Mass Spectrometry Analysis of Nucleic Acid Modifications: From Beginning to Future
Xie Y, Brás‐Costa C, Lin Z, Garcia B. Mass Spectrometry Analysis of Nucleic Acid Modifications: From Beginning to Future. Mass Spectrometry Reviews 2024 PMID: 39308031, DOI: 10.1002/mas.21907.Peer-Reviewed Original ResearchMass spectrometryRegulate gene expressionMS-based methodsNucleic acidsNucleic acid structuresGenomic methodsTranscriptome researchModification statusGenetic informationNucleic acid modificationsProtein translationNucleic acid sample preparationBiological functionsGene expressionMS analysisSample preparationAcid structuresBiological moleculesModified speciesHigh-throughputDiverse modificationsLiving organismsAccurate quantitative informationAcid modificationGenomeAbstract 2121: SUV39H1 Mediated Regulation Of KLF4 And KDM4a Coordinate Smooth Muscle Cell Phenotypic Plasticity
Chatterjee P, Chakraborty R, Sizer A, Xie Y, Hwa J, Martin K. Abstract 2121: SUV39H1 Mediated Regulation Of KLF4 And KDM4a Coordinate Smooth Muscle Cell Phenotypic Plasticity. Arteriosclerosis Thrombosis And Vascular Biology 2024, 44: a2121-a2121. DOI: 10.1161/atvb.44.suppl_1.2121.Peer-Reviewed Original ResearchRNA-seqPhenotypic plasticityEpigenetic regulationH3K9me3 repressive marksRNA-seq transcriptomicsContractile genesEpigenetic transcriptional repressionCell phenotypic plasticityH3K9me3 markExpression of SUV39H1Repressive marksTranscriptional repressionChromatin immunoprecipitationHistone methyltransferaseDedifferentiation in vitroIn vivoSUV39H1 knockdownH3K9me3MRNA stabilitySUV39H1Gene expressionPlasticity of vascular smooth muscle cellsRegulation of Klf4GenesH3K9me3 expression