2020
Effect of Afrezza on Glucose Dynamics During HCL Treatment
Galderisi A, Cohen N, Calhoun P, Kraemer K, Breton M, Weinzimer S, Cengiz E. Effect of Afrezza on Glucose Dynamics During HCL Treatment. Diabetes Care 2020, 43: 2146-2152. PMID: 32661108, PMCID: PMC7440894, DOI: 10.2337/dc20-0091.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, InhalationAdolescentAdultBlood GlucoseBlood Glucose Self-MonitoringCross-Over StudiesDiabetes Mellitus, Type 1Dose-Response Relationship, DrugEquipment and SuppliesFemaleGlycemic ControlHumansHypoglycemic AgentsInsulin Infusion SystemsInsulin, Regular, HumanMaleMealsPostprandial PeriodYoung AdultConceptsControl armPremeal bolusesPostprandial plasma glucose levelsPostprandial blood glucose controlPrimary efficacy outcomeRapid-acting insulinBlood glucose controlPlasma glucose levelsType 1 diabetesLater time pointsSequential mealsEfficacy outcomesPPG levelsSecondary outcomesGlycemic excursionsMeal studyGlucose controlSubcutaneous routeInsulin delivery systemsGlucose levelsGlucose metricsHigh doseStudy daysInsulin absorptionInsulin bolus
2001
Transferrin Is an Insulin-Like Growth Factor-Binding Protein-3 Binding Protein1
Weinzimer S, Gibson T, Collett-Solberg P, Khare A, Liu B, Cohen P. Transferrin Is an Insulin-Like Growth Factor-Binding Protein-3 Binding Protein1. The Journal Of Clinical Endocrinology & Metabolism 2001, 86: 1806-1813. PMID: 11297622, DOI: 10.1210/jcem.86.4.7380.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnimalsApoptosisCarrier ProteinsCell DivisionCells, CulturedDose-Response Relationship, DrugFluorescent Antibody TechniqueHumansInsulin-Like Growth Factor Binding Protein 3Insulin-Like Growth Factor Binding ProteinsIronKineticsMaleMicroscopy, ConfocalMuscle, SmoothProstatic NeoplasmsSheepTissue DistributionTransferrinUrinary BladderYeastsConceptsIGFBP-3IGFBP-3-induced apoptosisInsulin-like growth factorBladder smooth muscle cellsHuman liver complementary DNA libraryProstate cancer cellsSmooth muscle cellsImportant physiological effectsIGF actionBinding proteinProteins/receptorsMuscle cellsProtein 3Growth factorCancer cellsCell proliferationTF treatmentPhysiological effectsNegligible affinityHuman serumTransferrin Is an Insulin-Like Growth Factor-Binding Protein-3 Binding Protein
Weinzimer SA. Transferrin Is an Insulin-Like Growth Factor-Binding Protein-3 Binding Protein. The Journal Of Clinical Endocrinology & Metabolism 2001, 86: 1806-1813. DOI: 10.1210/jc.86.4.1806.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnimalsApoptosisCarrier ProteinsCell DivisionCells, CulturedDose-Response Relationship, DrugFluorescent Antibody TechniqueHumansInsulin-Like Growth Factor Binding Protein 3Insulin-Like Growth Factor Binding ProteinsIronKineticsMaleMicroscopy, ConfocalMuscle, SmoothProstatic NeoplasmsSheepTissue DistributionTransferrinUrinary BladderYeastsConceptsIGFBP-3IGFBP-3-induced apoptosisInsulin-like growth factorBladder smooth muscle cellsHuman liver complementary DNA libraryProstate cancer cellsSmooth muscle cellsImportant physiological effectsIGF actionBinding proteinProteins/receptorsMuscle cellsProtein 3Growth factorCancer cellsCell proliferationTF treatmentPhysiological effectsNegligible affinityHuman serum
2000
Human Papillomavirus Type 16 E7 Oncoprotein Binds and Inactivates Growth-Inhibitory Insulin-Like Growth Factor Binding Protein 3
Mannhardt B, Weinzimer S, Wagner M, Fiedler M, Cohen P, Jansen-Dürr P, Zwerschke W. Human Papillomavirus Type 16 E7 Oncoprotein Binds and Inactivates Growth-Inhibitory Insulin-Like Growth Factor Binding Protein 3. Molecular And Cellular Biology 2000, 20: 6483-6495. PMID: 10938125, PMCID: PMC86123, DOI: 10.1128/mcb.20.17.6483-6495.2000.Peer-Reviewed Original ResearchMeSH KeywordsApoptosisBlotting, NorthernCell DivisionCell LineCells, CulturedDose-Response Relationship, DrugFluorescent Antibody TechniqueGlutathione TransferaseHumansInsulin-Like Growth Factor Binding Protein 3KeratinocytesOncogene Proteins, ViralPapillomavirus E7 ProteinsPrecipitin TestsProtein BindingRecombinant Fusion ProteinsTime FactorsTransfectionTumor Cells, CulturedTumor Suppressor Protein p53Two-Hybrid System Techniques