2021
Association between medical male circumcision and HIV risk compensation among heterosexual men: a systematic review and meta-analysis
Gao Y, Yuan T, Zhan Y, Qian HZ, Sun Y, Zheng W, Fu L, Liang B, Zhu Z, Ouyang L, Liu M, Fitzpatrick T, Wu Z, Meng X, Baeten JM, Zhao J, Vermund SH, Yu M, Wu G, Su B, Zou H. Association between medical male circumcision and HIV risk compensation among heterosexual men: a systematic review and meta-analysis. The Lancet Global Health 2021, 9: e932-e941. PMID: 33939956, PMCID: PMC8690595, DOI: 10.1016/s2214-109x(21)00102-9.Peer-Reviewed Original ResearchConceptsMedical male circumcisionHigh-risk sexual behaviorOdds ratioMultiple sex partnersSex partnersHIV infectionMale circumcisionMantel-Haenszel random-effects modelSystematic reviewCondom useHeterosexual menLow self-perceived riskAdjusted odds ratioSelf-perceived riskPooled odds ratioHIV preventive measuresMultiple sexual partnersSexual behaviorRandom-effects modelSexual health educationOriginal study dataCircumcision prevalenceCochrane LibrarySubgroup analysisEligible studies
2019
Treatment as Prevention: Concepts and Challenges for Reducing HIV Incidence
Brault MA, Spiegelman D, Hargreaves J, Nash D, Vermund SH. Treatment as Prevention: Concepts and Challenges for Reducing HIV Incidence. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2019, 82: s104-s112. PMID: 31658196, PMCID: PMC6820703, DOI: 10.1097/qai.0000000000002168.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyHIV transmissionHIV plasma loadReducing HIV IncidenceHIV prevention trialsCommunity-level interventionsDeployable vaccineViral suppressionHIV testingHIV incidencePrevention trialsUninfected personsChronic conditionsHIV investmentsEarly treatmentTreat strategySexual partnersViral expressionTransmission riskHIVTrialsTreatmentInconsistent findingsPreventionSaharan Africa
2018
Risk Prediction Score for HIV Infection: Development and Internal Validation with Cross-Sectional Data from Men Who Have Sex with Men in China
Yin L, Zhao Y, Peratikos MB, Song L, Zhang X, Xin R, Sun Z, Xu Y, Zhang L, Hu Y, Hao C, Ruan Y, Shao Y, Vermund SH, Qian HZ. Risk Prediction Score for HIV Infection: Development and Internal Validation with Cross-Sectional Data from Men Who Have Sex with Men in China. AIDS And Behavior 2018, 22: 2267-2276. PMID: 29786768, PMCID: PMC7024582, DOI: 10.1007/s10461-018-2129-y.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAlcohol DrinkingChinaCondomsCross-Sectional StudiesHIV InfectionsHomosexuality, MaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisPrevalenceRisk AssessmentRisk FactorsRisk-TakingSafe SexSexual and Gender MinoritiesSexual BehaviorSexual PartnersSurveys and QuestionnairesSyphilisUnsafe SexYoung AdultConceptsHIV infectionRisk scoreHuman immunodeficiency virus (HIV) riskMultivariable logistic regression modelingBootstrap-corrected C-indexMultiple male sexual partnersValid risk scoreVaccine clinical trialsHigh-risk MSMHigh-risk personsRisk prediction scoreReceptive anal intercourseReceptive anal sexInconsistent condom useMale sexual partnersHIV prevention programmingLogistic regression modelingDrug/alcohol addictionHIV acquisitionRisk reduction programsSyphilis infectionHIV prevalenceClinical trialsC-indexIllegal drug use
2017
HIV testing and sexual risks among migrant men who have sex with men: findings from a large cross-sectional study in Beijing, China
Liu Y, Vermund SH, Ruan Y, Liu H, Zhang C, Yin L, Shao Y, Qian HZ. HIV testing and sexual risks among migrant men who have sex with men: findings from a large cross-sectional study in Beijing, China. AIDS Care 2017, 30: 86-94. PMID: 28944685, PMCID: PMC6088860, DOI: 10.1080/09540121.2017.1381331.Peer-Reviewed Original ResearchConceptsLifetime male sexual partnersCondomless receptive anal sexHIV testingMigrant MSMHIV perceptionAnal sexHIV/syphilis infectionOlder ageLarge cross-sectional studyHIV/STI riskLikelihood of syphilisHIV/syphilisInsertive anal sexReceptive anal sexCross-sectional studyMale sexual partnersSyphilis infectionHIV transmissionLocal MSMSTI riskChinese MSMLower oddsEpidemiological studiesSexual partnersRisk profileHIV status disclosure, facility-based delivery and postpartum retention of mothers in a prevention clinical trial in rural Nigeria
Sarko KA, Blevins M, Ahonkhai AA, Audet CM, Moon TD, Gebi UI, Gana AM, Wester CW, Vermund SH, Aliyu MH. HIV status disclosure, facility-based delivery and postpartum retention of mothers in a prevention clinical trial in rural Nigeria. International Health 2017, 9: 243-251. PMID: 28810669, PMCID: PMC5881261, DOI: 10.1093/inthealth/ihx023.Peer-Reviewed Original ResearchConceptsHIV status disclosureFacility-based deliveryPostpartum retentionStatus disclosureHIV statusIntervention armWeeks postpartumChild HIV transmission (PMTCT) trialTrial intervention armPrevention of motherUnknown HIV statusPrevention clinical trialsMixed-effects logistic regressionEffects logistic regressionPMTCT continuumHIV careTreatment-naïveAntenatal carePregnant womenFacility deliveryMaternal ageObstetric servicesCare measuresClinical trialsHealth facilitiesSubsequent Sexual Risks Among Men Who Have Sex with Men May Differ by Sex of First Partner and Age at Sexual Debut: A Cross-Sectional Study in Beijing, China
Liu Y, Qian HZ, Amico KR, Liu H, Yin L, Ruan Y, Shao Y, Zhang C, Vermund SH. Subsequent Sexual Risks Among Men Who Have Sex with Men May Differ by Sex of First Partner and Age at Sexual Debut: A Cross-Sectional Study in Beijing, China. AIDS And Behavior 2017, 21: 2913-2923. PMID: 28110474, PMCID: PMC5522364, DOI: 10.1007/s10461-017-1677-x.Peer-Reviewed Original ResearchConceptsSexual debutSexual riskSyphilis riskAnal sexFirst sexLifetime female partnersLifetime male partnersHIV/syphilisInsertive anal sexReceptive anal sexCross-sectional studyRecent vaginal sexHIV riskChinese MSMMSM riskSubsequent sexual riskVaginal sexMale partnersFemale partnersSexMenWomenRiskSyphilisAge
2016
Commercial sex and risk of HIV, syphilis, and herpes simplex virus-2 among men who have sex with men in six Chinese cities
Zheng C, Xu JJ, Hu QH, Yu YQ, Chu ZX, Zhang J, Han XX, Lu L, Wang Z, Fu JH, Chen X, Yan HJ, Jiang YJ, Geng WQ, Vermund SH, Qian HZ, Shang H. Commercial sex and risk of HIV, syphilis, and herpes simplex virus-2 among men who have sex with men in six Chinese cities. BMC Infectious Diseases 2016, 16: 765. PMID: 28003032, PMCID: PMC5178086, DOI: 10.1186/s12879-016-2130-x.Peer-Reviewed Original ResearchConceptsHIV/STIsHigh prevalenceHigh riskSex partnersHIV/STI surveillanceSimplex virus type 2HSV-2 infectionHIV/STISubgroups of MSMSimplex virus 2Male sex partnersCommercial sexRisk of HIVUnprotected anal intercourseVirus type 2Cross-sectional surveyHIV prevalenceSTI surveillanceHSV-2Overall prevalenceAnal intercourseHIVType 2Serological testsGreater riskSubstance use and HIV-risk behaviors among HIV-positive men who have sex with men in China: repeated measures in a cohort study design
Zhang C, Liu Y, Sun X, Wang J, Lu HY, He X, Zhang H, Ruan YH, Shao Y, Vermund SH, Qian HZ. Substance use and HIV-risk behaviors among HIV-positive men who have sex with men in China: repeated measures in a cohort study design. AIDS Care 2016, 29: 644-653. PMID: 27832699, PMCID: PMC5350012, DOI: 10.1080/09540121.2016.1255709.Peer-Reviewed Original ResearchConceptsHIV risk behaviorsCohort study designSubstance useStudy designHIV-positive MSMHIV-positive menGeneralized Estimating Equation modelsFemale sex partnersRapid HIV transmissionMale sexual partnersRigorous study designsSexual risk behaviorsCurrent studySeronegative counterpartsSeropositive menSeropositive partnersHIV transmissionMean agePotential confoundersRisk factorsHigh riskRisk populationsSex partnersUnprotected sexRisk behaviorsAlcohol misuse, risky sexual behaviors, and HIV or syphilis infections among Chinese men who have sex with men
Liu Y, Ruan Y, Strauss SM, Yin L, Liu H, Amico KR, Zhang C, Shao Y, Qian HZ, Vermund SH. Alcohol misuse, risky sexual behaviors, and HIV or syphilis infections among Chinese men who have sex with men. Drug And Alcohol Dependence 2016, 168: 239-246. PMID: 27723554, PMCID: PMC5523945, DOI: 10.1016/j.drugalcdep.2016.09.020.Peer-Reviewed Original ResearchConceptsAlcohol Use Disorders Identification Test-ConsumptionSyphilis infectionBinge drinkersChinese menAlcohol misuseCondomless insertive anal intercourseHIV/syphilis infectionRecent alcohol misuseAlcohol risk reduction programCross-sectional studyInsertive anal intercourseAUDIT-C scoresCurrent alcohol dependenceInterviewer-administered surveyHigh-risk behaviorsRisk reduction programsRisky sexual behaviorMisuse MeasureHIV riskChinese MSMAnal intercourseHigh riskSyphilis riskBinge drinkingHazardous drinkersHigh HIV prevalence and the internet as a source of HIV-related service information at a community-based organization in Peru: a cross-sectional study of men who have sex with men
Passaro RC, Haley CA, Sanchez H, Vermund SH, Kipp AM. High HIV prevalence and the internet as a source of HIV-related service information at a community-based organization in Peru: a cross-sectional study of men who have sex with men. BMC Public Health 2016, 16: 871. PMID: 27557857, PMCID: PMC4997688, DOI: 10.1186/s12889-016-3561-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultCommunity Health ServicesCross-Sectional StudiesHIV InfectionsHomosexuality, MaleHumansInformation Seeking BehaviorInformation ServicesInternetLogistic ModelsMaleMarketing of Health ServicesOdds RatioPatient Acceptance of Health CarePeer GroupPeruPrevalenceRisk-TakingSex WorkersSexual BehaviorSexual PartnersYoung AdultConceptsHIV prevalenceHIV servicesCross-sectional studyHIV careCommunity-based organizationsMethodsA cross-sectional studyMultivariable logistic regression modelSource of HIVHigh-risk personsSex workersHigh HIV prevalenceGeneral adult populationSex workers groupSexual risk behaviorsResource-limited settingsLogistic regression modelsHIV diagnosisWorker groupsHigh riskAdult populationInfected individualsPerson groupRisk behaviorsRisk profileMSMFrequent HIV Testing
Liu Y, Qian HZ, Ruan Y, Wu P, Osborn CY, Jia Y, Yin L, Lu H, He X, Shao Y, Vermund SH. Frequent HIV Testing. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2016, 72: 452-461. PMID: 27003496, PMCID: PMC4925192, DOI: 10.1097/qai.0000000000001001.Peer-Reviewed Original ResearchConceptsMultivariable logistic regression analysisCurrent HIV infectionHIV incidence reductionHIV testing historyPropensity score adjustmentCubic spline modelingBorderline significant trendLogistic regression analysisHigher testing ratesHIV infectionHIV serostatusPrevious HIVHIV epidemicBeijing MSMTesting ratesScore adjustmentIncidence reductionTesting historyHIVInfection statusBehavioral factorsRegression analysisMSMOddsMenSeeking Male Sexual Partners via Internet and Traditional Venues among Chinese Men Who Have Sex with Men: Implications for HIV Risk Reduction Interventions
Liu Y, Wang J, Qian HZ, Liu H, Yin L, Lu H, Zhang C, Ruan Y, Shao Y, Vermund SH. Seeking Male Sexual Partners via Internet and Traditional Venues among Chinese Men Who Have Sex with Men: Implications for HIV Risk Reduction Interventions. AIDS And Behavior 2016, 20: 2222-2230. PMID: 27000143, PMCID: PMC7784627, DOI: 10.1007/s10461-016-1371-4.Peer-Reviewed Original ResearchConceptsMale sexual partnersChinese menSexual partnersHIV risk reduction interventionsCondomless receptive anal sexReceptive anal sexRisk reduction interventionsBehaviors of MSMCross-sectional surveyHigh-risk behaviorsHIV epidemicChinese MSMAnal sexReduction interventionsMSMSociodemographic predictorsLonger durationSexMenInterventionHigher incomeHIVTraditional venuesEngagement of Men in Antenatal Care Services: Increased HIV Testing and Treatment Uptake in a Community Participatory Action Program in Mozambique
Audet CM, Blevins M, Chire YM, Aliyu MH, Vaz LM, Antonio E, Alvim F, Bechtel R, Wester CW, Vermund SH. Engagement of Men in Antenatal Care Services: Increased HIV Testing and Treatment Uptake in a Community Participatory Action Program in Mozambique. AIDS And Behavior 2016, 20: 2090-2100. PMID: 26906021, PMCID: PMC4995150, DOI: 10.1007/s10461-016-1341-x.Peer-Reviewed Original ResearchConceptsAntenatal careHIV testingPregnant womenProvider-initiated counselingAntenatal care servicesAntiretroviral therapy servicesPre-post intervention designUptake of ARTTraditional birth attendantsMale engagementCommunity health agentsRate of testingANC servicesTreatment uptakeBirth attendantsService uptakePartner's pregnancyCare servicesTherapy servicesHealth agentsTreatment acceptabilityMale partnersSimilar interventionsMale championsPregnancyBarriers and Facilitators of Linkage to and Engagement in HIV Care Among HIV-Positive Men Who Have Sex with Men in China: A Qualitative Study
Liu Y, Osborn CY, Qian HZ, Yin L, Xiao D, Ruan Y, Simoni JM, Zhang X, Shao Y, Vermund SH, Amico KR. Barriers and Facilitators of Linkage to and Engagement in HIV Care Among HIV-Positive Men Who Have Sex with Men in China: A Qualitative Study. AIDS Patient Care And STDs 2016, 30: 70-77. PMID: 26784360, PMCID: PMC4753635, DOI: 10.1089/apc.2015.0296.Peer-Reviewed Original ResearchMeSH KeywordsAdultChinaConfidentialityFearFocus GroupsHealth Knowledge, Attitudes, PracticeHealth ServicesHealth Services AccessibilityHIV InfectionsHomosexuality, MaleHumansInterviews as TopicMalePeer GroupPrejudicePrevalenceQualitative ResearchRisk-TakingSexual PartnersSocial StigmaSocioeconomic FactorsConceptsHIV-positive MSMFacilitators of linkageHIV careAntiretroviral therapyCurrent HIV preventionFree HIV careHIV-positive patientsHIV-positive menHIV care servicesHealth care workersFocus group discussionsContinuum of careHIV transmissionCare interventionsHIV preventionClinic timeCare workersQualitative studyCare servicesKey populationsPsychological burdenMSMCarePeer referralDisclosure concerns
2015
Achieving Pregnancy Safely in HIV-Affected Individuals and Couples
Mmeje O, Njoroge B, Cohen CR, Temmerman M, Vermund SH, van der Poel S. Achieving Pregnancy Safely in HIV-Affected Individuals and Couples. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2015, 70: e155-e159. PMID: 26334740, PMCID: PMC10767706, DOI: 10.1097/qai.0000000000000814.Peer-Reviewed Original ResearchQualitative Assessment of Barriers and Facilitators of Access to HIV Testing Among Men Who Have Sex with Men in China
Liu Y, Sun X, Qian HZ, Yin L, Yan Z, Wang L, Jiang S, Lu H, Ruan Y, Shao Y, Vermund SH, Amico KR. Qualitative Assessment of Barriers and Facilitators of Access to HIV Testing Among Men Who Have Sex with Men in China. AIDS Patient Care And STDs 2015, 29: 481-489. PMID: 26186029, PMCID: PMC4553375, DOI: 10.1089/apc.2015.0083.Peer-Reviewed Original ResearchConceptsHIV testingHIV prevention intervention effortsLimited HIV knowledgeHIV testing ratesHIV-positive groupHigh-risk subgroupsDiagnosis of HIVHigh-risk behaviorsFacilitators of accessPrevention intervention effortsHIV careHIV servicesHIV knowledgeRisk subgroupsClinic timeNosocomial infectionsChinese MSMUltimate preventionFocus groupsTesting ratesOnward transmissionPositive diagnosisRapid linkageHIVIntervention development
2014
Recreational drug use and risks of HIV and sexually transmitted infections among Chinese men who have sex with men: Mediation through multiple sexual partnerships
Xu JJ, Zhang C, Hu QH, Chu ZX, Zhang J, Li YZ, Lu L, Wang Z, Fu JH, Chen X, Yan HJ, Zhuang MH, Jiang YJ, Geng WQ, Vermund SH, Shang H, Qian HZ. Recreational drug use and risks of HIV and sexually transmitted infections among Chinese men who have sex with men: Mediation through multiple sexual partnerships. BMC Infectious Diseases 2014, 14: 642. PMID: 25443542, PMCID: PMC4272794, DOI: 10.1186/s12879-014-0642-9.Peer-Reviewed Original ResearchConceptsMultiple sexual partnershipsUnprotected sexDrug useSexual partnersSexual partnershipsSimplex virus type 2Multiple logistic regression modelHSV-2 infectionHSV-2 prevalenceCross-sectional studyRisk of HIVMultiple sexual partnersVirus type 2Last sexual encounterRecreational drug useLogistic regression modelsHIV infectionActive MSMHSV-2HIV riskSexual disinhibitionChinese MSMHigh riskHIVChinese menSexual Risk Reduction for HIV-Infected Persons: A Meta-Analytic Review of “Positive Prevention” Randomized Clinical Trials
Yin L, Wang N, Vermund SH, Shepherd BE, Ruan Y, Shao Y, Qian HZ. Sexual Risk Reduction for HIV-Infected Persons: A Meta-Analytic Review of “Positive Prevention” Randomized Clinical Trials. PLOS ONE 2014, 9: e107652. PMID: 25243404, PMCID: PMC4171502, DOI: 10.1371/journal.pone.0107652.Peer-Reviewed Original ResearchConceptsRandomized clinical trialsStandardized mean differencePrevention interventionsSexual partnersClinical trialsUnknown status sexual partnersMonths of followShort-term efficacyLong-term efficacyPrevention intervention trialRandom-effects modelSexual risk reductionHIV/AIDSEffect sizeRisk reduction programsPrimary outcomeStudy armsIntervention armIntervention trialsSexual transmissionControl armLong-term effectsAnal intercourseElectronic databasesPLWHAHIV and syphilis prevalence trends among men who have sex with men in Guangxi, China: yearly cross-sectional surveys, 2008–2012
Wang X, Lan G, Shen Z, Vermund SH, Zhu Q, Chen Y, Khoshnood K, Wu Z, Tang Z. HIV and syphilis prevalence trends among men who have sex with men in Guangxi, China: yearly cross-sectional surveys, 2008–2012. BMC Infectious Diseases 2014, 14: 367. PMID: 24993252, PMCID: PMC4091643, DOI: 10.1186/1471-2334-14-367.Peer-Reviewed Original ResearchConceptsYears of ageSyphilis prevalenceCross-sectional surveyCurrent syphilisHIV prevalencePrevalence trendsSexual intercourseIncident HIV casesAnnual cross-sectional surveyRisk factor dataSignificant predictorsRisk of HIVNational sentinel surveillanceYearly cross-sectional surveysHIV/AIDSSyphilis infectionHIV infectionHIV casesSentinel surveillanceRisk factorsBlood samplesHIVKey populationsMSMPrevalenceHIV Risk Perception among HIV Negative or Status-Unknown Men Who Have Sex with Men in China
Fan W, Yin L, Qian HZ, Li D, Shao Y, Vermund SH, Ruan Y, Zhang Z. HIV Risk Perception among HIV Negative or Status-Unknown Men Who Have Sex with Men in China. BioMed Research International 2014, 2014: 232451. PMID: 24795880, PMCID: PMC3985141, DOI: 10.1155/2014/232451.Peer-Reviewed Original ResearchConceptsHIV risk perceptionSelf-perceived riskHIV infectionHigh riskMultivariate logistic regression modelLow self-perceived riskCross-sectional studySelf-reported historyHIV/AIDS epidemicIllicit drug useLogistic regression modelsHIV-negativeHIV testingHIV statusSyphilis testingBeijing MSMChinese MSMHIV perceptionBlood samplesLower riskDrug useHIVMSMUnknown statusAIDS epidemic