2010
Neurotransmitter Systems in Bipolar Disorder
Nakic M, Krystal J, Bhagwagar Z. Neurotransmitter Systems in Bipolar Disorder. 2010, 210-227. DOI: 10.1002/9780470661277.ch16.Peer-Reviewed Original ResearchRole of monoaminesNeuroendocrine systemNeurotransmitter systemsBipolar disorderPathophysiologyAcetylcholineMonoamines
2004
Bipolar disorder: the neglected psychosis
Bhagwagar Z, Goodwin G. Bipolar disorder: the neglected psychosis. Psychiatry 2004, 3: 67-70. DOI: 10.1383/psyt.3.10.67.52406.Peer-Reviewed Original ResearchBipolar disorderMainstay of treatmentNon-pharmacological interventionsSerious chronic illnessTraditional mood stabilizersLong-term treatmentMonoaminergic neurotransmitter systemsYears of lifeAtypical antipsychoticsMood stabilizersLifetime riskChronic illnessNeurotransmitter systemsNovel anticonvulsantMedical disordersEarly interventionAccurate diagnosisIllnessDisordersCognitive-behavioral approachDiagnosisInterventionTreatmentAntipsychoticsValproate
2002
Tryptophan Depletion Alters the Decision-Making of Healthy Volunteers through Altered Processing of Reward Cues
Rogers R, Tunbridge E, Bhagwagar Z, Drevets W, Sahakian B, Carter C. Tryptophan Depletion Alters the Decision-Making of Healthy Volunteers through Altered Processing of Reward Cues. Neuropsychopharmacology 2002, 28: 153-162. PMID: 12496952, DOI: 10.1038/sj.npp.1300001.Peer-Reviewed Original ResearchConceptsAmino acid drinkReward cuesOrbitofrontal cortexNegative outcomesReduced discriminationAltered processingTryptophan depletionHuman choiceCuesMonoamine neurotransmitter systemsAltered discriminationNeurotransmitter systemsBiasesDiscriminationCortexGamblesProcessingPsychiatric illnessCognitionHealthy volunteersAnhedoniaMoodFunctioningPresent studyLittle evidence