2018
A Brain–Heart Biomarker for Epileptogenesis
Bahari F, Ssentongo P, Schiff S, Gluckman B. A Brain–Heart Biomarker for Epileptogenesis. Journal Of Neuroscience 2018, 38: 8473-8483. PMID: 30150365, PMCID: PMC6158692, DOI: 10.1523/jneurosci.1130-18.2018.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiomarkersBrainDisease Models, AnimalElectroencephalographyEpilepsyHeartHeart RateMaleMice, Inbred C57BLParasitic DiseasesConceptsBrain-heart interactionsBiomarkers of epileptogenesisDevelopment of epilepsyAutonomic cardiac activityIdentification of patientsPostinjury epilepsyPreventable sequelaeFirst seizureBrain insultsCortical dischargesMale miceEpileptogenesisMurine modelMouse modelCardiac rhythmReliable biomarkersEpilepsyChronic measurementTreatment developmentBiomarkersSuch treatmentCardiac activityTherapeutic purposesBrain activityPatients
2017
Expansion of C9ORF72 in amyotrophic lateral sclerosis correlates with brain-computer interface performance
Geronimo A, Sheldon K, Broach J, Simmons Z, Schiff S. Expansion of C9ORF72 in amyotrophic lateral sclerosis correlates with brain-computer interface performance. Scientific Reports 2017, 7: 8875. PMID: 28827593, PMCID: PMC5567164, DOI: 10.1038/s41598-017-08857-3.Peer-Reviewed Original ResearchConceptsAmyotrophic lateral sclerosisLateral sclerosisFrontotemporal dementiaExpansion of C9ORF72Multiple neurodegenerative disordersHealthy controlsSymptom ratesHigh prevalenceAltered pathologyNeurodegenerative disordersBrain functionPatientsC9orf72 geneSclerosisAbnormal expansionPersonalized assessmentPsychological changesRepeat expansionBrain-computer interface performanceFurther explorationBCI taskHexanucleotide GGGGCCDementiaPrevalencePathologyA Murine Model to Study Epilepsy and SUDEP Induced by Malaria Infection
Ssentongo P, Robuccio A, Thuku G, Sim D, Nabi A, Bahari F, Shanmugasundaram B, Billard M, Geronimo A, Short K, Drew P, Baccon J, Weinstein S, Gilliam F, Stoute J, Chinchilli V, Read A, Gluckman B, Schiff S. A Murine Model to Study Epilepsy and SUDEP Induced by Malaria Infection. Scientific Reports 2017, 7: 43652. PMID: 28272506, PMCID: PMC5341121, DOI: 10.1038/srep43652.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDeath, SuddenDisease Models, AnimalElectroencephalographyEpilepsyMalaria, CerebralMaleMicePlasmodium bergheiSurvival AnalysisConceptsCerebral malariaAnimal modelsStrain combinationsPrevention of epilepsySuch animal modelsSubsequent epilepsyNeurological sequelaeAdjunctive therapyPathophysiological mechanismsMalaria infectionUnexpected deathMurine modelEpilepsyPreclinical researchSUDEPMalariaGenetic backgroundMultiple miceEpileptogenesisSequelaeTherapyInfectionMiceSurvivorsPrevention
2016
Performance predictors of brain–computer interfaces in patients with amyotrophic lateral sclerosis
Geronimo A, Simmons Z, Schiff S. Performance predictors of brain–computer interfaces in patients with amyotrophic lateral sclerosis. Journal Of Neural Engineering 2016, 13: 026002. PMID: 26824590, DOI: 10.1088/1741-2560/13/2/026002.Peer-Reviewed Original Research
2011
A square root ensemble Kalman filter application to a motor-imagery brain-computer interface
Kamrunnahar M, Schiff S. A square root ensemble Kalman filter application to a motor-imagery brain-computer interface. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2011, 2011: 6385-6388. PMID: 22255799, PMCID: PMC5699860, DOI: 10.1109/iembs.2011.6091576.Peer-Reviewed Original Research
2010
Controversies in epilepsy: Debates held during the Fourth International Workshop on Seizure Prediction
Frei MG, Zaveri HP, Arthurs S, Bergey GK, Jouny CC, Lehnertz K, Gotman J, Osorio I, Netoff TI, Freeman WJ, Jefferys J, Worrell G, Le Van Quyen M, Schiff SJ, Mormann F. Controversies in epilepsy: Debates held during the Fourth International Workshop on Seizure Prediction. Epilepsy & Behavior 2010, 19: 4-16. PMID: 20708976, PMCID: PMC2943379, DOI: 10.1016/j.yebeh.2010.06.009.Peer-Reviewed Original ResearchCongresses as TopicElectroencephalographyEpilepsyHumansInternational CooperationPredictive Value of TestsFeature selection on movement imagery discrimination and attention detection
Dias N, Kamrunnahar M, Mendes P, Schiff S, Correia J. Feature selection on movement imagery discrimination and attention detection. Medical & Biological Engineering & Computing 2010, 48: 331-341. PMID: 20112135, PMCID: PMC2946110, DOI: 10.1007/s11517-010-0578-1.Peer-Reviewed Original Research
2009
Advances in the Application of Technology to Epilepsy: The CIMIT/NIO Epilepsy Innovation Summit
Schachter S, Guttag J, Schiff S, Schomer D, Contributors S. Advances in the Application of Technology to Epilepsy: The CIMIT/NIO Epilepsy Innovation Summit. Epilepsy & Behavior 2009, 16: 3-46. PMID: 19780225, PMCID: PMC8118381, DOI: 10.1016/j.yebeh.2009.06.028.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnticonvulsantsBrain MappingChildDrug ResistanceElectric Stimulation TherapyElectroencephalographyEngineeringEpilepsyHumansMagnetic Resonance ImagingMedical Laboratory ScienceMicroelectrodesNanoparticlesNeuronsNeurosurgeryNeurotoxinsPredictive Value of TestsSeizuresSpectroscopy, Near-InfraredTomography, Emission-Computed, Single-PhotonTomography, OpticalTranscranial Magnetic StimulationConceptsTreatment systemEvaluation of patientsTreatment of patientsGroup of cliniciansEpilepsy surgeryEngineering technologyFurther technological developmentEpilepsySeizure onset detectionPatientsEngineersSeizure predictionTechnologyApplicationsOnset detectionSurgeryCliniciansPhysiciansUnmetDiagnosisSeizure entrainment with polarizing low-frequency electric fields in a chronic animal epilepsy model
Sunderam S, Chernyy N, Peixoto N, Mason J, Weinstein S, Schiff S, Gluckman B. Seizure entrainment with polarizing low-frequency electric fields in a chronic animal epilepsy model. Journal Of Neural Engineering 2009, 6: 046009. PMID: 19602730, PMCID: PMC3057918, DOI: 10.1088/1741-2560/6/4/046009.Peer-Reviewed Original ResearchConceptsField postsynaptic potentialsAnimal epilepsy modelsNeural activitySimultaneous recordingSpontaneous seizuresHippocampal epilepsyVentral hippocampusEpilepsy modelLocal field potentialsPostsynaptic potentialsNeuronal excitabilityNeuronal activityModulatory effectsAnimal modelsSeizuresStatistical significanceStimulationField potentialsMultiple presentationsAnimalsCharacteristic patternEpilepsyHippocampusRecordingsExcitabilityOptimization of Electrode Channels in Brain Computer Interfaces
Kamrunnahar M, Dias N, Schiff S. Optimization of Electrode Channels in Brain Computer Interfaces. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2009, 2009: 6477-6480. PMID: 19964437, PMCID: PMC2859435, DOI: 10.1109/iembs.2009.5333585.Peer-Reviewed Original ResearchConceptsBrain-computer interfaceFeature classificationMotor imagery tasksComputer interfaceBCI applicationsLinear discriminant analysisFeature selection algorithmFeature selection techniquesStepwise feature selectionFeature selectionSelection algorithmSelection techniquesImagery tasksOptimization approachOptimal numberTaskDiscrimination errorsHuman scalp electroencephalographyChannel combinationsElectrode channelsClassificationOptimum numberReliable selectionTime dependence of stimulation/recording-artifact transfer function estimates for neural interface systems
Chernyy N, Schiff S, Gluckman B. Time dependence of stimulation/recording-artifact transfer function estimates for neural interface systems. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2009, 2009: 1380-1383. PMID: 19964759, PMCID: PMC5502111, DOI: 10.1109/iembs.2009.5334297.Peer-Reviewed Original ResearchConceptsControl systemElectrode interface propertiesLow-frequency electric fieldNeural interface systemInterface propertiesControl outputElectric fieldElectrical potential variationsElectrical currentTransfer function magnitudeImpedance changesSystem stateMeasurement pointsInterface systemFunction magnitudeNeural control systemSimultaneous measurementTime dependencePotential variationPropertiesStimulus artifactTransfer function estimatesSystemFilterCurrent
2008
Model-based Responses and Features in Brain Computer Interfaces
Kamrunnahar M, Dias N, Schiff S, Gluckman B. Model-based Responses and Features in Brain Computer Interfaces. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2008, 2008: 4482-4485. PMID: 19163711, DOI: 10.1109/iembs.2008.4650208.Peer-Reviewed Original ResearchConceptsBrain-computer interfaceMotor imagery tasksComputer interfaceClassification errorDifferent feature selection methodsLinear discriminant analysisFeature selection methodClassification of tasksDevelopment of BCIsImagery tasksFeature extractionHuman scalp electroencephalographySelection methodRight hand movementsTaskFilter algorithmEEG signalsNovel modelPrincipal component analysisControl systems theoryHand movementsScalp EEG correlatesFeaturesInterfaceAlgorithm
2007
Improved sleep–wake and behavior discrimination using MEMS accelerometers
Sunderam S, Chernyy N, Peixoto N, Mason J, Weinstein S, Schiff S, Gluckman B. Improved sleep–wake and behavior discrimination using MEMS accelerometers. Journal Of Neuroscience Methods 2007, 163: 373-383. PMID: 17481736, PMCID: PMC2279268, DOI: 10.1016/j.jneumeth.2007.03.007.Peer-Reviewed Original ResearchComparison of EEG Pattern Classification Methods for Brain-Computer Interfaces
Dias N, Kamrunnahar M, Mendes P, Schiff S, Correia J. Comparison of EEG Pattern Classification Methods for Brain-Computer Interfaces. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2007, 2007: 2540-2543. PMID: 18002512, DOI: 10.1109/iembs.2007.4352846.Peer-Reviewed Original Research
2006
Seizure Modulation with Applied Electric Fields in Chronically Implanted Animals
Sunderam S, Chernyy N, Mason J, Peixoto N, Weinstein S, Schiff S, Gluckman B. Seizure Modulation with Applied Electric Fields in Chronically Implanted Animals. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2006, 2006: 1612-1615. PMID: 17946910, PMCID: PMC3547984, DOI: 10.1109/iembs.2006.259454.Peer-Reviewed Original Research
2005
Dangerous phase
Schiff S. Dangerous phase. Neuroinformatics 2005, 3: 315-317. PMID: 16284414, PMCID: PMC1469234, DOI: 10.1385/ni:3:4:315.Peer-Reviewed Original ResearchNeuronal spatiotemporal pattern discrimination: The dynamical evolution of seizures
Schiff S, Sauer T, Kumar R, Weinstein S. Neuronal spatiotemporal pattern discrimination: The dynamical evolution of seizures. NeuroImage 2005, 28: 1043-1055. PMID: 16198127, PMCID: PMC2078330, DOI: 10.1016/j.neuroimage.2005.06.059.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlgorithmsDiscrimination, PsychologicalElectroencephalographyHumansLinear ModelsMagnetoencephalographyModels, StatisticalPattern Recognition, VisualSeizuresControl of Traveling Waves in the Mammalian Cortex
Richardson K, Schiff S, Gluckman B. Control of Traveling Waves in the Mammalian Cortex. Physical Review Letters 2005, 94: 028103. PMID: 15698234, PMCID: PMC1513188, DOI: 10.1103/physrevlett.94.028103.Peer-Reviewed Original ResearchMultivariate linear discrimination of seizures
Jerger K, Weinstein S, Sauer T, Schiff S. Multivariate linear discrimination of seizures. Clinical Neurophysiology 2005, 116: 545-551. PMID: 15721068, DOI: 10.1016/j.clinph.2004.08.023.Peer-Reviewed Original Research
2003
Interplay of Electroencephalogram Phase and Auditory-Evoked Neural Activity
Kruglikov S, Schiff S. Interplay of Electroencephalogram Phase and Auditory-Evoked Neural Activity. Journal Of Neuroscience 2003, 23: 10122-10127. PMID: 14602828, PMCID: PMC6740863, DOI: 10.1523/jneurosci.23-31-10122.2003.Peer-Reviewed Original Research