, Grey M, Damschroder L, Beck A, Sharifi M. Improving access to first‐line treatment for pediatric obesity: Lessons from the dissemination of SmartMoves. Obesity 2024, 32: 1745-1756. PMID: 39192771, DOI: 10.1002/oby.24107.Peer-Reviewed Original ResearchConceptsConstant comparative methodInterviewed key informantsHealth behaviorsObesity programsSufficient staffingInsufficient staffingPediatric obesityFunding insecurityLifestyle treatmentImprove accessOrganizational prioritiesProgram componentsProgram fitPromote fidelityKey informantsUS sitesIncreased prevalenceAdequate fundingSurvey findingsStaffingParticipantsInterviewsCOVID-19 pandemicDominant barriersObesityLow‐calorie diet‐induced weight loss is associated with altered brain connectivity and food desire in obesity
Hoang H, Lacadie C, Hwang J, Lam K, Elshafie A, Rosenberg S, Watt C, Sinha R, Constable R, Savoye M, Seo D, Belfort‐DeAguiar R. Low‐calorie diet‐induced weight loss is associated with altered brain connectivity and food desire in obesity. Obesity 2024, 32: 1362-1372. PMID: 38831482, PMCID: PMC11211061, DOI: 10.1002/oby.24046.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingIntrinsic connectivity distributionDiet-induced weight lossBrain connectivityAssociated with altered brain connectivityLow-calorie dietEating behavior changesShort-term low-calorie dietRight hippocampusTemporal cortexBrain networksWeight lossBrain clustersEffects of diet-induced weight lossGroup differencesFood desireGlucose levelsDiagnosis of type 2 diabetesBehavioral changesMagnetic resonance imagingType 2 diabetesBrainLeptin levelsFood intakeResonance imaging
2014
Reversal of Early Abnormalities in Glucose Metabolism in Obese Youth: Results of an Intensive Lifestyle Randomized Controlled Trial
Savoye M, Caprio S, Dziura J, Camp A, Germain G, Summers C, Li F, Shaw M, Nowicka P, Kursawe R, DePourcq F, Kim G, Tamborlane WV. Reversal of Early Abnormalities in Glucose Metabolism in Obese Youth: Results of an Intensive Lifestyle Randomized Controlled Trial. Diabetes Care 2014, 37: 317-324. PMID: 24062325, PMCID: PMC3898759, DOI: 10.2337/dc13-1571.Peer-Reviewed Original ResearchConceptsStandard of careClinical careBlood glucoseObese adolescentsObese youthOral glucose tolerance test glucoseIntensive lifestyle modificationDiabetes Prevention ProgramStandard clinical careInsulin sensitivity indexHealthy lifestyle programType 2 diabetesRisk of T2DChildhood obesity epidemicΒ-cell dysfunctionLifestyle modificationControlled TrialsOGTT glucosePrimary outcomeGlucose toleranceInsulin resistanceLifestyle programAnthropometric assessmentEarly abnormalitiesGlucose levels
2012
Preventing Diabetes among Fair Haven Families: A Community-Based Approach to Quality Improvement
Chakkalakal RJ, Camp AW, Magenheimer E, Savoye M, Lubsen J, Lucas G, Rosenthal MS. Preventing Diabetes among Fair Haven Families: A Community-Based Approach to Quality Improvement. Journal Of Health Care For The Poor And Underserved 2012, 23: 247-254. PMID: 22864501, DOI: 10.1353/hpu.2012.0136.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultChildCommunity Health CentersCommunity-Based Participatory ResearchConnecticutDiabetes Mellitus, Type 2Evidence-Based PracticeFamilyFemaleHispanic or LatinoHumansLife StyleMedically Underserved AreaMiddle AgedObesityQuality Assurance, Health CareSocial SupportWeight Reduction ProgramsYoung AdultHepatic Fat Accumulation Is Modulated by the Interaction between the rs738409 Variant in the PNPLA3 Gene and the Dietary Omega6/Omega3 PUFA Intake
Santoro N, Savoye M, Kim G, Marotto K, Shaw MM, Pierpont B, Caprio S. Hepatic Fat Accumulation Is Modulated by the Interaction between the rs738409 Variant in the PNPLA3 Gene and the Dietary Omega6/Omega3 PUFA Intake. PLOS ONE 2012, 7: e37827. PMID: 22629460, PMCID: PMC3357343, DOI: 10.1371/journal.pone.0037827.Peer-Reviewed Original ResearchConceptsALT levelsObese youthSingle nucleotide polymorphismsRs738409 single nucleotide polymorphismFatty acid intakeFatty liver developmentLiver fat contentHepatic fat accumulationNutrition Data SystemRs738409 variantPNPLA3 genotypePUFA intakeFatty liverAcid intakeHepatic steatosisHepatic fatLiver damageDietary factorsFat accumulationPNPLA3 geneMRI studiesG alleleALT measurementsPUFA ratioPotential role
2011
Long-term Results of an Obesity Program in an Ethnically Diverse Pediatric Population
Savoye M, Nowicka P, Shaw M, Yu S, Dziura J, Chavent G, O'Malley G, Serrecchia JB, Tamborlane WV, Caprio S. Long-term Results of an Obesity Program in an Ethnically Diverse Pediatric Population. Pediatrics 2011, 127: 402-410. PMID: 21300674, PMCID: PMC3065145, DOI: 10.1542/peds.2010-0697.Peer-Reviewed Original ResearchConceptsControl groupLow-density lipoprotein cholesterolTotal body fat massIntensive lifestyle programIntensive lifestyle interventionHomeostasis model assessmentActive intervention phaseWeight management programBody fat massLong-term resultsBMI z-scorePercent body fatDiverse pediatric populationFamily-based programsLifestyle interventionLipoprotein cholesterolTotal cholesterolObese childrenObese populationPediatric populationInsulin resistanceObesity programLifestyle programFat massIntervention group
2009
Glucose dysregulation and hepatic steatosis in obese adolescents: Is there a link?
Cali AM, De Oliveira AM, Kim H, Chen S, Reyes‐Mugica M, Escalera S, Dziura J, Taksali SE, Kursawe R, Shaw M, Savoye M, Pierpont B, Constable RT, Caprio S. Glucose dysregulation and hepatic steatosis in obese adolescents: Is there a link? Hepatology 2009, 49: 1896-1903. PMID: 19434725, PMCID: PMC2692562, DOI: 10.1002/hep.22858.Peer-Reviewed Original ResearchConceptsHepatic fat fractionObese adolescentsHepatic fat contentGlucose dysregulationHepatic steatosisMetabolic syndromeFatty liverInsulin sensitivityTotal fatHigher hepatic fat fractionStandard oral glucose tolerance testOral glucose tolerance testTwo-hour plasma glucoseSubcutaneous fat ratioHomeostasis model assessmentAbdominal fat distributionGlucose tolerance testProinflammatory milieuHMW adiponectinIL-6Insulin resistanceMatsuda indexTolerance testPlasma glucoseFat distribution
Others
- Nowicka P, Savoye M. Strategies that motivate children and their families to take positive action: Empowering self efficacy and change. Int J Ped Obesity 5(Suppl 1): 25-27, 2010.Peer-Reviewed Original Research
Clinical Trials
Current Trials
The Role of Hepatic De Novo Lipogenesis (DNL) in the Pathogenesis of Hepatic Steatosis
HIC ID1604017607RoleSub InvestigatorPrimary Completion Date05/01/2023Recruiting ParticipantsGenderBothAge12 years - 30 yearsPrevalence of Carbohydrate Intolerance in Lean and Obese Children
HIC ID9909011190RoleSub InvestigatorPrimary Completion Date09/30/2025Recruiting ParticipantsGenderBothAge8 years - 18 years
Academic Achievements & Community Involvement
Clinical Care
Overview
Mary Savoye is dietitian who specializes in obesity and Type 2 diabetes in both children and adults. She has 25 years of experience in these fields at Yale.
As a clinical dietitian, Savoye educates patients on how to improve their diet and make lifestyle changes—like eating healthy food, exercising, and reducing stress—that can help manage their conditions. With a background in mental health counseling, she provides support and guidance for overcoming obesity-related habits and making permanent lifestyle changes.
She founded and directs Bright Bodies, a weight management program for children who meet weekly to learn how to make better food choices and become aware of their triggers for overeating. This curriculum- and evidence-based program is also being used nationally and internationally.
“Seeing the smile on children’s faces during group counseling sessions makes it all worthwhile,” Savoye says.
Savoye chose her specialty because she struggled with weight problems as a teenager. “I’ve seen firsthand what being overweight can do to a child's self-esteem and how dieting can worsen the problem,” Savoye says.
Ms. Savoye is also a certified diabetes counselor and understands the challenges her Type 2 diabetes patients face because her family members are prone to developing the condition. She is the author of a book entitled, “The 1 Thing Diet.”
“I tell patients they can make a difference in their lives and that they are not alone,” she says. “We are here to support them at every step along the way.”
Savoye is also involved in research in the fields of obesity and Type 2 diabetes in children and adults. Her work has been published in several journals including the Journal of the American Medical Association, Diabetes Care, Pediatrics, and the International Journal of Pediatrics.
Clinical Specialties
Board Certifications
Certified Dietitian
- Certification Organization
- American Dietetic Association
- Original Certification Date
- 2004
Diabetes Educator
- Certification Organization
- National Certification Board for Diabetes Educators
- Latest Certification Date
- 2017
- Original Certification Date
- 1997
News
News
- November 01, 2023
Stigma adds fuel to the obesity epidemic
- April 25, 2023Source: Mother Jones
Should Insurers Cover Kids’ Obesity Drugs? Experts Say It’s Long Overdue.
- February 21, 2023Source: Yale News
Insights & Outcomes: Clinical trial data gaps and a universe of old milk
- February 06, 2022Source: CT-HIT
Lockdowns, Remote Learning Contribute To Surge In Childhood Obesity