1991
The role of phosphoinositide turnover in mediating the biphasic effect of angiotensin II on renal tubular transport.
Wang T, Chan Y. The role of phosphoinositide turnover in mediating the biphasic effect of angiotensin II on renal tubular transport. Journal Of Pharmacology And Experimental Therapeutics 1991, 256: 309-17. PMID: 1846421.Peer-Reviewed Original ResearchMeSH Keywords1-(5-Isoquinolinesulfonyl)-2-MethylpiperazineAngiotensin IIAnimalsBicarbonatesBiological TransportCalcium Channel BlockersDose-Response Relationship, DrugGallic AcidIsoquinolinesKidney Tubules, ProximalMalePerfusionPhosphatidylinositolsPiperazinesProtein Kinase InhibitorsRatsRats, Inbred StrainsSignal TransductionSodiumTetradecanoylphorbol AcetateConceptsM ANG IIAng IIBiphasic effectAngiotensin IIM TMBDose-dependent biphasic effectSodium transportPhosphoinositide turnoverIntracellular calcium mobilizationRenal tubular transportOriginal perfusateRat PCTLuminal perfusionCalcium mobilizationTubular transportFluid reabsorptionRat kidneyStimulatory effectJHCO3Total CO2 changesVolume markerRinger's solutionPossible roleCritical rolePrevious studies
1990
Mechanism of angiotensin II action on proximal tubular transport.
Wang T, Chan Y. Mechanism of angiotensin II action on proximal tubular transport. Journal Of Pharmacology And Experimental Therapeutics 1990, 252: 689-95. PMID: 2313594.Peer-Reviewed Original ResearchMeSH KeywordsAmilorideAngiotensin IIAnimalsBiological TransportDose-Response Relationship, DrugKidney Tubules, ProximalMaleProtein Kinase CRatsRats, Inbred StrainsSodiumTetradecanoylphorbol AcetateConceptsAng II actionFluid reabsorptionAng IILuminal perfusionAng II interactsAction of angiotensinAng II antagonistAngiotensin II actionM ANG IIPhosphoinositide turnoverProximal tubular transportRat proximal tubuleNa-H exchange mechanismOriginal perfusateRat PCTAngiotensin IIII antagonistLow dosePCT transportTubular transportProximal tubulesBicarbonate absorptionM amilorideStimulatory effectTotal CO2 changes