2024
Improving care after stillbirth
Sweeney L, Reddy U, Xu X. Improving care after stillbirth. American Journal Of Obstetrics And Gynecology 2024 PMID: 39547349, DOI: 10.1016/j.ajog.2024.11.009.Peer-Reviewed Original ResearchThe relationship between perceived discrimination and reported nutrient intake among pregnant individuals of minoritized racial and ethnic groups
Johnson T, Kan A, Bonner L, Van Horn L, Kershaw K, Grobman W, Lindsay K, Debbink M, Mercer B, Haas D, Saade G, Reddy U, Parry S, Simhan H, Robinson D. The relationship between perceived discrimination and reported nutrient intake among pregnant individuals of minoritized racial and ethnic groups. Journal Of The Academy Of Nutrition And Dietetics 2024 PMID: 39542239, DOI: 10.1016/j.jand.2024.11.007.Peer-Reviewed Original ResearchTotal energy intakeFalse discovery rate correctionPerceived discriminationNutrient intakeEnergy intakeMonths prior to pregnancySaturated fatIntake of total fatRisk of adverse pregnancy outcomesBlock Food Frequency QuestionnaireNulliparous Pregnancy Outcomes StudyIntake of saturated fatMonitoring Mothers-to-BeIntake of dietary fiberFood frequency questionnaireSecondary data analysisAdverse pregnancy outcomesMothers-to-bePregnancy Outcomes StudyEthnic groupsMultivariate regression modelFood frequencyFrequency questionnairePreconception periodPregnancy outcomesThe association of higher offspring early‐childhood weight gain with prepregnancy metabolic and bariatric surgery
Hilaire M, Babcock A, White G, Masson C, Salem R, Reddy U, Gallagher D, LeDuc C, Thaker V. The association of higher offspring early‐childhood weight gain with prepregnancy metabolic and bariatric surgery. Obesity 2024, 32: 2012-2023. PMID: 39497631, DOI: 10.1002/oby.24166.Peer-Reviewed Original ResearchConceptsOffspring growth trajectoriesBariatric surgeryHypertensive disorders of pregnancyWorld Health Organization Child Growth StandardsRoux-en-Y gastric bypassWeight gainHigher BMI z-scoreEarly-life weight gainNon-MB groupDisorders of pregnancyGestational diabetes mellitusGestational weight gainLow birth weightBMI z-scoreChild Growth StandardsScore-matched controlsPrepregnancy BMIGestational outcomesHypertensive disordersSleeve gastrectomyGastric bypassBirth weightPrepregnancyDiabetes mellitusGrowth standardsAdherence to recommended prenatal visit schedules and risk for stillbirth, according to probable cause of death
Cersonsky T, Ayala N, Tucker N, Saade G, Dudley D, Pinar H, Silver R, Reddy U, Lewkowitz A. Adherence to recommended prenatal visit schedules and risk for stillbirth, according to probable cause of death. European Journal Of Obstetrics & Gynecology And Reproductive Biology 2024, 303: 159-164. PMID: 39488137, DOI: 10.1016/j.ejogrb.2024.10.037.Peer-Reviewed Original ResearchRisk of stillbirthCause of deathIncreased risk of stillbirthHypertensive disordersPrenatal visit scheduleStillbirth Collaborative Research NetworkHigher risk of stillbirthSuboptimal prenatal careHypertensive disorders of pregnancyAssociated with higher riskDisorders of pregnancyVisit adherenceVisitation guidelinesPrenatal careSecondary analysisNon-adherenceVisit scheduleStillbirthIncreased riskMultivariate regressionStudy objectiveVisit frequencyPregnancyAdherenceGuidelinesOxytocin regimen used for induction of labor and pregnancy outcomes
REDDY U, SANDOVAL G, TITA A, SILVER R, MALLETT G, Kim H, EL-SAYED Y, RICE M, WAPNER R, ROUSE D, SAADE G, THORP J, CHAUHAN S, COSTANTINE M, CHIEN E, CASEY B, SRINIVAS S, SWAMY G, SIMHAN H, MACONES G, GROBMAN W, Network E. Oxytocin regimen used for induction of labor and pregnancy outcomes. American Journal Of Obstetrics & Gynecology MFM 2024, 6: 101508. PMID: 39357802, DOI: 10.1016/j.ajogmf.2024.101508.Peer-Reviewed Original ResearchInduction of laborLow-risk nulliparous patientsOxytocin regimensAdjusted relative risksAdjusted odds ratiosCesarean deliveryComposite of perinatal deathConfidence intervalsNeonatal respiratory supportLow-dose regimensHigh-dose oxytocin regimenSevere neonatal complicationsOperative vaginal delivery rateFrequency of cesarean deliverySecondary analysisEstimate adjusted relative risksElective induction of laborPerinatal deathRoutine induction of labourEstimate adjusted odds ratiosVaginal delivery rateRespiratory supportNulliparous patientsMHD groupMultivariable Poisson regressionPatient and Community Centered Approaches to Sepsis Among Birthing People
Richardson B, Cepin A, Grilo S, Moss R, Moller M, Brown S, Goffman D, Friedman A, Reddy U, Hall K. Patient and Community Centered Approaches to Sepsis Among Birthing People. Seminars In Perinatology 2024, 48: 151974. PMID: 39341761, DOI: 10.1016/j.semperi.2024.151974.Peer-Reviewed Original ResearchMaternal health equityHealth equityAcademic-community research partnershipsSevere maternal morbidityCo-designed interventionsBirthing peopleMaternal deathsUnderserved communitiesMaternal morbidityMoms studyResearch partnershipsSepsis-related morbidityCommunity centered approachRisk periodResearch principalsResearch processCentered approachCommunityMorbidityPeoplePostpartumInterventionEquityPartnershipBirthThe association between perinatal depressive symptoms and child neurodevelopment
Miller E, Costantine M, Mele L, Varner M, Reddy U, Wapner R, Thorp J, Saade G, Tita A, Rouse D, Sibai B, Mercer B, Caritis S, Casey B, Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network B. The association between perinatal depressive symptoms and child neurodevelopment. American Journal Of Obstetrics & Gynecology MFM 2024, 6: 101488. PMID: 39293588, DOI: 10.1016/j.ajogmf.2024.101488.Peer-Reviewed Original ResearchSocial determinants of healthPerinatal depressive symptomsDeterminants of healthDepression screeningYears of ageDepressive symptomsSocial determinantsCES-DPositive postpartum depression screenAntenatal depression screeningPerinatal depression screeningPostpartum depression screeningCES-D <Child neurodevelopmentOne-year postpartumAdverse neurodevelopmental outcomesMulticenter randomized trialMultivariate logistic regressionBirthing peoplePerinatal depressionYear postpartumChild cognitive outcomesIQ score <Thyroxine therapyNeurodevelopmental outcomesBlood Pressure Control in Pregnant Patients with Chronic Hypertension and Diabetes: Should <130/80 be the Target?
Harper L, Kuo H, Boggess K, Dugoff L, Sibai B, Lawrence K, Hughes B, Bell J, Aagaard K, Edwards R, Gibson K, Haas D, Plante L, Metz T, Casey B, Esplin S, Longo S, Hoffman M, Saade G, Hoppe K, Foroutan J, Tuuli M, Owens M, Simhan H, Frey H, Rosen T, Palatnik A, August P, Reddy U, Kinzler W, Su E, Krishna I, Nguyen N, Norton M, Skupski D, El-Sayed Y, Galis Z, Ambalavanan N, Oparil S, Szychowski J, Tita A. Blood Pressure Control in Pregnant Patients with Chronic Hypertension and Diabetes: Should <130/80 be the Target? American Journal Of Obstetrics And Gynecology 2024 PMID: 39288828, DOI: 10.1016/j.ajog.2024.09.006.Peer-Reviewed Original ResearchTarget blood pressureNeonatal intensive care unitLow blood pressure groupBlood pressure groupPerinatal outcomesAverage blood pressureChronic hypertensionMm HgBlood pressureCesarean deliveryNeonatal deathDiastolic BPRisk of NICU admissionCompare perinatal outcomesEvaluate risk ratiosLt;130/80 mm HgPreterm birth <Adverse perinatal outcomesMultivariable log-binomial regression modelsGoal blood pressureAverage diastolic BPPrimary composite outcomeSystolic BP <Log-binomial regression modelsAntenatal blood pressureLarge-Scale Proteomics in Early Pregnancy and Hypertensive Disorders of Pregnancy
Greenland P, Segal M, McNeil R, Parker C, Pemberton V, Grobman W, Silver R, Simhan H, Saade G, Ganz P, Mehta P, Catov J, Merz C, Varagic J, Khan S, Parry S, Reddy U, Mercer B, Wapner R, Haas D. Large-Scale Proteomics in Early Pregnancy and Hypertensive Disorders of Pregnancy. JAMA Cardiology 2024, 9: 791-799. PMID: 38958943, PMCID: PMC11223045, DOI: 10.1001/jamacardio.2024.1621.Peer-Reviewed Original ResearchArea under the receiver operating characteristic curveCase-control studyHypertensive disordersEarly pregnancyClinical dataSmall-for-gestational-age infantsPrediction of hypertensive disordersSmall-for-gestational-ageHypertensive disorders of pregnancyPrediction of HDPDisorders of pregnancyNested case-control studyPlasma samplesMulticenter observational studyStored plasma samplesReceiver operating characteristic curveBody mass indexGestational hypertensionNon-Hispanic blacksPreterm birthFetal sexFirst-trimesterNon-Hispanic whitesPregnancy outcomesMaternal raceCannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function
Metz T, Allshouse A, McMillin G, Greene T, Chung J, Grobman W, Haas D, Mercer B, Parry S, Reddy U, Saade G, Simhan H, Silver R. Cannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function. Obstetric Anesthesia Digest 2024, 44: 139-140. DOI: 10.1097/01.aoa.0001026572.72882.bd.Peer-Reviewed Original ResearchExposure to cannabisCannabis usePlacental functionPregnancy outcomesPrevalence of cannabis usePoor fetal growthAdverse pregnancy outcomesInfluence pregnancy outcomePlacental dysfunctionCannabis exposureFetal growthPregnant individualsSelf-reported useTobacco useCannabisDrug usePregnancyOutcome relationsPotential legal consequencesOutcomesAssociationExposureUseDysfunctionPublished researchPregnancy Outcomes in Patients With Hepatitis C Virus Infection
Hughes B, Sandoval G, Saade G, Clifton R, Reddy U, Bartholomew A, Salazar A, Chien E, Tita A, Thorp J, Metz T, Wapner R, Sabharwal V, Simhan H, Swamy G, Heyborne K, Sibai B, Grobman W, El-Sayed Y, Casey B, Parry S, Macones G, Prasad M. Pregnancy Outcomes in Patients With Hepatitis C Virus Infection. Obstetrics And Gynecology 2024, 144: 501-506. PMID: 39173174, DOI: 10.1097/aog.0000000000005703.Peer-Reviewed Original ResearchSmall-for-gestational-ageHepatitis C virusHepatitis C virus infectionCase groupIncreased oddsPreterm birthNeonatal infectionGestational diabetesMaternal outcomesHCV infectionBirth weightSmall-for-gestational-age birth weightAdmission to neonatal intensive careControl groupIncreased odds of preterm birthPositive hepatitis C virusOdds of NICU admissionOutcomes associated with pregnancyMulticenter prospective cohort studyOdds of preterm birthMaternal HCV infectionMaternal medical comorbiditiesSGA birth weightAdverse maternal outcomesC virus infectionRadon exposure and gestational diabetes mellitus: the nuMoM2b study
Zhang Y, Angley M, Lu L, Smith B, Grobman W, Wylie B, Reddy U, Kahe K. Radon exposure and gestational diabetes mellitus: the nuMoM2b study. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.0948.Peer-Reviewed Original ResearchAntepartum yoga and pregnancy outcomes in nulliparous individuals: a retrospective cohort study
Kawakita T, Atwani R, Huang J, Greenland P, Merz C, Grobman W, Christman M, Silver R, Mcneil R, Reddy U, Chung J, Parry S, Saade G. Antepartum yoga and pregnancy outcomes in nulliparous individuals: a retrospective cohort study. American Journal Of Obstetrics & Gynecology MFM 2024, 6: 101465. PMID: 39142536, DOI: 10.1016/j.ajogmf.2024.101465.Peer-Reviewed Original ResearchMaternal implications of fetal anomalies: a population-based cross-sectional study
Atwani R, Aziz M, Saade G, Reddy U, Kawakita T. Maternal implications of fetal anomalies: a population-based cross-sectional study. American Journal Of Obstetrics & Gynecology MFM 2024, 6: 101440. PMID: 39089580, DOI: 10.1016/j.ajogmf.2024.101440.Peer-Reviewed Original ResearchCongenital diaphragmatic herniaCongenital heart diseasePresence of fetal anomaliesAdjusted relative risksFetal anomaliesCleft lipMaternal morbidityDiaphragmatic herniaAdjusted risk differencesChromosomal disordersMultiple anomaliesLimb anomaliesHeart diseaseMaternal intensive care unit admissionRisk of severe maternal morbidityAssociated with maternal morbidityCyanotic congenital heart diseaseMultiple fetal anomaliesRisk of SMMAdverse maternal health outcomesIntensive care unit admissionAdverse maternal outcomesPopulation-based cross-sectional studySevere maternal morbidityIncreased absolute riskProgression of Gestational Subclinical Hypothyroidism and Hypothyroxinemia to Overt Hypothyroidism After Pregnancy: Pooled Analysis of Data from Two Randomized Controlled Trials
Varner M, Mele L, Casey B, Peaceman A, Reddy U, Wapner R, Thorp J, Saade G, Tita A, Rouse D, Sibai B, Costantine M, Mercer B, Caritis S, Bethesda. Progression of Gestational Subclinical Hypothyroidism and Hypothyroxinemia to Overt Hypothyroidism After Pregnancy: Pooled Analysis of Data from Two Randomized Controlled Trials. Thyroid 2024, 34: 1171-1176. PMID: 39028022, PMCID: PMC11563732, DOI: 10.1089/thy.2023.0616.Peer-Reviewed Original ResearchSubclinical hypothyroidismOvert hypothyroidismAssociated with higher ratesTPO levelsThyroid peroxidaseYear 5Gestational subclinical hypothyroidismNormal free T4Multicenter treatment trialThyroid replacement therapyYear of deliveryThyrotropin (TSHThyroid peroxidase levelsYear 1Randomized controlled trialsWeeks gestationPlacebo groupTSH valuesMaternal serumReplacement therapyFree T4Higher ratesHypothyroxinemiaThyroid functionHypothyroidismDiet quality, community food access, and glycemic control among nulliparous individuals with diabetes
Venkatesh K, Yee L, Wu J, Joseph J, Garner J, McNeil R, Scifres C, Mercer B, Reddy U, Silver R, Saade G, Parry S, Simhan H, Post R, Walker D, Grobman W. Diet quality, community food access, and glycemic control among nulliparous individuals with diabetes. Primary Care Diabetes 2024, 18: 506-510. PMID: 38972826, DOI: 10.1016/j.pcd.2024.06.011.Peer-Reviewed Original ResearchPre-conceptional Magnesium Intake and Low Birth Weight: Findings From the nuMoM2b Study
Kahe K, Zhang Y, Angley M, Reddy U. Pre-conceptional Magnesium Intake and Low Birth Weight: Findings From the nuMoM2b Study. Current Developments In Nutrition 2024, 8: 103076. DOI: 10.1016/j.cdnut.2024.103076.Peer-Reviewed Original ResearchPreconceptional Calcium Intake and Hypertensive Disorders of Pregnancy
Lu L, Zhang Y, Angley M, Reddy U, Fly A, Kahe K. Preconceptional Calcium Intake and Hypertensive Disorders of Pregnancy. Current Developments In Nutrition 2024, 8: 103292. DOI: 10.1016/j.cdnut.2024.103292.Peer-Reviewed Original ResearchAssociation of Maternal Zinc Intake With Hypertensive Disorders of Pregnancy: The nuMoM2b Study
Lu L, Zhang Y, Angley M, Reddy U, Fly A, Kahe K. Association of Maternal Zinc Intake With Hypertensive Disorders of Pregnancy: The nuMoM2b Study. Current Developments In Nutrition 2024, 8: 103018. DOI: 10.1016/j.cdnut.2024.103018.Peer-Reviewed Original ResearchAssociation of neighborhood social determinants of health and hypertensive disorders of pregnancy
Bank T, Lynch C, Yee L, Johnson J, Wu J, McNeil R, Mercer B, Simhan H, Reddy U, Silver R, Parry S, Saade G, Chung J, Wapner R, Grobman W, Venkatesh K. Association of neighborhood social determinants of health and hypertensive disorders of pregnancy. AJOG Global Reports 2024, 4: 100372. PMID: 39114583, PMCID: PMC11304865, DOI: 10.1016/j.xagr.2024.100372.Peer-Reviewed Original Research