Thejal Srikumar, MD, MPH
she/her/hers
Assistant ProfessorCards
About
Research
Publications
2025
Utility of computed tomography (CT) –based staging of mismatch repair deficient (dMMR) colon cancer.
Linhares S, Srikumar T, Shin C, Mathur M, Mongiu A, Leeds I, Pantel H, Cecchini M. Utility of computed tomography (CT) –based staging of mismatch repair deficient (dMMR) colon cancer. Journal Of Clinical Oncology 2025, 43: 45-45. DOI: 10.1200/jco.2025.43.4_suppl.45.Peer-Reviewed Original ResearchImmune checkpoint inhibitorsNeoadjuvant immune checkpoint inhibitorsPathological stageDMMR tumorsPMMR tumorsColon cancerSurgical resectionT stageRadiographic stagePathologic complete response rateUtilization of computed tomographyClinically staged patientsNode negative tumorsRate of understagingComplete response rateLocally advanced diseaseNode-positive diseaseClinical tumor stageNode-positive tumorsUpfront surgical resectionCorrelated to pathological stagingPrimary tumor growthLocalized colon cancerLow relapse rateEarly stage tumors
2024
Multimodality Treatment for Locally Advanced Gastric Adenocarcinoma
Srikumar T, Sundar R. Multimodality Treatment for Locally Advanced Gastric Adenocarcinoma. Surgical Clinics Of North America 2024, 105: 75-94. PMID: 39523078, DOI: 10.1016/j.suc.2024.06.007.Peer-Reviewed Educational MaterialsLongitudinal Curriculum to Address Wellness and Professional Development in a Hematology/Oncology Fellowship Program
Srikumar T, Stempel J, Goldberg S, Podoltsev N, Braun D, Lee A, Sanft T. Longitudinal Curriculum to Address Wellness and Professional Development in a Hematology/Oncology Fellowship Program. EMJ Oncology 2024, 1: 37-39. DOI: 10.33590/oncolamj/zgwb5064.Peer-Reviewed Original ResearchLongitudinal curriculum to address wellness and professional development in a hematology/oncology fellowship program.
Srikumar T, Stempel J, Goldberg S, Podoltsev N, Braun D, Lee A, Sanft T. Longitudinal curriculum to address wellness and professional development in a hematology/oncology fellowship program. Journal Of Clinical Oncology 2024, 42: 9004-9004. DOI: 10.1200/jco.2024.42.16_suppl.9004.Peer-Reviewed Original ResearchNeeds assessmentLongitudinal curriculumPatient Health Questionnaire 2Score of self-efficacyGeneral Self-Efficacy ScaleFellowship programsBaseline needs assessmentFaculty-led sessionsProfessional boundary settingSelf-Efficacy ScaleLevels of depressionProfessional developmentFirst-year fellowsDidactic sessionsPrevent burnoutChi-square testAcademic yearDebriefing sessionsQuestionnaire 2Baseline assessmentSelf-efficacyProfessional development skillsDepressed moodLeadership skillsBurnout
2020
Carpal Tunnel Syndrome/Ulnar Neuropathy
Srikumar T (2020). Carpal Tunnel Syndrome/Ulnar Neuropathy. In KA Gielissen, SF Hay, LM Whitman (Eds.), Yale Office-Based Medicine Curriculum, 7th edition. New Haven, CT: Yale University.Chapters
2019
Semiautomated Measure of Abdominal Adiposity Using Computed Tomography Scan Analysis
Srikumar T, Siegel E, Gu Y, Balagurunathan Y, Garcia A, Chen Y, Zhou J, Zhao X, Gillies R, Clark W, Gamenthaler A, Choi J, Shibata D. Semiautomated Measure of Abdominal Adiposity Using Computed Tomography Scan Analysis. Journal Of Surgical Research 2019, 237: 12-21. PMID: 30694786, PMCID: PMC7771581, DOI: 10.1016/j.jss.2018.11.027.Peer-Reviewed Original ResearchConceptsVisceral fat areaSubcutaneous fat areaTotal fat areaFat areaTomography scan analysisAbdominal adiposityIntraclass correlationL4-L5 intervertebral levelAverage body mass indexSubcutaneous fat ratioBody mass indexMedian ageRectal adenocarcinomaRisk stratificationMass indexIntervertebral levelObesity epidemicRadiologic methodsAdipose tissueSemiautomated measureAdiposityFat ratioHuman pathophysiologyImaging suiteSemiautomated method
2017
Quantitative Assessment of Visceral Obesity and Postoperative Colon Cancer Outcomes
Ozoya O, Siegel E, Srikumar T, Bloomer A, DeRenzis A, Shibata D. Quantitative Assessment of Visceral Obesity and Postoperative Colon Cancer Outcomes. Journal Of Gastrointestinal Surgery 2017, 21: 534-542. PMID: 28101721, PMCID: PMC5560865, DOI: 10.1007/s11605-017-3362-9.Peer-Reviewed Original ResearchConceptsBody mass indexVisceral obesityPostoperative morbidityObese patientsShort-term postoperative outcomesOverall complication rateColon cancer outcomesMeasures of adiposityColon cancer patientsMetabolic comorbiditiesPostoperative complicationsComplication ratePostoperative outcomesVisceral adipositySurgical morbidityMass indexRisk stratificationRetrospective studyCancer outcomesCancer patientsTomography assessmentPreoperative CTMortality rateStage IColon cancerAspergillus Terreus Brain Abscess Complicated by Tension Pneumocephalus in a Patient with Angiosarcoma
Srikumar T, Pabbathi S, Fernandez J, Nanjappa S. Aspergillus Terreus Brain Abscess Complicated by Tension Pneumocephalus in a Patient with Angiosarcoma. American Journal Of Case Reports 2017, 18: 33-37. PMID: 28070116, PMCID: PMC5240880, DOI: 10.12659/ajcr.900425.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnti-Bacterial AgentsAspergillosisAspergillusBacteremiaBrain AbscessCefepimeCephalosporinsDisease ProgressionDrug CombinationsDrug Therapy, CombinationGlucocorticoidsHemangiosarcomaHumansImmunocompromised HostMagnetic Resonance ImagingMalePneumocephalusProteus mirabilisSkin NeoplasmsStaphylococcus aureusSulfamethizoleTomography, X-Ray ComputedTreatment OutcomeTrimethoprimVancomycinVoriconazoleConceptsTension pneumocephalusComputed tomographyRight frontal lobe abscessCultures of lesionsFrontal lobe abscessLeft arm strengthLow-grade feverProteus mirabilis bacteremiaTrimethroprim/sulfamethoxazoleContinuous supplemental oxygenSystemic antifungal agentsSerial X-raysUpper extremity strengthIntravenous vancomycinRecurrent angiosarcomaBrain abscessesConservative managementEmergent evaluationPrompt diagnosisScalp angiosarcomaSupplemental oxygenIntracranial abscessPoor outcomeCase reportMental status
2016
Potential Use of Flavopiridol in Treatment of Chronic Diseases
Srikumar T, Padmanabhan J. Potential Use of Flavopiridol in Treatment of Chronic Diseases. Advances In Experimental Medicine And Biology 2016, 929: 209-228. PMID: 27771926, DOI: 10.1007/978-3-319-41342-6_9.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnti-Inflammatory AgentsAntineoplastic Agents, PhytogenicAntiviral AgentsApoptosisCardiovascular AgentsCell Cycle CheckpointsCell ProliferationChronic DiseaseDisease Models, AnimalDrug DiscoveryFlavonoidsHumansMolecular StructurePhytotherapyPiperidinesPlants, MedicinalSignal TransductionConceptsChronic diseasesElicit anti-inflammatory activityAberrant cell cycle activationNFκB-dependent signalingEffect of flavopiridolAnti-inflammatory activityArrests cell cycle progressionCell cycle activationInflammatory stimuliAnti-apoptotic genesAnti-proliferative activityCell cycle progressionDiseaseInhibits expressionCycle activationFlavopiridolCycle progressionCDK inhibitorsPotential useGrowth-arrested cellsRecent studiesRNA polymerase II activationTreatmentP-TEFb complexActivationIncreased incidence of FBXW7 and POLE proofreading domain mutations in young adult colorectal cancers
Kothari N, Teer J, Abbott A, Srikumar T, Zhang Y, Yoder S, Brohl A, Kim R, Reed D, Shibata D. Increased incidence of FBXW7 and POLE proofreading domain mutations in young adult colorectal cancers. Cancer 2016, 122: 2828-2835. PMID: 27244218, PMCID: PMC5014625, DOI: 10.1002/cncr.30082.Peer-Reviewed Original ResearchConceptsColorectal cancerYounger patientsExome sequencingOutcomes of patientsSporadic colorectal cancerUnique genetic alterationsFisher's exact testCRC data setsWhole-exome sequencingWorse survivalRetrospective studyTreatment modalitiesBRAF mutationsPatientsExact testFBXW7 geneLarger studyOlder agePatient samplesCohortFinal analysisSporadic cancersStatistical significanceGenetic alterationsFuture screening
Teaching & Mentoring
Clinical Care
Overview
Thejal Srikumar, MD, is a medical oncologist specializing in the care of young adults with gastrointestinal cancers and individuals at high risk for these cancers due to genetic mutations. She is dedicated to improving patient outcomes through a range of treatment approaches tailored to each individual's needs.
As an assistant professor of medicine at Yale School of Medicine, Dr. Srikumar is actively involved in research focusing on gastrointestinal malignancies and the impact of genetic factors on cancer risk. She is also the assistant program director of the Yale Medical Oncology-Hematology Fellowship Program.
Dr. Srikumar received her medical training from the University of South Florida Morsani College of Medicine and completed her residency and fellowship at Yale School of Medicine.
Clinical Specialties
Medical Oncology
Fact Sheets
Gastrointestinal Cancers
Learn More on Yale MedicineSmall Intestine Adenocarcinoma
Learn More on Yale MedicineRadiofrequency Ablation (RFA)
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Yale Medicine News
News
News
- December 31, 2024
Accolades, Awards & Honors
- August 29, 2024
Dr. Thejal Srikumar Joins Center for Gastrointestinal Cancers at Smilow Cancer Hospital and Yale Cancer Center
- August 14, 2024
Welcome New Staff, Faculty, Fellows, Postgrads & Postdocs (August 2024)
- June 07, 2024
Yale Cancer Center Researchers and Trainees Present at ASCO
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Fitkin Memorial Pavilion
Academic Office
789 Howard Avenue, Rm FMP 114
New Haven, CT 06519
Events
Jun 20253Tuesday
- EveryonePiyal Alam, DO - Thejal Srikumar, MD, MPH - Xavier Llor, MD, PhD