2017
Incorporating patient-specific CT-based ophthalmic anatomy in modeling iodine-125 eye plaque brachytherapy dose distributions
Tien CJ, Astrahan MA, Kim JM, Materin M, Chen Z, Nath R, Liu W. Incorporating patient-specific CT-based ophthalmic anatomy in modeling iodine-125 eye plaque brachytherapy dose distributions. Brachytherapy 2017, 16: 1057-1064. PMID: 28778599, DOI: 10.1016/j.brachy.2017.06.014.Peer-Reviewed Original ResearchConceptsEye modelDisc distanceDose differenceTumor apexPrescription doseOcular parametersPlaque SimulatorOcular structuresSubstantial dose differencesTarget volumePlaque positionDosimetric parametersPatientsClinical planningDosimetric impactSignificant differencesBrachytherapy planningSeed strengthPlaquesBrachytherapy dose distributionsDose distributionPatient-specific modelsDifferencesTumorsRetina
2016
State of dose prescription and compliance to international standard (ICRU-83) in intensity modulated radiation therapy among academic institutions
Das IJ, Andersen A, Chen Z, Dimofte A, Glatstein E, Hoisak J, Huang L, Langer MP, Lee C, Pacella M, Popple RA, Rice R, Smilowitz J, Sponseller P, Zhu T. State of dose prescription and compliance to international standard (ICRU-83) in intensity modulated radiation therapy among academic institutions. Practical Radiation Oncology 2016, 7: e145-e155. PMID: 28274405, DOI: 10.1016/j.prro.2016.11.003.Peer-Reviewed Original ResearchConceptsDose-volume histogramsDose prescriptionRadiation therapyHomogeneity indexICRU-83Stereotactic body radiation therapyBody radiation therapyTreatment sitesInstitutional review board clearanceLung sitesClinical trialsPelvic sitesPrescribed doseInternational guidelinesTumor siteArc therapyPatient treatmentTarget volumeTherapyPatientsDoseLevels of dosePrescriptionP-valueDose delivery
2014
Motion management in gastrointestinal cancers
Abbas H, Chang B, Chen ZJ. Motion management in gastrointestinal cancers. Journal Of Gastrointestinal Oncology 2014, 5: 223-35. PMID: 24982771, PMCID: PMC4074952, DOI: 10.3978/j.issn.2078-6891.2014.028.Peer-Reviewed Original Research
2009
AAPM recommendations on dose prescription and reporting methods for permanent interstitial brachytherapy for prostate cancer: Report of Task Group 137
Nath R, Bice WS, Butler WM, Chen Z, Meigooni AS, Narayana V, Rivard MJ, Yu Y. AAPM recommendations on dose prescription and reporting methods for permanent interstitial brachytherapy for prostate cancer: Report of Task Group 137. Medical Physics 2009, 36: 5310-5322. PMID: 19994539, PMCID: PMC2776817, DOI: 10.1118/1.3246613.Peer-Reviewed Original ResearchConceptsBiological equivalent doseTumor volumeDose prescriptionStandard of careProstate cancer patientsPermanent interstitial brachytherapyAcute single dosesEffects of edemaCancer patientsSurgical traumaIntraoperative implantationSingle dosesClinical trialsProstate cancerRadiobiological modelsCurrent recommendationsInterstitial brachytherapyMore specific guidelinesRoutine patient treatmentsDifferent dose distributionsTreatment planPatient treatmentTarget volumeMost implantsDose distribution
2000
Dosimetric effects of needle divergence in prostate seed implant using and radioactive seeds
Nath S, Chen Z, Yue N, Trumpore S, Peschel R. Dosimetric effects of needle divergence in prostate seed implant using and radioactive seeds. Medical Physics 2000, 27: 1058-1066. PMID: 10841410, DOI: 10.1118/1.598971.Peer-Reviewed Original ResearchConceptsMinimum target doseIodine-125 implantsTarget doseDose coverageTumor biological effective doseTarget dose coverageBiological effective doseBase of prostateRadioactive seedsProstate seed implantsProstate seedPalladium-103Target volumeEffective doseDosimetric qualityDosePatient implantsDosimetric effectsSeed implantsProstateImplantsMagnitude of degradationActual implantationNeedle orientationActual configuration