2022
Dendritic Spines and Pain Memory
Benson C, King J, Reimer M, Kauer S, Waxman S, Tan A. Dendritic Spines and Pain Memory. The Neuroscientist 2022, 30: 294-314. PMID: 36461773, DOI: 10.1177/10738584221138251.Peer-Reviewed Original ResearchNeuropathic painDendritic spinesSynaptic transmissionSpinal cord dorsal hornForm of painNew therapeutic approachesSurface of neuronsDorsal hornIntractable painDeep laminaePain memoryTherapeutic approachesPainNervous systemNew therapeuticsSpineMillions of peopleInjuryDiseaseRecent studiesReview articlePrevalenceNeuronsImportant role
2011
Spinal cord injury, dendritic spine remodeling, and spinal memory mechanisms
Tan AM, Waxman SG. Spinal cord injury, dendritic spine remodeling, and spinal memory mechanisms. Experimental Neurology 2011, 235: 142-151. PMID: 21925174, DOI: 10.1016/j.expneurol.2011.08.026.Peer-Reviewed Original ResearchConceptsSpinal cord injuryNeuropathic painDendritic spinesChronic painCord injuryNervous systemWide dynamic range neuronsNociceptive dorsal horn neuronsDorsal horn neuronsDendritic spine remodelingRange neuronsCentral sensitizationSpinal cordSpine remodelingPainSynaptic potentiationPain researchInjuryMore effective strategiesAberrant changesLong-term memory storageSpineStructural substrateSynaptic modelNeurons