2014
Characteristics of Rural Leptospirosis Patients Admitted to Referral Hospitals During the 2008 Leptospirosis Outbreak in Sri Lanka: Implications for Developing Public Health Control Measures
Agampodi SB, Nugegoda DB, Thevanesam V, Vinetz JM. Characteristics of Rural Leptospirosis Patients Admitted to Referral Hospitals During the 2008 Leptospirosis Outbreak in Sri Lanka: Implications for Developing Public Health Control Measures. American Journal Of Tropical Medicine And Hygiene 2014, 92: 139-144. PMID: 25331809, PMCID: PMC4347370, DOI: 10.4269/ajtmh.14-0465.Peer-Reviewed Original ResearchConceptsRisk factorsHospital-based case-control studyPublic health control measuresCase-control studyExposure risk factorsHealth control measuresFebrile patientsReferral hospitalCase patientsLeptospirosis patientsMean ageControl studyTropical settingsPatientsVicinity of homeLeptospirosis outbreaksDog ownershipIndividual exposureLeptospirosisMain predictorsDisease transmissionControl measuresMajor roleHospitalSettingHantavirus infection mimicking leptospirosis: how long are we going to rely on clinical suspicion?
Dahanayaka NJ, Agampodi SB, Bandaranayaka AK, Priyankara S, Vinetz JM. Hantavirus infection mimicking leptospirosis: how long are we going to rely on clinical suspicion? The Journal Of Infection In Developing Countries 2014, 8: 1072-5. PMID: 25116678, DOI: 10.3855/jidc.4115.Peer-Reviewed Original ResearchConceptsHantavirus infectionPopulation-based prospective studyDiagnostic facilitiesAcute hantavirus infectionClassical clinical pictureCases of leptospirosisClinical suspicionClinical pictureProspective studyEpidemiological featuresRetrospective analysisInfectious diseasesInfectionSerum samplesMedical staffLeptospirosisLeptospirosis outbreaksFeverDiseaseDiagnosisSuspicionSri LankaRegional Differences of Leptospirosis in Sri Lanka: Observations from a Flood-Associated Outbreak in 2011
Agampodi SB, Dahanayaka NJ, Bandaranayaka AK, Perera M, Priyankara S, Weerawansa P, Matthias MA, Vinetz JM. Regional Differences of Leptospirosis in Sri Lanka: Observations from a Flood-Associated Outbreak in 2011. PLOS Neglected Tropical Diseases 2014, 8: e2626. PMID: 24454971, PMCID: PMC3894175, DOI: 10.1371/journal.pntd.0002626.Peer-Reviewed Original ResearchConceptsOutbreak of leptospirosisClinical presentationAcute renal failureDifferent clinical presentationsCross-sectional studyMedian bacterial loadPublic health interventionsPublic health relevanceLeptospira interrogans serovar laiRenal failureSevere thrombocytopeniaInfectious disease epidemicsDifferent Leptospira speciesEtiological causesImportant causeHealth interventionsHealth relevanceLeptospirosisTropical diseasesBacterial loadLeptospira kirschneriLeptospirosis outbreaksSerovar laiLeptospira speciesL. kirschneri
2013
Outbreak of leptospirosis after white-water rafting: sign of a shift from rural to recreational leptospirosis in Sri Lanka?
AGAMPODI SB, KARUNARATHNA D, JAYATHILALA N, RATHNAYAKA H, AGAMPODI TC, KARUNANAYAKA L. Outbreak of leptospirosis after white-water rafting: sign of a shift from rural to recreational leptospirosis in Sri Lanka? Epidemiology And Infection 2013, 142: 843-846. PMID: 23800619, PMCID: PMC9151153, DOI: 10.1017/s0950268813001465.Peer-Reviewed Original ResearchConceptsMAT titresPositive IgM ELISAClassical clinical featuresAnti-leptospiral antibodiesHistory of leptospirosisOutbreak of leptospirosisEpidemiology of leptospirosisAfebrile patientsClinical featuresAcute leptospirosisFever patientsIgM ELISAAffluent urban populationsOccupational hazardsOutbreak investigationLeptospirosisLeptospirosis outbreaksOffice workersPatientsTitresWeeksExposureParticipantsOutbreakRecreational activities
2011
Leptospirosis Outbreak in Sri Lanka in 2008: Lessons for Assessing the Global Burden of Disease
Agampodi SB, Peacock SJ, Thevanesam V, Nugegoda DB, Smythe L, Thaipadungpanit J, Craig SB, Burns MA, Dohnt M, Boonsilp S, Senaratne T, Kumara A, Palihawadana P, Perera S, Vinetz JM. Leptospirosis Outbreak in Sri Lanka in 2008: Lessons for Assessing the Global Burden of Disease. American Journal Of Tropical Medicine And Hygiene 2011, 85: 471-478. PMID: 21896807, PMCID: PMC3163869, DOI: 10.4269/ajtmh.2011.11-0276.Peer-Reviewed Original ResearchConceptsAcute renal failureLeptospirosis outbreaksCase fatality rateLimited diagnostic capacityDisease burden estimatesLaboratory diagnostic capabilitiesEndemic infectious diseasesCause of epidemicSerovars PyrogenesClinical characteristicsRenal failureHeart failurePatient populationMain complicationsCase definitionBurden estimatesGlobal burdenCase confirmationHigh titersInfectious diseasesDiagnostic capacityHigh endemicityReference groupLeptospira interrogansDisease