Dendritic Spine Remodeling After Spinal Cord Injury Alters Neuronal Signal Processing
Tan AM, Choi JS, Waxman SG, Hains BC. Dendritic Spine Remodeling After Spinal Cord Injury Alters Neuronal Signal Processing. Journal Of Neurophysiology 2009, 102: 2396-2409. PMID: 19692517, DOI: 10.1152/jn.00095.2009.Peer-Reviewed Original ResearchConceptsSpinal cord injuryCord injurySynaptic transmissionDorsal horn nociceptive neuronsFrequency-following abilityDendritic spine remodelingGeneration of painAction potential activationDendritic spine morphologyDendritic spine shapeAbnormal painCentral sensitizationNociceptive neuronsSpine remodelingPostsynaptic neuronsDendritic spinesSpine morphologyInput-output functionPainSoma resultsInjurySpine shapeNeuronal statesNeuronsPotential activation