Featured Publications
Latent Transition Analysis of the Symptom Experience of Cancer Patients Undergoing Chemotherapy
Jeon S, Sikorskii A, Given BA, Given CW, Redeker NS. Latent Transition Analysis of the Symptom Experience of Cancer Patients Undergoing Chemotherapy. Nursing Research 2019, 68: 91-98. PMID: 30540701, PMCID: PMC6399048, DOI: 10.1097/nnr.0000000000000332.Peer-Reviewed Original ResearchConceptsSymptom experienceCancer patientsYoung adultsEmotional role functioningTreatment-related symptomsClass A patientsBetter physical functionAdult cancer patientsGeneral health perceptionRandomized clinical trialsClustering of symptomsPatients' symptom experiencesSymptom management interventionsLatent transition analysisNumber of symptomsQuality of lifeLess comorbidityA patientsSymptom managementPhysical functionClinical trialsHealth perceptionMultiple symptomsRole functioningPatients' membership
2024
Association between adverse childhood experiences and self-reported health-risk behaviors among cancer survivors: A population-based study
Sarkar S, Jackson B, Manzo L, Jeon S, Poghosyan H. Association between adverse childhood experiences and self-reported health-risk behaviors among cancer survivors: A population-based study. PLOS ONE 2024, 19: e0299918. PMID: 38512934, PMCID: PMC10956880, DOI: 10.1371/journal.pone.0299918.Peer-Reviewed Original ResearchConceptsHealth risk behaviorsSelf-reported health risk behaviorsAdverse childhood experiencesHistory of adverse childhood experiencesOdds of reportingCancer survivorsE-cigarette useIncreased odds of reportingReport adverse childhood experiencesPrevalence of adverse childhood experiencesSelf-reportAlcohol drinkingHigher odds of reportingAdult cancer survivorsE-cigarettesSurvivor self-reportPrevent health risk behaviorsAdverse childhood experience historyChildhood experiencesAssociated with health risk behaviorsCigarette smokingHistory of cancerPopulation-based studyPrimary independent variableMultivariate logistic regression
2022
Association between social connectedness and stress or anxiety among older cancer survivors during the 2020–2021 winter surge of the COVID-19 pandemic
Poghosyan H, Margaryan Y, Jeon S, Edelman EJ, Yu JB. Association between social connectedness and stress or anxiety among older cancer survivors during the 2020–2021 winter surge of the COVID-19 pandemic. Journal Of Geriatric Oncology 2022, 14: 101390. PMID: 36274031, PMCID: PMC9554341, DOI: 10.1016/j.jgo.2022.10.005.Peer-Reviewed Original ResearchRacial and Ethnic Variation in COVID-19 Vaccination Uptake Among Medicare Beneficiaries with Cancer History
Poghosyan H, Dinan MA, Tamamyan G, Nelson L, Jeon S. Racial and Ethnic Variation in COVID-19 Vaccination Uptake Among Medicare Beneficiaries with Cancer History. Journal Of Racial And Ethnic Health Disparities 2022, 10: 2354-2362. PMID: 36149576, PMCID: PMC9510246, DOI: 10.1007/s40615-022-01415-2.Peer-Reviewed Original ResearchConceptsNon-Hispanic white beneficiariesCancer historyVaccine doseMedicare beneficiariesWhite beneficiariesVaccine uptakeHispanic beneficiariesMultivariable logistic regression analysisCOVID-19 vaccination uptakeSelf-reported cancer historyCOVID-19 vaccine uptakeSelf-reported receiptCOVID-19 vaccination ratesLogistic regression analysisNon-Hispanic blacksSelf-reported raceUnvaccinated beneficiariesVaccination uptakeVaccine dosesVaccination ratesVaccine confidenceVaccine availabilitySupplement surveyCross-sectional dataEthnic variation
2020
The role of the gut microbiome in cancer-related fatigue: pilot study on epigenetic mechanisms
Xiao C, Fedirko V, Beitler J, Bai J, Peng G, Zhou C, Gu J, Zhao H, Lin IH, Chico CE, Jeon S, Knobf TM, Conneely KN, Higgins K, Shin DM, Saba N, Miller A, Bruner D. The role of the gut microbiome in cancer-related fatigue: pilot study on epigenetic mechanisms. Supportive Care In Cancer 2020, 29: 3173-3182. PMID: 33078326, PMCID: PMC8055716, DOI: 10.1007/s00520-020-05820-3.Peer-Reviewed Original ResearchConceptsCancer-related fatigueGut microbiomePilot studyHigh-fatigue groupLow-fatigue groupsGut-brain axisMultidimensional Fatigue InventoryGut microbiota patternBrain healthCancer patientsFatigue InventoryNeck cancerPurposeRecent evidenceStool samplesImmune responseMicrobiota patternsGut microbiotaInflammationOne monthBrain functionPatientsConclusionsOur resultsFatty acid synthesisEPIC BeadChipDNA methylation changes
2017
The Yale Fitness Intervention Trial in female cancer survivors: Cardiovascular and physiological outcomes
Knobf MT, Jeon S, Smith B, Harris L, Thompson S, Stacy MR, Insogna K, Sinusas AJ. The Yale Fitness Intervention Trial in female cancer survivors: Cardiovascular and physiological outcomes. Heart & Lung 2017, 46: 375-381. PMID: 28803675, PMCID: PMC6129386, DOI: 10.1016/j.hrtlng.2017.06.001.Peer-Reviewed Original ResearchConceptsFemale cancer survivorsCancer survivorsCenter interventionMET-minutes/weekStable insulin levelsMetabolic risk factorsResistance exercise programExercise stress testCardiovascular disease riskPhysical activity groupImproved insulin resistanceHeart rate recoveryMinutes/weekRisk reduction interventionsMajority of subjectsAdjuvant chemotherapyPremature menopauseExercise programInsulin levelsInsulin resistanceIntervention trialsRisk factorsCardiovascular functionBreast cancerRate recoveryOptimism, Symptom Distress, Illness Appraisal, and Coping in Patients With Advanced-Stage Cancer Diagnoses Undergoing Chemotherapy Treatment.
Sumpio C, Jeon S, Northouse LL, Knobf MT. Optimism, Symptom Distress, Illness Appraisal, and Coping in Patients With Advanced-Stage Cancer Diagnoses Undergoing Chemotherapy Treatment. Oncology Nursing Forum 2017, 44: 384-392. PMID: 28635986, DOI: 10.1188/17.onf.384-392.Peer-Reviewed Original ResearchConceptsSymptom distressMood disturbanceIllness appraisalsAdvanced-stage cancer diagnosisTreatment complexityComprehensive nursing assessmentSmilow Cancer HospitalYale-New HavenMedical record reviewAdvanced-stage cancerComprehensive cancer centerGreater symptom distressCross-sectional studyGreater mood disturbanceAdult patientsActive chemotherapyRecord reviewCancer HospitalNursing assessmentCancer CenterChemotherapy treatmentIndirect effectsSelf-report questionnairesStage IIIPatients
2016
Exploring the individual patterns of spiritual well-being in people newly diagnosed with advanced cancer: a cluster analysis
Bai M, Dixon J, Williams AL, Jeon S, Lazenby M, McCorkle R. Exploring the individual patterns of spiritual well-being in people newly diagnosed with advanced cancer: a cluster analysis. Quality Of Life Research 2016, 25: 2765-2773. PMID: 27271809, DOI: 10.1007/s11136-016-1328-0.Peer-Reviewed Original ResearchMeSH KeywordsCluster AnalysisFemaleHumansMaleMiddle AgedNeoplasmsQuality of LifeSpiritualitySurvivors
2015
An Advanced Practice Nurse Coordinated Multidisciplinary Intervention for Patients with Late-Stage Cancer: A Cluster Randomized Trial
McCorkle R, Jeon S, Ercolano E, Lazenby M, Reid A, Davies M, Viveiros D, Gettinger S. An Advanced Practice Nurse Coordinated Multidisciplinary Intervention for Patients with Late-Stage Cancer: A Cluster Randomized Trial. Journal Of Palliative Medicine 2015, 18: 962-969. PMID: 26305992, PMCID: PMC4638201, DOI: 10.1089/jpm.2015.0113.Peer-Reviewed Original ResearchConceptsLate-stage cancerSelf-reported clinical outcomesSecondary outcomesPalliative carePatient outcomesMonths postbaselinePrimary patient-reported outcomesEarly palliative careComprehensive cancer carePatient-reported outcomesAdvanced practice nursesWhole patient careLinear mixed model analysisUsual carePrimary outcomeClinical outcomesMultidisciplinary clinicPractice nursesCancer careClinic levelMultidisciplinary interventionTrial designMixed model analysisGeneral linear mixed model analysisTranslational studiesTreatment complexity: a description of chemotherapy and supportive care treatment visits in patients with advanced-stage cancer diagnoses
Sumpio C, Knobf MT, Jeon S. Treatment complexity: a description of chemotherapy and supportive care treatment visits in patients with advanced-stage cancer diagnoses. Supportive Care In Cancer 2015, 24: 285-293. PMID: 26026977, DOI: 10.1007/s00520-015-2775-9.Peer-Reviewed Original ResearchConceptsSC visitsVisit typeYoung subjectsTotal visitsAdvanced-stage cancer diagnosisTreatment complexityMethodsElectronic medical recordsTerms of chemotherapyAdvanced-stage patientsMore hoursMore total visitsChemotherapy visitsLung subjectsChemotherapy regimensCare visitsOlder patientsSupportive careYounger patientsTreatment visitsOutpatient infusionsCancer patientsMedical recordsTreatment periodAdditional visitsStage III
2014
Exploring the relationship between spiritual well-being and quality of life among patients newly diagnosed with advanced cancer
Bai M, Lazenby M, Jeon S, Dixon J, McCorkle R. Exploring the relationship between spiritual well-being and quality of life among patients newly diagnosed with advanced cancer. Palliative & Supportive Care 2014, 13: 927-935. PMID: 24992001, DOI: 10.1017/s1478951514000820.Peer-Reviewed Original ResearchConceptsQuality of lifeAdvanced cancerFunctional assessmentChronic Illness Therapy-Spiritual WellCancer Therapy-GeneralFACIT-Sp-12Advanced cancer experienceClinical trialsSecondary data analysisCancer experiencePatientsQoLCancerStage 3DiagnosisLongitudinal studyMonthsSpiritual wellControl conditionFuture studiesDaysLong periodAssociationQoL.SPWB
2012
A nonparametric test for equality of survival medians
Rahbar MH, Chen Z, Jeon S, Gardiner JC, Ning J. A nonparametric test for equality of survival medians. Statistics In Medicine 2012, 31: 844-854. PMID: 22302559, PMCID: PMC4005606, DOI: 10.1002/sim.5309.Peer-Reviewed Original Research
2010
Deconstruction of Nurse-Delivered Patient Self-Management Interventions for Symptom Management: Factors Related to Delivery Enactment and Response
Given CW, Given BA, Sikorskii A, You M, Jeon S, Champion V, McCorkle R. Deconstruction of Nurse-Delivered Patient Self-Management Interventions for Symptom Management: Factors Related to Delivery Enactment and Response. Annals Of Behavioral Medicine 2010, 40: 99-113. PMID: 20544405, PMCID: PMC2928661, DOI: 10.1007/s12160-010-9191-7.Peer-Reviewed Original ResearchConceptsSelf-management interventionsSymptom responseRandomized clinical trialsClustering of symptomsSymptom managementCancer patientsClinical trialsSymptom characteristicsPatientsSymptomsSymptom factorsNurses' decisionsSix-contactNursesLonger durationIntervention strategiesPatient enactmentInterventionResponseNumber of strategiesTrials
2009
The Utility of Screening in the Design of Trials for Symptom Management in Cancer
Jeon S, Given CW, Sikorskii A, Given B. The Utility of Screening in the Design of Trials for Symptom Management in Cancer. Journal Of Pain And Symptom Management 2009, 38: 606-614. PMID: 19699052, PMCID: PMC2761530, DOI: 10.1016/j.jpainsymman.2009.02.233.Peer-Reviewed Original ResearchConceptsSymptom managementIntervention contactsSeverity scoreClinical trialsCancer symptom management trialsLikelihood ratioUtility of screeningSeverity of symptomsDesign of trialsSymptom management trialsPost-test probabilityReceipt of interventionTrial entryCancer patientsPatientsTrial designSymptomsDiscriminative accuracyRating ScaleTrialsSeverityCharacteristic curveManagement trialsCancerInterventionDifferential Symptom Reporting by Mode of Administration of the Assessment
Sikorskii A, Given CW, Given B, Jeon S, You M. Differential Symptom Reporting by Mode of Administration of the Assessment. Medical Care 2009, 47: 866-874. PMID: 19584761, PMCID: PMC2722377, DOI: 10.1097/mlr.0b013e3181a31d00.Peer-Reviewed Original ResearchConceptsNurse armSymptom managementMode of administrationIntervention contactsSymptom reportingTelephone interviewsPatient-reported outcome dataCancer-related symptomsSymptom management strategiesSymptom management interventionsHigher severityPoor appetitePatient reportingCancer patientsSymptom assessmentClinical trialsSymptom monitoringOutcome dataPatientsClinical practiceSolid tumorsVoice response systemOlder groupSymptomsIntake interviewResponse analysis for multiple symptoms revealed differences between arms of a symptom management trial
Sikorskii A, Given CW, You M, Jeon S, Given BA. Response analysis for multiple symptoms revealed differences between arms of a symptom management trial. Journal Of Clinical Epidemiology 2009, 62: 716-724. PMID: 19124223, PMCID: PMC2743381, DOI: 10.1016/j.jclinepi.2008.09.007.Peer-Reviewed Original ResearchConceptsSymptom management trialsIntervention contactsMultiple symptomsCancer-related symptomsProportional hazards modelManagement trialsScore of severityCancer painClinical improvementPoor appetiteSymptom managementCognitive-behavioral interventionsDisease characteristicsCancer patientsHazards modelPatientsSymptomsStudy designTrialsSeverityGood responseMarginal proportional hazards modelInterventionArmResponse
2008
Do Interference-Based Cut-Points Differentiate Mild, Moderate, and Severe Levels of 16 Cancer-Related Symptoms Over Time?
Jeon S, Given CW, Sikorskii A, Given B. Do Interference-Based Cut-Points Differentiate Mild, Moderate, and Severe Levels of 16 Cancer-Related Symptoms Over Time? Journal Of Pain And Symptom Management 2008, 37: 220-232. PMID: 18619769, PMCID: PMC2746058, DOI: 10.1016/j.jpainsymman.2008.01.010.Peer-Reviewed Original ResearchActivities of Daily LivingAdultAgedAged, 80 and overDiagnosis, DifferentialDisability EvaluationFemaleHumansMaleMiddle AgedNeoplasmsPainPain MeasurementQuality of LifeRandomized Controlled Trials as TopicReproducibility of ResultsSensitivity and SpecificitySeverity of Illness IndexSickness Impact Profile
2007
Establishing Mild, Moderate, and Severe Scores for Cancer-Related Symptoms: How Consistent and Clinically Meaningful Are Interference-Based Severity Cut-Points?
Given B, Given CW, Sikorskii A, Jeon S, McCorkle R, Champion V, Decker D. Establishing Mild, Moderate, and Severe Scores for Cancer-Related Symptoms: How Consistent and Clinically Meaningful Are Interference-Based Severity Cut-Points? Journal Of Pain And Symptom Management 2007, 35: 126-135. PMID: 18158231, PMCID: PMC2635012, DOI: 10.1016/j.jpainsymman.2007.03.012.Peer-Reviewed Original ResearchSymptom Management for Cancer Patients: A Trial Comparing Two Multimodal Interventions
Sikorskii A, Given CW, Given B, Jeon S, Decker V, Decker D, Champion V, McCorkle R. Symptom Management for Cancer Patients: A Trial Comparing Two Multimodal Interventions. Journal Of Pain And Symptom Management 2007, 34: 253-264. PMID: 17618080, PMCID: PMC2043403, DOI: 10.1016/j.jpainsymman.2006.11.018.Peer-Reviewed Original ResearchConceptsLung cancer patientsCancer patientsSymptom managementIntervention contactsSymptom severityNon-lung cancer patientsSeverity of symptomsGreater symptom severitySignificant reductionConventional careSevere symptomsMultimodal interventionPatientsSymptom patternsSolid tumorsEight-weekPrior trialsPostintervention observationSeveritySymptomsInteractive interventionChemotherapyInterventionLongitudinal analysisBaselineThe influence of end‐of‐life cancer care on caregivers
Doorenbos AZ, Given B, Given CW, Wyatt G, Gift A, Rahbar M, Jeon S. The influence of end‐of‐life cancer care on caregivers. Research In Nursing & Health 2007, 30: 270-281. PMID: 17514724, DOI: 10.1002/nur.20217.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAdaptation, PsychologicalAge FactorsAgedAttitude to HealthCaregiversCost of IllnessDepressionEmploymentFamilyFemaleHome NursingHumansLinear ModelsMaleMichiganMiddle AgedModels, PsychologicalNeoplasmsNursing Methodology ResearchProspective StudiesSurveys and QuestionnairesSurvivorsTerminal CareConceptsCaregiver depressive symptomatologySurvival statusDepressive symptomatologyLife cancer careCaregiver health statusNon-spousal caregiversFamily members' symptomsFamily membersCancer careProspective dataDaily livingSpousal caregiversHealth statusSecondary analysisGreater burdenElderly family membersCaregiversSymptomatologyBurdenStatusSymptomsCancerCare