2021
A distinct association of inflammatory molecules with outcomes of COVID-19 in younger versus older adults
Shin JJ, Jeon S, Unlu S, Par-Young J, Shin MS, Kuster JK, Afinogenova Y, Kang Y, Simonov M, Buller G, Bucala R, Kang I. A distinct association of inflammatory molecules with outcomes of COVID-19 in younger versus older adults. Clinical Immunology 2021, 232: 108857. PMID: 34560283, PMCID: PMC8455237, DOI: 10.1016/j.clim.2021.108857.Peer-Reviewed Original ResearchConceptsClinical outcomesOlder adultsInflammatory moleculesHospitalized adult COVID-19 patientsOlder subjectsAdult COVID-19 patientsSoluble IL-2 receptor alphaIL-2 receptor alphaCOVID-19Different immunologic mechanismsAcute phase reactantsCOVID-19 patientsDevastating clinical outcomesT cell activationImmunologic mechanismsIL-10Immune agingInflammatory processImmune mechanismsPhase reactantsSevere diseaseReceptor alphaCell activationDisease severityBiological predictors
2018
The Association Between HIV Infection and the Use of Palliative Care in Patients Hospitalized With Heart Failure
Feder SL, Tate JP, Akgün KM, Womack JA, Jeon S, Funk M, Bedimo RJ, Budoff MJ, Butt AA, Crothers K, Redeker NS. The Association Between HIV Infection and the Use of Palliative Care in Patients Hospitalized With Heart Failure. American Journal Of Hospice And Palliative Medicine® 2018, 36: 228-234. PMID: 30304939, PMCID: PMC7457998, DOI: 10.1177/1049909118804465.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedCase-Control StudiesCD4 Lymphocyte CountComorbidityFemaleHeart FailureHIV InfectionsHospitalizationHumansLength of StayLogistic ModelsMaleMiddle AgedPalliative CarePatient DischargeRespiration, ArtificialRisk FactorsSex FactorsUnited StatesUnited States Department of Veterans AffairsConceptsHeart failureHIV infectionHIV-1 RNAPalliative careVeterans Health AdministrationHospitalized patientsHIV characteristicsPrimary diagnosisVeterans Aging Cohort StudyPalliative care useVentricular ejection fractionAging Cohort StudyCells/Case-control studyConditional logistic regressionDiseases NinthCohort studyEjection fractionPrimary outcomeVHA patientsDischarge dateMean ageCare useSevere diseaseAdjusted model