2023
Antihypertensives in Pregnancy
Denoble A, Goldstein S, Pettker C. Antihypertensives in Pregnancy. Obstetrics And Gynecology Clinics Of North America 2023, 50: 39-78. PMID: 36822710, DOI: 10.1016/j.ogc.2022.10.008.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSignificant maternal morbidityTreatment of hypertensionAmniotic fluid volumeHypertensive disordersMaternal morbidityPregnant patientsFetal growthCurrent guidelinesEfficacy dataAvailable safetyPregnancyAntihypertensivesFluid volumeClose supervisionHypertensionMorbidityPatientsPostpartumMortalityAvailable dataDiagnosis
2022
Prospective Observational Study of N-terminal Pro–Brain Natriuretic Peptide Levels in Obese and Nonobese Women during Pregnancy
Denoble A, Moyett J, Goldstein S, Ward CC, Truong T, Erkanli A, James A, Grotegut C. Prospective Observational Study of N-terminal Pro–Brain Natriuretic Peptide Levels in Obese and Nonobese Women during Pregnancy. American Journal Of Perinatology 2022, 40: 467-474. PMID: 35973801, PMCID: PMC10168705, DOI: 10.1055/a-1925-1532.Peer-Reviewed Original ResearchConceptsNT-proBNP levelsBody mass indexProspective observational studyObese patientsNonobese patientsNT-proBNPWeeks postpartumObservational studyN-terminal pro-brain natriuretic peptide levelsN-terminal pro-brain natriuretic peptidePro-brain natriuretic peptide levelsLinear mixed effects modelsLower NT-proBNP levelsHigher systolic blood pressurePro-brain natriuretic peptidePregnant peopleNatriuretic peptide levelsSignificant medical comorbiditiesTime pointsSystolic blood pressureMixed effects modelsEffects modelLogNT-proBNPPP elevationHypertensive disordersRisk Factors and Outcomes Associated With Hypertensive Disorders of Pregnancy in Maternal Congenital Heart Disease
Goldstein S, Savu A, Islam S, Ward C, Krasuski R, Grotegut C, Newby L, Hornberger L, Windram J, Kaul P. Risk Factors and Outcomes Associated With Hypertensive Disorders of Pregnancy in Maternal Congenital Heart Disease. JACC Advances 2022, 1: 100036. PMID: 38939317, PMCID: PMC11198567, DOI: 10.1016/j.jacadv.2022.100036.Peer-Reviewed Original ResearchCongenital heart diseaseAssociation of HDPRisk factorsAdverse eventsAdverse outcomesCongenital heart disease lesionsHypertensive disorders of pregnancyPresence of HDPGestational age infantsDisorders of pregnancyAssociated with HDPPrevalence of HDPAssociated with increased riskRetrospective cohort studyDisease backgroundAssociated with certain adverse outcomesDelivery admissionPreterm deliveryHypertensive disordersChronic hypertensionAge infantsLive birthsMaternal characteristicsDiabetes mellitusStrength of association