1988
The treatment of indolent lymphomas: watchful waiting v aggressive combined modality treatment.
Young R, Longo D, Glatstein E, Ihde D, Jaffe E, DeVita V. The treatment of indolent lymphomas: watchful waiting v aggressive combined modality treatment. Seminars In Hematology 1988, 25: 11-6. PMID: 2456618.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Combined Chemotherapy ProtocolsCombined Modality TherapyCyclophosphamideDoxorubicinEtoposideEvaluation Studies as TopicHumansLeucovorinLeukemiaLeukemia, Radiation-InducedLymph NodesLymphoma, Non-HodgkinMechlorethamineMethotrexateNeoplasms, Multiple PrimaryNeoplasms, Radiation-InducedPalliative CarePrednisoneProcarbazineRandom AllocationVincristineConceptsAdvanced indolent lymphomaLimited radiation therapyTotal nodal irradiationIndolent lymphomaRadiation therapyModality treatmentInitial treatmentAggressive combined modality therapyCombined modality therapyEvaluable patientsInduction therapyInitial therapyNodal irradiationFirst remissionInitial remissionFrequent relapsesMedian durationModality therapySystemic therapyCombination chemotherapyMedian timeHistologic progressionLonger survivalPatient's diseasePatients
1979
Multimodal primary cancer treatment (adjuvant chemotherapy): current results and future prospects.
Weiss R, DeVita V. Multimodal primary cancer treatment (adjuvant chemotherapy): current results and future prospects. Annals Of Internal Medicine 1979, 91: 251-60. PMID: 380437, DOI: 10.7326/0003-4819-91-2-251.Peer-Reviewed Original ResearchConceptsDisease-free survivalPrimary treatment programGroup of patientsAdvanced diseaseTherapy regimensPrimary lesionSurgical removalAdult malignanciesPalliative treatmentTreatment resultsClinical trialsHuman trialsCancer mortalityChemotherapyMalignancyTreatment programsTreatmentRegimensPatientsLesionsCancer
1978
High volume intraperitoneal chemotherapy (“Belly bath”) for ovarian cancer
Jones R, Myers C, Guarino A, Dedrick R, Hubbard S, DeVita V. High volume intraperitoneal chemotherapy (“Belly bath”) for ovarian cancer. Cancer Chemotherapy And Pharmacology 1978, 1: 161-166. PMID: 373916, DOI: 10.1007/bf00253116.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntineoplastic AgentsClinical Trials as TopicEvaluation Studies as TopicFemaleHumansKineticsMethotrexateOvarian NeoplasmsPeritoneal DialysisRatsTime FactorsConceptsOvarian cancerIntraperitoneal chemotherapyPhase I clinical trialAdvanced stage diseaseIntraperitoneal fluid volumeIntraperitoneal methotrexateComplete remissionTreatment modalitiesPharmacologic principlesClinical trialsPeritoneal cavityTherapeutic effectivenessChemotherapyPharmacokinetic modelingDialysis fluidToxicologic studiesCancerFluid volumeDrug distributionRational chemotherapyFurther investigationRemissionPatientsMethotrexatePharmacokinetics
1977
Sequential staging in non-Hodgkin's lymphoma.
Chabner B, Johnson R, DeVita V, Canellos G, Hubbard S, Johnson S, Young R. Sequential staging in non-Hodgkin's lymphoma. Journal Of The National Cancer Institute 1977, 61: 993-7. PMID: 902262.Peer-Reviewed Original ResearchMeSH KeywordsBiopsyBone MarrowEvaluation Studies as TopicHumansLiverLymphographyLymphomaNeoplasm StagingConceptsNon-Hodgkin's lymphomaInvolvement of bone marrowBone marrow biopsyDiffuse lymphocytic lymphomaType of lymphomaPortal lymph nodesNon-surgical phaseCompletion of stagingNegative lymphangiogramLymphocytic lymphomaMarrow biopsyPositive lymphangiogramHistiocytic lymphomaAbdominal nodesLiver biopsyLymph nodesBone marrowLymphomaPhase of stagingNodular typeStage IIIStage IPatientsResults of stagingLaparotomy
1975
Single agent versus combination chemotherapy
DeVita V. Single agent versus combination chemotherapy. CA A Cancer Journal For Clinicians 1975, 25: 152-158. PMID: 165865, DOI: 10.3322/canjclin.25.3.152.Peer-Reviewed Original Research
1973
Initial clinical trials with methyl‐ccnu 1‐(2‐chloroethyl)‐3‐(4‐methyl cyclohexyl)‐1‐nitrosourea (meccnu)
Young R, Walker M, Canellos G, Schein P, Chabner B, Devita V. Initial clinical trials with methyl‐ccnu 1‐(2‐chloroethyl)‐3‐(4‐methyl cyclohexyl)‐1‐nitrosourea (meccnu). Cancer 1973, 31: 1164-1169. PMID: 4705154, DOI: 10.1002/1097-0142(197305)31:5<1164::aid-cncr2820310519>3.0.co;2-4.Peer-Reviewed Original ResearchMeSH KeywordsCyclohexanesEvaluation Studies as TopicHematopoietic SystemHumansLeukopeniaNeoplasmsNitrosourea CompoundsThrombocytopeniaConceptsPrior therapyMultiple dosesClinical trialsCumulative marrow toxicityObjective therapeutic responseHepatic side effectsSingle oral doseReticulum cell sarcomaInitial clinical trialsPrimary brain tumorsPreliminary clinical trialsMarrow suppressionHodgkin's diseaseOral doseCell sarcomaMarrow toxicityPrimary toxicityTherapeutic responseBrain tumorsSide effectsPatientsConsiderable toxicitySubsequent courseMeCCNUDosesIntensive chemotherapy for Hodgkin's disease: long-term complications.
DeVita V, Arseneau J, Sherins R, Canellos G, Young R. Intensive chemotherapy for Hodgkin's disease: long-term complications. National Cancer Institute Monograph 1973, 36: 447-54. PMID: 4744600.Peer-Reviewed Original ResearchAntineoplastic AgentsDrug Therapy, CombinationDrug-Related Side Effects and Adverse ReactionsEvaluation Studies as TopicFemaleFollicle Stimulating HormoneHodgkin DiseaseHumansImmunosuppression TherapyLuteinizing HormoneMaleMechlorethamineNeoplasmsPrednisoneProcarbazineTestosteroneTime FactorsVincristineCombined drug treatment of Hodgkin's disease: remission induction, remission duration, and survival; an appraisal.
DeVita V. Combined drug treatment of Hodgkin's disease: remission induction, remission duration, and survival; an appraisal. National Cancer Institute Monograph 1973, 36: 373-9. PMID: 4744596.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAntineoplastic AgentsBiopsyCarmustineChlorambucilCyclophosphamideDactinomycinDrug Therapy, CombinationEvaluation Studies as TopicFollow-Up StudiesHodgkin DiseaseHumansMechlorethamineMiddle AgedPrednisoneProcarbazineRemission, SpontaneousTime FactorsVinblastineVincristineCombination Chemotherapy and Survival in Advanced Hodgkin's Disease
Canellos G, Young R, Berard C, DeVita V. Combination Chemotherapy and Survival in Advanced Hodgkin's Disease. JAMA Internal Medicine 1973, 131: 388-390. PMID: 4569375, DOI: 10.1001/archinte.1973.00320090078008.Peer-Reviewed Original Research
1971
Peritoneoscopy in the staging of Hodgkin's disease.
DeVita V, Bagley C, Goodell B, O'Kieffe D, Trujillo N. Peritoneoscopy in the staging of Hodgkin's disease. Cancer Research 1971, 31: 1746-50. PMID: 4256359.Peer-Reviewed Original Research