2024
Large-Scale Proteomics in Early Pregnancy and Hypertensive Disorders of Pregnancy
Greenland P, Segal M, McNeil R, Parker C, Pemberton V, Grobman W, Silver R, Simhan H, Saade G, Ganz P, Mehta P, Catov J, Merz C, Varagic J, Khan S, Parry S, Reddy U, Mercer B, Wapner R, Haas D. Large-Scale Proteomics in Early Pregnancy and Hypertensive Disorders of Pregnancy. JAMA Cardiology 2024, 9: 791-799. PMID: 38958943, PMCID: PMC11223045, DOI: 10.1001/jamacardio.2024.1621.Peer-Reviewed Original ResearchArea under the receiver operating characteristic curveCase-control studyHypertensive disordersEarly pregnancyClinical dataSmall-for-gestational-age infantsPrediction of hypertensive disordersSmall-for-gestational-ageHypertensive disorders of pregnancyPrediction of HDPDisorders of pregnancyNested case-control studyPlasma samplesMulticenter observational studyStored plasma samplesReceiver operating characteristic curveBody mass indexGestational hypertensionNon-Hispanic blacksPreterm birthFetal sexFirst-trimesterNon-Hispanic whitesPregnancy outcomesMaternal raceDiet quality, community food access, and glycemic control among nulliparous individuals with diabetes
Venkatesh K, Yee L, Wu J, Joseph J, Garner J, McNeil R, Scifres C, Mercer B, Reddy U, Silver R, Saade G, Parry S, Simhan H, Post R, Walker D, Grobman W. Diet quality, community food access, and glycemic control among nulliparous individuals with diabetes. Primary Care Diabetes 2024, 18: 506-510. PMID: 38972826, DOI: 10.1016/j.pcd.2024.06.011.Peer-Reviewed Original ResearchDesign, rationale and protocol for Glycemic Observation and Metabolic Outcomes in Mothers and Offspring (GO MOMs): an observational cohort study
Group T, Scholtens D, LeBlanc E, Vesco K, Amy D, Bays K, Massimino S, Robinson S, Schell K, Walters G, Hillier T, Oshiro C, Cordero S, Howick C, Kim L, Martinez Y, Pishchalenko O, Wastlova V, Zork N, Mourad M, Lonier J, Reddy U, Acevedo J, Castillo J, Gomez M, Peguero B, Facco F, Feghali M, Bocan H, Stramowski S, Powe C, Edlow A, Barth W, Nathan D, Azevedo R, Baez A, Iroajanma C, Larkin M, Maya J, Michalopolous C, Neamonitaki N, Thangthaeng N, Yee L, Lowe W, Grobman W, Szmuilowicz E, Aguirre A, Guevara E, Mallett G, Matos S, Tyagi S, Spadola A, Catalano P, Azimirad A, Werner E, Rouse D, Malloy M, Parra F, Sherr J, Merriam A, Bitterman S, Considine E, Leventhal J, Perley L, Rink L, Steffen A, Thompson B, Zgorski M, Steffes M, Arends V, Killeen A, Siddique J, Bustamante P, Cheung Y, Freeze C, Grott T, Kuang A, Tull M, Linder B. Design, rationale and protocol for Glycemic Observation and Metabolic Outcomes in Mothers and Offspring (GO MOMs): an observational cohort study. BMJ Open 2024, 14: e084216. PMID: 38851233, PMCID: PMC11163666, DOI: 10.1136/bmjopen-2024-084216.Peer-Reviewed Original ResearchConceptsLarge-for-gestational-age birth weightMetabolic outcomesLarge-for-gestational-ageDiagnosis of gestational diabetesOral glucose tolerance testAdverse pregnancy outcomesVanderbilt University Institutional Review BoardCourse of pregnancyObservational cohort studyGlucose tolerance testNational Institute of DiabetesDigestive and Kidney DiseasesGDM treatmentWeeks gestationDetect such abnormalitiesPerinatal outcomesGDM screeningInstitutional review boardGestational diabetesFirst-trimesterPregnancy outcomesEarly pregnancyGlucose abnormalitiesBirth weightPregnant adults
2022
Association of N-Terminal Pro–Brain Natriuretic Peptide Concentration in Early Pregnancy With Development of Hypertensive Disorders of Pregnancy and Future Hypertension
Hauspurg A, Marsh D, McNeil R, Bairey Merz C, Greenland P, Straub A, Rouse C, Grobman W, Pemberton V, Silver R, Chen Y, Mercer B, Levine L, Hameed A, Hoffman M, Simhan H, Catov J, Reddy U, Willinger M, Davis M, Laposky A, Iams J, Dalton W, Latimer C, Polito L, Louis J, Wapner R, Fuchs K, Torres C, Lynch S, Onativia A, DiVito M, Nhan-Chang C, Basner R, Haas D, Foroud T, Perkins E, Barnes S, Winters A, McCormick C, Schubert F, Caritis S, Bickus M, Speer P, Emery S, Daftary A, Facco F, Peaceman A, Zee P, Campbell P, Shepard J, Williams C, Wing D, Wadhwa P, Nageotte M, Chung J, Rumney P, Porto M, Pham V, Parry S, Ludmir J, Elovitz M, Peters M, Araujo B, Pien G, Esplin M, Vorwaller K, Postma J, Morby V, Williams M, Meadows L, Parker C, Koch M, McFadden D, Alexander B, Yetukuri V, Hunter S, Holder T, Franklin H, DeCain M, Griggs C, Redline S, Mobley D, Surovec S, Ulanski J, Saade G. Association of N-Terminal Pro–Brain Natriuretic Peptide Concentration in Early Pregnancy With Development of Hypertensive Disorders of Pregnancy and Future Hypertension. JAMA Cardiology 2022, 7: 268-276. PMID: 35044418, PMCID: PMC8771430, DOI: 10.1001/jamacardio.2021.5617.Peer-Reviewed Original ResearchConceptsHigher NT-proBNP concentrationsNT-proBNP concentrationsHypertensive disordersSubclinical cardiac dysfunctionEarly pregnancyYear post partumHypertension 2Lower riskPregnancy outcomesCohort studyCardiac dysfunctionNatriuretic peptideN-terminal pro-brain natriuretic peptide concentrationN-terminal pro-brain natriuretic peptideEarly pregnancy body mass indexProspective multicenter observational studyPro-brain natriuretic peptidePost partumNulliparous Pregnancy Outcomes StudyFirst-trimester blood samplesAdverse pregnancy outcomesMulticenter observational studyFuture cardiovascular diseaseNatriuretic peptide concentrationsCardiovascular disease risk