1998
Cerebral blood flow velocity decreases during cognitive stimulation in Huntington's disease
Deckel A, Cohen D, Duckrow R. Cerebral blood flow velocity decreases during cognitive stimulation in Huntington's disease. Neurology 1998, 51: 1576-1583. PMID: 9855504, DOI: 10.1212/wnl.51.6.1576.Peer-Reviewed Original ResearchConceptsAnterior cerebral arteryAnterior cerebral artery flow velocityCerebral artery flow velocityBlood flow velocity changesMiddle cerebral arteryCerebral arteryArtery flow velocityHD patientsTranscranial Doppler ultrasonographyFlow velocity changesControl subjectsMaze testHuntington's diseaseCerebral blood flow velocity changesBlood flow velocity decreasesLeft anterior cerebral arteryMiddle cerebral artery velocityCognitive test scoresCerebral blood flow velocityBlood flow velocity increasePorteus Maze TestRating ScaleCognitive testingTrails TestAsymptomatic HD patients
1995
Decreased cerebral blood flow during acute hyperglycemia
Duckrow R. Decreased cerebral blood flow during acute hyperglycemia. Brain Research 1995, 703: 145-150. PMID: 8719626, DOI: 10.1016/0006-8993(95)01077-7.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAnimalsCerebrovascular CirculationElectroencephalographyGlucoseHyperglycemiaLaser-Doppler FlowmetryMaleMannitolOsmolar ConcentrationRatsRats, Sprague-DawleyConceptsAcute hyperglycemiaCerebral blood flow decreasesPlasma osmolalityBlood flow decreasePentobarbital-anesthetized ratsCerebral blood flowLaser Doppler flowmetryAcute elevationMannitol injectionCBF increaseIntraperitoneal injectionTransient depressionBlood flowBaseline levelsHyperglycemiaElectroencephalographic activityTransient increaseFlow decreasesCBFOsmolalityBrief transient increaseInjectionContinuous measureFlowmetryRats
1993
A brief hypoperfusion precedes spreading depression if nitric oxide synthesis is inhibited
Duckrow R. A brief hypoperfusion precedes spreading depression if nitric oxide synthesis is inhibited. Brain Research 1993, 618: 190-195. PMID: 8374751, DOI: 10.1016/0006-8993(93)91265-t.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsArginineCerebrovascular CirculationCortical Spreading DepressionMaleNG-Nitroarginine Methyl EsterNitric OxideParietal LobeRatsRats, Sprague-Dawley
1992
Computer simulation of the blood-brain barrier: a model including two membranes, blood flow, facilitated and non-facilitated diffusion
Oyler G, Duckrow R, Hawkins R. Computer simulation of the blood-brain barrier: a model including two membranes, blood flow, facilitated and non-facilitated diffusion. Journal Of Neuroscience Methods 1992, 44: 179-196. PMID: 1474851, DOI: 10.1016/0165-0270(92)90010-b.Peer-Reviewed Original ResearchMeSH KeywordsBlood-Brain BarrierCapillariesCerebrovascular CirculationComputer SimulationDiffusionGlucoseKineticsMembranesModels, BiologicalPhenylalanineSoftwareCortical hypoperfusion following spreading depression is not altered by tirilazad mesylate (U-74006F) in awake rats
Duckrow R, Beard D. Cortical hypoperfusion following spreading depression is not altered by tirilazad mesylate (U-74006F) in awake rats. Brain Research 1992, 572: 296-299. PMID: 1611527, DOI: 10.1016/0006-8993(92)90488-u.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntioxidantsCerebrovascular CirculationCortical Spreading DepressionElectric StimulationMalePerfusionPregnatrienesRatsRats, Inbred StrainsWakefulness
1991
Regional Cerebral Blood Flow during Spreading Cortical Depression in Conscious Rats
Duckrow R. Regional Cerebral Blood Flow during Spreading Cortical Depression in Conscious Rats. Cerebrovascular And Brain Metabolism Reviews 1991, 11: 150-154. PMID: 1983999, DOI: 10.1038/jcbfm.1991.18.Peer-Reviewed Original ResearchConceptsConscious ratsCortical depressionCBF changesRegional CBFRegional cerebral blood flowCerebral cortex contralateralConscious restrained ratsCerebral blood flowEarly transient increaseDirect current stimulationLateral frontal cortexRelative hyperperfusionCortex contralateralVascular responsesFrontal cortexRestrained ratsBlood flowCerebral hemispheresRatsCurrent stimulationTransient increaseBrain dissectionEEG activityCBFHyperperfusion
1988
Regional cerebral blood flow and glucose utilization during hyperinsulinemia
Duckrow R. Regional cerebral blood flow and glucose utilization during hyperinsulinemia. Brain Research 1988, 462: 363-366. PMID: 3191397, DOI: 10.1016/0006-8993(88)90566-5.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainCerebrovascular CirculationGlucoseHyperinsulinismMaleRatsRats, Inbred Strains
1987
Regional Cerebral Glucose Utilization During Hyperglycemia
Duckrow R, Bryan R. Regional Cerebral Glucose Utilization During Hyperglycemia. Journal Of Neurochemistry 1987, 48: 989-993. PMID: 2949062, DOI: 10.1111/j.1471-4159.1987.tb05614.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainCerebrovascular CirculationGlucoseHyperglycemiaKineticsMaleRatsRats, Inbred StrainsStreptozocinConceptsRegional cerebral blood flowRegional cerebral glucose utilizationCerebral glucose utilizationChronic hyperglycemiaAcute hyperglycemiaGlucose utilizationCerebral blood flowCerebral metabolic rateMetabolic rateIntraperitoneal injectionRestrained ratsRCMRglBlood flowHyperglycemiaKetone bodiesOxidative metabolismBrainPrevious dataStreptozotocinDecreaseRatsWeeksRegional cerebral blood flow decreases during chronic and acute hyperglycemia.
Duckrow RB, Beard DC, Brennan RW. Regional cerebral blood flow decreases during chronic and acute hyperglycemia. Stroke 1987, 18: 52-58. PMID: 2949400, DOI: 10.1161/01.str.18.1.52.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAlloxanAnimalsCerebrovascular CirculationChronic DiseaseGlucoseHyperglycemiaMaleRatsRats, Inbred StrainsStreptozocinConceptsRegional cerebral blood flowChronic hyperglycemiaAcute hyperglycemiaPlasma glucoseAcute elevationCerebral blood flow decreasesRegional cerebral blood flow decreasesIschemic cell damageBlood flow decreasePresence of hyperglycemiaCerebral blood flowMicrons/Blood flow changesAwake restrained ratsFlow reductionBrain ischemiaNeuronal damageStroke patientsCardiac arrestBlood glucosePeritoneal spaceRestrained ratsBlood flowForebrain regionsHyperglycemia