2023
An AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model
Charkoftaki G, Aalizadeh R, Santos-Neto A, Tan W, Davidson E, Nikolopoulou V, Wang Y, Thompson B, Furnary T, Chen Y, Wunder E, Coppi A, Schulz W, Iwasaki A, Pierce R, Cruz C, Desir G, Kaminski N, Farhadian S, Veselkov K, Datta R, Campbell M, Thomaidis N, Ko A, Thompson D, Vasiliou V. An AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model. Human Genomics 2023, 17: 80. PMID: 37641126, PMCID: PMC10463861, DOI: 10.1186/s40246-023-00521-4.Peer-Reviewed Original ResearchConceptsCOVID-19 patientsDisease severityViral outbreaksFuture viral outbreaksLength of hospitalizationIntensive care unitWorse disease prognosisLife-threatening illnessEffective medical interventionsCOVID-19Clinical decision treeGlucuronic acid metabolitesNew potential biomarkersHospitalization lengthCare unitComorbidity dataSerotonin levelsDisease progressionHealthy controlsPatient outcomesDisease prognosisPatient transferPatientsHealthcare resourcesPotential biomarkers
2011
Environmental Cleaning Intervention and Risk of Acquiring Multidrug-Resistant Organisms From Prior Room Occupants
Datta R, Platt R, Yokoe DS, Huang SS. Environmental Cleaning Intervention and Risk of Acquiring Multidrug-Resistant Organisms From Prior Room Occupants. JAMA Internal Medicine 2011, 171: 491-494. PMID: 21444840, DOI: 10.1001/archinternmed.2011.64.Peer-Reviewed Original ResearchConceptsMethicillin-resistant Staphylococcus aureusRisk of acquisitionPrior room occupantsVancomycin-resistant enteroccociIntensive care unitCare unitIntervention periodAcquisition of MRSAIntensive care unit roomsRetrospective cohort studyMultidrug-resistant organismsAcademic medical centerEnvironmental cleaning interventionsVRE acquisitionEligible patientsMRSA carriersVRE transmissionCardiac surgeryCohort studyMRSA acquisitionNeurosurgery unitThoracic surgeryMedical CenterVRE carriersGeneral surgery
2006
Risk of Acquiring Antibiotic-Resistant Bacteria From Prior Room Occupants
Huang SS, Datta R, Platt R. Risk of Acquiring Antibiotic-Resistant Bacteria From Prior Room Occupants. JAMA Internal Medicine 2006, 166: 1945-1951. PMID: 17030826, DOI: 10.1001/archinte.166.18.1945.Peer-Reviewed Original ResearchMeSH KeywordsBostonCarrier StateCohort StudiesCross InfectionEnterococcusFemaleGram-Positive Bacterial InfectionsHospitalizationHumansIntensive Care UnitsMaleMethicillin ResistanceMiddle AgedOdds RatioPatients' RoomsRetrospective StudiesRiskStaphylococcal InfectionsStaphylococcus aureusVancomycin ResistanceConceptsMethicillin-resistant Staphylococcus aureusPrior room occupantsVancomycin-resistant enterococciMRSA-positive patientsVRE-positive patientsRetrospective cohort studyIntensive care unitPopulation attributable riskCare of patientsRisk of transmissionRoutes of transmissionOdds of acquisitionMRSA casesVRE casesCohort studyRoutine admissionCare unitWeekly screeningExcess riskAttributable riskRelative oddsPatientsRoom occupantsAntibiotic-resistant bacteriaAdmissionImpact of Routine Intensive Care Unit Surveillance Cultures and Resultant Barrier Precautions on Hospital-Wide Methicillin-Resistant Staphylococcus aureus Bacteremia
Huang SS, Yokoe DS, Hinrichsen VL, Spurchise LS, Datta R, Miroshnik I, Platt R. Impact of Routine Intensive Care Unit Surveillance Cultures and Resultant Barrier Precautions on Hospital-Wide Methicillin-Resistant Staphylococcus aureus Bacteremia. Clinical Infectious Diseases 2006, 43: 971-978. PMID: 16983607, DOI: 10.1086/507636.Peer-Reviewed Original ResearchConceptsIntensive care unitContact isolation precautionsMRSA bacteremiaStaphylococcus aureus bacteremiaInfection control interventionsIsolation precautionsSurveillance culturesBarrier precautionsAureus bacteremiaIncidence densityHealth care-associated methicillin-resistant Staphylococcus aureus (MRSA) infectionsMethicillin-susceptible Staphylococcus aureus bacteremiaMethicillin-resistant Staphylococcus aureus (MRSA) infectionsControl interventionsMaximal sterile barrier precautionsResistant Staphylococcus aureus BacteremiaCentral venous catheter placementAlcohol-based hand rubHospital-wide reductionVenous catheter placementHand hygiene campaignRoutine surveillance culturesStaphylococcus aureus infectionInterrupted time series designBacteremia rates