The dynamics of brain and cerebrospinal fluid growth in normal versus hydrocephalic mice.
Mandell J, Neuberger T, Drapaca C, Webb A, Schiff S. The dynamics of brain and cerebrospinal fluid growth in normal versus hydrocephalic mice. Journal Of Neurosurgery Pediatrics 2010, 6: 1-10. PMID: 20593980, DOI: 10.3171/2010.4.peds1014.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAlgorithmsAnimalsAnimals, NewbornBrainCephalometryCerebral AqueductCerebral VentriclesDisease Models, AnimalFourier AnalysisFrontal LobeHydrocephalusImage Processing, Computer-AssistedImaging, Three-DimensionalIntracranial PressureLateral VentriclesMagnetic Resonance ImagingMathematical ComputingMiceMice, Inbred C57BLOccipital LobeOrgan SizeReference ValuesConceptsHydrocephalic miceBrain volumeClinical outcomesBrain growthVentricle volumeDynamics of brainCortical mantle thicknessPatterns of hydrocephalusOccipital horn ratioAccumulation of CSFTransmantle pressure gradientGrowth of brainVentricular ruptureParenchymal edemaVentricular sizeC57BL/6 miceTotal brainPercutaneous injectionAdjunct useHead circumferenceNormal miceCisterna magnaCSF volumeCognitive functionSerial quantification