Neuromuscular Diseases
- Antigen-specific immune therapy (CNP-106) for treatment of generalised myasthenia gravis: rationale and design of first-in-human randomised controlled trial.G Brew S, Frey M, P McCarthy D, Elhofy A, Nowak RJ. BMJ Neurol Open. 2024; 2024 Dec 18. PMID: 39720510.
- Application of digital tools and artificial intelligence in the Myasthenia Gravis Core Examination.Garbey M, Lesport Q, Girma H, Öztosun G, Abu-Rub M, Guidon AC, Juel V, Nowak RJ, Soliven B, Aban I, Kaminski HJ. Front Neurol. 2024; 2024 Dec 4. PMID: 39697445.
- US Clinical Practice Experience with Eculizumab in Myasthenia Gravis: Acute Clinical Events and Healthcare Resource Utilization.Nowak RJ, Habib AA, Klink AJ, Muppidi S, Parthan A, Sader SC, Balanean A, Gajra A, Howard JF Jr. Drugs Real World Outcomes. 2024 Dec; 2024 Oct 29. PMID: 39470958.
- CMT2 and distal hereditary motor neuropathy associated with VRK1 variants: Case series.Živković SA, Nowak RJ, DiCapua D. Neuromuscul Disord. 2024 Nov 29; 2024 Nov 29. PMID: 39693713.
- Fluorescence-detection size-exclusion chromatography specifically detects autoantibodies targeting the ganglionic acetylcholine receptor in patients with autoimmune autonomic ganglionopathy.Baxter L, Hopkins S, O'Connor KC, Pham MC, Nowak RJ, Monson NL, Blackburn K, Hibbs RE, Vernino S, Noviello CM. J Neuroimmunol. 2024 Nov 15; 2024 Sep 8. PMID: 39277987.
- United States clinical practice experience with eculizumab in myasthenia gravis: symptoms, function, and immunosuppressant therapy use.Habib AA, Klink AJ, Muppidi S, Parthan A, Sader SC, Balanean A, Gajra A, Nowak RJ, Howard JF Jr. J Neurol. 2024 Sep; 2024 Jul 25. PMID: 39052039.
- Unveiling the proteome-wide autoreactome enables enhanced evaluation of emerging CAR T cell therapies in autoimmunity.Bodansky A, Yu DJ, Rallistan A, Kalaycioglu M, Boonyaratanakornkit J, Green DJ, Gauthier J, Turtle CJ, Zorn K, O'Donovan B, Mandel-Brehm C, Asaki J, Kortbawi H, Kung AF, Rackaityte E, Wang CY, Saxena A, de Dios K, Masi G, Nowak RJ, O'Connor KC, Li H, Diaz VE, Saloner R, Casaletto KB, Gontrum EQ, Chan B, Kramer JH, Wilson MR, Utz PJ, Hill JA, Jackson SW, Anderson MS, DeRisi JL. J Clin Invest. 2024 May 16; 2024 May 16. PMID: 38753445.
- Long-term safety and efficacy of zilucoplan in patients with generalized myasthenia gravis: interim analysis of the RAISE-XT open-label extension study.Howard JF Jr, Bresch S, Farmakidis C, Freimer M, Genge A, Hewamadduma C, Hinton J, Hussain Y, Juntas-Morales R, Kaminski HJ, Maniaol A, Mantegazza R, Masuda M, Nowak RJ, Sivakumar K, Śmiłowski M, Utsugisawa K, Vu T, Weiss MD, Zajda M, Bloemers J, Boroojerdi B, Brock M, de la Borderie G, Duda PW, Vanderkelen M, Leite MI. Ther Adv Neurol Disord. 2024; 2024 Apr 17. PMID: 38638673.
- A Noncanonical CD56dimCD16dim/- NK Cell Subset Indicative of Prior Cytotoxic Activity Is Elevated in Patients with Autoantibody-Mediated Neurologic Diseases.Yandamuri SS, Filipek B, Lele N, Cohen I, Bennett JL, Nowak RJ, Sotirchos ES, Longbrake EE, Mace EM, O'Connor KC. J Immunol. 2024 Mar 1. PMID: 38251887.
- Safety and Efficacy of Nipocalimab in Patients With Generalized Myasthenia Gravis: Results From the Randomized Phase 2 Vivacity-MG Study.Antozzi C, Guptill J, Bril V, Gamez J, Meuth SG, Nowak RJ, Quan D, Sevilla T, Jouvin MH, Jin J, Karcher K, Ramchandren S, Sun H, Ling L, Zhu Y, Arroyo S. Neurology. 2024 Jan 23; 2023 Dec 21. PMID: 38165333.
- Batoclimab as induction and maintenance therapy in patients with myasthenia gravis: rationale and study design of a phase 3 clinical trial.Benatar M, Wiendl H, Nowak R, Zheng Y, Macias W. BMJ Neurol Open. 2024; 2024 Jan 10. PMID: 38268752.
- Subcutaneous batoclimab in generalized myasthenia gravis: Results from a Phase 2a trial with an open-label extension.Nowak RJ, Breiner A, Bril V, Allen JA, Khan S, Levine T, Jacobs DH, Sahagian G, Siddiqi ZA, Xu J, Macias WL, Benatar M. Ann Clin Transl Neurol. 2024 Jan; 2023 Dec 7. PMID: 38062618.
- Unveiling the autoreactome: Proteome-wide immunological fingerprints reveal the promise of plasma cell depleting therapy.Bodansky A, Yu DJ, Rallistan A, Kalaycioglu M, Boonyaratanakornkit J, Green DJ, Gauthier J, Turtle CJ, Zorn K, O'Donovan B, Mandel-Brehm C, Asaki J, Kortbawi H, Kung AF, Rackaityte E, Wang CY, Saxena A, de Dios K, Masi G, Nowak RJ, O'Connor KC, Li H, Diaz VE, Casaletto KB, Gontrum EQ, Chan B, Kramer JH, Wilson MR, Utz PJ, Hill JA, Jackson SW, Anderson MS, DeRisi JL. medRxiv. 2023 Dec 20; 2023 Dec 20. PMID: 38196603.
- Remission of severe myasthenia gravis after autologous stem cell transplantation.Schlatter MI, Yandamuri SS, O'Connor KC, Nowak RJ, Pham MC, Obaid AH, Redman C, Provost M, McSweeney PA, Pearlman ML, Tees MT, Bowen JD, Nash RA, Georges GE. Ann Clin Transl Neurol. 2023 Nov; 2023 Sep 19. PMID: 37726935.
- Addressing Outcome Measure Variability in Myasthenia Gravis Clinical Trials.Guptill JT, Benatar M, Granit V, Habib AA, Howard JF Jr, Barnett-Tapia C, Nowak RJ, Lee I, Ruzhansky K, Dimachkie MM, Cutter GR, Kaminski HJ. Neurology. 2023 Sep 5; 2023 Apr 19. PMID: 37076302.
- Leg MRI as a Complementary Diagnostic Tool in the Assessment of Foot Drop.Torabi T, Zubair AS, Nowak RJ, Tseng B, Haims A, Roy B. J Clin Neuromuscul Dis. 2023 Sep 1. PMID: 37611274.
- Plasmapheresis Versus Intravenous Immunoglobulin in Patients With Autoimmune Neuromuscular and Neuro-immunological Conditions.Zubair AS, Rethana M, Ma A, McAlpine LS, Abulaban A, Munro BS, Patwa HS, Nowak RJ, Roy B. J Clin Neuromuscul Dis. 2023 Sep 1. PMID: 37611265.
- Individual myasthenia gravis autoantibody clones can efficiently mediate multiple mechanisms of pathology.Pham MC, Masi G, Patzina R, Obaid AH, Oxendine SR, Oh S, Payne AS, Nowak RJ, O'Connor KC. Acta Neuropathol. 2023 Aug; 2023 Jun 21. PMID: 37344701.
- MOGAD patient autoantibodies induce complement, phagocytosis, and cellular cytotoxicity.Yandamuri SS, Filipek B, Obaid AH, Lele N, Thurman JM, Makhani N, Nowak RJ, Guo Y, Lucchinetti CF, Flanagan EP, Longbrake EE, O'Connor KC. JCI Insight. 2023 Jun 8; 2023 Jun 8. PMID: 37097758.
- The Plasma Cell Infiltrate Populating the Muscle Tissue of Patients with Inclusion Body Myositis Features Distinct B Cell Receptor Repertoire Properties.Jiang R, Roy B, Wu Q, Mohanty S, Nowak RJ, Shaw AC, Kleinstein SH, O'Connor KC. Immunohorizons. 2023 May 1. PMID: 37171806.
- Clinicoserological insights into patients with immune checkpoint inhibitor-induced myasthenia gravis.Masi G, Pham MC, Karatz T, Oh S, Payne AS, Nowak RJ, Howard JF Jr, Guptill JT, Juel VC, O'Connor KC. Ann Clin Transl Neurol. 2023 May; 2023 Mar 16. PMID: 36924454.
- Randomized Double-Blind Placebo-Controlled Trial of the Corticosteroid-Sparing Effects of Immunoglobulin in Myasthenia Gravis.Bril V, Szczudlik A, Vaitkus A, Rozsa C, Kostera-Pruszczyk A, Hon P, Bednarik J, Tyblova M, Köhler W, Toomsoo T, Nowak RJ, Mozaffar T, Freimer ML, Nicolle MW, Magnus T, Pulley MT, Rivner M, Dimachkie MM, Distad BJ, Pascuzzi RM, Babiar D, Lin J, Querolt Coll M, Griffin R, Mondou E. Neurology. 2023 Feb 14; 2022 Oct 21. PMID: 36270895.
- Neurogenic orthostatic hypotension after treatment with sorafenib.Wegner Wippel C, Deshpande H, Patwa H, Peixoto AJ. BMJ Case Rep. 2022 Dec 22; 2022 Dec 22. PMID: 36549761.
- Reemergence of pathogenic, autoantibody-producing B cell clones in myasthenia gravis following B cell depletion therapy.Fichtner ML, Hoehn KB, Ford EE, Mane-Damas M, Oh S, Waters P, Payne AS, Smith ML, Watson CT, Losen M, Martinez-Martinez P, Nowak RJ, Kleinstein SH, O'Connor KC. Acta Neuropathol Commun. 2022 Oct 28; 2022 Oct 28. PMID: 36307868.
- Myasthenia Gravis in the Setting of Immune Checkpoint Inhibitor Therapy: Practical Considerations and Opinion-Based Approach to Acute Management.Zubair AS, Roy B, Baehring JM, Nowak RJ. Cureus. 2022 Oct; 2022 Oct 24. PMID: 36439604.
- A preliminary, prospective study of peripheral neuropathy and cognitive function in patients with breast cancer during taxane therapy.Ibrahim EY, Munshani S, Domenicano I, Rodwin R, Nowak RJ, Pusztai L, Lustberg M, Ehrlich BE. PLoS One. 2022; 2022 Oct 7. PMID: 36206298.
- Heterogeneity of Acetylcholine Receptor Autoantibody-Mediated Complement Activity in Patients With Myasthenia Gravis.Obaid AH, Zografou C, Vadysirisack DD, Munro-Sheldon B, Fichtner ML, Roy B, Philbrick WM, Bennett JL, Nowak RJ, O'Connor KC. Neurol Neuroimmunol Neuroinflamm. 2022 Jul; 2022 Apr 26. PMID: 35473886.
- The clinical need for clustered AChR cell-based assay testing of seronegative MG.Masi G, Li Y, Karatz T, Pham MC, Oxendine SR, Nowak RJ, Guptill JT, O'Connor KC. J Neuroimmunol. 2022 Jun 15; 2022 Mar 25. PMID: 35366559.
- Reliability of patient self-reports to clinician-assigned functional scores of inclusion body myositis.Roy B, Zubair A, Petschke K, O'Connor KC, Paltiel AD, Nowak RJ. J Neurol Sci. 2022 May 15; 2022 Mar 15. PMID: 35344793.
- Myasthenia gravis complement activity is independent of autoantibody titer and disease severity.Fichtner ML, Hoarty MD, Vadysirisack DD, Munro-Sheldon B, Nowak RJ, O'Connor KC. PLoS One. 2022; 2022 Mar 15. PMID: 35290370.
- Phase 2 Trial of Rituximab in Acetylcholine Receptor Antibody-Positive Generalized Myasthenia Gravis: The BeatMG Study.Nowak RJ, Coffey CS, Goldstein JM, Dimachkie MM, Benatar M, Kissel JT, Wolfe GI, Burns TM, Freimer ML, Nations S, Granit V, Smith AG, Richman DP, Ciafaloni E, Al-Lozi MT, Sams LA, Quan D, Ubogu E, Pearson B, Sharma A, Yankey JW, Uribe L, Shy M, Amato AA, Conwit R, O'Connor KC, Hafler DA, Cudkowicz ME, Barohn RJ. Neurology. 2022 Jan 25; 2022 Jan 25. PMID: 34857535.
- Eculizumab in refractory generalized myasthenia gravis previously treated with rituximab: subgroup analysis of REGAIN and its extension study.Siddiqi ZA, Nowak RJ, Mozaffar T, O'Brien F, Yountz M, Patti F. Muscle Nerve. 2021 Dec; 2021 Oct 14. PMID: 34590717.
- Elevated N-Linked Glycosylation of IgG V Regions in Myasthenia Gravis Disease Subtypes.Mandel-Brehm C, Fichtner ML, Jiang R, Winton VJ, Vazquez SE, Pham MC, Hoehn KB, Kelleher NL, Nowak RJ, Kleinstein SH, Wilson MR, DeRisi JL, O'Connor KC. J Immunol. 2021 Oct 15; 2021 Sep 20. PMID: 34544801.
- Infection rate, mortality and characteristics of veterans with amyotrophic lateral sclerosis with COVID-19.Galea MD, Galea VP, Eberhart AC, Patwa HS, Howard I, Fournier CN, Bedlack RS. Muscle Nerve. 2021 Oct; 2021 Jul 30. PMID: 34255865.
- Telemedicine visits in myasthenia gravis: Expert guidance and the Myasthenia Gravis Core Exam (MG-CE).Guidon AC, Muppidi S, Nowak RJ, Guptill JT, Hehir MK, Ruzhansky K, Burton LB, Post D, Cutter G, Conwit R, Mejia NI, Kaminski HJ, Howard JF Jr. Muscle Nerve. 2021 Sep; 2021 Jul 7. PMID: 33959997.
- Influenza vaccination in autoimmune neuromuscular diseases: A survey of current practices and perceptions.Roy B, Litchman T, Torabi T, Nowak RJ. Muscle Nerve. 2021 Jun; 2021 Mar 23. PMID: 33711167.
- Electronic health record derived-impact of COVID-19 on myasthenia gravis.Roy B, Kovvuru S, Nalleballe K, Onteddu SR, Nowak RJ. J Neurol Sci. 2021 Apr 15; 2021 Feb 20. PMID: 33639420.
- Neurotoxicities associated with immune checkpoint inhibitor therapy.Duong SL, Barbiero FJ, Nowak RJ, Baehring JM. J Neurooncol. 2021 Apr; 2021 Jan 17. PMID: 33454891.
- Funding the Educational Mission in Neurology.Greer DM, Moeller J, Torres DR, Soni M, Cruz S, Tornes L, Patwa H, Gutmann L, Sacco R, Galetta S. Neurology. 2021 Mar 23; 2021 Feb 8. PMID: 33558302.
- Immunosuppression in chronic autoimmune neurological disorders during the COVID-19 pandemic.Kovvuru S, Nalleballe K, Onteddu SR, Sharma R, Jasti M, Kapoor N, Veerapaneni K, Yadala S, Dandu V, Archer R, Nowak RJ, Roy B. J Neurol Sci. 2021 Jan 15; 2020 Nov 27. PMID: 33256952.
- Utility of intrathecal baclofen pump in primary lateral sclerosis.Zubair AS, Raymond M, Patwa HS. J Neurol Sci. 2021 Jan 15; 2020 Nov 15. PMID: 33239209.
- Affinity maturation is required for pathogenic monovalent IgG4 autoantibody development in myasthenia gravis.Fichtner ML, Vieni C, Redler RL, Kolich L, Jiang R, Takata K, Stathopoulos P, Suarez PA, Nowak RJ, Burden SJ, Ekiert DC, O'Connor KC. J Exp Med. 2020 Dec 7. PMID: 32820331.
- COVID-19-associated risks and effects in myasthenia gravis (CARE-MG).Muppidi S, Guptill JT, Jacob S, Li Y, Farrugia ME, Guidon AC, Tavee JO, Kaminski H, Howard JF Jr, Cutter G, Wiendl H, Maas MB, Illa I, Mantegazza R, Murai H, Utsugisawa K, Nowak RJ. Lancet Neurol. 2020 Dec. PMID: 33212055.
- Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis.Jiang R, Hoehn KB, Lee CS, Pham MC, Homer RJ, Detterbeck FC, Aban I, Jacobson L, Vincent A, Nowak RJ, Kaminski HJ, Kleinstein SH, O'Connor KC. Proc Natl Acad Sci U S A. 2020 Dec 1; 2020 Nov 16. PMID: 33199596.
- Concomitant Immunosuppressive Therapy Use in Eculizumab-Treated Adults With Generalized Myasthenia Gravis During the REGAIN Open-Label Extension Study.Nowak RJ, Muppidi S, Beydoun SR, O'Brien FL, Yountz M, Howard JF Jr. Front Neurol. 2020; 2020 Nov 24. PMID: 33329303.
- Multiple Cranial Neuropathies as the Presenting Sign in a Patient with Metastatic BRAF-Mutated Lung Adenocarcinoma with Leptomeningeal Involvement.Fitzgerald BG, Grant M, Kone G, Patwa H, Rose M. Case Rep Oncol. 2020 Sep-Dec; 2020 Oct 15. PMID: 33250740.
- Eculizumab in Acute Motor Axonal Neuropathy: An Ethical Application of an Off-Label Indication.Roy B, Nowak RJ. J Clin Neuromuscul Dis. 2020 Sep. PMID: 32833730.
- Clinical features of LRP4/agrin-antibody-positive myasthenia gravis: A multicenter study.Rivner MH, Quarles BM, Pan JX, Yu Z, Howard JF Jr, Corse A, Dimachkie MM, Jackson C, Vu T, Small G, Lisak RP, Belsh J, Lee I, Nowak RJ, Baute V, Scelsa S, Fernandes JA, Simmons Z, Swenson A, Barohn R, Sanka RB, Gooch C, Ubogu E, Caress J, Pasnoor M, Xu H, Mei L. Muscle Nerve. 2020 Sep; 2020 Jun 10. PMID: 32483837.
- Single-cell repertoire tracing identifies rituximab-resistant B cells during myasthenia gravis relapses.Jiang R, Fichtner ML, Hoehn KB, Pham MC, Stathopoulos P, Nowak RJ, Kleinstein SH, O'Connor KC. JCI Insight. 2020 Jul 23; 2020 Jul 23. PMID: 32573488.
- Teleneurology during the COVID-19 pandemic: A step forward in modernizing medical care.Roy B, Nowak RJ, Roda R, Khokhar B, Patwa HS, Lloyd T, Rutkove SB. J Neurol Sci. 2020 Jul 15; 2020 May 21. PMID: 32460041.
- Exploring outcomes and characteristics of myasthenia gravis: Rationale, aims and design of registry - The EXPLORE-MG registry.Anil R, Kumar A, Alaparthi S, Sharma A, Nye JL, Roy B, O'Connor KC, Nowak RJ. J Neurol Sci. 2020 Jul 15; 2020 Apr 16. PMID: 32388060.
- Autoimmune Pathology in Myasthenia Gravis Disease Subtypes Is Governed by Divergent Mechanisms of Immunopathology.Fichtner ML, Jiang R, Bourke A, Nowak RJ, O'Connor KC. Front Immunol. 2020; 2020 May 27. PMID: 32547535.
- Guidance for the management of myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) during the COVID-19 pandemic.Jacob S, Muppidi S, Guidon A, Guptill J, Hehir M, Howard JF Jr, Illa I, Mantegazza R, Murai H, Utsugisawa K, Vissing J, Wiendl H, Nowak RJ. J Neurol Sci. 2020 May 15; 2020 Mar 25. PMID: 32247193.
- Response to eculizumab in patients with myasthenia gravis recently treated with chronic IVIg: a subgroup analysis of REGAIN and its open-label extension study.Jacob S, Murai H, Utsugisawa K, Nowak RJ, Wiendl H, Fujita KP, O'Brien F, Howard JF Jr. Ther Adv Neurol Disord. 2020; 2020 May 6. PMID: 32426038.
- Clinical Effects of the Self-administered Subcutaneous Complement Inhibitor Zilucoplan in Patients With Moderate to Severe Generalized Myasthenia Gravis: Results of a Phase 2 Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Trial.Howard JF Jr, Nowak RJ, Wolfe GI, Freimer ML, Vu TH, Hinton JL, Benatar M, Duda PW, MacDougall JE, Farzaneh-Far R, Kaminski HJ, Barohn R, Dimachkie M, Pasnoor M, Farmakidis C, Liu T, Colgan S, Benatar MG, Bertorini T, Pillai R, Henegar R, Bromberg M, Gibson S, Janecki T, Freimer M, Elsheikh B, Matisak P, Genge A, Guidon A, David W, Habib AA, Mathew V, Mozaffar T, Hinton JL, Hewitt W, Barnett D, Sullivan P, Ho D, Howard JF Jr, Traub RE, Chopra M, Kaminski HJ, Aly R, Bayat E, Abu-Rub M, Khan S, Lange D, Holzberg S, Khatri B, Lindman E, Olapo T, Sershon LM, Lisak RP, Bernitsas E, Jia K, Malik R, Lewis-Collins TD, Nicolle M, Nowak RJ, Sharma A, Roy B, Nye J, Pulley M, Berger A, Shabbir Y, Sachdev A, Patterson K, Siddiqi Z, Sivak M, Bratton J, Small G, Kohli A, Fetter M, Vu T, Lam L, Harvey B, Wolfe GI, Silvestri N, Patrick K, Zakalik K, Duda PW, MacDougall J, Farzaneh-Far R, Pontius A, Hoarty M. JAMA Neurol. 2020 May 1. PMID: 32065623.
- Differential response to rituximab in anti-AChR and anti-MuSK positive myasthenia gravis patients: a single-center retrospective study.Litchman T, Roy B, Kumar A, Sharma A, Njike V, Nowak RJ. J Neurol Sci. 2020 Apr 15; 2020 Jan 18. PMID: 32028072.
- Amyotrophic Lateral Sclerosis Among Veterans Deployed in Support of Post-9/11 U.S. Conflicts.Sagiraju HKR, Živković S, VanCott AC, Patwa H, Gimeno Ruiz de Porras D, Amuan ME, Pugh MJV. Mil Med. 2020 Mar 2. PMID: 31642489.
- Electrical impedance myography as a biomarker of inclusion body myositis: A cross-sectional study.Roy B, Rutkove SB, Nowak RJ. Clin Neurophysiol. 2020 Feb; 2019 Dec 6. PMID: 31865137.
- Clinical Reasoning: Progressive proximal weakness in a 56-year-old man with bone pain.Torabi T, Huttner A, Nowak RJ, Roy B. Neurology. 2019 Nov 19. PMID: 31740511.
- Neuropathy with vascular endothelial growth factor receptor tyrosine kinase inhibitors: A meta-analysis.Roy B, Das A, Ashish K, Bandyopadhyay D, Maiti A, Chakraborty S, Stone ME, Philpotts LL, Nowak RJ, Patwa HS. Neurology. 2019 Jul 9; 2019 Jun 5. PMID: 31167931.
- Long-term safety and efficacy of eculizumab in generalized myasthenia gravis.Muppidi S, Utsugisawa K, Benatar M, Murai H, Barohn RJ, Illa I, Jacob S, Vissing J, Burns TM, Kissel JT, Nowak RJ, Andersen H, Casasnovas C, de Bleecker JL, Vu TH, Mantegazza R, O'Brien FL, Wang JJ, Fujita KP, Howard JF Jr. Muscle Nerve. 2019 Jul; 2019 Mar 8. PMID: 30767274.
- Characterization of pathogenic monoclonal autoantibodies derived from muscle-specific kinase myasthenia gravis patients.Takata K, Stathopoulos P, Cao M, Mané-Damas M, Fichtner ML, Benotti ES, Jacobson L, Waters P, Irani SR, Martinez-Martinez P, Beeson D, Losen M, Vincent A, Nowak RJ, O'Connor KC. JCI Insight. 2019 Jun 20; 2019 Jun 20. PMID: 31217355.
- Autoantibodies against Neurologic Antigens in Nonneurologic Autoimmunity.Stathopoulos P, Chastre A, Waters P, Irani S, Fichtner ML, Benotti ES, Guthridge JM, Seifert J, Nowak RJ, Buckner JH, Holers VM, James JA, Hafler DA, O'Connor KC. J Immunol. 2019 Apr 15; 2019 Mar 1. PMID: 30824481.
- Thymectomy may not be associated with clinical improvement in MuSK myasthenia gravis.Clifford KM, Hobson-Webb LD, Benatar M, Burns TM, Barnett C, Silvestri NJ, Howard JF Jr, Visser A, Crum BA, Nowak R, Beekman R, Kumar A, Ruzhansky K, Chen IA, Pulley MT, Laboy SM, Fellman MA, Howard DB, Kolb NA, Greene SM, Pasnoor M, Dimachkie MM, Barohn RJ, Hehir MK. Muscle Nerve. 2019 Apr; 2019 Jan 14. PMID: 30575980.
- Benefits and Risks of Therapeutic Cannabinoids for Neurologic Disorders.Patwa HS. Clin Ther. 2018 Sep; 2018 Sep 14. PMID: 30224192.
- Independent home use of a brain-computer interface by people with amyotrophic lateral sclerosis.Wolpaw JR, Bedlack RS, Reda DJ, Ringer RJ, Banks PG, Vaughan TM, Heckman SM, McCane LM, Carmack CS, Winden S, McFarland DJ, Sellers EW, Shi H, Paine T, Higgins DS, Lo AC, Patwa HS, Hill KJ, Huang GD, Ruff RL. Neurology. 2018 Jul 17; 2018 Jun 27. PMID: 29950436.
- B cells in the pathophysiology of myasthenia gravis.Yi JS, Guptill JT, Stathopoulos P, Nowak RJ, O'Connor KC. Muscle Nerve. 2018 Feb; 2017 Sep 30. PMID: 28940642.
- Mechanisms underlying B cell immune dysregulation and autoantibody production in MuSK myasthenia gravis.Stathopoulos P, Kumar A, Heiden JAV, Pascual-Goñi E, Nowak RJ, O'Connor KC. Ann N Y Acad Sci. 2018 Jan. PMID: 29381221.
- Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study.Howard JF Jr, Utsugisawa K, Benatar M, Murai H, Barohn RJ, Illa I, Jacob S, Vissing J, Burns TM, Kissel JT, Muppidi S, Nowak RJ, O'Brien F, Wang JJ, Mantegazza R. Lancet Neurol. 2017 Dec; 2017 Oct 20. PMID: 29066163.
- Rituximab as treatment for anti-MuSK myasthenia gravis: Multicenter blinded prospective review.Hehir MK, Hobson-Webb LD, Benatar M, Barnett C, Silvestri NJ, Howard JF Jr, Howard D, Visser A, Crum BA, Nowak R, Beekman R, Kumar A, Ruzhansky K, Chen IA, Pulley MT, LaBoy SM, Fellman MA, Greene SM, Pasnoor M, Burns TM. Neurology. 2017 Sep 5; 2017 Aug 11. PMID: 28801338.
- Immunoglobulin therapy in the treatment of multifocal motor neuropathy.Kumar A, Patwa HS, Nowak RJ. J Neurol Sci. 2017 Apr 15; 2017 Jan 25. PMID: 28320129.
- Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing.Vander Heiden JA, Stathopoulos P, Zhou JQ, Chen L, Gilbert TJ, Bolen CR, Barohn RJ, Dimachkie MM, Ciafaloni E, Broering TJ, Vigneault F, Nowak RJ, Kleinstein SH, O'Connor KC. J Immunol. 2017 Feb 15; 2017 Jan 13. PMID: 28087666.
- Durability of the Rituximab Response in Acetylcholine Receptor Autoantibody-Positive Myasthenia Gravis.Robeson KR, Kumar A, Keung B, DiCapua DB, Grodinsky E, Patwa HS, Stathopoulos PA, Goldstein JM, O'Connor KC, Nowak RJ. JAMA Neurol. 2017 Jan 1. PMID: 27893014.
- Can a Point-of-Care Troponin I Assay be as Good as a Central Laboratory Assay? A MIDAS Investigation.Peacock WF, Diercks D, Birkhahn R, Singer AJ, Hollander JE, Nowak R, Safdar B, Miller CD, Peberdy M, Counselman F, Chandra A, Kosowsky J, Neuenschwander J, Schrock J, Lee-Lewandrowski E, Arnold W, Nagurney J. Ann Lab Med. 2016 Sep. PMID: 27374704.
- Compromised fidelity of B-cell tolerance checkpoints in AChR and MuSK myasthenia gravis.Lee JY, Stathopoulos P, Gupta S, Bannock JM, Barohn RJ, Cotzomi E, Dimachkie MM, Jacobson L, Lee CS, Morbach H, Querol L, Shan JL, Vander Heiden JA, Waters P, Vincent A, Nowak RJ, O'Connor KC. Ann Clin Transl Neurol. 2016 Jun; 2016 Apr 27. PMID: 27547772.
- Exacerbation of myasthenia gravis in a patient with melanoma treated with pembrolizumab.Lau KH, Kumar A, Yang IH, Nowak RJ. Muscle Nerve. 2016 Jun; 2016 May 19. PMID: 27065302.
- Autoreactive T Cells from Patients with Myasthenia Gravis Are Characterized by Elevated IL-17, IFN-γ, and GM-CSF and Diminished IL-10 Production.Cao Y, Amezquita RA, Kleinstein SH, Stathopoulos P, Nowak RJ, O'Connor KC. J Immunol. 2016 Mar 1; 2016 Jan 29. PMID: 26826242.
- Previously undiagnosed fatal familial haemophagocytic lymphohistiocytosis in a 24-year-old woman.Barmettler S, Nowak RJ, Parker T, Price C. BMJ Case Rep. 2016 Feb 22; 2016 Feb 22. PMID: 26903364.
- Editorial by concerned physicians: Unintended effect of the orphan drug act on the potential cost of 3,4-diaminopyridine.Burns TM, Smith GA, Allen JA, Amato AA, Arnold WD, Barohn R, Benatar M, Bird SJ, Bromberg M, Chahin N, Ciafaloni E, Cohen JA, Corse A, Crum BA, David WS, Dimberg E, Sousa EA, Donofrio PD, Dyck PJ, Engel AG, Ensrud ER, Ferrante M, Freimer M, Gable KL, Gibson S, Gilchrist JM, Goldstein JM, Gooch CL, Goodman BP, Gorelov D, Gospe SM Jr, Goyal NA, Guidon AC, Guptill JT, Gutmann L, Gutmann L, Gwathmey K, Harati Y, Harper CM Jr, Hehir MK, Hobson-Webb LD, Howard JF Jr, Jackson CE, Johnson N, Jones SM, Juel VC, Kaminski HJ, Karam C, Kennelly KD, Khella S, Khoury J, Kincaid JC, Kissel JT, Kolb N, Lacomis D, Ladha S, Larriviere D, Lewis RA, Li Y, Litchy WJ, Logigian E, Lou JS, MacGowen DJ, Maselli R, Massey JM, Mauermann ML, Mathews KD, Meriggioli MN, Miller RG, Moon JS, Mozaffar T, Nations SP, Nowak RJ, Ostrow LW, Pascuzzi RM, Peltier A, Ruzhansky K, Richman DP, Ross MA, Rubin DI, Russell JA, Sachs GM, Salajegheh MK, Saperstein DS, Scelsa S, Selcen D, Shaibani A, Shieh PB, Silvestri NJ, Singleton JR, Smith BE, So YT, Solorzano G, Sorenson EJ, Srinivasen J, Tavee J, Tawil R, Thaisetthawatkul P, Thornton C, Trivedi J, Vernino S, Wang AK, Webb TA, Weiss MD, Windebank AJ, Wolfe GI. Muscle Nerve. 2016 Feb; 2015 Dec 21. PMID: 26662952.
- Current and future immunotherapy targets in autoimmune neurology.Hu MY, Stathopoulos P, O'connor KC, Pittock SJ, Nowak RJ. Handb Clin Neurol. 2016. PMID: 27112694.
- Relationship Between Cerebrospinal Fluid Protein Levels and Electrophysiologic Abnormalities in Guillain-Barré Syndrome.DiCapua DB, Lakraj AA, Nowak RJ, Robeson K, Goldstein J, Patwa H. J Clin Neuromuscul Dis. 2015 Dec. PMID: 26583489.
- Demographic and clinical features of inclusion body myositis in North America.Paltiel AD, Ingvarsson E, Lee DK, Leff RL, Nowak RJ, Petschke KD, Richards-Shubik S, Zhou A, Shubik M, O'Connor KC. Muscle Nerve. 2015 Oct; 2015 Feb 17. PMID: 25557419.
- Current and emerging therapies for multiple sclerosis.Patwa HS. Clin Ther. 2014 Dec 1; 2014 Nov 26. PMID: 25433769.
- Puerto Rican founder mutation G787A in the SGCG gene: a case report of 2 siblings with LGMD 2C.DiCapua D, Patwa H. J Clin Neuromuscul Dis. 2014 Mar. PMID: 24534832.
- Cardioembolic stroke: practical considerations for patient risk management and secondary prevention.Amin H, Nowak RJ, Schindler JL. Postgrad Med. 2014 Jan. PMID: 24393752.
- Long-term benefit of rituximab in MuSK autoantibody myasthenia gravis patients.Keung B, Robeson KR, DiCapua DB, Rosen JB, O'Connor KC, Goldstein JM, Nowak RJ. J Neurol Neurosurg Psychiatry. 2013 Dec; 2013 Jun 12. PMID: 23761915.
- Commentaries on the current treatment of selected neurologic diseases.Patwa HS. Clin Ther. 2013 Oct. PMID: 24139419.
- Clinical characteristics of refractory myasthenia gravis patients.Suh J, Goldstein JM, Nowak RJ. Yale J Biol Med. 2013 Jun; 2013 Jun 13. PMID: 23766745.
- Novel mutations in the CLCN1 gene of myotonia congenita: 2 case reports.Lakraj AA, Miller G, Vortmeyer AO, Khokhar B, Nowak RJ, DiCapua DB. Yale J Biol Med. 2013 Mar; 2013 Mar 12. PMID: 23483815.
- Veterans health administration information systems as a resource for rare disorders research: Creutzfeldt-Jakob disease as a paradigm.Barash JA, Desai RA, Patwa HS. Mil Med. 2012 Nov. PMID: 23198511.
- Acute central retinal artery occlusion treated with intravenous recombinant tissue plasminogen activator.Nowak RJ, Amin H, Robeson K, Schindler JL. J Stroke Cerebrovasc Dis. 2012 Nov; 2012 Feb 18. PMID: 22349707.
- Evidence-based guideline: IV immunoglobulin in the treatment of neuromuscular disorders: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology.Li HF, Gao X, Hong Y, Patwa HS, Chaudhry V, Rae-Grant AD, So YT, Alto P. Neurology. 2012 Sep 25. PMID: 23008223.
- Autoantibodies produced at the site of tissue damage provide evidence of humoral autoimmunity in inclusion body myositis.Ray A, Amato AA, Bradshaw EM, Felice KJ, DiCapua DB, Goldstein JM, Lundberg IE, Nowak RJ, Ploegh HL, Spooner E, Wu Q, Willis SN, O'Connor KC. PLoS One. 2012; 2012 Oct 5. PMID: 23071619.
- Response of patients with refractory myasthenia gravis to rituximab: a retrospective study.Nowak RJ, Dicapua DB, Zebardast N, Goldstein JM. Ther Adv Neurol Disord. 2011 Sep. PMID: 22010039.
- Risperidone-induced bulbar palsy-like syndrome.Sico JJ, Patwa H. Dysphagia. 2011 Sep; 2010 Oct 5. PMID: 20922432.
- Rituximab in the management of refractory myasthenia gravis.Zebardast N, Patwa HS, Novella SP, Goldstein JM. Muscle Nerve. 2010 Mar. PMID: 19852027.
- Is needle electromyography safe in patients on anticoagulation or antiplatelet therapy?Patwa HS. Nat Clin Pract Neurol. 2009 Feb. PMID: 19194386.
- Use of fiberoptic endoscopic evaluation of swallowing (FEES) in patients with amyotrophic lateral sclerosis.Leder SB, Novella S, Patwa H. Dysphagia. 2004 Summer. PMID: 15383947.
- The effect of prednisone on the progression from ocular to generalized myasthenia gravis.Monsul NT, Patwa HS, Knorr AM, Lesser RL, Goldstein JM. J Neurol Sci. 2004 Feb 15. PMID: 14706214.
- A new drug for an old condition?Pagan FL, Restrepo L, Balish M, Patwa HS, Houff S. Headache. 2002 Jul-Aug. PMID: 12482228.