2023
Determinants of birthweight in rural Sri Lanka; a cohort study
Banda P, Amarasinghe G, Agampodi S. Determinants of birthweight in rural Sri Lanka; a cohort study. BMC Pediatrics 2023, 23: 40. PMID: 36690991, PMCID: PMC9869565, DOI: 10.1186/s12887-022-03830-0.Peer-Reviewed Original ResearchMeSH KeywordsBirth WeightCohort StudiesFemaleHumansInfant, NewbornPregnancyPremature BirthProspective StudiesSri LankaConceptsMother-infant cohortPregnant womenCohort studyPreterm birthPsychosocial wellbeingThird trimester pregnant womenPerinatal health issuesProspective cohort studySocioeconomic statusPrimary care levelMaternal care servicesAntenatal care programsHusband's education levelSelf-completed questionnaireMiddle-income settingsEducation levelHierarchical logistic regressionPregnancy registrationHypertensive disordersMaternal BMISingleton pregnanciesThird trimesterBaby's sexChronic diabetesPerinatal health
2022
Factors associated with early pregnancy anemia in rural Sri Lanka: Does being ‘under care’ iron out socioeconomic disparities?
Amarasinghe G, Agampodi T, Mendis V, Agampodi S. Factors associated with early pregnancy anemia in rural Sri Lanka: Does being ‘under care’ iron out socioeconomic disparities? PLOS ONE 2022, 17: e0274642. PMID: 36201463, PMCID: PMC9536542, DOI: 10.1371/journal.pone.0274642.Peer-Reviewed Original ResearchConceptsPregnancy anemiaPregnant womenFirst trimester pregnant womenSocioeconomic disparitiesRisk of anemiaOdds of anemiaFull blood countHistory of anemiaContinuum of carePeriod of gestationFamily Health ProgramHierarchical logistic regression modelsSelf-completed questionnaireLogistic regression modelsHealth care coveragePublic health infrastructureMaternal anemiaAntenatal careCohort studyBreast feedingContraceptive injectionMiddle-income countriesAnemia preventionRegression modelsAnemia controlAsthma in a prospective cohort of rural pregnant women from Sri Lanka: Need for better care during the pre-conceptional and antenatal period
Rajapakse S, Wickramasinghe N, Warnasekara J, Abeyrathna P, Amarasinghe G, Hettiarachchi AU, Jayasinghe IU, Koralegedara I, Agampodi TC, Agampodi SB. Asthma in a prospective cohort of rural pregnant women from Sri Lanka: Need for better care during the pre-conceptional and antenatal period. PLOS ONE 2022, 17: e0269888. PMID: 35834567, PMCID: PMC9282538, DOI: 10.1371/journal.pone.0269888.Peer-Reviewed Original ResearchMeSH KeywordsAsthmaCohort StudiesFemaleHumansPregnancyPregnancy OutcomePregnant WomenProspective StudiesSri LankaConceptsNew-onset wheezePregnant womenSecond trimesterAsthmatic womenPregnancy outcomesPregnant asthmatic womenEligible pregnant womenProspective cohort studyLow birth weightPrevalence of wheezeEffect of asthmaRural pregnant womenMaternal care programmeCohort studyProspective cohortHospital admissionAntenatal periodAsthma prevalenceFirst trimesterBirth weightClinical assessmentHigh prevalenceWheezeAsthmaTrimesterNon-alcoholic fatty liver disease (NAFLD): a significant predictor of gestational diabetes mellitus (GDM) and early pregnancy miscarriages—prospective study in Rajarata Pregnancy Cohort (RaPCo)
Koralegedara IS, Warnasekara JN, Dayaratne KG, De Silva FN, Premadasa JK, Agampodi SB. Non-alcoholic fatty liver disease (NAFLD): a significant predictor of gestational diabetes mellitus (GDM) and early pregnancy miscarriages—prospective study in Rajarata Pregnancy Cohort (RaPCo). BMJ Open Gastroenterology 2022, 9: e000831. PMID: 35193889, PMCID: PMC8867246, DOI: 10.1136/bmjgast-2021-000831.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseGestational diabetes mellitusEarly pregnancy miscarriageFatty liver diseasePregnancy miscarriageRisk factorsDiabetes mellitusLiver diseasePregnant womenRelative riskEffect of NAFLDImpact of NAFLDPopulation-based prospective cohort studyRepeat oral glucose tolerance testFirst trimester pregnant womenOral glucose tolerance testPregnancy care programsProspective cohort studyOnly independent predictorBody mass indexGlucose tolerance testWeeks of gestationSignificant risk factorsMajor risk factorHigh-risk mothersComparison of global definitions of metabolic syndrome in early pregnancy among the Rajarata Pregnancy Cohort participants in Sri Lanka
Jayasinghe IU, Agampodi TC, Dissanayake AK, Srimantha SM, Agampodi SB. Comparison of global definitions of metabolic syndrome in early pregnancy among the Rajarata Pregnancy Cohort participants in Sri Lanka. Scientific Reports 2022, 12: 2009. PMID: 35132136, PMCID: PMC8821546, DOI: 10.1038/s41598-022-05919-z.Peer-Reviewed Original ResearchConceptsPeriod of gestationTotal cholesterolEarly pregnancyMetabolic syndromeMetabolic derangementsCohort participantsPrevalence estimatesOral glucose tolerance testHigher MetS prevalenceNCEP ATP IIIAHA/NHLBIGlucose tolerance testDifferent diagnostic criteriaSignificant differencesCross-sectional analysisAge 27.9MetS prevalencePregnancy outcomesSerum lipidsMetS definitionsProspective studyPregnant womenPlasma glucoseTolerance testMetabolic parametersPrevalence and aetiologies of anaemia among first trimester pregnant women in Sri Lanka; the need for revisiting the current control strategies
Amarasinghe GS, Agampodi TC, Mendis V, Malawanage K, Kappagoda C, Agampodi SB. Prevalence and aetiologies of anaemia among first trimester pregnant women in Sri Lanka; the need for revisiting the current control strategies. BMC Pregnancy And Childbirth 2022, 22: 16. PMID: 34986796, PMCID: PMC8734253, DOI: 10.1186/s12884-021-04341-z.Peer-Reviewed Original ResearchConceptsFirst trimester pregnant womenFull blood countPregnant womenAnemic womenBlood countRobust public health infrastructureIron deficiencyPeripheral blood film examinationFull blood count analysisEtiology of anemiaMultiple micronutrient supplementationTrimester pregnant womenAnemic pregnant womenBlood count analysisBlood film examinationPublic health interventionsPositive predictive valueForms of malnutritionMaternal care programmeRed cell countRed cell indicesMiddle-income settingsPublic health infrastructureSerum B12B12 deficiency
2021
The hidden burden of adolescent pregnancies in rural Sri Lanka; findings of the Rajarata Pregnancy Cohort
Agampodi TC, Wickramasinghe ND, Jayakodi HG, Amarasinghe GS, Warnasekara JN, Hettiarachchi AU, Jayasinghe IU, Koralegedara IS, Gunarathne SP, Somasiri DK, Agampodi SB. The hidden burden of adolescent pregnancies in rural Sri Lanka; findings of the Rajarata Pregnancy Cohort. BMC Pregnancy And Childbirth 2021, 21: 494. PMID: 34233652, PMCID: PMC8265066, DOI: 10.1186/s12884-021-03977-1.Peer-Reviewed Original ResearchConceptsEdinburgh Postpartum Depression ScaleAdolescent pregnancyPregnancy cohortPregnant womenRural Sri LankaLower body mass indexUtilization of SexualLower hemoglobin levelsBody mass indexPostpartum Depression ScaleReproductive health servicesMental health statusPeriod of gestationHealth care servicesLow education levelMental health effectsResultsBaseline dataBlood investigationsPrimigravida mothersHemoglobin levelsMass indexFirst pregnancyClinical examinationMaternal healthSRH services
2020
The Rajarata Pregnancy Cohort (RaPCo): study protocol
Agampodi TC, Wickramasinghe ND, Prasanna RIR, Irangani MKL, Banda JMS, Jayathilake PMB, Hettiarachchi A, Amarasinghe G, Jayasinghe I, Koralagedara I, Gunarathne SP, Wickramage S, Warnasekara J, Lokunarangoda N, Mendis V, Dissanayaka AK, Premadasa J, Hettigama N, Koralagedara D, Weerasinghe M, Malawanage K, Jayakodi H, Wickramasinghe A, Agampodi SB. The Rajarata Pregnancy Cohort (RaPCo): study protocol. BMC Pregnancy And Childbirth 2020, 20: 374. PMID: 32586287, PMCID: PMC7318435, DOI: 10.1186/s12884-020-03056-x.Peer-Reviewed Original ResearchConceptsMaternal mental healthMaternal deathsMental healthSocial determinantsPregnancy cohortObstetric transitionEligible pregnant womenProspective cohort studyMaternal health outcomesMaternal mortality ratePreventable maternal deathsMaternal care programmeChild outcome dataAntenatal depressionCohort studyMiddle-income countriesFirst trimesterNeonatal periodPregnant womenClinical examinationMaternal healthEarly postpartumMaternal cohortStudy protocolMethodsThe study
2012
Inadequacy of the risk factor based approach to detect gestational diabetes mellitus
Dahanayaka N, Agampodi S, Ranasinghe O, Jayaweera P, Wickramasinghe W, Adhikari A, Chathurani H, Dissanayaka U. Inadequacy of the risk factor based approach to detect gestational diabetes mellitus. Ceylon Medical Journal 2012, 57: 5-9. PMID: 22453704, DOI: 10.4038/cmj.v57i1.4193.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusRisk factorsIADPSG criteriaPregnant womenDiabetes mellitusPrevalence of GDMOral glucose tolerance testCross-sectional descriptive studyEligible pregnant womenPregnancy Study GroupsGlucose tolerance testSectional descriptive studyPresent risk factorsGDM patientsGDM casesGestational ageWHO criteriaPlasma glucoseTolerance testStudy groupStudy populationDescriptive studyMedical officersHealth areaMellitusUtility of Quantitative Polymerase Chain Reaction in Leptospirosis Diagnosis: Association of Level of Leptospiremia and Clinical Manifestations in Sri Lanka
Agampodi SB, Matthias MA, Moreno AC, Vinetz JM. Utility of Quantitative Polymerase Chain Reaction in Leptospirosis Diagnosis: Association of Level of Leptospiremia and Clinical Manifestations in Sri Lanka. Clinical Infectious Diseases 2012, 54: 1249-1255. PMID: 22354922, PMCID: PMC3404689, DOI: 10.1093/cid/cis035.Peer-Reviewed Original ResearchConceptsQuantitative polymerase chain reactionClinical manifestationsPolymerase chain reactionBlood samplesChain reactionWhole bloodOnset of symptomsSensitivity of qPCRAssociation of levelsSerum/bloodMicroscopic agglutination test panelValid diagnostic testPatient blood samplesOptimal sample typeFailure patientsRenal failureWhole blood samplesPatient populationTimely diagnosisLeptospiral loadEndemic areasDay 2Day 15LeptospiremiaDiagnostic tests
2010
Incidence and effects of Varicella Zoster Virus infection on academic activities of medical undergraduates - a five-year follow-up study from Sri Lanka
Agampodi SB, Dharmaratne SD, Thevanesam V, Dassanayake S, Kumarihamy P, Ratnayake A. Incidence and effects of Varicella Zoster Virus infection on academic activities of medical undergraduates - a five-year follow-up study from Sri Lanka. BMC Infectious Diseases 2010, 10: 117. PMID: 20465846, PMCID: PMC2882915, DOI: 10.1186/1471-2334-10-117.Peer-Reviewed Original ResearchConceptsVaricella-zoster virus infectionZoster virus infectionVZV infectionPerson yearsVirus infectionFive-year followNumber of infectionsSelf-administered structured questionnaireVZV immunizationConclusionsThe incidenceCumulative incidenceRetrospective cohortIncidence densityMedical undergraduatesStudy cohortIncidence rateClinical appointmentsAdult populationInfectionSusceptible cohortCohortIncidenceUniversity of PeradeniyaSecond questionnaireSri Lankan medical undergraduates