2022
Protocol for the pilot quasi-experimental controlled trial of a gender-responsive implementation strategy with providers to improve HIV outcomes in Uganda
Sileo K, Wanyenze R, Anecho A, Luttinen R, Semei C, Mukasa B, Musoke W, Vermund S, Dworkin S, Dovidio J, Taylor B, Kershaw T. Protocol for the pilot quasi-experimental controlled trial of a gender-responsive implementation strategy with providers to improve HIV outcomes in Uganda. Pilot And Feasibility Studies 2022, 8: 264. PMID: 36564795, PMCID: PMC9783690, DOI: 10.1186/s40814-022-01202-0.Peer-Reviewed Original ResearchHIV care engagementHIV outcomesCare engagementViral load suppressionPilot intervention trialPatient-provider relationshipEffective clinical interventionsPreliminary evidenceEvidence-based strategiesHIV providersHIV counselingHIV disparitiesHIV treatmentIntervention trialsControl clinicsImplementation strategiesProvider outcomesClinical interventionsProvider capacityTrialsGender-responsive treatmentInterventionOutcomesPatientsTreatment
2020
Integrating and Interpreting Findings from the Latest Treatment as Prevention Trials
Brault MA, Spiegelman D, Abdool Karim SS, Vermund SH. Integrating and Interpreting Findings from the Latest Treatment as Prevention Trials. Current HIV/AIDS Reports 2020, 17: 249-258. PMID: 32297219, PMCID: PMC7260110, DOI: 10.1007/s11904-020-00492-4.Peer-Reviewed Original Research
2019
Treatment as Prevention: Concepts and Challenges for Reducing HIV Incidence
Brault MA, Spiegelman D, Hargreaves J, Nash D, Vermund SH. Treatment as Prevention: Concepts and Challenges for Reducing HIV Incidence. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2019, 82: s104-s112. PMID: 31658196, PMCID: PMC6820703, DOI: 10.1097/qai.0000000000002168.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyHIV transmissionHIV plasma loadReducing HIV IncidenceHIV prevention trialsCommunity-level interventionsDeployable vaccineViral suppressionHIV testingHIV incidencePrevention trialsUninfected personsChronic conditionsHIV investmentsEarly treatmentTreat strategySexual partnersViral expressionTransmission riskHIVTrialsTreatmentInconsistent findingsPreventionSaharan AfricaFrom surviving to thriving: the role of resilience in meeting global HIV goals.
Harrison SE, Li X, Vermund SH. From surviving to thriving: the role of resilience in meeting global HIV goals. AIDS 2019, 33 Suppl 1: s1-s4. PMID: 31397717, PMCID: PMC7024581, DOI: 10.1097/qad.0000000000002242.Peer-Reviewed Original ResearchConceptsResilience-based interventionsRole of resiliencePositive adaptationHealth-related domainsCurrent conceptualizationsHIV care continuumPsychosocial aspectsPublic health strategiesVulnerable individualsHIV populationHIV treatmentCare continuumResilienceHealth strategiesHIVPeopleScientific studiesTreatmentGlobal targetsConceptualizationGlobal fightPopulationIndividualsInterventionAttention
2018
Shifting the HIV Paradigm from Care to Cure: Proceedings from the Caribbean Expert Summit in Barbados, August 2017
Landis R, Abayomi E, Bain B, Greene E, Janossy G, Joseph P, Kerrigan D, McCoy JP, Nunez C, O'Gorman M, Pastoors A, Parekh B, Quimby K, Quinn TC, Robertson K, Thomas R, van Gorp E, Vermund SH, Wilson V. Shifting the HIV Paradigm from Care to Cure: Proceedings from the Caribbean Expert Summit in Barbados, August 2017. AIDS Research And Human Retroviruses 2018, 34: 561-569. PMID: 29732897, PMCID: PMC6053839, DOI: 10.1089/aid.2017.0310.Peer-Reviewed Original ResearchConceptsJoint United Nations ProgrammePublic health benefitsHIV/AIDSPublic health messagingNew medical treatmentsAntiretroviral therapyHIV diseaseUNAIDS 90United Nations ProgrammeMedical treatmentHealth messagingHealth benefitsNations ProgrammeDiseaseInternational expertsCareHealthcare professionsCritical appraisalTreatmentPersistent fearSpirit of optimismStigmaHIVTherapyCommunity level
2017
Adolescents, young people, and the 90–90–90 goals
Wong VJ, Murray KR, Phelps BR, Vermund SH, McCarraher DR. Adolescents, young people, and the 90–90–90 goals. AIDS 2017, 31: s191-s194. PMID: 28665876, PMCID: PMC5497776, DOI: 10.1097/qad.0000000000001539.Peer-Reviewed Original ResearchConceptsHIV testingTreatment initiationJoint United Nations ProgrammeYoung people ages 15People ages 15AIDS 90HIV diagnosisUnited Nations ProgrammePrimary preventionEarly diagnosisHIVNew infectionsAge 15Nations ProgrammeDiagnosisEpidemic controlAdolescentsProgram plannersCurrent low ratesLower ratesYoung peopleNumber of youthRecent studiesTreatmentInitiationExpanded antiretroviral treatment, sexual networks, and condom use: Treatment as prevention unlikely to succeed without partner reduction among men who have sex with men in China
Lou J, Hu P, Qian HZ, Ruan Y, Jin Z, Xing H, Shao Y, Vermund SH. Expanded antiretroviral treatment, sexual networks, and condom use: Treatment as prevention unlikely to succeed without partner reduction among men who have sex with men in China. PLOS ONE 2017, 12: e0171295. PMID: 28406992, PMCID: PMC5390964, DOI: 10.1371/journal.pone.0171295.Peer-Reviewed Original ResearchConceptsCondom use increasesNew HIV infectionsMale sexual partnersPartner reductionCondom useSexual partnersHIV infectionBeijing MSMHIV new infectionsSexual behavioral changesAntiretroviral treatmentHIV testingHIV incidenceHIV prevalenceCombination interventionsSubstantial additional benefitNew infectionsUse increasesSexual networksInfectionMSMMenRisk reductionBehavioral changesTreatment
2014
Mobile clinics for antiretroviral therapy in rural Mozambique
Moon TD, Jequicene T, Blevins M, José E, Lankford JR, Wester CW, Fuchs MC, Vermund SH. Mobile clinics for antiretroviral therapy in rural Mozambique. Bulletin Of The World Health Organization 2014, 92: 680-684. PMID: 25378759, PMCID: PMC4208568, DOI: 10.2471/blt.13.129478.Peer-Reviewed Original ResearchConceptsHIV careClinic strategyHealth care infrastructureAntiretroviral therapy programsHuman immunodeficiency virusUptake of servicesPresident's Emergency PlanLocal health systemsMonths of implementationAntiretroviral therapyImmunodeficiency virusPeripheral clinicsNew patientsMobile clinicsAdult populationART expansionClinicTherapy programAIDS ReliefHealth systemCareTreatmentRural MozambiqueRural regionsNational coveragePediatric Malignancies, Treatment Outcomes and Abandonment of Pediatric Cancer Treatment in Zambia
Slone JS, Chunda-Liyoka C, Perez M, Mutalima N, Newton R, Chintu C, Kankasa C, Chipeta J, Heimburger DC, Vermund SH, Friedman DL. Pediatric Malignancies, Treatment Outcomes and Abandonment of Pediatric Cancer Treatment in Zambia. PLOS ONE 2014, 9: e89102. PMID: 24586527, PMCID: PMC3931678, DOI: 10.1371/journal.pone.0089102.Peer-Reviewed Original ResearchConceptsUniversity Teaching HospitalPediatric oncology wardOncology wardTreatment abandonmentRisk factorsTreatment outcomesRetrospective cohort studyAbandonment of treatmentMode of diagnosisCohort of childrenClinical medical recordsStudy time periodCohort studyOncologic treatmentTreatment regimenMultivariable analysisMedical recordsTeaching hospitalInclusion criteriaLower riskCancerChildrenTreatmentWardsDiagnosis
2010
Effect of treating co-infections on HIV-1 viral load: a systematic review
Modjarrad K, Vermund SH. Effect of treating co-infections on HIV-1 viral load: a systematic review. The Lancet Infectious Diseases 2010, 10: 455-463. PMID: 20610327, PMCID: PMC3071714, DOI: 10.1016/s1473-3099(10)70093-1.Peer-Reviewed Original ResearchConceptsViral load differencesViral loadPlasma HIV-1 RNA concentrationSystematic reviewMean plasma viral loadPlasma HIV RNA concentrationHIV-1 RNA concentrationsHIV-1 viral loadHIV RNA concentrationPlasma viral loadHIV transmission riskViral load reductionNon-pathogenic infectionsCo-infecting pathogensSyphilis treatmentHIV progressionTuberculosis treatmentEligible studiesPopulation-level benefitsTransmission riskLow-income countriesHIVTreatmentInfectionReview
2007
The Future of HIV Prevention: Control of Sexually Transmitted Infections and Circumcision Interventions
Sahasrabuddhe VV, Vermund SH. The Future of HIV Prevention: Control of Sexually Transmitted Infections and Circumcision Interventions. Infectious Disease Clinics Of North America 2007, 21: 241-257. PMID: 17502238, PMCID: PMC2700301, DOI: 10.1016/j.idc.2007.03.005.Peer-Reviewed Original ResearchConceptsHIV infectionGenital tract inflammationMale circumcision programsSTI treatmentCircumcision programsSymptomatic personsHIV preventionCurrent evidenceMale circumcisionCircumcision interventionsInfectionHIVSeparate trialsPreventionTreatmentResearch prioritiesInflammationPersonsControlTrialsCircumcision
2002
Protease Inhibitor Combination Therapy and Decreased Condom Use Among Gay Men
DiCLEMENTE RJ, FUNKHOUSER E, WINGOOD G, FAWAL H, HOLMBERG SD, VERMUND SH. Protease Inhibitor Combination Therapy and Decreased Condom Use Among Gay Men. Southern Medical Journal 2002, 95: 421-425. PMID: 11958240, DOI: 10.1097/00007611-200204000-00009.Peer-Reviewed Original ResearchConceptsProtease inhibitorsProtease inhibitor combination therapyActive heterosexual menHIV-infected personsHigh-risk sexual behaviorRisk reduction counselingInhibitor combination therapyAssociation of treatmentSexual behaviorUnprotected sexual behaviorHigh-risk practicesMedication useCombination therapyPotential confoundersPublic clinicsHealth statusCondom useCurrent sexual practicesMenTreatmentSexual practicesHeterosexual menInhibitorsAlabama communitiesCondomsProtease Inhibitor Combination Therapy and Decreased Condom Use Among Gay Men
DICLEMENTE R, FUNKHOUSER E, WINGOOD G, FAWAL H, HOLMBERG S, VERMUND S. Protease Inhibitor Combination Therapy and Decreased Condom Use Among Gay Men. Southern Medical Journal 2002, 95: 421-425. DOI: 10.1097/00007611-200295040-00010.Peer-Reviewed Original ResearchProtease inhibitorsProtease inhibitor combination therapyActive heterosexual menHIV-infected personsHigh-risk sexual behaviorRisk reduction counselingInhibitor combination therapyAssociation of treatmentSexual behaviorUnprotected sexual behaviorHigh-risk practicesMedication useCombination therapyPotential confoundersPublic clinicsHealth statusCondom useCurrent sexual practicesMenTreatmentSexual practicesHeterosexual menInhibitorsAlabama communitiesCondoms
2001
Opportunities to Improve Prevention and Services for HIV-Infected Women in Nonurban Alabama and Mississippi.
Moon TD, Vermund SH, Tong TC, Holmberg SD. Opportunities to Improve Prevention and Services for HIV-Infected Women in Nonurban Alabama and Mississippi. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2001, 28: 279. PMID: 11694837, DOI: 10.1097/00042560-200111010-00013.Peer-Reviewed Original ResearchConceptsHIV testing sitesHIV treatment sitesTreatment of HIVContinued sexual activityDrug treatment facilitiesAfrican American womenHIV clinicHIV infectionHIV treatmentHIV preventionUnmet needDrug usersHIVWomenSexual activityPreventionTreatment sitesTreatmentMonthsTesting sitesClinicInfectionDiseaseMedicaidOpportunities to Improve Prevention and Services for HIV-Infected Women in Nonurban Alabama and Mississippi
Moon T, Vermund S, Tong T, Holmberg S. Opportunities to Improve Prevention and Services for HIV-Infected Women in Nonurban Alabama and Mississippi. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2001, 28: 279-281. DOI: 10.1097/00126334-200111010-00013.Peer-Reviewed Original ResearchHIV testing sitesHIV treatment sitesTreatment of HIVContinued sexual activityDrug treatment facilitiesAfrican American womenHIV clinicHIV infectionHIV treatmentHIV preventionUnmet needDrug usersHIVWomenSexual activityPreventionTreatment sitesTreatmentMonthsTesting sitesClinicInfectionDiseaseMedicaid
1993
Chlamydial cervical infection in jailed women.
Holmes MD, Safyer SM, Bickell NA, Vermund SH, Hanff PA, Phillips RS. Chlamydial cervical infection in jailed women. American Journal Of Public Health 1993, 83: 551-5. PMID: 8460733, PMCID: PMC1694480, DOI: 10.2105/ajph.83.4.551.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalysis of VarianceChlamydia InfectionsChlamydia trachomatisComorbidityCondomsEducational StatusFemaleHealth PolicyHumansInterviews as TopicMarital StatusMass ScreeningMultivariate AnalysisNew York CityPrevalencePrisonersRacial GroupsRisk FactorsSensitivity and SpecificityUterine Cervical DiseasesVaginal SmearsConceptsChlamydial infectionCervical infectionInfected womenC trachomatisRisk factorsChlamydia trachomatis cervical infectionChlamydial cervical infectionMucopurulent cervical dischargeIndependent risk factorC trachomatis infectionNew York City jailsPelvic tendernessCervical dischargePresumptive treatmentCervical culturesTrachomatis infectionPresumptive therapyPositive culturesAdult womenInfectionWomenPrevalenceTrachomatisCity jailsTreatment