2023
Increasing Spiritual Beliefs are Associated With Lower HIV Incidence Among Black Men Who Have Sex With Men: Results From HPTN 061 Longitudinal Study
Ransome Y, Taggart T, Huang A, Vermund S, Mayer K, Nunn A. Increasing Spiritual Beliefs are Associated With Lower HIV Incidence Among Black Men Who Have Sex With Men: Results From HPTN 061 Longitudinal Study. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2023, 94: 196-202. PMID: 37850978, DOI: 10.1097/qai.0000000000003278.Peer-Reviewed Original ResearchConceptsHIV seroconversionHIV incidenceBehavioral HIV prevention interventionsLower HIV incidenceProportional hazards regressionHIV prevention interventionsBlack menSpiritual beliefsOne-unit increaseHazards regressionLongitudinal riskPrevention interventionsHIVBiomedical assessmentLower hazard rateLongitudinal studyMenMonthsSeroconversionLongitudinal analysisReligious service attendanceIncidenceBaselineBMSMHigher proportion
2022
COVID-19 Clinical Presentation Among HIV-Infected Persons in China: A Systematic Review
Huang D, Zunong J, Li M, Li D, Gong J, Vermund SH, Hu Y. COVID-19 Clinical Presentation Among HIV-Infected Persons in China: A Systematic Review. Current HIV/AIDS Reports 2022, 19: 167-176. PMID: 35394249, PMCID: PMC8990500, DOI: 10.1007/s11904-022-00606-0.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedChinaCOVID-19COVID-19 TestingHIV InfectionsHumansMaleMiddle AgedPandemicsSARS-CoV-2Young AdultConceptsAntiretroviral therapyCOVID-19 clinical severityCOVID-19 clinical presentationCOVID-19Undetectable viral loadAsymptomatic COVID-19Severe COVID-19Last clinical visitCase series/reportsCase fatality rateCOVID-19 prognosisLate antiretroviral therapyIL-6 resultsSARS-CoV-2COVID-19 diagnosisMedian CD4Gastrointestinal symptomsHIV infectionMedian ageRespiratory distressClinical featuresClinical presentationClinical visitsViral loadClinical details
2021
Poor retention and care-related sex disparities among youth living with HIV in rural Mozambique
Ahonkhai AA, Aliyu MH, Audet CM, Bravo M, Simmons M, Claquin G, Memiah P, Fernando AN, Carlucci JG, Shepherd BE, Van Rompaey S, Yu Z, Gong W, Vermund SH, Wester CW. Poor retention and care-related sex disparities among youth living with HIV in rural Mozambique. PLOS ONE 2021, 16: e0250921. PMID: 34019582, PMCID: PMC8139489, DOI: 10.1371/journal.pone.0250921.Peer-Reviewed Original ResearchConceptsHigher oddsCombination antiretroviral therapy (cART) initiationCox proportional hazards modelCare continuum outcomesComprehensive HIV programsPost-ART initiationYoung adults 15Antiretroviral therapy initiationRetrospective cohort studySex-related disparitiesMultivariable logistic regressionOne-year followProportional hazards modelYears of agePL femalesSex-related differencesART initiationAYA cohortTherapy initiationCohort studyContinuum outcomesHIV outcomesClinical visitsAdults 15HIV programsFactors associated with past HIV testing among men who have sex with men attending university in China: a cross-sectional study*
Ye R, Liu C, Tan S, Li J, Simoni JM, Turner D, Nelson LE, Vermund SH, Wang N, Qian HZ. Factors associated with past HIV testing among men who have sex with men attending university in China: a cross-sectional study*. Sexual Health 2021, 18: 58-63. PMID: 33639685, PMCID: PMC10767712, DOI: 10.1071/sh20088.Peer-Reviewed Original ResearchConceptsPast HIV testingHIV testing ratesLog-binomial modelsHIV testingStudent MSMTesting ratesMultivariable log-binomial modelsBackground HIV prevalenceHIV testing experiencePositive HIV diagnosisIntervention clinical trialsLow HIV riskCross-sectional studySelf-reported barriersFirst sexual intercourseHIV diagnosisHIV testMedian ageHIV prevalenceClinical trialsHIV riskMSM participantsPositive diagnosisOlder ageBaseline survey
2020
Social Distancing among Medical Students during the 2019 Coronavirus Disease Pandemic in China: Disease Awareness, Anxiety Disorder, Depression, and Behavioral Activities
Xiao H, Shu W, Li M, Li Z, Tao F, Wu X, Yu Y, Meng H, Vermund SH, Hu Y. Social Distancing among Medical Students during the 2019 Coronavirus Disease Pandemic in China: Disease Awareness, Anxiety Disorder, Depression, and Behavioral Activities. International Journal Of Environmental Research And Public Health 2020, 17: 5047. PMID: 32674285, PMCID: PMC7399842, DOI: 10.3390/ijerph17145047.Peer-Reviewed Original ResearchConceptsMultivariable logistic regressionAnxiety disordersAnxiety disorder/depressionLogistic regressionNation-wide cross-sectional surveyGeneralized Anxiety Disorder-7Anxiety Disorder-7Cross-sectional surveySelf-administered questionnaireCoronavirus disease (COVID-19) pandemicMedical students' knowledgeQuestionnaire-9Medical studentsDisease awarenessSocial distancingCoronavirus diseaseDisease controlViral spreadCOVID-19 awarenessDisease pandemicPsychological supportDepressionDisordersDaily handwashingSocial distancing measures
2019
Effect of Universal Testing and Treatment on HIV Incidence — HPTN 071 (PopART)
Hayes RJ, Donnell D, Floyd S, Mandla N, Bwalya J, Sabapathy K, Yang B, Phiri M, Schaap A, Eshleman SH, Piwowar-Manning E, Kosloff B, James A, Skalland T, Wilson E, Emel L, Macleod D, Dunbar R, Simwinga M, Makola N, Bond V, Hoddinott G, Moore A, Griffith S, Deshmane Sista N, Vermund SH, El-Sadr W, Burns DN, Hargreaves JR, Hauck K, Fraser C, Shanaube K, Bock P, Beyers N, Ayles H, Fidler S. Effect of Universal Testing and Treatment on HIV Incidence — HPTN 071 (PopART). New England Journal Of Medicine 2019, 381: 207-218. PMID: 31314965, PMCID: PMC6587177, DOI: 10.1056/nejmoa1814556.Peer-Reviewed Original ResearchConceptsHIV-positive participantsViral suppressionHIV infectionGroup BGroup AGroup CMonth 12Universal testingPrevention interventionsPopulation cohortHuman immunodeficiency virus (HIV) infectionHome-based HIV testingBaseline HIV prevalenceCombination prevention interventionsImmunodeficiency virus infectionHIV-positive adultsPopulation-level incidenceNew HIV infectionsAdjusted rate ratiosCommunity-randomized trialLack of effectHIV carePrevious trial resultsStandard careART adherenceSyphilis associated with recreational drug use, depression and high-risk sexual behaviour in men who have sex with men: a case–control study in China
Wu H, Xiu C, Fu X, Li M, Wang Z, Li X, Wu J, Vermund SH, Hu Y. Syphilis associated with recreational drug use, depression and high-risk sexual behaviour in men who have sex with men: a case–control study in China. Sexually Transmitted Infections 2019, 95: 267. PMID: 30842346, PMCID: PMC11093516, DOI: 10.1136/sextrans-2018-053878.Peer-Reviewed Original ResearchConceptsRecreational drug useHigh-risk sexual behaviorCase-control studyDrug useSyphilis infectionToluidine red unheated serum testUnmatched case-control studyRed unheated serum testMultivariable logistic regressionPotential risk factorsMultiple drug useSexual behaviorPrior STIFrequent methamphetamine useSyphilis prevalenceSyphilis testingRisk factorsSerum testHealth workersDepression scoresSelf-administrated questionnaireRecreational drugsLogistic regressionSyphilisMethamphetamine use
2018
Surveillance of Maternal Syphilis in China: Pregnancy Outcomes and Determinants of Congenital Syphilis
Zhang X, Yu Y, Yang H, Xu H, Vermund SH, Liu K. Surveillance of Maternal Syphilis in China: Pregnancy Outcomes and Determinants of Congenital Syphilis. Medical Science Monitor 2018, 24: 7727-7735. PMID: 30370903, PMCID: PMC6216479, DOI: 10.12659/msm.910216.Peer-Reviewed Original ResearchConceptsAdverse pregnancy outcomesPregnancy outcomesCongenital syphilisPregnant womenFirst antenatal care visitEligible pregnant womenPrevention of motherAntenatal care visitsIndependent risk factorMultivariable regression analysisLogistic regression analysisRegression analysisChild transmissionMaternal syphilisAntenatal careCare visitsNeonatal asphyxiaNeonatal deathFirst trimesterRisk womenAntibody titersAntenatal testingEpidemiological characteristicsRisk factorsSyphilis diagnosisExploration of Implementation Patterns and Content from a Text-Based Outreach Intervention Clinical Trial for Newly Diagnosed, HIV-Positive MSM in Beijing, China
Knudson A, Shaw S, Yin L, Xiao D, Qian HZ, Sullivan S, Liu H, Ruan Y, Shao Y, Vermund SH, Amico KR. Exploration of Implementation Patterns and Content from a Text-Based Outreach Intervention Clinical Trial for Newly Diagnosed, HIV-Positive MSM in Beijing, China. AIDS And Behavior 2018, 23: 1158-1165. PMID: 30288683, PMCID: PMC6566097, DOI: 10.1007/s10461-018-2287-y.Peer-Reviewed Original ResearchHIV-1 Transmission Clustering and Phylodynamics Highlight the Important Role of Young Men Who Have Sex with Men
Dennis AM, Volz E, Frost A, Hossain M, Poon AFY, Rebeiro P, Vermund SH, Sterling TR, Kalish ML. HIV-1 Transmission Clustering and Phylodynamics Highlight the Important Role of Young Men Who Have Sex with Men. AIDS Research And Human Retroviruses 2018, 34: 879-888. PMID: 30027754, PMCID: PMC6204570, DOI: 10.1089/aid.2018.0039.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsCluster AnalysisCross-Sectional StudiesFemaleGenotypeHIV InfectionsHIV-1Homosexuality, MaleHumansMaleMiddle AgedMolecular EpidemiologyPhylogenyPol Gene Products, Human Immunodeficiency VirusRetrospective StudiesRisk FactorsRNA, ViralSequence Analysis, DNATennesseeYoung AdultConceptsYoung MSMTransmission clustersHIV-1 pol sequencesTransmission riskComprehensive Care ClinicHIV transmission patternsVanderbilt Comprehensive Care ClinicYears of ageHIV molecular epidemiologyCross-sectional analysisHigh transmission riskClinical factorsCare clinicsRisk ratioClinical dataImportance of interventionsMSM riskPol sequencesTransmission clusteringYounger ageRisk behaviorsLogistic regressionMolecular epidemiologyMSMYoung menRisk Prediction Score for HIV Infection: Development and Internal Validation with Cross-Sectional Data from Men Who Have Sex with Men in China
Yin L, Zhao Y, Peratikos MB, Song L, Zhang X, Xin R, Sun Z, Xu Y, Zhang L, Hu Y, Hao C, Ruan Y, Shao Y, Vermund SH, Qian HZ. Risk Prediction Score for HIV Infection: Development and Internal Validation with Cross-Sectional Data from Men Who Have Sex with Men in China. AIDS And Behavior 2018, 22: 2267-2276. PMID: 29786768, PMCID: PMC7024582, DOI: 10.1007/s10461-018-2129-y.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAlcohol DrinkingChinaCondomsCross-Sectional StudiesHIV InfectionsHomosexuality, MaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisPrevalenceRisk AssessmentRisk FactorsRisk-TakingSafe SexSexual and Gender MinoritiesSexual BehaviorSexual PartnersSurveys and QuestionnairesSyphilisUnsafe SexYoung AdultConceptsHIV infectionRisk scoreHuman immunodeficiency virus (HIV) riskMultivariable logistic regression modelingBootstrap-corrected C-indexMultiple male sexual partnersValid risk scoreVaccine clinical trialsHigh-risk MSMHigh-risk personsRisk prediction scoreReceptive anal intercourseReceptive anal sexInconsistent condom useMale sexual partnersHIV prevention programmingLogistic regression modelingDrug/alcohol addictionHIV acquisitionRisk reduction programsSyphilis infectionHIV prevalenceClinical trialsC-indexIllegal drug use
2017
Differences in health-related quality of life between HIV-positive and HIV-negative people in Zambia and South Africa: a cross-sectional baseline survey of the HPTN 071 (PopART) trial
Thomas R, Burger R, Harper A, Kanema S, Mwenge L, Vanqa N, Bell-Mandla N, Smith P, Floyd S, Bock P, Ayles H, Beyers N, Donnell D, Fidler S, Hayes R, Hauck K, Team H, Hargreaves J, Watson-Jones D, Godfrey-Faussett P, Cori A, Pickles M, Mandla N, Yang B, James A, Vermaak R, Makola N, Hoddinott G, Naidoo V, Bond V, Simwinga M, Mwinga A, Kosloff B, Limbada M, Bwalya J, Ngulube C, Fraser C, Eshleman S, Agyei Y, Cummings V, Catalano D, Emel L, Bunts L, Noble H, Burns D, Kouda A, Sista N, Moore A, White R, Headen T, Miller E, Hinson K, Vermund S, Barnes M, Horn L, Mwango A, Baldwin M, Wolf S, Hughes E. Differences in health-related quality of life between HIV-positive and HIV-negative people in Zambia and South Africa: a cross-sectional baseline survey of the HPTN 071 (PopART) trial. The Lancet Global Health 2017, 5: e1133-e1141. PMID: 28964756, PMCID: PMC5640509, DOI: 10.1016/s2214-109x(17)30367-4.Peer-Reviewed Original ResearchConceptsHIV-negative peopleHIV-positive individualsHIV-negative individualsAntiretroviral therapyHealth-related qualityHIV careHRQoL scoresHIV statusHerpes simplex virus type-2 statusNational InstituteHPTN 071 (PopART) studyHPTN 071 (PopART) trialLaboratory-confirmed HIVType 2 statusCross-sectional baseline surveyLarge cross-sectional surveyRecreational drug useCross-sectional surveyPresident's Emergency PlanGeneral population sampleHRQoL informationBetter HRQoLHIV-negativeHIV progressionHRQoL dataMonitoring Anesthesia Care Delivery and Perioperative Mortality in Kenya Utilizing a Provider-driven Novel Data Collection Tool
Sileshi B, Newton MW, Kiptanui J, Shotwell MS, Wanderer JP, Mungai M, Scherdin J, Harris PA, Vermund SH, Sandberg WS, McEvoy MD. Monitoring Anesthesia Care Delivery and Perioperative Mortality in Kenya Utilizing a Provider-driven Novel Data Collection Tool. Anesthesiology 2017, 127: 250-271. PMID: 28657959, PMCID: PMC5519082, DOI: 10.1097/aln.0000000000001713.Peer-Reviewed Original ResearchConceptsPerioperative dataPerioperative mortality rateTertiary referral hospitalMortality rate differencesAnesthesia care deliveryLogistic regression modelsMiddle-income settingsPerioperative mortalityCesarean deliveryEmergency surgeryMiddle-income countriesPerioperative careReferral hospitalSurgery typeSingle centerProcedure typeGeneral surgeryHigh riskMortality rateCare deliveryMortalityData collection periodData collection toolSurgeryRegression modelsThe introduction of new policies and strategies to reduce inequities and improve child health in Kenya: A country case study on progress in child survival, 2000-2013
Brault MA, Ngure K, Haley CA, Kabaka S, Sergon K, Desta T, Mwinga K, Vermund SH, Kipp AM. The introduction of new policies and strategies to reduce inequities and improve child health in Kenya: A country case study on progress in child survival, 2000-2013. PLOS ONE 2017, 12: e0181777. PMID: 28763454, PMCID: PMC5538680, DOI: 10.1371/journal.pone.0181777.Peer-Reviewed Original ResearchMeSH KeywordsAdultChild HealthChild Health ServicesChild MortalityChild, PreschoolFemaleFocus GroupsHealth PolicyHealth Status DisparitiesHealthcare DisparitiesHIV InfectionsHumansInfantInfant MortalityInfant, NewbornInfectious Disease Transmission, VerticalKenyaMaleMaternal Health ServicesNeonatologyObstetricsPregnancyRural PopulationUrban PopulationYoung AdultConceptsCommunity health strategyNew policiesAFRO regionQualitative dataCountry case studiesUser feesChild survivalDepth case studyMillennium Development GoalsInsufficient progressEssential packageFour-country studyCase studyPolicies/strategiesKenya's effortsPolicy reviewDevelopment GoalsHealth strategiesNational documentsNeonatal careGeographic inequitiesInequitiesKey barriersProvision of immunizationsAfrican regionAdolescents, young people, and the 90–90–90 goals
Wong VJ, Murray KR, Phelps BR, Vermund SH, McCarraher DR. Adolescents, young people, and the 90–90–90 goals. AIDS 2017, 31: s191-s194. PMID: 28665876, PMCID: PMC5497776, DOI: 10.1097/qad.0000000000001539.Peer-Reviewed Original ResearchConceptsHIV testingTreatment initiationJoint United Nations ProgrammeYoung people ages 15People ages 15AIDS 90HIV diagnosisUnited Nations ProgrammePrimary preventionEarly diagnosisHIVNew infectionsAge 15Nations ProgrammeDiagnosisEpidemic controlAdolescentsProgram plannersCurrent low ratesLower ratesYoung peopleNumber of youthRecent studiesTreatmentInitiationHIV status disclosure, facility-based delivery and postpartum retention of mothers in a prevention clinical trial in rural Nigeria
Sarko KA, Blevins M, Ahonkhai AA, Audet CM, Moon TD, Gebi UI, Gana AM, Wester CW, Vermund SH, Aliyu MH. HIV status disclosure, facility-based delivery and postpartum retention of mothers in a prevention clinical trial in rural Nigeria. International Health 2017, 9: 243-251. PMID: 28810669, PMCID: PMC5881261, DOI: 10.1093/inthealth/ihx023.Peer-Reviewed Original ResearchConceptsHIV status disclosureFacility-based deliveryPostpartum retentionStatus disclosureHIV statusIntervention armWeeks postpartumChild HIV transmission (PMTCT) trialTrial intervention armPrevention of motherUnknown HIV statusPrevention clinical trialsMixed-effects logistic regressionEffects logistic regressionPMTCT continuumHIV careTreatment-naïveAntenatal carePregnant womenFacility deliveryMaternal ageObstetric servicesCare measuresClinical trialsHealth facilitiesNonacademic Attributes Predict Medical and Nursing Student Intentions to Emigrate or to Work Rurally: An Eight-Country Survey in Asia and Africa.
Silvestri DM, Blevins M, Wallston KA, Afzal AR, Alam N, Andrews B, Derbew M, Kaur S, Mipando M, Mkony CA, Mwachaka PM, Ranjit N, Vermund SH. Nonacademic Attributes Predict Medical and Nursing Student Intentions to Emigrate or to Work Rurally: An Eight-Country Survey in Asia and Africa. American Journal Of Tropical Medicine And Hygiene 2017, 96: 1512-1520. PMID: 28719284, PMCID: PMC5462594, DOI: 10.4269/ajtmh.16-0756.Peer-Reviewed Original ResearchAdapting an adherence support workers intervention: engaging traditional healers as adherence partners for persons enrolled in HIV care and treatment in rural Mozambique
Audet CM, Salato J, Vermund SH, Amico KR. Adapting an adherence support workers intervention: engaging traditional healers as adherence partners for persons enrolled in HIV care and treatment in rural Mozambique. Implementation Science 2017, 12: 50. PMID: 28407813, PMCID: PMC5390357, DOI: 10.1186/s13012-017-0582-z.Peer-Reviewed Original ResearchConceptsCommunity health workersAntiretroviral therapyWorker interventionTraditional healersHealth workersHealth systemAllopathic health systemEvidence-informed interventionsLow-literacy populationsHIV careHIV diagnosisRural MozambiquePatient adherenceHIV epidemicHealth facilitiesClinical careHealthcare providersHealth workforceHIVTraditional treatmentCommunity-based activitiesInterventionTraditional medicineCareSuccessful program implementationThe case for integrated human papillomavirus vaccine and HIV prevention with broader sexual and reproductive health and rights services for adolescent girls and young women
Narasimhan M, Pedersen H, Ogilvie G, Vermund SH. The case for integrated human papillomavirus vaccine and HIV prevention with broader sexual and reproductive health and rights services for adolescent girls and young women. Transactions Of The Royal Society Of Tropical Medicine And Hygiene 2017, 111: 141-143. PMID: 28673020, PMCID: PMC6257065, DOI: 10.1093/trstmh/trx032.Peer-Reviewed Original Research
2016
Commercial sex and risk of HIV, syphilis, and herpes simplex virus-2 among men who have sex with men in six Chinese cities
Zheng C, Xu JJ, Hu QH, Yu YQ, Chu ZX, Zhang J, Han XX, Lu L, Wang Z, Fu JH, Chen X, Yan HJ, Jiang YJ, Geng WQ, Vermund SH, Qian HZ, Shang H. Commercial sex and risk of HIV, syphilis, and herpes simplex virus-2 among men who have sex with men in six Chinese cities. BMC Infectious Diseases 2016, 16: 765. PMID: 28003032, PMCID: PMC5178086, DOI: 10.1186/s12879-016-2130-x.Peer-Reviewed Original ResearchConceptsHIV/STIsHigh prevalenceHigh riskSex partnersHIV/STI surveillanceSimplex virus type 2HSV-2 infectionHIV/STISubgroups of MSMSimplex virus 2Male sex partnersCommercial sexRisk of HIVUnprotected anal intercourseVirus type 2Cross-sectional surveyHIV prevalenceSTI surveillanceHSV-2Overall prevalenceAnal intercourseHIVType 2Serological testsGreater risk