2016
50 Hz hippocampal stimulation in refractory epilepsy: Higher level of basal glutamate predicts greater release of glutamate
Cavus I, Widi GA, Duckrow RB, Zaveri H, Kennard JT, Krystal J, Spencer DD. 50 Hz hippocampal stimulation in refractory epilepsy: Higher level of basal glutamate predicts greater release of glutamate. Epilepsia 2016, 57: 288-297. PMID: 26749134, DOI: 10.1111/epi.13269.Peer-Reviewed Original ResearchConceptsBasal glutamate levelsRefractory epilepsyGlutamate effluxBasal glutamateGlutamate levelsElectrical stimulationEpileptic hippocampusGlutamate releaseSeizure groupHz stimulationBrain glutamate releaseHippocampus of patientsStimulation-induced increaseEpilepsy monitoring unitStimulation-induced changesEpileptogenic hippocampusInduced seizuresSeizure inductionSpontaneous seizuresInterictal levelsGlutamate increaseAtrophic hippocampusElectroencephalography evaluationHippocampal stimulationHippocampal electrodes
1981
Disparate recovery of resting and stimulated oxidative metabolism following transient ischemia.
Duckrow RB, LaManna JS, Rosenthal M. Disparate recovery of resting and stimulated oxidative metabolism following transient ischemia. Stroke 1981, 12: 677-686. PMID: 6272454, DOI: 10.1161/01.str.12.5.677.Peer-Reviewed Original ResearchConceptsMinutes of reperfusionTransient ischemiaMetabolic dysfunctionElectrocortical activityHours of reperfusionTransient cerebral ischemiaCarotid artery ligationOxidative responseLocal blood volumeOxidative metabolic functionCerebral ischemiaIschemic intervalArtery ligationRat brainBlood volumeElectrical stimulationCerebral surfaceReperfusionIschemiaOxidative metabolismMitochondrial redox stateDysfunctionEventual recoveryMetabolic functionsDisparate recovery