2012
Ocular aldehyde dehydrogenases: Protection against ultraviolet damage and maintenance of transparency for vision
Chen Y, Thompson DC, Koppaka V, Jester JV, Vasiliou V. Ocular aldehyde dehydrogenases: Protection against ultraviolet damage and maintenance of transparency for vision. Progress In Retinal And Eye Research 2012, 33: 28-39. PMID: 23098688, PMCID: PMC3570594, DOI: 10.1016/j.preteyeres.2012.10.001.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAldehyde dehydrogenasePutative regulatory functionTaxon-specific mannerNon-catalytic functionsRetinoic acid signalingALDH proteinsMaintenance of transparencyCellular transparencyAcid signalingCorneal crystallinsExogenous aldehydesEye developmentOxygen-induced damageCorneal cell proliferationStructural roleRegulatory functionsException of rabbitsMost mammalsRetinaldehyde dehydrogenasesLens crystallinsALDH1A1 proteinMammalian corneaAnimal speciesCell proliferationDependent oxidation
2009
Corneal aldehyde dehydrogenases: Multiple functions and novel nuclear localization
Stagos D, Chen Y, Cantore M, Jester JV, Vasiliou V. Corneal aldehyde dehydrogenases: Multiple functions and novel nuclear localization. Brain Research Bulletin 2009, 81: 211-218. PMID: 19720116, PMCID: PMC3025408, DOI: 10.1016/j.brainresbull.2009.08.017.Peer-Reviewed Original ResearchConceptsException of rabbitsCorneal epitheliumOcular tissuesMouse corneaProtective roleUVR exposureCorneaMessenger levelsNuclear presenceOxidative damageCorneal crystallinsSubstantial evidenceNovel nuclear localizationALDH3A1Rabbit keratocytesReactive aldehydesCell cycle regulationAntioxidant activityGene expressionALDHMost mammalsCycle regulationExogenous aldehydesNuclear localizationALDH1A1