2014
Oxygen and seizure dynamics: I. Experiments
Ingram J, Zhang C, Cressman J, Hazra A, Wei Y, Koo Y, Žiburkus J, Kopelman R, Xu J, Schiff S. Oxygen and seizure dynamics: I. Experiments. Journal Of Neurophysiology 2014, 112: 205-212. PMID: 24598521, PMCID: PMC4064411, DOI: 10.1152/jn.00540.2013.Peer-Reviewed Original ResearchConceptsEpileptiform activityRat hippocampal slicesLayer-specific patternsSeizure-like eventsSeizure-like stateSpontaneous seizure-like eventsHippocampal slicesSeizure onsetNeuronal interplayCellular excitabilitySeizure dynamicsEndogenous hypoxiaGreater reductionO2 utilizationHypoxiaElectrical recordingsSeizuresCA1ExcitabilityPyramidale
1987
The effect of graded hypoxia on the hippocampal slice: an in vitro model of the ischemic penumbra.
Schiff S, Somjen G. The effect of graded hypoxia on the hippocampal slice: an in vitro model of the ischemic penumbra. Stroke 1987, 18: 30-37. PMID: 3027927, DOI: 10.1161/01.str.18.1.30.Peer-Reviewed Original ResearchConceptsMild hypoxiaSynaptic transmissionModerate hypoxiaHippocampal slicesGrade of hypoxiaHypoxic brain tissueExtracellular DC potentialDegree of hypoxiaPosthypoxic hyperexcitabilityIschemic penumbraExtracellular calciumExtracellular potassiumSynaptic functionBrain tissueHypoxiaHyperexcitabilityExtracellular pHSlicesSevere depolarizationNeuronsDC potentialResponse
1986
Selective neuronal vulnerability to hypoxia in vitro
Aitken P, Schiff S. Selective neuronal vulnerability to hypoxia in vitro. Neuroscience Letters 1986, 67: 92-96. PMID: 3014393, DOI: 10.1016/0304-3940(86)90215-6.Peer-Reviewed Original Research
1985
Overshoot of oxygen pressure in post-hypoxic brain tissue: a re-evaluation
Schiff S, Somjen G. Overshoot of oxygen pressure in post-hypoxic brain tissue: a re-evaluation. Brain Research 1985, 344: 150-153. PMID: 4041862, DOI: 10.1016/0006-8993(85)91200-4.Peer-Reviewed Original ResearchGlutamine can enhance synaptic transmission in hippocampal slices
Schiff S, Szerb J, Somjen G. Glutamine can enhance synaptic transmission in hippocampal slices. Brain Research 1985, 343: 366-369. PMID: 2996699, DOI: 10.1016/0006-8993(85)90758-9.Peer-Reviewed Original Research