2005
β-Cell Function Across the Spectrum of Glucose Tolerance in Obese Youth
Weiss R, Caprio S, Trombetta M, Taksali SE, Tamborlane WV, Bonadonna R. β-Cell Function Across the Spectrum of Glucose Tolerance in Obese Youth. Diabetes 2005, 54: 1735-1743. PMID: 15919795, DOI: 10.2337/diabetes.54.6.1735.Peer-Reviewed Original Research
2002
Prevalence of Impaired Glucose Tolerance among Children and Adolescents with Marked Obesity
Sinha R, Fisch G, Teague B, Tamborlane WV, Banyas B, Allen K, Savoye M, Rieger V, Taksali S, Barbetta G, Sherwin RS, Caprio S. Prevalence of Impaired Glucose Tolerance among Children and Adolescents with Marked Obesity. New England Journal Of Medicine 2002, 346: 802-810. PMID: 11893791, DOI: 10.1056/nejmoa012578.Peer-Reviewed Original ResearchConceptsImpaired glucose toleranceType 2 diabetesC-peptide levelsGlucose toleranceGlucose tolerance testBeta-cell functionInsulin resistanceObese childrenInsulin levelsObese adolescentsGlucose levelsTwo-hour oral glucose tolerance testImpaired oral glucose toleranceOvert type 2 diabetesOral glucose tolerance testHomeostatic model assessmentOral glucose toleranceBody mass indexLevels of proinsulinBeta-cell failureIngestion of glucoseRatio of proinsulinSevere obesityMarked obesityChildhood obesity