2023
FtsE, the Nucleotide Binding Domain of the ABC Transporter Homolog FtsEX, Regulates Septal PG Synthesis in E. coli.
Mallik S, Dodia H, Ghosh A, Srinivasan R, Good L, Raghav SK, Beuria TK. FtsE, the Nucleotide Binding Domain of the ABC Transporter Homolog FtsEX, Regulates Septal PG Synthesis in E. coli. Microbiol Spectr 2023, e0286322. PMID: 37014250, DOI: 10.1128/spectrum.02863-22.Peer-Reviewed Original Research
2022
Atypical nuclear envelope condensates linked to neurological disorders reveal nucleoporin-directed chaperone activities
Prophet SM, Rampello AJ, Niescier RF, Gentile JE, Mallik S, Koleske AJ, Schlieker C. Atypical nuclear envelope condensates linked to neurological disorders reveal nucleoporin-directed chaperone activities. Nature Cell Biology 2022, 24: 1630-1641. PMID: 36302970, PMCID: PMC10041656, DOI: 10.1038/s41556-022-01001-y.Peer-Reviewed Original Research
2021
Biochemical characterization of an E. coli cell division factor FtsE shows ATPase cycles similar to the NBDs of ABC-transporters
Mallick S, Kumar A, Dodia H, Alexander C, Vasudevan D, Beuria T. Biochemical characterization of an E. coli cell division factor FtsE shows ATPase cycles similar to the NBDs of ABC-transporters. Bioscience Reports 2021, 41: bsr20203034. PMID: 33320186, PMCID: PMC7791547, DOI: 10.1042/bsr20203034.Peer-Reviewed Original ResearchConceptsFtsEX complexPG hydrolysisABC transportersCytoplasmic loopBiochemical characterizationATPase cycleCouple ATP hydrolysisATP-binding siteATPase activityE. coliBacterial cell wallTransduce signalsInner membraneSequence similarityBacterial divisionSignal transductionPeptidoglycan layerMid cellATP hydrolysisCell wallSoluble expressionBiochemical propertiesFtsE.Direct interactionTransport molecules
2020
MazEF-rifampicin interaction suggests a mechanism for rifampicin induced inhibition of persisters.
Alexander C, Guru A, Pradhan P, Mallick S, Mahanandia NC, Subudhi BB, Beuria TK. MazEF-rifampicin interaction suggests a mechanism for rifampicin induced inhibition of persisters. BMC Mol Cell Biol 2020, 21: 73. PMID: 33109090, DOI: 10.1186/s12860-020-00316-8.Peer-Reviewed Original Research