2015
Combining glucose monitoring and insulin delivery into a single device: current progress and ongoing challenges of the artificial pancreas
Ang KH, Tamborlane WV, Weinzimer SA. Combining glucose monitoring and insulin delivery into a single device: current progress and ongoing challenges of the artificial pancreas. Expert Opinion On Drug Delivery 2015, 12: 1579-1582. PMID: 26389567, PMCID: PMC4837694, DOI: 10.1517/17425247.2015.1074174.Peer-Reviewed Original ResearchConceptsBurden of careGlucose monitoringInsulin deliveryMultiple hormone systemsOverall glucose levelsType 1 diabetesContinuous glucose monitoringGlycemic targetsSevere hypoglycemiaDiabetes controlInsulin delivery systemsInpatient settingGlucose levelsPharmacokinetic profileOutpatient environmentInsulin analoguesPump suspensionInsulin pumpHypoglycemiaPsychosocial tollHormone systemTarget rangeArtificial pancreasPreliminary findingsCare
2012
Accuracy and Precision of the Axis-Shield Afinion Hemoglobin A1c Measurement Device
Wood JR, Kaminski BM, Kollman C, Beck RW, Hall CA, Yun JP, Cengiz E, Haller MJ, Hassan K, Klingensmith GJ, Tamborlane WV. Accuracy and Precision of the Axis-Shield Afinion Hemoglobin A1c Measurement Device. Journal Of Diabetes Science And Technology 2012, 6: 380-386. PMID: 22538150, PMCID: PMC3380782, DOI: 10.1177/193229681200600224.Peer-Reviewed Original ResearchConceptsNational Glycohemoglobin Standardization ProgramPediatric practice settingsWhole blood samplesBlood samplesHigh-performance liquid chromatographyPractice settingsDCA deviceHigher A1C levelsBoronate affinity methodMeasurement of hemoglobinA1c levelsDiabetes mellitusClinic sitesA1C resultsClinical centersAfinionCapillary bloodPatient samplesCentral laboratoryConsortium sitesA1CImmunoassay methodStandardization ProgramHPLC methodAbsolute difference
2011
Health Utilities for Children and Adults With Type 1 Diabetes
Lee JM, Rhee K, O'Grady MJ, Basu A, Winn A, John P, Meltzer DO, Kollman C, Laffel LM, Lawrence JM, Tamborlane WV, Wysocki T, Xing D, Huang ES. Health Utilities for Children and Adults With Type 1 Diabetes. Medical Care 2011, 49: 924-931. PMID: 21544001, PMCID: PMC3210197, DOI: 10.1097/mlr.0b013e318216592c.Peer-Reviewed Original ResearchConceptsParent-proxy reportsType 1 diabetesHealth utilityProxy reportsEnd-stage renal diseaseEnd-stage complicationsStage renal diseaseChild Self-ReportSelf-ReportSignificant differencesRenal diseaseAdult Self-ReportHigher overall QoLOverall QoLCurrent QoLOverall qualityHigher QoLQoLFunction of ageType 1DiabetesAdultsComplicationsMethods of assessmentChildren
2009
A Tale of Two Compartments: Interstitial Versus Blood Glucose Monitoring
Cengiz E, Tamborlane WV. A Tale of Two Compartments: Interstitial Versus Blood Glucose Monitoring. Diabetes Technology & Therapeutics 2009, 11: s-11-s-16. PMID: 19469670, PMCID: PMC2903977, DOI: 10.1089/dia.2009.0002.Peer-Reviewed Original Research
2007
The Accuracy of the FreeStyle Navigator Continuous Glucose Monitoring System in Children With Type 1 Diabetes
Wilson DM, Beck RW, Tamborlane WV, Dontchev MJ, Kollman C, Chase P, Fox LA, Ruedy KJ, Tsalikian E, Weinzimer SA. The Accuracy of the FreeStyle Navigator Continuous Glucose Monitoring System in Children With Type 1 Diabetes. Diabetes Care 2007, 30: 59-64. PMID: 17192334, PMCID: PMC1764630, DOI: 10.2337/dc06-1407.Peer-Reviewed Original ResearchRelative Inaccuracy of the A1cNow in Children With Type 1 Diabetes
Fox L, Dontchev M, Ruedy K, Beck R, Kollman C, Messer L, Coffey J, Wilson D, Doyle E, Tamborlane W, Steffes M. Relative Inaccuracy of the A1cNow in Children With Type 1 Diabetes. Diabetes Care 2007, 30: 135-137. PMID: 17192346, PMCID: PMC1978195, DOI: 10.2337/dc06-0972.Peer-Reviewed Original ResearchChildDiabetes Mellitus, Type 1Glycated HemoglobinHumansLeast-Squares AnalysisReproducibility of ResultsSensitivity and Specificity
2006
Continuous subcutaneous insulin infusion (CSII) in children with type 1 diabetes
Tamborlane WV, Sikes KA, Steffen AT, Weinzimer SA. Continuous subcutaneous insulin infusion (CSII) in children with type 1 diabetes. Diabetes Research And Clinical Practice 2006, 74: s112-s115. PMID: 17182301, DOI: 10.1016/s0168-8227(06)70011-0.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildDiabetes Mellitus, Type 1HumansInsulin Infusion SystemsReproducibility of ResultsSafetyTreatment OutcomeConceptsContinuous subcutaneous insulin infusionSubcutaneous insulin infusionType 1 diabetesInsulin infusionEfficacy of CSIIExcessive weight gainInsulin pump therapyNew insulin analoguesQuality of lifePediatric patientsSevere hypoglycemiaHemoglobin levelsPump therapyTreatment optionsClinical studiesInsulin analoguesWeight gainDiabetesInfusionChildrenRecent studiesSafetyHypoglycemiaPatientsTherapy
2005
Limitations of statistical measures of error in assessing the accuracy of continuous glucose sensors.
Kollman C, Wilson DM, Wysocki T, Tamborlane WV, Beck RW. Limitations of statistical measures of error in assessing the accuracy of continuous glucose sensors. Diabetes Technology & Therapeutics 2005, 7: 665-72; discussion 673-4. PMID: 16241865, PMCID: PMC1805466, DOI: 10.1089/dia.2005.7.665.Peer-Reviewed Original ResearchConceptsStatistical methodsStatistical measuresModified gridComputer simulationsObserved p-valuesContinuous error grid analysisGrid analysisIdentical accuracyNull hypothesisActual dataGridSimulationsAccuracyErrorSensor accuracySubject effectsCorrelation patternsProbabilityOperating characteristicsInconsistent notionsAccuracy of newer-generation home blood glucose meters in a Diabetes Research in Children Network (DirecNet) inpatient exercise study.
Weinzimer SA, Beck RW, Chase HP, Fox LA, Buckingham BA, Tamborlane WV, Kollman C, Coffey J, Xing D, Ruedy KJ. Accuracy of newer-generation home blood glucose meters in a Diabetes Research in Children Network (DirecNet) inpatient exercise study. Diabetes Technology & Therapeutics 2005, 7: 675-80; discussion 681-3. PMID: 16241867, PMCID: PMC1351386, DOI: 10.1089/dia.2005.7.675.Peer-Reviewed Original ResearchConceptsHome glucose metersStandardized exercise protocolVenous blood samplesEffects of exerciseType 1 diabetesGlucose metersExercise protocolNocturnal hypoglycemiaExercise studiesVenous bloodGlucose levelsBlood samplesDetection of hypoglycemiaBlood glucose metersClinical settingHome blood glucose metersDiabetes researchCentral laboratoryHexokinase enzymatic methodGlucose measurementsGlucose concentrationAccuracy of the modified Continuous Glucose Monitoring System (CGMS) sensor in an outpatient setting: results from a diabetes research in children network (DirecNet) study.
Tansey MJ, Beck RW, Buckingham BA, Mauras N, Fiallo-Scharer R, Xing D, Killman C, Tamborlane WV, Ruedy KJ. Accuracy of the modified Continuous Glucose Monitoring System (CGMS) sensor in an outpatient setting: results from a diabetes research in children network (DirecNet) study. Diabetes Technology & Therapeutics 2005, 7: 109-14. PMID: 15738708, PMCID: PMC2254760, DOI: 10.1089/dia.2005.7.109.Peer-Reviewed Original ResearchBlood GlucoseBlood Glucose Self-MonitoringChildDiabetes Mellitus, Type 1HumansMonitoring, AmbulatoryReproducibility of Results
2004
GlucoWatch G2 Biographer alarm reliability during hypoglycemia in children.
Tsalikian E, Kollman C, Mauras N, Weinzimer S, Buckingham B, Xing D, Beck R, Ruedy K, Tamborlane W, Fiallo-Scharer R. GlucoWatch G2 Biographer alarm reliability during hypoglycemia in children. Diabetes Technology & Therapeutics 2004, 6: 559-66. PMID: 15628809, PMCID: PMC2302787, DOI: 10.1089/dia.2004.6.559.Peer-Reviewed Original ResearchLack of accuracy of continuous glucose sensors in healthy, nondiabetic children: results of the Diabetes Research in Children Network (DirecNet) accuracy study
Mauras N, Beck RW, Ruedy KJ, Kollman C, Tamborlane WV, Chase HP, Buckingham BA, Tsalikian E, Weinzimer S, Booth AD, Xing D. Lack of accuracy of continuous glucose sensors in healthy, nondiabetic children: results of the Diabetes Research in Children Network (DirecNet) accuracy study. The Journal Of Pediatrics 2004, 144: 770-775. PMID: 15192625, PMCID: PMC2248702, DOI: 10.1016/j.jpeds.2004.03.042.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBlood GlucoseChildDiagnostic Techniques, EndocrineFemaleHumansHypoglycemiaMaleReproducibility of Results