Featured Publications
Polysomnographic phenotypes and their cardiovascular implications in obstructive sleep apnoea
Zinchuk AV, Jeon S, Koo BB, Yan X, Bravata DM, Qin L, Selim BJ, Strohl KP, Redeker NS, Concato J, Yaggi HK. Polysomnographic phenotypes and their cardiovascular implications in obstructive sleep apnoea. Thorax 2017, 73: 472. PMID: 28935698, PMCID: PMC6693344, DOI: 10.1136/thoraxjnl-2017-210431.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedCardiovascular DiseasesCluster AnalysisCross-Sectional StudiesFemaleHumansIschemic Attack, TransientLongitudinal StudiesMaleMiddle AgedMortalityPhenotypePolysomnographyProportional Hazards ModelsRisk AssessmentSeverity of Illness IndexSleep Apnea, ObstructiveStrokeConceptsObstructive sleep apnoeaCardiovascular outcomesPolysomnographic featuresSleep apnoeaPolysomnographic dataIncident transient ischemic attackUS Veteran cohortTransient ischemic attackAcute coronary syndromeAdverse cardiovascular outcomesPeriodic limb movementsOSA severity classificationPolysomnographic phenotypeCoronary syndromeIschemic attackCardiovascular implicationsOSA phenotypesOSA evaluationPathophysiological domainsPoor sleepMild/Patient clustersVeteran cohortSurvival analysisCombined outcomeSleep Disturbance, Daytime Symptoms, and Functional Performance in Patients With Stable Heart Failure
Jeon S, Redeker NS. Sleep Disturbance, Daytime Symptoms, and Functional Performance in Patients With Stable Heart Failure. Nursing Research 2016, 65: 259-267. PMID: 27362512, PMCID: PMC4930009, DOI: 10.1097/nnr.0000000000000169.Peer-Reviewed Original ResearchConceptsSelf-reported functional performanceStable heart failureDaytime symptomsHeart failureSleep disturbancesNew York Heart Association class ISix-minute walk testFunctional performanceRespiratory disturbance indexPoorer functional performanceHF patientsSymptom burdenWalk testRespiratory indexObservational studySleep qualityInsomnia symptomsAmbulatory polysomnographyPatientsSecondary analysisSymptomsClass IDisturbance indexExploratory regression analysisRegression analysisDetecting a clinically meaningful change in tic severity in Tourette syndrome: A comparison of three methods
Jeon S, Walkup JT, Woods DW, Peterson A, Piacentini J, Wilhelm S, Katsovich L, McGuire JF, Dziura J, Scahill L. Detecting a clinically meaningful change in tic severity in Tourette syndrome: A comparison of three methods. Contemporary Clinical Trials 2013, 36: 414-420. PMID: 24001701, PMCID: PMC3999642, DOI: 10.1016/j.cct.2013.08.012.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBehavior TherapyChildHumansMaleMiddle AgedSeverity of Illness IndexTicsTourette SyndromeTreatment OutcomeYoung AdultConceptsOdds ratioTourette syndromeYGTSS total tic scoreChronic tic disorderPositive treatment responsePositive responseTic scoreTic disordersTreatment responseTic severityTreatment assignmentBehavioral treatmentSignal detection analysisBehavioral interventionsSyndromeCGICategorical measuresTrialsMeaningful changeSeverityPercent reductionOptimal sensitivityDimensional measuresResponse
2021
A distinct association of inflammatory molecules with outcomes of COVID-19 in younger versus older adults
Shin JJ, Jeon S, Unlu S, Par-Young J, Shin MS, Kuster JK, Afinogenova Y, Kang Y, Simonov M, Buller G, Bucala R, Kang I. A distinct association of inflammatory molecules with outcomes of COVID-19 in younger versus older adults. Clinical Immunology 2021, 232: 108857. PMID: 34560283, PMCID: PMC8455237, DOI: 10.1016/j.clim.2021.108857.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAgingCOVID-19CytokinesFemaleHumansInflammationInflammation MediatorsMaleMiddle AgedRisk FactorsSARS-CoV-2Severity of Illness IndexConceptsClinical outcomesOlder adultsInflammatory moleculesHospitalized adult COVID-19 patientsOlder subjectsAdult COVID-19 patientsSoluble IL-2 receptor alphaIL-2 receptor alphaCOVID-19Different immunologic mechanismsAcute phase reactantsCOVID-19 patientsDevastating clinical outcomesT cell activationImmunologic mechanismsIL-10Immune agingInflammatory processImmune mechanismsPhase reactantsSevere diseaseReceptor alphaCell activationDisease severityBiological predictors
2017
Validation of the ICD-9 Diagnostic Code for Palliative Care in Patients Hospitalized With Heart Failure Within the Veterans Health Administration
Feder SL, Redeker NS, Jeon S, Schulman-Green D, Womack JA, Tate JP, Bedimo RJ, Budoff MJ, Butt AA, Crothers K, Akgün KM. Validation of the ICD-9 Diagnostic Code for Palliative Care in Patients Hospitalized With Heart Failure Within the Veterans Health Administration. American Journal Of Hospice And Palliative Medicine® 2017, 35: 959-965. PMID: 29254358, PMCID: PMC7491538, DOI: 10.1177/1049909117747519.Peer-Reviewed Original ResearchConceptsVeterans Health AdministrationSpecialist palliative carePalliative care consultationHeart failurePalliative careCare consultationsHealth AdministrationElectronic health record reviewICD-9 diagnostic codesIntensive care unit admissionSpecialist palliative care consultationUnmet palliative care needsVeterans Aging Cohort StudyCare unit admissionHealth record reviewPalliative care needsPalliative care servicesAging Cohort StudyGoals of careNinth Revision codesICD-9 codesYear of hospitalizationSite of careNegative predictive valueUnit admissionThe Measurement of Transitions in Cancer Scale
Schulman-Green D, Jeon S, McCorkle R, Dixon J. The Measurement of Transitions in Cancer Scale. Journal Of Nursing Measurement 2017, 25: 103-120. PMID: 28395703, DOI: 10.1891/1061-3749.25.1.103.Peer-Reviewed Original Research
2016
The Association between Nocturnal Cardiac Arrhythmias and Sleep-Disordered Breathing: The DREAM Study.
Selim BJ, Koo BB, Qin L, Jeon S, Won C, Redeker NS, Lampert RJ, Concato JP, Bravata DM, Ferguson J, Strohl K, Bennett A, Zinchuk A, Yaggi HK. The Association between Nocturnal Cardiac Arrhythmias and Sleep-Disordered Breathing: The DREAM Study. Journal Of Clinical Sleep Medicine 2016, 12: 829-37. PMID: 26951420, PMCID: PMC4877315, DOI: 10.5664/jcsm.5880.Peer-Reviewed Original ResearchMeSH KeywordsArrhythmias, CardiacCohort StudiesCross-Sectional StudiesFemaleHumansMaleMiddle AgedPolysomnographyProspective StudiesSeverity of Illness IndexSleep Apnea SyndromesVeteransConceptsSleep-disordered breathingNocturnal cardiac arrhythmiasIntraventricular conduction delayApnea-hypopnea indexCardiac arrhythmiasTwo-fold oddsModerate-severe sleep-disordered breathingSeverity of SDBSevere sleep-disordered breathingComplex ventricular ectopyMultiple cardiovascular comorbiditiesObstructive respiratory eventsClinic-based populationCross-sectional analysisCardiovascular comorbiditiesSDB patientsVentricular ectopySDB severityRespiratory eventsUnadjusted oddsSupraventricular tachycardiaCardiovascular diseaseArrhythmia subtypesArrhythmia riskConduction delay
2010
Deconstruction of Nurse-Delivered Patient Self-Management Interventions for Symptom Management: Factors Related to Delivery Enactment and Response
Given CW, Given BA, Sikorskii A, You M, Jeon S, Champion V, McCorkle R. Deconstruction of Nurse-Delivered Patient Self-Management Interventions for Symptom Management: Factors Related to Delivery Enactment and Response. Annals Of Behavioral Medicine 2010, 40: 99-113. PMID: 20544405, PMCID: PMC2928661, DOI: 10.1007/s12160-010-9191-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultFemaleHumansMaleMiddle AgedNeoplasmsNursing CarePatient Acceptance of Health CareSelf CareSeverity of Illness IndexConceptsSelf-management interventionsSymptom responseRandomized clinical trialsClustering of symptomsSymptom managementCancer patientsClinical trialsSymptom characteristicsPatientsSymptomsSymptom factorsNurses' decisionsSix-contactNursesLonger durationIntervention strategiesPatient enactmentInterventionResponseNumber of strategiesTrials
2009
Differential Symptom Reporting by Mode of Administration of the Assessment
Sikorskii A, Given CW, Given B, Jeon S, You M. Differential Symptom Reporting by Mode of Administration of the Assessment. Medical Care 2009, 47: 866-874. PMID: 19584761, PMCID: PMC2722377, DOI: 10.1097/mlr.0b013e3181a31d00.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedAged, 80 and overAutomationFemaleHumansInterviews as TopicMaleMiddle AgedNeoplasmsNursesSeverity of Illness IndexSex FactorsSocioeconomic FactorsTelephoneConceptsNurse armSymptom managementMode of administrationIntervention contactsSymptom reportingTelephone interviewsPatient-reported outcome dataCancer-related symptomsSymptom management strategiesSymptom management interventionsHigher severityPoor appetitePatient reportingCancer patientsSymptom assessmentClinical trialsSymptom monitoringOutcome dataPatientsClinical practiceSolid tumorsVoice response systemOlder groupSymptomsIntake interviewResponse analysis for multiple symptoms revealed differences between arms of a symptom management trial
Sikorskii A, Given CW, You M, Jeon S, Given BA. Response analysis for multiple symptoms revealed differences between arms of a symptom management trial. Journal Of Clinical Epidemiology 2009, 62: 716-724. PMID: 19124223, PMCID: PMC2743381, DOI: 10.1016/j.jclinepi.2008.09.007.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge DistributionAgedCognitive Behavioral TherapyData Interpretation, StatisticalFemaleHumansMiddle AgedNeoplasmsSeverity of Illness IndexTelephoneTreatment OutcomeConceptsSymptom management trialsIntervention contactsMultiple symptomsCancer-related symptomsProportional hazards modelManagement trialsScore of severityCancer painClinical improvementPoor appetiteSymptom managementCognitive-behavioral interventionsDisease characteristicsCancer patientsHazards modelPatientsSymptomsStudy designTrialsSeverityGood responseMarginal proportional hazards modelInterventionArmResponse
2008
Do Interference-Based Cut-Points Differentiate Mild, Moderate, and Severe Levels of 16 Cancer-Related Symptoms Over Time?
Jeon S, Given CW, Sikorskii A, Given B. Do Interference-Based Cut-Points Differentiate Mild, Moderate, and Severe Levels of 16 Cancer-Related Symptoms Over Time? Journal Of Pain And Symptom Management 2008, 37: 220-232. PMID: 18619769, PMCID: PMC2746058, DOI: 10.1016/j.jpainsymman.2008.01.010.Peer-Reviewed Original ResearchActivities of Daily LivingAdultAgedAged, 80 and overDiagnosis, DifferentialDisability EvaluationFemaleHumansMaleMiddle AgedNeoplasmsPainPain MeasurementQuality of LifeRandomized Controlled Trials as TopicReproducibility of ResultsSensitivity and SpecificitySeverity of Illness IndexSickness Impact Profile
2007
Establishing Mild, Moderate, and Severe Scores for Cancer-Related Symptoms: How Consistent and Clinically Meaningful Are Interference-Based Severity Cut-Points?
Given B, Given CW, Sikorskii A, Jeon S, McCorkle R, Champion V, Decker D. Establishing Mild, Moderate, and Severe Scores for Cancer-Related Symptoms: How Consistent and Clinically Meaningful Are Interference-Based Severity Cut-Points? Journal Of Pain And Symptom Management 2007, 35: 126-135. PMID: 18158231, PMCID: PMC2635012, DOI: 10.1016/j.jpainsymman.2007.03.012.Peer-Reviewed Original ResearchSymptom Management for Cancer Patients: A Trial Comparing Two Multimodal Interventions
Sikorskii A, Given CW, Given B, Jeon S, Decker V, Decker D, Champion V, McCorkle R. Symptom Management for Cancer Patients: A Trial Comparing Two Multimodal Interventions. Journal Of Pain And Symptom Management 2007, 34: 253-264. PMID: 17618080, PMCID: PMC2043403, DOI: 10.1016/j.jpainsymman.2006.11.018.Peer-Reviewed Original ResearchConceptsLung cancer patientsCancer patientsSymptom managementIntervention contactsSymptom severityNon-lung cancer patientsSeverity of symptomsGreater symptom severitySignificant reductionConventional careSevere symptomsMultimodal interventionPatientsSymptom patternsSolid tumorsEight-weekPrior trialsPostintervention observationSeveritySymptomsInteractive interventionChemotherapyInterventionLongitudinal analysisBaseline
2006
Testing the Effects of Treatment Complications on a Cognitive-Behavioral Intervention for Reducing Symptom Severity
Sikorskii A, Given C, Given B, Jeon S, McCorkle R. Testing the Effects of Treatment Complications on a Cognitive-Behavioral Intervention for Reducing Symptom Severity. Journal Of Pain And Symptom Management 2006, 32: 129-139. PMID: 16877180, DOI: 10.1016/j.jpainsymman.2006.02.013.Peer-Reviewed Original ResearchConceptsCognitive-behavioral interventionsSymptom severityConventional careTreatment complicationsComorbid conditionsDose delay/reductionMore comorbid conditionsSymptom Severity IndexDelays/reductionsNeutropenic eventsPatient characteristicsPrimary outcomeExperimental armSeverity scoreClinical conditionsDose reductionSolid tumorsSeveritySeverity IndexInterventionChemotherapyComplicationsPatientsLower severityCare
2004
Effect of a Cognitive Behavioral Intervention on Reducing Symptom Severity During Chemotherapy
Given C, Given B, Rahbar M, Jeon S, McCorkle R, Cimprich B, Galecki A, Kozachik S, Brady A, Fisher-Malloy MJ, Courtney K, Bowie E. Effect of a Cognitive Behavioral Intervention on Reducing Symptom Severity During Chemotherapy. Journal Of Clinical Oncology 2004, 22: 507-516. PMID: 14752074, DOI: 10.1200/jco.2004.01.241.Peer-Reviewed Original ResearchConceptsSupportive care medicationsCognitive-behavioral interventionsSymptom severitySupportive medicationsCare medicationsConventional careBehavioral interventionsExperimental interventionCommunity cancer centerProportion of patientsSymptom Severity IndexBaseline symptom severityStage of cancerHigher symptom severityExperimental groupPrimary outcomeChemotherapy protocolsCancer CenterSeverity scoreMedical recordsTreatment statusPatientsMedicationsSolid tumorsChemotherapy