2012
Etiology, assessment, and management of aromatase inhibitor-related musculoskeletal symptoms.
Park SH, Knobf MT, Sutton KM. Etiology, assessment, and management of aromatase inhibitor-related musculoskeletal symptoms. Clinical Journal Of Oncology Nursing 2012, 16: 260-6. PMID: 22641317, DOI: 10.1188/12.cjon.260-266.Peer-Reviewed Original ResearchConceptsAdjuvant endocrine therapyMusculoskeletal symptomsAromatase inhibitorsEndocrine therapyHormone-responsive breast cancerAvailable evidenceSevere musculoskeletal symptomsBest available evidenceAI therapyPostmenopausal womenSurvival benefitClinical trialsSymptom distressBreast cancerMusculoskeletal assessmentClinical decisionSymptomsTherapyEffective interventionsEffective management strategiesEtiologyWomenManagement strategiesPossible causesAssessment guidelines
2008
An Aerobic Weight-Loaded Pilot Exercise Intervention for Breast Cancer Survivors: Bone Remodeling and Body Composition Outcomes
Knobf MT, Insogna K, DiPietro L, Fennie K, Thompson AS. An Aerobic Weight-Loaded Pilot Exercise Intervention for Breast Cancer Survivors: Bone Remodeling and Body Composition Outcomes. Biological Research For Nursing 2008, 10: 34-43. PMID: 18705153, PMCID: PMC3540790, DOI: 10.1177/1099800408320579.Peer-Reviewed Original ResearchMeSH KeywordsAbsorptiometry, PhotonAnalysis of VarianceBody CompositionBody WeightBone ResorptionBreast NeoplasmsClinical Nursing ResearchCollagen Type IExerciseExercise TherapyFeasibility StudiesFemaleHumansMiddle AgedObesityOsteocalcinPerimenopausePilot ProjectsSurvivorsTime FactorsTreatment OutcomeWeight LiftingConceptsBreast cancer survivorsExercise interventionCancer survivorsBone remodelingBone lossFat massBody compositionTreadmill 3 times/weekDual-energy absorptiometry scansWeight gainNovel exercise interventionPilot exercise interventionYears of menopauseAdjuvant endocrine therapyBody composition outcomesOne-group pre-posttest designTimes/weekSerum NTxEndocrine therapySerum osteocalcinMean ageSerum biomarkersBone massHigh adherenceHigh risk
2006
The Influence of Endocrine Effects of Adjuvant Therapy on Quality of Life Outcomes in Younger Breast Cancer Survivors
Knobf MT. The Influence of Endocrine Effects of Adjuvant Therapy on Quality of Life Outcomes in Younger Breast Cancer Survivors. The Oncologist 2006, 11: 96-110. PMID: 16476831, DOI: 10.1634/theoncologist.11-2-96.Peer-Reviewed Original ResearchConceptsBreast cancer survivorsCancer survivorsLate effectsAdjuvant therapyGonadal toxicityPremature menopauseFertility concernsTreatment outcomesYoung breast cancer survivorsLife outcomesMenopausal symptom distressFertility preservation optionsAdverse treatment outcomesAgent-based chemotherapyYears of ageAdjuvant chemotherapyReversible amenorrheaEndocrine therapyIrregular mensesFollicular maturationPreservation optionsSymptom distressEndocrine effectsPsychosocial distressLower risk