2014
Oxygen and seizure dynamics: II. Computational modeling
Wei Y, Ullah G, Ingram J, Schiff S. Oxygen and seizure dynamics: II. Computational modeling. Journal Of Neurophysiology 2014, 112: 213-223. PMID: 24671540, PMCID: PMC4064403, DOI: 10.1152/jn.00541.2013.Peer-Reviewed Original ResearchConceptsSeizure eventsTissue oxygen pressureIntense neuronal firingSeizure patternsInhibitory neuronsNeuronal firingEpileptic seizuresSeizuresElectrophysiological recordingsOxygen metabolismSeizure dynamicsMetabolic energy consumptionEnergy metabolismExcitatoryMicroenvironment dynamicsRecent studies
2010
Assimilating Seizure Dynamics
Ullah G, Schiff S. Assimilating Seizure Dynamics. PLOS Computational Biology 2010, 6: e1000776. PMID: 20463875, PMCID: PMC2865517, DOI: 10.1371/journal.pcbi.1000776.Peer-Reviewed Original ResearchConceptsModern control theoryDynamics of networksDynamical systemsControl theoryUnmeasured partDynamical interactionsData assimilationSmall neuronal networksPhysical variablesDynamicsBrain dynamicsComputational modelSeizure dynamicsActual measurementsNeuronal networksMicroenvironment dynamicsObservabilityNetworkVariablesModelTheorySystemMeasurements
2009
The influence of sodium and potassium dynamics on excitability, seizures, and the stability of persistent states: I. Single neuron dynamics
Cressman J, Ullah G, Ziburkus J, Schiff S, Barreto E. The influence of sodium and potassium dynamics on excitability, seizures, and the stability of persistent states: I. Single neuron dynamics. Journal Of Computational Neuroscience 2009, 26: 159-170. PMID: 19169801, PMCID: PMC2704057, DOI: 10.1007/s10827-008-0132-4.Peer-Reviewed Original ResearchConceptsSingle neuron dynamicsDetailed bifurcation analysisLarge amplitude oscillationsExtracellular ion concentration dynamicsMathematical modelBifurcation analysisDynamical mechanismIon concentration dynamicsNeuron dynamicsReasonable approximationFull modelCompanion paperDynamicsImportant fundamental processesConcentration dynamics
2008
The influence of sodium and potassium dynamics on excitability, seizures, and the stability of persistent states: II. Network and glial dynamics
Ullah G, Cressman Jr. J, Barreto E, Schiff S. The influence of sodium and potassium dynamics on excitability, seizures, and the stability of persistent states: II. Network and glial dynamics. Journal Of Computational Neuroscience 2008, 26: 171-183. PMID: 19083088, PMCID: PMC2951284, DOI: 10.1007/s10827-008-0130-6.Peer-Reviewed Original Research
1985
Hyperexcitability following moderate hypoxia in hippocampal tissue slices
Schiff S, Somjen G. Hyperexcitability following moderate hypoxia in hippocampal tissue slices. Brain Research 1985, 337: 337-340. PMID: 2992681, DOI: 10.1016/0006-8993(85)90071-x.Peer-Reviewed Original Research