2024
Regulation of cardiac function by the autonomic nervous system
Hafez O, Chang R. Regulation of cardiac function by the autonomic nervous system. Physiology 2024 PMID: 39585760, DOI: 10.1152/physiol.00018.2024.Peer-Reviewed Original ResearchAutonomic nervous systemNervous systemNeurocardiac axisIntrinsic cardiac nervous systemRegulation of cardiac functionCardiac nervous systemAutonomic control of the heartRegulating cardiovascular physiologyAutonomic dysfunctionSensory neuronsCardiac functionParasympathetic nervous systemClinical conditionsCardiac reflexesThe heartNeuronal populationsTreatment approachesCardiovascular diseaseCardiovascular physiologyMotor circuitsPhysiological roleAutonomic controlClinical fieldHeartDysfunction
2023
Cardiovascular Brain Circuits
Mohanta S, Yin C, Weber C, Godinho-Silva C, Veiga-Fernandes H, Xu Q, Chang R, Habenicht A. Cardiovascular Brain Circuits. Circulation Research 2023, 132: 1546-1565. PMID: 37228235, PMCID: PMC10231443, DOI: 10.1161/circresaha.123.322791.Peer-Reviewed Original ResearchConceptsCardiovascular systemBrain circuitsAxonal connectionsCardiovascular disease progressionIntegration centerDistant brain regionsDistinct sensory neuronsEffector neuronsAfferent inputPeripheral organsDisease progressionHormone releaseSensory neuronsImmune memoryNervous systemBrain centersImmune systemBrain regionsEfferent signalsHumoral cuesDisease hypothesisArterial treeNeuronsBrainCircuit hypothesisThe vagus nerve in cardiovascular physiology and pathophysiology: From evolutionary insights to clinical medicine
Rajendran P, Hadaya J, Khalsa S, Yu C, Chang R, Shivkumar K. The vagus nerve in cardiovascular physiology and pathophysiology: From evolutionary insights to clinical medicine. Seminars In Cell And Developmental Biology 2023, 156: 190-200. PMID: 36641366, PMCID: PMC10336178, DOI: 10.1016/j.semcdb.2023.01.001.Peer-Reviewed Original ResearchConceptsParasympathetic nervous systemNervous systemEvolutionary insightsGenetic diversityComparative biologySympathetic nervous systemParasympathetic dysfunctionVagal neuronsBlood pressureVagal efferentsAfferent innervationVagus nerveHeart diseaseCardiovascular functionCardiovascular diseaseHeart rateTherapeutic potentialCardiovascular physiologyDiseaseClinical medicineHeartBiologyDiversityInnervationNerve